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PVTVLGAQPTKFADRHADPVTARALHVPVQQVWGYRSDRSAVSSDRPPAVHRPMSEERGDEYVVSFVESM TRRPAALVIQGEPGIGKTTRWMDVCEEARRAGVRVLSTRSGVGESALDFVGVDDLLADVEPEVFDALPIA QRTALRQVLVRSGADGTEIDRRAAIGAFRALVAELATRTPVLIGVDDVQWLDEATRDALVYTMRRVRGPV AVVVTERAVTGRGSAVSWLDLGEAGSVTRLVVRPMSVAELHRLVAGRTGRSLSRPAMARLAEMSGGNPYY ALELAQAMDSAGWVWSAGLPSSLVDATGLHRERLDADVNEVLLAAASVVGPTVDLLAAVLHRPVEQIVGS LEKAENLGIASIEAGRVGFSHPLLPHIIYSQARPGERRRIHRAVASVEPSPQRQARHLALAATTGDPEIL RALDSAAETARADAAPATAAELTEFAIGLGGDTPVRRLHAARDHLLAGDIDRSLALLEPTAQGLPDGLMR AHARVLVGGALAVRGTFGRAVDELRVALADAAGDPGLTVQIQLALAMTLSAAGDHDGADDHVRQARMHAE GMADHVLTSQALAAQVLVRTANGEVADEVSLRRAADLEQRVHHTSELPAGVHTAAPFSARVVKALVSVWT GRLNEGRAQLAEAQARYAARGSDVDVLWIQFHSAMTDIWLGRHGDAARLAEDMLLGAEQLGGTAARALAA EPRALLATLEGRESDARAEVDQVLEQVSDDVPPSNGLRTVLGFLELSLGRHAAAVDVLSPLLARSRTGGS IEIATLRFLPDLLEAAFSVGRVDEFAAWVDALEDAGTRLNRPWIVAVAARCRTMQLAARGELAAAQVTAL RALDAHRGLPMPFELARTQLIVGQLQRRLRQKRLARTTLTEALTIFEQLGTPLWAARARTELARTAESPQ QHLLTATEQRVAELVASGLTNKDVAAALYISPKTVEHNLGRVYRKLGIRNRTELGRQMDSLRDGPN*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4474 | - | - | 100% (977) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_4504 | - | 0.0 | 43.50% (938) | regulatory protein, LuxR |
| M. gilvum PYR-GCK | Mflv_1156 | - | e-175 | 42.60% (899) | regulatory protein, LuxR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2515c | - | 1e-11 | 24.60% (557) | LuxR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2488c | - | 1e-11 | 24.60% (557) | LuxR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02341 | - | 1e-10 | 24.20% (529) | putative regulatory protein |
| M. abscessus ATCC 19977 | MAB_3361 | - | 4e-48 | 27.45% (929) | LuxR family transcriptional regulator |
| M. marinum M | MMAR_0085 | - | 8e-48 | 28.24% (935) | transcriptional regulatory protein |
| M. avium 104 | MAV_0578 | - | 1e-18 | 23.67% (900) | transcriptional regulator, LuxR family protein |
| M. smegmatis MC2 155 | MSMEG_3290 | - | 5e-50 | 27.86% (944) | regulatory protein |
| M. thermoresistible (build 8) | TH_3931 | - | 7e-90 | 37.28% (625) | PUTATIVE putative regulatory protein, LuxR |
| M. ulcerans Agy99 | MUL_2555 | - | 4e-21 | 39.15% (212) | hypothetical protein MUL_2555 |
| M. vanbaalenii PYR-1 | Mvan_1863 | - | 0.0 | 44.20% (914) | regulatory protein, LuxR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb2515c|M.bovis_AF2122/97 MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Rv2488c|M.tuberculosis_H37Rv MDRRPRDFEQSRRRCRCNALRAGSMLASMSKIHPGVDVVPVDWSADGVSE
Mflv_4474|M.gilvum_PYR-GCK -----------MPVTVLGAQPTKFADRHADPVTARALHVPVQQVWGYRSD
Mvan_1863|M.vanbaalenii_PYR-1 -----------------------------------------------MSG
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 --------------------------------------------------
MSMEG_3290|M.smegmatis_MC2_155 -----------------------------------------------MVQ
