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TDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAVTHRASVVPDWFFGVECDVTDN DAIGAAFKAVEEHQGPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRY IFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTRAMDSKYQEAALQA IPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01807 | fabG1 | - | 100% (253) | 3-oxoacyl- |
| M. leprae Br4923 | MLBr_02565 | fabG | 8e-30 | 34.18% (237) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01740 | - | 3e-14 | 26.13% (199) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1519 | fabG1 | 3e-94 | 69.75% (238) | 3-oxoacyl- |
| M. gilvum PYR-GCK | Mflv_3658 | - | 6e-96 | 70.29% (239) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. tuberculosis H37Rv | Rv1483 | fabG1 | 3e-94 | 69.75% (238) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2723c | - | 1e-100 | 76.60% (235) | 3-oxoacyl- |
| M. marinum M | MMAR_2289 | fabG1 | 2e-98 | 69.92% (256) | 3-oxoacyl- |
| M. avium 104 | MAV_3295 | fabG | 6e-95 | 66.27% (255) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_3150 | fabG | 2e-96 | 67.98% (253) | 3-oxoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3966 | - | 1e-68 | 68.13% (182) | PUTATIVE 3-oxoacyl-[acyl-carrier-protein] reductase |
| M. ulcerans Agy99 | MUL_1491 | fabG1 | 4e-98 | 69.53% (256) | 3-oxoacyl- |
| M. vanbaalenii PYR-1 | Mvan_2752 | - | 6e-97 | 66.80% (253) | 3-oxoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_3658|M.gilvum_PYR-GCK MTSTEN---TAGESVAGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
Mvan_2752|M.vanbaalenii_PYR-1 MTLTENSAGTAGETGGGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
MAV_3295|M.avium_104 MTDTATENTTESAADFGRPAFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
MSMEG_3150|M.smegmatis_MC2_155 MTVTDNPADTAGEATAGRPAFVSRSVLVTGGNRGIGLAIARRLAADGHKV
TH_3966|M.thermoresistible__bu --------VSPEAASPVQASHCSCAIRVSAAN------------------
Mb1519|M.bovis_AF2122/97 MTATATEG--------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
Rv1483|M.tuberculosis_H37Rv MTATATEG--------AKPPFVSRSVLVTGGNRGIGLAIAQRLAADGHKV
MMAR_2289|M.marinum_M MTDTATEQNTESAADGGKPAFVSRSVLVTGGNRGIGLAIAQRLAADGHRV
MUL_1491|M.ulcerans_Agy99 MTDTATEQNTESAADGGKPAFVSRSVLVTGGNRGIGLAIAQRLATDGHRV
MLBr_01807|M.leprae_Br4923 --MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRV
MAB_2723c|M.abscessus_ATCC_199 --MTNA-------------EFVPRSVLVTGGNRGIGLAVAQRLAADGHKV
. . :: *:..*
Mflv_3658|M.gilvum_PYR-GCK AVTHRGSGAPDGLFGVVCDVTDNDAVDRAFKEVEEHQGPVEVLVSNAGIS
Mvan_2752|M.vanbaalenii_PYR-1 AVTHRGSGAPEGLFGVECDVTDNEAVDRAFAEVEEHQGPVEVLVSNAGIS
MAV_3295|M.avium_104 AVTHRGSGAPDGLFGVECDVTDNDAVDRAFTEVEEHQGPVEVLVSNAGIS
MSMEG_3150|M.smegmatis_MC2_155 AVTHRGSGAPDDLFGVQCDVTDSAAVDRAFKEVEEHQGPVEVLVANAGIS
TH_3966|M.thermoresistible__bu ---------PXX----------XESVDRAFKAVEEHQGPVEVLVANAGIS
Mb1519|M.bovis_AF2122/97 AVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLS
Rv1483|M.tuberculosis_H37Rv AVTHRGSGAPKGLFGVECDVTDSDAVDRAFTAVEEHQGPVEVLVSNAGLS
MMAR_2289|M.marinum_M AVTHRGSGAPEGLFGVECDVTDNDAVDRAFKEVEEHQGPVEVLVSNAGLS
MUL_1491|M.ulcerans_Agy99 AVTHRGSGAPEGLFGVECDVTDNDAVDRAFKEVEEHQGPVEVLVSNAGLS
MLBr_01807|M.leprae_Br4923 AVTHRASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVEVLVANAGIT
MAB_2723c|M.abscessus_ATCC_199 AVTHRGSGAPEGLLGVQCDITDNDQIDAAFKEVEEKQGPVEVLVANAGIT
