For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGARVAIAARDFEALQRTADELTAGGTGGVVAIRCDVTQ PDEVSGMVDRMIAELGGIDIAVCNAGIISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVRQGRGG AIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHDIRVNSVSPGYIRTELVEPLHEYHRQW QPKIPLGRMGRPDELAGIYLYLASAASSYMTGSDIVIDGGYSCP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_2775 | - | - | 100% (254) | short chain dehydrogenase |
| M. avium 104 | MAV_1572 | - | 9e-41 | 38.06% (247) | short chain dehydrogenase |
| M. avium 104 | MAV_5088 | fabG | 7e-39 | 36.33% (245) | 3-ketoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 1e-108 | 75.98% (254) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_4369 | fabG | 4e-40 | 37.65% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1928c | - | 1e-108 | 75.98% (254) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-31 | 34.30% (242) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4490c | - | 6e-40 | 37.50% (256) | oxidoreductase |
| M. marinum M | MMAR_2849 | - | 1e-112 | 79.13% (254) | short-chain type dehydrogenase/reductase |
| M. smegmatis MC2 155 | MSMEG_3604 | - | 7e-43 | 40.71% (253) | sorbitol utilization protein SOU2 |
| M. thermoresistible (build 8) | TH_3693 | - | 8e-41 | 38.46% (247) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3898 | fabG | 5e-40 | 37.76% (241) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_0441 | - | 7e-41 | 37.85% (251) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4369|M.gilvum_PYR-GCK -----------MSLLTGQT----AVITGGAQGLGFAIAQRFVDEGARVVL
TH_3693|M.thermoresistible__bu -----------VSLLAGQT----AVVTGGARGLGYAIAERFIAEGARVVI
MUL_3898|M.ulcerans_Agy99 -----------MCGAHRDRGYVYPVVTGGAQGLGLAIAERFVSEGARVVL
Mb1963c|M.bovis_AF2122/97 ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
MMAR_2849|M.marinum_M ----------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQVAV
MAV_2775|M.avium_104 ------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGARVAI
MSMEG_3604|M.smegmatis_MC2_155 ----------MDVRSAFDLSGRTALVTGGNQGLGKAFAIALAQAGARVSF
MAB_4490c|M.abscessus_ATCC_199 --------MFDDPRALFDIAGKSAIVIGATGSLGQIASRALAGAGANVAI
Mvan_0441|M.vanbaalenii_PYR-1 ------MTDAAPPANPFDLTGHVAVVTGGGSGIGLGMAEGLARAGATVAI
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
:: *. .:* : * * .
Mflv_4369|M.gilvum_PYR-GCK GDVNLEATQEAAEKLGGAD--VAHAVRCDVTSSAEVDALVAAAVDTFGAL
TH_3693|M.thermoresistible__bu GDIDESATRAAADSLGGAD--VAVGMRCDVTRSDEVEALVGAAVKRFGSL
MUL_3898|M.ulcerans_Agy99 GDVNLEATEAAAKQLGGGE--VAVAVRCDVTKADEVETLLQAALERFGGL
Mb1963c|M.bovis_AF2122/97 AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Rv1928c|M.tuberculosis_H37Rv AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
MMAR_2849|M.marinum_M AARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGELGGI
MAV_2775|M.avium_104 AARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAELGGI
MSMEG_3604|M.smegmatis_MC2_155 SGRNAERNEKTAAEAAAAG-HQLHAITADITRAEDVERMTAEAIEALGHI
MAB_4490c|M.abscessus_ATCC_199 CGSREDALSDLRDELAAAP-GCIVPIARRPDSESASDAIVKETIEAFGGV
Mvan_0441|M.vanbaalenii_PYR-1 LGRSAQRLDSAAATLRSHG-NPVLPVVCDVTDEQAVTDAMARIRSEFGWL
MLBr_01807|M.leprae_Br4923 THRASVVPD------------WFFGVECDVTDNDAIGAAFKAVEEHQGPV
: * :
Mflv_4369|M.gilvum_PYR-GCK DIMVNNAGIT-RDATMRKMTEDDFDKVIAVHLKGTWNGLRAAAAIMRENK