MMAR_0085|M.marinum_M --------------------------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 --------------------------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 LVPTGTVTLLLADIEGATHLPGSQLDTTAIAKLDRTLTELVREHRGVCPV
Rv2488c|M.tuberculosis_H37Rv LVPTGTVTLLLADIEGATHLPGSQLDTTAIAKLDRTLTELVREHRGVCPV
Mflv_4474|M.gilvum_PYR-GCK RSAVSSDRPPAVHRPMSEERGDEYVVSFVESMTRRPAALVIQGEPGIG--
Mvan_1863|M.vanbaalenii_PYR-1 ASERSIDDP--------------HVAGFLATARSQPAGLVIEGEAGIG--
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 ---------------------------------------MLRGQAGVG--
MSMEG_3290|M.smegmatis_MC2_155 VSGVSRDDGPVAGLIGRRDECAVLDQLVDAVAGGASRALMIRGEAGVG--
MMAR_0085|M.marinum_M --------MPTVTLVGRHREQQQLQQLLDAARRGESGVLVLRGDAGIG--
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ---------MIGGELLIGRDSELAAIRRALNGADHHRGVVIAGAAGVG--
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 EQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSPDEG
Rv2488c|M.tuberculosis_H37Rv EQGEGDSFLVAFARASDAVACALGLQRAPLAPIRLRIGMHTGEVSSPDEG
Mflv_4474|M.gilvum_PYR-GCK -----------------------------------KTTRWMDVCEEARRA
Mvan_1863|M.vanbaalenii_PYR-1 -----------------------------------KTTLWLTVRQRAGDL
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 -----------------------------------KTALLRYVLGKAS--
MSMEG_3290|M.smegmatis_MC2_155 -----------------------------------KTALLDYAAARAA--
MMAR_0085|M.marinum_M -----------------------------------KTTLLTDLVDNAP--
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 -----------------------------------KTWLARAALRRAGAS
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 NCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGTYRL
Rv2488c|M.tuberculosis_H37Rv NCVGPTIDRTARLRELAHGGQTVLSGTTSDLVADLLPKDAWLNDLGTYRL
Mflv_4474|M.gilvum_PYR-GCK GVRVLSTRSGVGESALDFVGVDDLLADVEPEVFDALPIAQRTALRQVLVR
Mvan_1863|M.vanbaalenii_PYR-1 GFRVLTARAGQAESVMAFAALADLLDDVGDEVFAQLPGLQRLALDRVLLR
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 GQLIAQASGIQSEMELAFAGLQQFCAPLTKYSG-AIPDPQREALTIAFG-
MSMEG_3290|M.smegmatis_MC2_155 ELQIARIVGIQSEMELAFAGIHQLCLPLLPRLG-HLPVPQRDALEVALG-
MMAR_0085|M.marinum_M DLRVLRVRGAEMEMELTYSGVQQLCGPLMSLIG-QLPEPQLDALEIALG-
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 GEQIKWIVGTQSAQALPLGAFIGLLG------------------------
MLBr_02341|M.leprae_Br4923 -MTTALVCVACGAELRSIAKFCDECG------------------------
Mb2515c|M.bovis_AF2122/97 DDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVDEVA
Rv2488c|M.tuberculosis_H37Rv DDLPRPERVVQLCHPDLHNAFPPLRTRKVVGAHCLPAQLTRLVGRVDEVA
Mflv_4474|M.gilvum_PYR-GCK SGADGTEIDRRAAIGAFRALVAELATRTPVLIGVDDVQWLDEA-TRDALV
Mvan_1863|M.vanbaalenii_PYR-1 AGGDGPPTDQRVVAAAFVSVLQALAGESPVLIAIDDAQWLDSS-SRAAIE
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 -TRSGPPPDRFLIGLAVLSLLAAAAEHQPVLCVIDDAQWLDRV-SLQTLA
