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LNHPDLAGKVAIVTGAGAGIGLAVARRLADEGCHVLCADIDGDAADAAATKIGCGAAACRVDVSDEQQII AMVDACVAAFGGVDKLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGGAIVNLS SLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLPAFVDTPMQQTAMAMFDGALGAGGARS MIARLQGRMAAPEEMAGIVVFLLSDDASMITGTTQIADGGTIAALW
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb1976 | - | - | 100% (256) | short-chain type dehydrogenase/reductase |
M. bovis AF2122 / 97 | Mb1385 | fabG | 2e-38 | 35.89% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. bovis AF2122 / 97 | Mb0792 | - | 2e-37 | 40.64% (251) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. gilvum PYR-GCK | Mflv_4505 | - | 4e-39 | 36.25% (251) | short-chain dehydrogenase/reductase SDR |
M. tuberculosis H37Rv | Rv1941 | - | 1e-142 | 100.00% (256) | short-chain type dehydrogenase/reductase |
M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-29 | 34.41% (247) | 3-oxoacyl- |
M. abscessus ATCC 19977 | MAB_4680c | - | 7e-38 | 39.36% (249) | putative short-chain dehydrogenase/reductase |
M. marinum M | MMAR_2869 | - | 1e-112 | 77.73% (256) | short-chain type dehydrogenase/reductase |
M. avium 104 | MAV_5088 | fabG | 2e-44 | 44.76% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. smegmatis MC2 155 | MSMEG_3607 | - | 4e-42 | 40.73% (248) | short chain dehydrogenase |
M. thermoresistible (build 8) | TH_4254 | - | 8e-41 | 37.30% (252) | PUTATIVE putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol |
M. ulcerans Agy99 | MUL_2885 | - | 1e-111 | 76.95% (256) | short-chain type dehydrogenase/reductase |
M. vanbaalenii PYR-1 | Mvan_3999 | - | 1e-108 | 76.17% (256) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment Mb1976|M.bovis_AF2122/97 MNHPD-------------LAGKVAIVTGAGAGIGLAVARRLADEGCHVLC Rv1941|M.tuberculosis_H37Rv MNHPD-------------LAGKVAIVTGAGAGIGLAVARRLADEGCHVLC MMAR_2869|M.marinum_M MRYPD-------------LAGKATIVTGAGAGIGLAIAERLAAEGAAVLC MUL_2885|M.ulcerans_Agy99 MRYPD-------------LAGKATIVTGAGAGIGLAIAERLAAEGAAVLC Mvan_3999|M.vanbaalenii_PYR-1 MTYPD-------------LADKAVIVTGAAAGIGLAIAERLAAERCRVVC MAV_5088|M.avium_104 MAESL-------------LLGKVAVVTGAGQGIGREIARALHRHGARVVL Mflv_4505|M.gilvum_PYR-GCK MTGR--------------LAGKVALISGAARGMGASHARVMAGHGAKVVC MAB_4680c|M.abscessus_ATCC_199 MNGNSAL-----------LQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI TH_4254|M.thermoresistible__bu MTAGSTR-----------LAGKVVLVTGAGGGLGTAIARRLADEGARLVL MSMEG_3607|M.smegmatis_MC2_155 MTQAQELSVDFDFR----LDGKVALVTGAASGIGAAIASAYATKGARIAA MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV * : .: :::*. *:* : . : Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIG-CGA--AACRVDVSDEQQIIAMVDACVAAFGGVD Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIG-CGA--AACRVDVSDEQQIIAMVDACVAAFGGVD MMAR_2869|M.marinum_M ADIDGASAEQAAAKIG-SGA--VGYQVDVSAEEQVAGMVEACVTSFGGLD MUL_2885|M.ulcerans_Agy99 ADIDGASAEQAAAKIG-SGA--VGYQVDVSAEEQVAGMVEACVTSFGGLD Mvan_3999|M.vanbaalenii_PYR-1 ADIDGAAADAAAAAIG-NGA--VGYAVDVSDEPQVVGMVEACVAAFGGVD MAV_5088|M.avium_104 ADLDGSAARSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGGLD Mflv_4505|M.gilvum_PYR-GCK GDILDSDGEAVAAELGDAARYVH---LDVTSPDDWDRAVAAAVADFGGLD MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQLAAELGDAARFTH---LDVTDAEQWRELIDTTLAGFGTIT TH_4254|M.thermoresistible__bu ADLQESQCAALADELPAPAGAHHPLGFDVADETAWISAISTVSAQYGALH MSMEG_3607|M.smegmatis_MC2_155 VDLNAEGAEALAAQLGGDRGAHRGFACDVADAASVQAAADAVAAEFGRID MLBr_01807|M.leprae_Br4923 THRASVVP-----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVE . **: * : Mb1976|M.bovis_AF2122/97 KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG Rv1941|M.tuberculosis_H37Rv KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG MMAR_2869|M.marinum_M KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG MUL_2885|M.ulcerans_Agy99 KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG Mvan_3999|M.vanbaalenii_PYR-1 KLVANAGVVHFAPLTETTVDDFDRIIGINLRGAWLCTKHAAPRMAERGGG MAV_5088|M.avium_104 VFVNNAGITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRERKTG Mflv_4505|M.gilvum_PYR-GCK VLVNNAGILNIGTVEDYELSEWHRILDVNLTGVFLGIRAATPTMKAAGRG MAB_4680c|M.abscessus_ATCC_199 GLVNNAGISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGCG TH_4254|M.thermoresistible__bu ALVNNAAIGALGNVAEERLERWDRILDVGATGVWLGMKHAVPLIRRSGGG MSMEG_3607|M.smegmatis_MC2_155 ILVNSAGVARLAPAEELSLQDWDSTLAINLSGTFLMCQAVGKRMLEAGGG MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG :* .*.: : : : *.: : . : * Mb1976|M.bovis_AF2122/97 AIVNLSSLAGQVA-VGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLL Rv1941|M.tuberculosis_H37Rv AIVNLSSLAGQVA-VGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLL MMAR_2869|M.marinum_M AIVNMSSLAGHIG-VGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALL MUL_2885|M.ulcerans_Agy99 AIVNMSSLAGHIG-VGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALL Mvan_3999|M.vanbaalenii_PYR-1 AIVNMSSLGGLVA-AAGTAAYGMSKAGIIHLSRITAAEMRSANIRSNALL MAV_5088|M.avium_104 SIVNMSSLSGKAG-NPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQ Mflv_4505|M.gilvum_PYR-GCK SIINIASIEGMAG-TVGCHGYTATKFAVRGLTKSTALELGPFGIRVNSVH MAB_4680c|M.abscessus_ATCC_199 SIVNISSAAGLVG-LALTSGYGASKWGVRGLSKVAAIELGRERIRVNSVH TH_4254|M.thermoresistible__bu SVVNICSIFGTVGGFGDSAAYHAAKGAVRTLTKNAALHWAPDGVRVNSLH MSMEG_3607|M.smegmatis_MC2_155 AIVNMASQAATVA-LDQHVAYCASKFGVVGVSKVLAAEWGGRGVRVNTIS MLBr_01807|M.leprae_Br4923 RYIFMGSVVGLSG-VPGQANYAASKSGLIGMARSLARELGSRSITANVVA : : * . . * :* .: ::: * . : * : Mb1976|M.bovis_AF2122/97 PAFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLL Rv1941|M.tuberculosis_H37Rv PAFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLL MMAR_2869|M.marinum_M PAFVDTPMQQSAMAMFDEALGTGGANTMIARLQGRMARPEEMASIVAFLL MUL_2885|M.ulcerans_Agy99 PAFVDTPMQQSAMAMFDEVLGTGGANTMIARLQGRMARPEEMARIVAFLL Mvan_3999|M.vanbaalenii_PYR-1 PAFVDTPMQQTAMTMFDEALGDGGAATMIGRLQGRMAGPAEMAGVVAFLL MAV_5088|M.avium_104 PGLIRTPMTA---AMPPDVFAEREAAVPMKRAG----EPEEVAGAVVFLA Mflv_4505|M.gilvum_PYR-GCK PGLVKTPMADWV------------PEDIFQSALGRIAQPHEVSNLVVYLA MAB_4680c|M.abscessus_ATCC_199 PGVIYTPMTAKEGF--R-----EGEGNMPIAAMGRVGNADEVAGAVAYLL TH_4254|M.thermoresistible__bu PGFIETPQLRELYKGTE-----RYERMLAGTPLGRLGRPDEIAAVVAFLV MSMEG_3607|M.smegmatis_MC2_155 PTVVLTELGHKAWDG-P-----RGDALKKLIPTGRFAYPDEIAAAAVFLA MLBr_01807|M.leprae_Br4923 PGFIDTEMTRAMDSKYQ-------EAALQAIPLGRIGAVEEIAGAVSFLA * .: * *:: . :* Mb1976|M.bovis_AF2122/97 SDDASMITGTTQIADGGTIAALW----------------- Rv1941|M.tuberculosis_H37Rv SDDASMITGTTQIADGGTIAALW----------------- MMAR_2869|M.marinum_M SDDSSMITGTTQIADGGTIAALW----------------- MUL_2885|M.ulcerans_Agy99 PDDSSMITGTTQIADGGTIAALW----------------- Mvan_3999|M.vanbaalenii_PYR-1 SDAASMVNGTAQLADGGTLAALW----------------- MAV_5088|M.avium_104 SELSSYITGTVLGVGGGRYM-------------------- Mflv_4505|M.gilvum_PYR-GCK SDESSYSTGAEFVVDGGTLAGLAHKDFSAVDVDQQPEWIT MAB_4680c|M.abscessus_ATCC_199 SDAASYVTGAELAVDGGWTAGPTLTTITGQ---------- TH_4254|M.thermoresistible__bu SDDASFITGSEVYADGGWTAR------------------- MSMEG_3607|M.smegmatis_MC2_155 SDAAAMINGADLVIDGGYTIK------------------- MLBr_01807|M.leprae_Br4923 SEDAGYISGAVIPVDGGLGMGH------------------ .: :. .*: .**