TH_3693|M.thermoresistible__bu DVMVNNAGIT-RDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMREQK
MUL_3898|M.ulcerans_Agy99 DIMVNNAGIT-RDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENK
Mb1963c|M.bovis_AF2122/97 DIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQG
Rv1928c|M.tuberculosis_H37Rv DIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQG
MMAR_2849|M.marinum_M DIAVCNAGIV-SVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMVDQG
MAV_2775|M.avium_104 DIAVCNAGII-SVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVRQG
MSMEG_3604|M.smegmatis_MC2_155 DILVNNAGTC-HHGESWTVTEEQWDDVFDLNVKALWACSLAVGAHMRERG
MAB_4490c|M.abscessus_ATCC_199 DILVVASGVN-EVAPAVDMQPARFEAVLDANVTSTWLAVRSAGRAMIERG
Mvan_0441|M.vanbaalenii_PYR-1 DSCFANAGVRGTFTPTLDTSLAEFREVTRVDLDGVFVTLREAARQMIGAG
MLBr_01807|M.leprae_Br4923 EVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
: . :* : : .: . : .. *
Mflv_4369|M.gilvum_PYR-GCK -RGVIVNMSSISGKVG--MIGQTNYSAAKAGIVGMTKAASKELAYLGVRV
TH_3693|M.thermoresistible__bu -RGAIVNMSSISGKVG--MVGQTNYSAAKAGIVGMTKAASKELAYLGVRV
MUL_3898|M.ulcerans_Agy99 -RGAIVNMSSVSGKVG--MVGQTNYSAAKAGIVGMTKAAAKELAHVGVRV
Mb1963c|M.bovis_AF2122/97 QGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRV
Rv1928c|M.tuberculosis_H37Rv QGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRV
MMAR_2849|M.marinum_M LGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQIRV
MAV_2775|M.avium_104 RGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHDIRV
MSMEG_3604|M.smegmatis_MC2_155 -SGSVVNIGSMSGIIVNRPQMQPAYNASKAAVHHLTKSLAAEWAPLGIRV
MAB_4490c|M.abscessus_ATCC_199 RGGKIILTSSARGKLG-HPAGYTAYCASKAAVDGLVRSFGCEWGRYGITV
Mvan_0441|M.vanbaalenii_PYR-1 RGGSLVGVSSLG--AVQGMPRQPAYAASKAGVTSLMDSLAVEFARYGIRA
MLBr_01807|M.leprae_Br4923 -FGRYIFMGSVVGLSG--VPGQANYAASKSGLIGMARSLARELGSRSITA
* : .* * ::*:.: : : . * . : .
Mflv_4369|M.gilvum_PYR-GCK NAIQPGLIRSAMT------EAMPQRIWDSKVAEVPLGRAGEPDEVAKVAL
TH_3693|M.thermoresistible__bu NAIQPGLIRSAMT------EAMPQRIWDEKLAEIPMGRAGEPEEVAKVAL
MUL_3898|M.ulcerans_Agy99 NAIAPGLIRSAMT------EAMPQRIWDQKLAEVPMGRAGEPSEVASVAL
Mb1963c|M.bovis_AF2122/97 NSVSPGYILTEL------VEP-YTEYQPLWEPKIPLGRLGRPEELAGLYL
Rv1928c|M.tuberculosis_H37Rv NSVSPGYILTEL------VEP-YTEYQPLWEPKIPLGRLGRPEELAGLYL
MMAR_2849|M.marinum_M NSVSPGYIRTEL------VEP-LADYHALWEPKIPLGRMGRPEELTGLYL
MAV_2775|M.avium_104 NSVSPGYIRTEL------VEP-LHEYHRQWQPKIPLGRMGRPDELAGIYL
MSMEG_3604|M.smegmatis_MC2_155 NALAPGYVKTDM------APVDRPEFKRYWIDDTPQLRYAVPEEIAPSVV
MAB_4490c|M.abscessus_ATCC_199 NGLAPTVFRSPLTSWMFTDEPAAQATRENFLSRIPLGRLGEPEDLAGPIL
Mvan_0441|M.vanbaalenii_PYR-1 NTIQPGWFATEMT----ADGMADERFRARVLPRVPVRRWGAAEDVGGIAV
MLBr_01807|M.leprae_Br4923 NVVAPGFIDTEMT------RAMDSKYQEAALQAIPLGRIGAVEEIAGAVS
* : * . : : * * . .::
Mflv_4369|M.gilvum_PYR-GCK FLASDLSSYMTGTVLEVTGGRHL--
TH_3693|M.thermoresistible__bu FLASDLSSYMTGTVLEVTGGRHL--
MUL_3898|M.ulcerans_Agy99 FLACDLSSYMTGTVLDVTGGRFI--
Mb1963c|M.bovis_AF2122/97 YLASEASSYMTGSDIVIDGGYTCP-
Rv1928c|M.tuberculosis_H37Rv YLASEASSYMTGSDIVIDGGYTCP-
MMAR_2849|M.marinum_M YLASAASSYMTGSDIVIDGGYTCP-
MAV_2775|M.avium_104 YLASAASSYMTGSDIVIDGGYSCP-
MSMEG_3604|M.smegmatis_MC2_155 FLASDAASFITGSVLVADGGYTAW-
MAB_4490c|M.abscessus_ATCC_199 FLSAPASDFLTGHVVYPDGGYTAG-
Mvan_0441|M.vanbaalenii_PYR-1 YLASPASAYHTGDVLRLDGGYLKF-
MLBr_01807|M.leprae_Br4923 FLASEDAGYISGAVIPVDGGLGMGH
:*:. : : :* : **