MSMEG_3290|M.smegmatis_MC2_155 -MATGSSPDRFLVGLAVLNLLADAAADRPLLCLVDDEQWLDRS-SAQVLA
MMAR_0085|M.marinum_M -RKRGRAPDRLLLGLAVLTLVGEASRASPILCVVDDAQWVDSA-SVQALA
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 ----DAMSEPLTSVRRVIETFVARQRRGRVVVGVDDAHLLDGLSALVVHQ
MLBr_02341|M.leprae_Br4923 --SPVVEAETPAEYKQVTVLFADVVGSMDIAAAVGLERLREIMTELVSRA
Mb2515c|M.bovis_AF2122/97 QVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLAPIT
Rv2488c|M.tuberculosis_H37Rv QVRGLLDVKRWVTLTGVGGVGKTRLATQVASAVADGYPDGVWYVNLAPIT
Mflv_4474|M.gilvum_PYR-GCK YTMRRVRGPVAVVVTERAVTGRGSAVSWLDLGEAGSVTR----LVVRPMS
Mvan_1863|M.vanbaalenii_PYR-1 FAVRRLRGPFGVLVTERCAPGEGATAGWLKLDRPDALER----VYVRPMT
TH_3931|M.thermoresistible__bu --------------------------------------------------
MAB_3361|M.abscessus_ATCC_1997 FVTRRLGSEPVAMLFAVRDGTDSELAGLPELTVHG-------------LR
MSMEG_3290|M.smegmatis_MC2_155 FVARRLGSESVGMIFAAREPSD-AAAGVPALVVRG-------------LR
MMAR_0085|M.marinum_M FVARRIHVDPVAMVFATRDRGPDALTGHCELSLQG-------------LE
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 LAQSGGVRLVVTVRTGSHQPDAVTALWKDDLLTRLDLEP---------LS
MLBr_02341|M.leprae_Br4923 AG-----------VIERYGGTVDKFTGDGIMAIFG-------------AP
Mb2515c|M.bovis_AF2122/97 DPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHL----
Rv2488c|M.tuberculosis_H37Rv DPALVPIAAARVLGLPDQPGRSTVDTIVRRIGDRRMLVVLDNCEHL----
Mflv_4474|M.gilvum_PYR-GCK VAELHRLVAGRTGRSLSRPAMARLAEMSGGNPYYALELAQAMDSAG----
Mvan_1863|M.vanbaalenii_PYR-1 TGQLHSLISERLGRTLARPSILRIAEISGGNPFFALELALALSDGQ----
TH_3931|M.thermoresistible__bu ------VLLARLGRTFPRAVMVQIHHISGGNPFYALELARAMDDG-----
MAB_3361|M.abscessus_ATCC_1997 AADAGTLLDSVIPGLLDERVRDRIVAETQGNPLALLELPRDMTAEE----
MSMEG_3290|M.smegmatis_MC2_155 GADARALLDSALSAPLDPRVRDQILAETDGNPLALLELPRTLTRDA----
MMAR_0085|M.marinum_M DHDARLVLSTAIPGRLNDSVAETVLAEANGNPLALLELHNALIRGE----
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 AAATREVIESTLGGPVDARCAARFRRLTGGNTLFLRQLLSDQMAAGRMRR
MLBr_02341|M.leprae_Br4923 TALEDHALRACLAALGVQEKARRLAAEVGDRDGVDLQLRVGLNSGQ---V
Mb2515c|M.bovis_AF2122/97 LDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHGEAIELF
Rv2488c|M.tuberculosis_H37Rv LDGCAALIVALLGACPALRVLATSREPIAVAGEQIWRVPPLGHGEAIELF
Mflv_4474|M.gilvum_PYR-GCK WVWSAGLP------SSLVDATGLHRERLDADVNEVLLAAASVVGPTVDLL
Mvan_1863|M.vanbaalenii_PYR-1 GSGEPPLP------ATLADVVRHRIGRLDEQTRSVLLSIACVADATVELL
TH_3931|M.thermoresistible__bu -SPLVRLP------SSLTELVRARIGRIGADARNVLLAAACSAAPTVESV
MAB_3361|M.abscessus_ATCC_1997 LAGGFGWPDGGRLAGQIEQTFLRRVQQLPAHTQTLLLAAATDPLGDVTLL
MSMEG_3290|M.smegmatis_MC2_155 LAGVFGLPGGSGVAADIEHAFGVRIGELPEPTRDLLLIAAAEPTGDAPLV
MMAR_0085|M.marinum_M LAGGYGLANATRTETQIERTFVSRLRALPSETKTFLLVAAAESTARPEWL
MUL_2555|M.ulcerans_Agy99 ----------------MPALSANLVASIDRHPERITLRCDDLQSVFAELG
MAV_0578|M.avium_104 VAGVWMWDGDVAVSASLSDTVGRQLGRLTPPLALVVDTLSQCEPLPVDLL
MLBr_02341|M.leprae_Br4923 IVGEIGSSALGYTAVGVQVGMAQRMESVAPPGVVMLSESTARLVEQTAVL
: .