* :. ** ***:********:***::
Mflv_3658|M.gilvum_PYR-GCK KDAFLMRMTEDRFTDVIDANLTGAFRVAQRASRSMQRKRFGRIIFIGSVS
Mvan_2752|M.vanbaalenii_PYR-1 KDAFLMRMTEERFEEVINANLTGAFRVAQRASRSMQRKRFGRIIFIGSVS
MAV_3295|M.avium_104 KDAFLIRMTEERFTEVINANLTGAFRVTQRAARSMQKKRFGRIIYIGSVS
MSMEG_3150|M.smegmatis_MC2_155 KDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKRFGRIIFIGSVS
TH_3966|M.thermoresistible__bu KDAFLMRMTEERFTEVIDTNLTGAFRVVQRASRTMQRKRFGRIILMGSVS
Mb1519|M.bovis_AF2122/97 ADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVS
Rv1483|M.tuberculosis_H37Rv ADAFLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKFGRMIFIGSVS
MMAR_2289|M.marinum_M ADAFLIRMTEERFEKVIDANLTGAFRVAQRASRSMQRKKFGRLIFIGSVS
MUL_1491|M.ulcerans_Agy99 ADAFLIRMTEERFEKVIDANLTGAFRVAQRASRSMQRKKFGRLIFIGSVS
MLBr_01807|M.leprae_Br4923 SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFGRYIFMGSVV
MAB_2723c|M.abscessus_ATCC_199 ADMLIMRMSEEQFLKVIDANLIGTFRLAKRASRNMIKKRFGRLIFMGSVA
* :::**:*::* .**:.** *.** .: *:*.* :::*** * :***
Mflv_3658|M.gilvum_PYR-GCK GMWGIGNQANYAAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTR
Mvan_2752|M.vanbaalenii_PYR-1 GMWGIGNQANYAAAKAGLIGMARSISRELSKANVTANVVAPGYIDTEMTR
MAV_3295|M.avium_104 GMWGIGNQSNYAAAKAGLIGMARSISRELSKAGVTANVVAPGYIDTEMTR
MSMEG_3150|M.smegmatis_MC2_155 GMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYIDTEMTR
TH_3966|M.thermoresistible__bu GTWGIGNQANYAAAKAGLIGMARSISRELSKANVTANVVAPGYIDTEMTR
Mb1519|M.bovis_AF2122/97 GSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTR
Rv1483|M.tuberculosis_H37Rv GSWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYIDTDMTR
MMAR_2289|M.marinum_M GSWGIGNQANYAASKAGVIGMARSIARELSKVNVTANVVAPGYIDTDMTR
MUL_1491|M.ulcerans_Agy99 GSWGIGNQANYAASKAGVIGMARSIARELSKVNVTANVVAPGYIDTDMTR
MLBr_01807|M.leprae_Br4923 GLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAPGFIDTEMTR
MAB_2723c|M.abscessus_ATCC_199 GQIGLPGQANYSASKAGLVGMARALTRELGSRSITANVVAPGFIDTDMTR
* *: .*:**:*:*:*::****:::***.. .:********:***:***
Mflv_3658|M.gilvum_PYR-GCK ALDERIQAGALEFIPAKRVGTADEVAGAVSFLASEDASYIAGAVIPVDGG
Mvan_2752|M.vanbaalenii_PYR-1 ALDERIQAGALEFIPAKRVGTADEVAGAVSFLASEDASYIAGAVIPVDGG
MAV_3295|M.avium_104 ALDERIQAGALEFIPAKRVGTAAEVAGAVSFLASEDASYIAGAVIPVDGG
MSMEG_3150|M.smegmatis_MC2_155 ALDERIQAGALDFIPAKRVGTAEEVAGAVSFLASEDASYIAGAVIPVDGG
TH_3966|M.thermoresistible__bu ALDERIQQGALDFIPAKRVGTAEEVAGVVSFLASEDAGYIAGAVIPVDGG
Mb1519|M.bovis_AF2122/97 ALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGG
Rv1483|M.tuberculosis_H37Rv ALDERIQQGALQFIPAKRVGTPAEVAGVVSFLASEDASYISGAVIPVDGG
MMAR_2289|M.marinum_M ALDERIQEGALQFIPAKRVGTAAEVAGVVSFLASEDASYISGAVIPVDGG
MUL_1491|M.ulcerans_Agy99 ALDERIQEGALQFIPAKRVGTAAEVAGVVSFLASEDASYISGAVIPVDGG
MLBr_01807|M.leprae_Br4923 AMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDAGYISGAVIPVDGG
MAB_2723c|M.abscessus_ATCC_199 ELGEKHVETALTAIPMGRIGEPSEVAGVVSWLASPDAAYVSGAVIPVDGG
:..: ** ** *:* *:**.**:*** **.*::*********
Mflv_3658|M.gilvum_PYR-GCK MGMGH
Mvan_2752|M.vanbaalenii_PYR-1 MGMGH
MAV_3295|M.avium_104 MGMGH
MSMEG_3150|M.smegmatis_MC2_155 MGMGH
TH_3966|M.thermoresistible__bu MGMGH
Mb1519|M.bovis_AF2122/97 MGMGH
Rv1483|M.tuberculosis_H37Rv MGMGH
MMAR_2289|M.marinum_M MGMGH
MUL_1491|M.ulcerans_Agy99 MGMGH
MLBr_01807|M.leprae_Br4923 LGMGH
MAB_2723c|M.abscessus_ATCC_199 LGMGH
:****