For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGARLTLAGGNSAGLAELVNGAGIDD AAVVTCRPDSLADAQQMVEAALGRYGRLDGVLVASGSNHVAPITEMAVEDFDAVMDANVRGAWLVCRAAG RVLLEQGQGGSVVLVSSVRGGLGNAAGYSAYCPSKAGTDLLAKTLAAEWGGHGIRVNALAPTVFRSAVTE WMFTDDPKGRATREAMLARIPLRRFAEPEDFVGALIYLLSDASSFYTGQVMYLDGGYTAC
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1741 | - | - | 100% (270) | oxidoreductase |
| M. bovis AF2122 / 97 | Mb1963c | - | 4e-32 | 32.56% (258) | short chain dehydrogenase |
| M. bovis AF2122 / 97 | Mb1976 | - | 6e-31 | 35.83% (254) | short-chain type dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2071 | - | 2e-29 | 36.33% (245) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1714 | - | 1e-151 | 100.00% (270) | oxidoreductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 9e-19 | 29.51% (244) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4490c | - | 5e-68 | 48.83% (256) | oxidoreductase |
| M. marinum M | MMAR_2849 | - | 2e-32 | 33.59% (256) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2775 | - | 1e-32 | 30.98% (255) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3607 | - | 6e-36 | 34.39% (253) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2623 | - | 8e-34 | 35.27% (258) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_2885 | - | 7e-30 | 35.86% (251) | short-chain type dehydrogenase/reductase |
| M. vanbaalenii PYR-1 | Mvan_0894 | - | 3e-33 | 35.83% (254) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1741|M.bovis_AF2122/97 --MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGAR
Rv1714|M.tuberculosis_H37Rv --MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGAR
MAB_4490c|M.abscessus_ATCC_199 --------MFDDP---RALFDIAGKSAIVIGATGSLGQIASRALAGAGAN
MMAR_2849|M.marinum_M -------------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQ
MAV_2775|M.avium_104 ---------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGAR
TH_2623|M.thermoresistible__bu --MGVLDK-----------FRLDDKVVIVTGASSGLGVAFARACAEAGAD
Mvan_0894|M.vanbaalenii_PYR-1 MTVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALALRSAGAE
MSMEG_3607|M.smegmatis_MC2_155 -------MTQAQELSVDFDFRLDGKVALVTGAASGIGAAIASAYATKGAR
MUL_2885|M.ulcerans_Agy99 -------MRYP---------DLAGKATIVTGAGAGIGLAIAERLAAEGAA
Mflv_2071|M.gilvum_PYR-GCK ---MSNSSERVAVIVG---------------GASGIGWATAQALAAEGCR
MLBr_01807|M.leprae_Br4923 ---MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR
. .:* : *
Mb1741|M.bovis_AF2122/97 LTLAGGNSAGLAELVNGAGIDD-AAVV--TCRPDSLADAQQMVEAALGRY
Rv1714|M.tuberculosis_H37Rv LTLAGGNSAGLAELVNGAGIDD-AAVV--TCRPDSLADAQQMVEAALGRY
MAB_4490c|M.abscessus_ATCC_199 VAICGSREDALSDLRDELAAAP-GCIVPIARRPDSESASDAIVKETIEAF
MMAR_2849|M.marinum_M VAVAARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGEL
MAV_2775|M.avium_104 VAIAARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAEL
TH_2623|M.thermoresistible__bu VVLAARRVERLQQTAEQVRATG-RRALTVATDVVDPQQCQEMVDAAMTEF
Mvan_0894|M.vanbaalenii_PYR-1 VVVAARRADRLAELCEAHEGLS-----AVSCDVADPASIESAYQCVEERV
MSMEG_3607|M.smegmatis_MC2_155 IAAVDLNAEGAEALAAQLGGDR-GAHRGFACDVADAASVQAAADAVAAEF
MUL_2885|M.ulcerans_Agy99 VLCADIDGASAEQAAAKIG----SGAVGYQVDVSAEEQVAGMVEACVTSF
Mflv_2071|M.gilvum_PYR-GCK VTIADRNADGARERASELGSGH----RAEAVDVTDEDSVARLFDAIG---
MLBr_01807|M.leprae_Br4923 VAVTHR--------ASVVPDWF----FGVECDVTDNDAIGAAFKAVEEHQ
: .
Mb1741|M.bovis_AF2122/97 GRLDGVLVASGSNHVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLLE
Rv1714|M.tuberculosis_H37Rv GRLDGVLVASGSNHVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLLE
MAB_4490c|M.abscessus_ATCC_199 GGVDILVVASGVNEVAPAVDMQPARFEAVLDANVTSTWLAVRSAGRAMIE
MMAR_2849|M.marinum_M GGIDIAVCNAGIVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMVD
MAV_2775|M.avium_104 GGIDIAVCNAGIISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVR
TH_2623|M.thermoresistible__bu GRVDVLVNNAGVGTAVPATRETPEEFRTVIDINLNGSYWAAQACGR--VM
Mvan_0894|M.vanbaalenii_PYR-1 GAVDILVNNAGTSIPARAEDESLTDFQYVLDVNLVGAFRLTQLVGRKMIE
MSMEG_3607|M.smegmatis_MC2_155 GRIDILVNSAGVARLAPAEELSLQDWDSTLAINLSGTFLMCQAVGKRMLE
MUL_2885|M.ulcerans_Agy99 GGLDKLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVE
Mflv_2071|M.gilvum_PYR-GCK -PLDIAVNCAGFSNVGLITDMAAEDFRAVIDVCLNGAFIVTKHAGRHLRR
MLBr_01807|M.leprae_Br4923 GPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIK
:: : :* : : . : : .