Mb2515c|M.bovis_AF2122/97 TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI
Rv2488c|M.tuberculosis_H37Rv TDRAREARPELEITADNLALVTEICHRLDGIPLAIELAASRVRALALTEI
Mflv_4474|M.gilvum_PYR-GCK AAVLHRPVEQIVGSLEKAENLGIASIEAGRVGFSHPLLPHIIYSQARPGE
Mvan_1863|M.vanbaalenii_PYR-1 ARAHDVTAEEVTERLERVESTGIITVEGNRVRFTHPLLASGVYTDAGPTA
TH_3931|M.thermoresistible__bu ARAVGVDEPRVVRLLSDAVDRDIIRMDGHRICFSHPLLARGVYDDATATR
MAB_3361|M.abscessus_ATCC_1997 ARAAQQLG-IPMHAIAPAEAADLVELST-RVRFRHPLVRSAVYISANPLE
MSMEG_3290|M.smegmatis_MC2_155 WRAAARLG-IGSDAAAPAVEAELASFDT-RVTFQHPLVRSVVYRAAALDD
MMAR_0085|M.marinum_M WAAAHRLG-IGPEAAAPAEAAGLIAAQG-SVRFRHPLIRAAVYHSSSAAE
MUL_2555|M.ulcerans_Agy99 AGPGDRVAALPGDRTRRRVCGPACELSGGRFRPSARPQSCPGLTEAASPG
MAV_0578|M.avium_104 CDLASREDLVAAEAMG--LVTVERTPRALMARLAHPLFGELRRAGAGEMY
MLBr_02341|M.leprae_Br4923 GAPQTVRIKGAEDAVPARRLLRVAEPRQPTWFSESTLVGREWELATLAAM
:
Mb2515c|M.bovis_AF2122/97 VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF
Rv2488c|M.tuberculosis_H37Rv VDSLHDRFRLLTGGSRIAVRRQQTMRASVDWSHALLTGPEQVLFRRLAVF
Mflv_4474|M.gilvum_PYR-GCK RRRIHRAVASVEP---SPQRQARHLALAATTGDPEILR------------
Mvan_1863|M.vanbaalenii_PYR-1 RRAMHRTMGALES---QPELKARHLALASASGDDEIFT------------
TH_3931|M.thermoresistible__bu RRAMHRRLAEIVD---EPELQARHLAIAVGWADPQVLA------------
MAB_3361|M.abscessus_ATCC_1997 RRRIHGVLAGATDPGADPDRRAWHRAHAAAGTDEAIAW------------
MSMEG_3290|M.smegmatis_MC2_155 RRRAHRALAAATDAEVDPDRRAWHLAHAAAGPDAAAAA------------
MMAR_0085|M.marinum_M RRRVHAALAASIAGPDDDDHRVWHRAHAAEAPDAQTAD------------
MUL_2555|M.ulcerans_Agy99 R-----------------SRGPLHLAR-----------------------
MAV_0578|M.avium_104 LSTIRGRLATRLAQDQDADMQATVRRALLTLESDLDPQP-----------
MLBr_02341|M.leprae_Br4923 LDRSIGGRGSVVG-------------------------------------
Mb2515c|M.bovis_AF2122/97 PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL
Rv2488c|M.tuberculosis_H37Rv PSGFDLDGAQAAAAGGDVQRYEVVDLLSLLADKSLVVTDDSDGRTRYRLL
Mflv_4474|M.gilvum_PYR-GCK --ALDSAAETARADAAPATAAELTEFAIGLGGDTPVR---RLHAARDHLL
Mvan_1863|M.vanbaalenii_PYR-1 --ALDQAADSARARGAPAAAAELMDLAIGLGADDPLR---RMKSAENHFL
TH_3931|M.thermoresistible__bu --CLDRAAEAARLRGAPSTAAELIDMAIGLGGDSPER---RLMSARNHVD
MAB_3361|M.abscessus_ATCC_1997 --ELEQSAGRAQAKGGVLAAAAFLQRATELTADPAARGRRALAAAQSKYD
MSMEG_3290|M.smegmatis_MC2_155 --ELESSAARARSRGGACAAAAFLERATALTVDPVLRNDRALAAAAAKAE
MMAR_0085|M.marinum_M --DLERSAERARARGGLSAAASFLEHATKLTPDPFVRASRALDAAMTSLE
MUL_2555|M.ulcerans_Agy99 -----CAAELTIRRGDACQAIELLRRAGELSDRPRRREQLLASAAFVALQ
MAV_0578|M.avium_104 --ELYLESARHAMTLLDLDLADRLANAAARAGAPGAAG----VRAMNLVL
MLBr_02341|M.leprae_Br4923 -------LVGPAGIGKTRLVAEAVQLAKGLEVEVFSVFCESHATDVAFDV
Mb2515c|M.bovis_AF2122/97 ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA
Rv2488c|M.tuberculosis_H37Rv ETVRQYALEKLRESGDADAVRARHRDHYAAVAAGLDAPSVAGHERRLNQA
Mflv_4474|M.gilvum_PYR-GCK AGDIDRSLALLEPTAQGLPDGLMRAHARVLVGGALAVRGTFG--------
Mvan_1863|M.vanbaalenii_PYR-1 AGDTAKAAAALGRIDTIEPP-VLRALAASLLATVRMYENEHT--------
TH_3931|M.thermoresistible__bu AGDGDSARAILKRSSAEMTG-APRAQVLRLLGGLEILYGSYL--------
MAB_3361|M.abscessus_ATCC_1997 AAAFDAARELLGVADMTPLDPLARARATRLRAKIAFAESRVGAFGSVTVS
MSMEG_3290|M.smegmatis_MC2_155 AGAFESAQDLLAMVEATSLSDLQQAQVDVLRARLAFVTSHG--------S
MMAR_0085|M.marinum_M AGMPDSATRLVASAAAAADDELIAARCELIRAKIAFAASRG--------S
MUL_2555|M.ulcerans_Agy99 AAQLDEAERLLADAGLGGGASASALLISSFISLYRYGDVTAT-------H
MAV_0578|M.avium_104 LGRGEQAEEALRAITDGADGDASDRHYWATVRAANLVWMLGR-------P
MLBr_02341|M.leprae_Br4923 VAQLVRAVAQISGLDDRSARARVREQIPDADTQDLLLLDDLLG-------
: :
Mb2515c|M.bovis_AF2122/97 ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA
Rv2488c|M.tuberculosis_H37Rv ELEIDNLRAAFAFSRENGDTGHALLLASCLQPLWRARGRLQEGLAWFAAA
Mflv_4474|M.gilvum_PYR-GCK -RAVDELRVALADAAGDPGLTVQIQLALAMTLSAAGDHDGADD----HVR
Mvan_1863|M.vanbaalenii_PYR-1 -EAVELLRGALDDGAGNVPILVQVLLRLSFALNSIGDLDDAAR----YVR
TH_3931|M.thermoresistible__bu -DAADALRRALTDATDDAVLRARILTLLAFVEFNTGRRAAAAA----DAD
MAB_3361|M.abscessus_ATCC_1997 EAAIGLVEAARCLENLDDNLARETYLDAVGAAMYGGRLCPRGG--AVEVA
MSMEG_3290|M.smegmatis_MC2_155 DAPPLLLKAARRLGGIDPDRARAVYLDAMLAAMFAGRLATGAN--LVEVA
MMAR_0085|M.marinum_M DAPPLLLAAAQRMQRLDPSESRKAYLGAVLASILVGRMATDQHNSSPSVA
MUL_2555|M.ulcerans_Agy99 RRLVERLQSADDLDGETLTRMVNLLLAVSMFAADPALWQITDG---LVDS
MAV_0578|M.avium_104 ADAALVLDGLAARPETPAQAAARCAVQACLDAVAARCQLAAER---ARAA
MLBr_02341|M.leprae_Br4923 -----IADPAVELPRLDPDARRRRLTALINVAQLALSRPAVFV-----VE
Mb2515c|M.bovis_AF2122/97 LADHDAHPAGADPGLYARALADRALIDAVAGITDRLDDAQKALAIARDIE
Rv2488c|M.tuberculosis_H37Rv LADHDAHPAGADPGLYARALADRALIDAVAGITDRLDDAQKALAIARDIE
Mflv_4474|M.gilvum_PYR-GCK QARMHAEGM-ADHVLTSQALAAQVLVRTANGEVADEVSLRRAADLEQRVH
Mvan_1863|M.vanbaalenii_PYR-1 DAVKLAEEL-GVPGIISAALAWSVHVNIQCGRGLDEESLRRAMELYD---
TH_3931|M.thermoresistible__bu EAVECATRA-GDRGVLSQALAMRTLVTCLLGRGFDPAALHRALELEE---
MAB_3361|M.abscessus_ATCC_1997 EPARLAPAG-AQPARPSDLLLDGLARRITHGAAASAQTLGEALTLIRC--
MSMEG_3290|M.smegmatis_MC2_155 AAARSAPER-SGAAEVSDLLLDWLTAHYGRGYVAARSALGDVLSAFDG--
MMAR_0085|M.marinum_M KAASNAPAA-PHPPRALDVLLDGLVIRLTEGYVAAAPRLRSAIREYLR--
MUL_2555|M.ulcerans_Agy99 LADRLGELSVIYRDAWADAARRGRTVTQRLKEQLDRLAELEPWDVMR---
MAV_0578|M.avium_104 LDSESLPDFHAMMASLALIMAMGALGQVDDLTAVAEQALRRATTSFEAS-
MLBr_02341|M.leprae_Br4923 DVHWIDEVSDSMLADFLAVIPQTRSMALVTYRPEYHGALRHVVG------