Mb1741|M.bovis_AF2122/97 QGQGGSVVLVSSVRGGLG-NAAGYSAYCPSKAGTDLLAKTLAAEWG-GHG
Rv1714|M.tuberculosis_H37Rv QGQGGSVVLVSSVRGGLG-NAAGYSAYCPSKAGTDLLAKTLAAEWG-GHG
MAB_4490c|M.abscessus_ATCC_199 RGRGGKIILTSSARGKLG-HPAGYTAYCASKAAVDGLVRSFGCEWG-RYG
MMAR_2849|M.marinum_M QGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELA-PHQ
MAV_2775|M.avium_104 QGRGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFA-PHD
TH_2623|M.thermoresistible__bu RPGS-SIVNISSILGITTASLP-QAAYSASKAGVIGLTRDLAQQWTPRKG
Mvan_0894|M.vanbaalenii_PYR-1 RGEG-SIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQWA-RYN
MSMEG_3607|M.smegmatis_MC2_155 AGGG-AIVNMASQAATVA--LDQHVAYCASKFGVVGVSKVLAAEWG-GRG
MUL_2885|M.ulcerans_Agy99 RGGG-AIVNMSSLAGHIG--VGGTAAYGMSKAGISHLSRVTAAELR-SAN
Mflv_2071|M.gilvum_PYR-GCK G--G-SLVQISSLNGRQP--AAGMSAYCAAKAGLSMLTQVAALEMG-PRG
MLBr_01807|M.leprae_Br4923 QRFG-RYIFMGSVVGLSG--VPGQANYAASKSGLIGMARSLARELG-SRS
. : .* . * :* . : : . :
Mb1741|M.bovis_AF2122/97 IRVNALAPTVFRSAVTEWMFT-DDPKGRATREAMLARIPLRRFAEPEDFV
Rv1714|M.tuberculosis_H37Rv IRVNALAPTVFRSAVTEWMFT-DDPKGRATREAMLARIPLRRFAEPEDFV
MAB_4490c|M.abscessus_ATCC_199 ITVNGLAPTVFRSPLTSWMFT-DEPAAQATRENFLSRIPLGRLGEPEDLA
MMAR_2849|M.marinum_M IRVNSVSPGYIRTELVEPLAD-YHALWEP-------KIPLGRMGRPEELT
MAV_2775|M.avium_104 IRVNSVSPGYIRTELVEPLHE-YHRQWQP-------KIPLGRMGRPDELA
TH_2623|M.thermoresistible__bu IRVNAIAPGFFKSEMTDQYKP-GYLDSQMPR------VLMGRTGDPEELA
Mvan_0894|M.vanbaalenii_PYR-1 VRVNALAPGFFPSELTTELLD-DDAGGAYIRR----NTPMARAGRAGELS
MSMEG_3607|M.smegmatis_MC2_155 VRVNTISPTVVLTELGHKA---WDGPRGD-ALKKLIP--TGRFAYPDEIA
MUL_2885|M.ulcerans_Agy99 VRSNALLPAFVDTPMQQSAMAMFDEVLGTGGANTMIARLQGRMARPEEMA
Mflv_2071|M.gilvum_PYR-GCK IRVNAVAPGFVHTPLTAAAASVPGVVEDYVDN-----TALGRAGTPEDIA
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTEMTRAMDSK--YQEAALQA-----IPLGRIGAVEEIA
: * : * . : : * . ::
Mb1741|M.bovis_AF2122/97 GALIYLLSDASSFYTGQVMYLDGGYTAC-----------------
Rv1714|M.tuberculosis_H37Rv GALIYLLSDASSFYTGQVMYLDGGYTAC-----------------
MAB_4490c|M.abscessus_ATCC_199 GPILFLSAPASDFLTGHVVYPDGGYTAG-----------------
MMAR_2849|M.marinum_M GLYLYLASAASSYMTGSDIVIDGGYTCP-----------------
MAV_2775|M.avium_104 GIYLYLASAASSYMTGSDIVIDGGYSCP-----------------
TH_2623|M.thermoresistible__bu ATLVWLVSDAGGYVTGQTIVVDGGITIT-----------------
Mvan_0894|M.vanbaalenii_PYR-1 GALLLLASGAGSFITGQVIAVDGGWTAR-----------------
MSMEG_3607|M.smegmatis_MC2_155 AAAVFLASDAAAMINGADLVIDGGYTIK-----------------
MUL_2885|M.ulcerans_Agy99 RIVAFLLPDDSSMITGTTQIADGGTIAALW---------------
Mflv_2071|M.gilvum_PYR-GCK AAVVFLCSPGTSWMTGEVLDINGGAHLKRYPDVMGHVMKLMEPAS
MLBr_01807|M.leprae_Br4923 GAVSFLASEDAGYISGAVIPVDGGLGMGH----------------
* . .* :**