Mb2515c|M.bovis_AF2122/97 DPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAEVLAWQ
Rv2488c|M.tuberculosis_H37Rv DPALLARALTACGGVAAYNADLARPWLAEAVGLARAVGDKWRLAEVLAWQ
Mflv_4474|M.gilvum_PYR-GCK HTSELPAGVHTAAPFSAR------------------------------VV
Mvan_1863|M.vanbaalenii_PYR-1 --STLDVPIIFRAPF----------------------------------V
TH_3931|M.thermoresistible__bu -PGSGDLGITRTSGL-----------------------------------
MAB_3361|M.abscessus_ATCC_1997 -EAD-RPANTSWMEQAFP------------------------------IA
MSMEG_3290|M.smegmatis_MC2_155 -EAD-DLP-LNRMLLAS---------------------------------
MMAR_0085|M.marinum_M -ERDIGVAEPGWHDLTA---------------------------------
MUL_2555|M.ulcerans_Agy99 --------------------------------------------------
MAV_0578|M.avium_104 -------HMRFWFGAVYG--------------------------------
MLBr_02341|M.leprae_Br4923 --------------------------------------------------
Mb2515c|M.bovis_AF2122/97 AYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAANLWQGN
Rv2488c|M.tuberculosis_H37Rv AYVGFAGEGDPGATRAAGEEARSLADEIGDAFLSRSCRWALAAANLWQGN
Mflv_4474|M.gilvum_PYR-GCK KALVSVWTGRLNEGRAQLAEAQARYAARGSDVDVLWIQFHSAMTDIWLGR
Mvan_1863|M.vanbaalenii_PYR-1 HALVMSWTGRLEQAHRELTAMRAVCVERGAESDMMAIAGFLAINHLWRGQ
TH_3931|M.thermoresistible__bu HAMLLAYTGRFDAAVEVMRAVARHCRDRGEGLDLTYIALHRVLVELWRGE
MAB_3361|M.abscessus_ATCC_1997 LESATHEVWDDDMWHHLATRAVHIAREVGALSLLPAALIYRAGMHVHAGE
MSMEG_3290|M.smegmatis_MC2_155 --TAAHYAWDDVRLDVFTAHHVERARATGALSEVPIALNSRAIALLFFGD
MMAR_0085|M.marinum_M --RVCLDLFDQDAYNFLAARQVEDLRAAGALTMLPVALVTFAGVCVSAGN
MUL_2555|M.ulcerans_Agy99 VALAGYYVDLIDDFRSVLVPLADREIEGGAATIALATLALVAAYQLASGQ
MAV_0578|M.avium_104 --RACRLTGRIDEFVSTARRLADSARDVPG-LAYANLALLLGNAELARGA
MLBr_02341|M.leprae_Br4923 --AQIIAVAPLSDVETSTLVAELLGLDQSVTQIGELITERAAGNPFFAQE
.
Mb2515c|M.bovis_AF2122/97 LEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDTEAAAAAQAS
Rv2488c|M.tuberculosis_H37Rv LEAAVGLSREVIGESDAAHDMVSSCAGQACLAHALAHRGDTEAAAAAQAS
Mflv_4474|M.gilvum_PYR-GCK HGDAARLAEDMLLGAEQLGGTAARALAAEPRALLATLEGRESDARAEVDQ
Mvan_1863|M.vanbaalenii_PYR-1 IAEAEAEASEAVERAEQLGGDDVLIIPMTVRGTLAAYAGRVEDARADARW
TH_3931|M.thermoresistible__bu VRAAATIAEEAIESAAVLDGDLPRGVVLLLRQALATYAGRVDDARGDGAR
MAB_3361|M.abscessus_ATCC_1997 LDAAAELVQEADAISAATG----HAPIRYHSLILAAWRGSEPTAIRLIDE
MSMEG_3290|M.smegmatis_MC2_155 LDGAADAVDEIQAADDATG----ALLAPYAEVGLAAMRGDLARTASLVDA
MMAR_0085|M.marinum_M FGQADALLDESAAIIAATG----APPRPAIKTYLAAYRGQEQICREGVQQ
MUL_2555|M.ulcerans_Agy99 WAEAVDTSQRGVALCSQHHYELFGYQLRGYLGVISACRGDVVRARELAAQ
MAV_0578|M.avium_104 AAEAARLVQEALAGAQIHEVTSGLRPASYFALAEAHGRLGHPAQANEAIA
MLBr_02341|M.leprae_Br4923 ITRELAERGVLTGERGRYACSTDVAEVCVPATLQATIAARIDRLSPPAKQ
Mb2515c|M.bovis_AF2122/97 IDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRFFGASAAAI
Rv2488c|M.tuberculosis_H37Rv IDTAVGLSPVLSGSACSALVFATLAAGDVAAAEHARESATRFFGASAAAI
Mflv_4474|M.gilvum_PYR-GCK VLEQVSDDVPP--SNGLRTVLGFLELSLGRHAAAVDVLSPLLARS-RTGG
Mvan_1863|M.vanbaalenii_PYR-1 VLDAVKNRQTSHIADWPGMTLCFLEESLRNHREALQALDAKFLDP-KQMR
TH_3931|M.thermoresistible__bu AAAIFARSGSAILTTLTTSLTGFLELSVGDHVAAIATLRPLLPILGPDLE
MAB_3361|M.abscessus_ATCC_1997 AMRDGAARGEGRLLGAMGYAAGVLNNSLGRYELAFMAARRACEH------
MSMEG_3290|M.smegmatis_MC2_155 TVAAVTARGEGNGLTVAWWAEAVLHNGFGSARKALEAASRAAAFP-----
MMAR_0085|M.marinum_M TVDSAASRGEGYDVSVAMYAAAILHNGLGQYQEAFNAAASGARY------
MUL_2555|M.ulcerans_Agy99 VRVWAEPRRVGFLTGAVAQIAILCSFAEGDYESAYLQATAITAPG--EFP
MAV_0578|M.avium_104 GARSCVPPDFLFMHTGLALATGWALAAGGQLREAVATAQAAARLA-----
MLBr_02341|M.leprae_Br4923 LLVAAAVIGFRFGSDLLASLG--IDLSVDELIDANLVDQVRFTAP-----
.
Mb2515c|M.bovis_AF2122/97 INDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTTRCRIEIAQ
Rv2488c|M.tuberculosis_H37Rv INDPTSSAQISCARGDLNAAHRLADGAASITRGVHRARALTTRCRIEIAQ
Mflv_4474|M.gilvum_PYR-GCK SIEIATLRFLPDLLEAAFSVGRVDEFAAWVDALEDAGTRLNRPWIVAVAA
Mvan_1863|M.vanbaalenii_PYR-1 STELMYAWHLPDVIEAMVGVGRLDEAESLTGALEQNGIEHDRHWMKAVGM
TH_3931|M.thermoresistible__bu GTEIITAGFLPDLVEAQVLMGLLDDAEPLVQALTRNGRRLDRPWMLAVAA
MAB_3361|M.abscessus_ATCC_1997 EDLGLYSWCLIELIEAAVRCGEHDTAVKAFGQLEERALAAQSDWSQGMVA
MSMEG_3290|M.smegmatis_MC2_155 PELASANWALIELVEAATRCGAVETAAEAAADLAELTTSSGTDWALGLAA
MMAR_0085|M.marinum_M DDVGMCGYLLGELIEAAVRCKEHNAATEALGRLLKRTKASGTPTALGIGA
MUL_2555|M.ulcerans_Agy99 PLALHATRTLFDLVEAAVHTDRLNEARRHVRAAKRLQFADAPPRLAIATG
MAV_0578|M.avium_104 -----RDRGQPTHELACIQAAAQWGDAAGAVRARALADALSLPLADAIAC
MLBr_02341|M.leprae_Br4923 ----VEYAFRHPLIRTVAYESQLKSDRARLHRRLAAAIEARAPHSVDQHA
Mb2515c|M.bovis_AF2122/97 GDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGSNREAVRLF
Rv2488c|M.tuberculosis_H37Rv GDRHRAERDAHDALGVAASIGAYLWVPDILECLASVMADAGSNREAVRLF
Mflv_4474|M.gilvum_PYR-GCK RCRTMQLAARGELAAAQVTALRALDAHRGLPMPFELARTQLIVGQLQRRL
Mvan_1863|M.vanbaalenii_PYR-1 RCRAMLLAARGDVIAAEQTAHRAMAEHDRLPMPFERARTQLLLGQLQRRL
TH_3931|M.thermoresistible__bu RCRAMMLAARGDLAGAVAAVX---XXGRRRSGPGAAARHRGAVRRRRRPD
MAB_3361|M.abscessus_ATCC_1997 RSRALITVGH----DAEPHYREAIQRLTNTRISAHLARAHLIYGEWLRRC
MSMEG_3290|M.smegmatis_MC2_155 RARALVSGPA----ESERWYLESIERLENTRARAELARSRLVYGEWLRRE
MMAR_0085|M.marinum_M SATALVSDGS----IADAAYREAITHLRRSPVAVHLARTHLTYGEWLRRE
MUL_2555|M.ulcerans_Agy99 AAEALCASDE----RAPALFEKVLGHPAVASFPFEHARIRLAYGMRLRRL
MAV_0578|M.avium_104 HAEALR-AGNGEALLTVAAAYRAIGDAAAAADAAAQASAAFVEGQQHQRG
MLBr_02341|M.leprae_Br4923 VLIAEHLEAAGDLHAAYGWHMRAAAWATNQDVRAARVSWEHATKIADALT
Mb2515c|M.bovis_AF2122/97 GAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAWAEGTALSI
Rv2488c|M.tuberculosis_H37Rv GAADAARGRMGAVRFGIYQAGCNSSLATLRKSMGDSEFDDAWAEGTALSI
Mflv_4474|M.gilvum_PYR-GCK RQKRLARTTLTEALTIFEQLGT-----------------PLWAARARTEL
Mvan_1863|M.vanbaalenii_PYR-1 RQKNTAATNLNEALRTFEEMGT-----------------PLWVRRARAEL
TH_3931|M.thermoresistible__bu RRG--------------ARAGR-----------------PAGGTQPVGLL
MAB_3361|M.abscessus_ATCC_1997 NRRSDARTELTAAHGSFVNMGT-----------------AAFAERAEREL
MSMEG_3290|M.smegmatis_MC2_155 RRRTAARSELRTAHEMFSAMGM-----------------SAFAARAQREL
MMAR_0085|M.marinum_M RRRSEARSQLRIAYDMFAQMGA-----------------AGFAERARREL
MUL_2555|M.ulcerans_Agy99 RRYRNARVVLRAAAEIFAGLGA-----------------EPWTQRARNEL
MAV_0578|M.avium_104 RYAAALAGELAEECGG----------------------------LCTPAL
MLBr_02341|M.leprae_Br4923 AEDPHR---------------------------------AAMCIAPRTRL
:
Mb2515c|M.bovis_AF2122/97 DEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNKEIGVRLFI
Rv2488c|M.tuberculosis_H37Rv DEAIAYAQRGRGARKRPTSGWGALTPTELEVALLVGEGLSNKEIGVRLFI
Mflv_4474|M.gilvum_PYR-GCK ARTAESPQQ------------HLLTATEQRVAELVASGLTNKDVAAALYI
Mvan_1863|M.vanbaalenii_PYR-1 ARAVVAPAE----------GLSQLTPSEQRVAEMAASGATNKDIASAMFI
TH_3931|M.thermoresistible__bu VRTVP--------------------RRTARHGRIPAPGRX----------
MAB_3361|M.abscessus_ATCC_1997 RATGAKVRK------RSASSEKALTAQEAQIARMAGQGLTNQEIAAQLFI
MSMEG_3290|M.smegmatis_MC2_155 AAAGDRIRET-----VIAAVDHRLTAQEAHIARLARDGLSNPEIGARLFI
MMAR_0085|M.marinum_M SATGEAVYV------QPTGITVDLTTQESHIARLARDGYTNAEIAGLLFI
MUL_2555|M.ulcerans_Agy99 RAAGTAVRHS------AAVGPAPLTAQERLVAELAAKGLSNKEIAARLCL
MAV_0578|M.avium_104 RTPAG----------------LKLSGRQRDVIELAVAGLSNRQIAERLVM
MLBr_02341|M.leprae_Br4923 CGIAWR-------------------GRFNSSSGFDEVRQLCNATGDKAPL
:
Mb2515c|M.bovis_AF2122/97 SPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP
Rv2488c|M.tuberculosis_H37Rv SPRTVHSHLTHVYTKLGLSSRLQLAQQAARRGESERGPSRP
Mflv_4474|M.gilvum_PYR-GCK SPKTVEHNLGRVYRKLGIRNRTELGRQMDSLRDGPN-----
Mvan_1863|M.vanbaalenii_PYR-1 SAKTVEHNLTKIYRKLGISSRAELGRRMDRAGEP-------
TH_3931|M.thermoresistible__bu RGDRADRAPGSQRGGRAGPADRTRGAVADAAGR--------
MAB_3361|M.abscessus_ATCC_1997 SSHTVEWHLRKVFAKRGITSRRQLR------SGR-------
MSMEG_3290|M.smegmatis_MC2_155 SARTVQYHLGKVFTKLGITSRSQLDGVLGHVTDR-------
MMAR_0085|M.marinum_M SARTVEWHLSKIFAKLGVTSRRELRAILMESP---------
MUL_2555|M.ulcerans_Agy99 SPRTVGAHLYRLFPKLGVTNRAGLHDALDAIHAAPDQI---
MAV_0578|M.avium_104 SVRTVEGHIYRACQRVGAQSRDELATIIRSRPAGRES----
MLBr_02341|M.leprae_Br4923 AVATVGPAIDHVYQDRLH-----------------------
.