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FDDPRALFDIAGKSAIVIGATGSLGQIASRALAGAGANVAICGSREDALSDLRDELAAAPGCIVPIARRP DSESASDAIVKETIEAFGGVDILVVASGVNEVAPAVDMQPARFEAVLDANVTSTWLAVRSAGRAMIERGR GGKIILTSSARGKLGHPAGYTAYCASKAAVDGLVRSFGCEWGRYGITVNGLAPTVFRSPLTSWMFTDEPA AQATRENFLSRIPLGRLGEPEDLAGPILFLSAPASDFLTGHVVYPDGGYTAG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4490c | - | - | 100% (263) | oxidoreductase |
| M. abscessus ATCC 19977 | MAB_0598 | - | 8e-29 | 32.93% (246) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_3844c | - | 1e-25 | 32.84% (271) | putative short-chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1741 | - | 4e-68 | 48.83% (256) | oxidoreductase |
| M. gilvum PYR-GCK | Mflv_0305 | - | 2e-29 | 33.33% (255) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1714 | - | 5e-68 | 48.83% (256) | oxidoreductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-21 | 28.80% (250) | 3-oxoacyl- |
| M. marinum M | MMAR_2849 | - | 1e-38 | 36.08% (255) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2775 | - | 6e-40 | 37.50% (256) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4117 | - | 3e-34 | 36.25% (251) | 2-deoxy-D-gluconate 3-dehydrogenase |
| M. thermoresistible (build 8) | TH_3791 | - | 4e-31 | 35.55% (256) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3898 | fabG | 2e-26 | 31.43% (245) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_0894 | - | 7e-36 | 34.88% (258) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1741|M.bovis_AF2122/97 --MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGAR
Rv1714|M.tuberculosis_H37Rv --MEEMALAQQVPNLGLARFSVQDKSILITGATGSLGRVAARALADAGAR
MAB_4490c|M.abscessus_ATCC_199 --------MFDDP---RALFDIAGKSAIVIGATGSLGQIASRALAGAGAN
TH_3791|M.thermoresistible__bu MTANTG------ASVLD-MFRLTGRSAIVTGASSGLGRGFAQTLAAAGAT
Mvan_0894|M.vanbaalenii_PYR-1 MTVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALALRSAGAE
MSMEG_4117|M.smegmatis_MC2_155 MT-----------PRPE---NLEGKVAIVTGAGRGLGRAMAKGLVDAGAA
MMAR_2849|M.marinum_M -------------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQ
MAV_2775|M.avium_104 ---------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGAR
MLBr_01807|M.leprae_Br4923 ---MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR
MUL_3898|M.ulcerans_Agy99 ---------MCGAHRDRG-----YVYPVVTGGAQGLGLAIAERFVSEGAR
Mflv_0305|M.gilvum_PYR-GCK -----MTTTSANPFDLTG------HVAVVTGGGSGIGLGMAGGLARAGAT
:: *. .:* : *
Mb1741|M.bovis_AF2122/97 LTLAGGNSAGLAELVNGAGIDDAAVV---TCRPDSLADAQQMVEAALGRY
Rv1714|M.tuberculosis_H37Rv LTLAGGNSAGLAELVNGAGIDDAAVV---TCRPDSLADAQQMVEAALGRY
MAB_4490c|M.abscessus_ATCC_199 VAICGSREDALSDLRDELAAAPGCIVP-IARRPDSESASDAIVKETIEAF
TH_3791|M.thermoresistible__bu VYAAARRTDRLETLAAENPAIR----A-VTCDVTDEQDRRALVERVVAET
Mvan_0894|M.vanbaalenii_PYR-1 VVVAARRADRLAELCEAHEGLS----A-VSCDVADPASIESAYQCVEERV
MSMEG_4117|M.smegmatis_MC2_155 VTVAARTSAELESFVADAKAAGGQALA-CSTDITDEASVERLVDATVETF
MMAR_2849|M.marinum_M VAVAARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGEL
MAV_2775|M.avium_104 VAIAARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAEL
MLBr_01807|M.leprae_Br4923 VAVTHR----ASVVPDWFFG--------VECDVTDNDAIGAAFKAVEEHQ
MUL_3898|M.ulcerans_Agy99 VVLGDVNLE-ATEAAAKQLGGGEVAVA-VRCDVTKADEVETLLQAALERF
Mflv_0305|M.gilvum_PYR-GCK VAILGRNAQRLDDAAATLRTHGNPVLP-LVCDVTDEEAVTETMARIRDEF
: .
Mb1741|M.bovis_AF2122/97 GRLDGVLVASGSN-HVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLL
Rv1714|M.tuberculosis_H37Rv GRLDGVLVASGSN-HVAPITEMAVEDFDAVMDANVRGAWLVCRAAGRVLL
MAB_4490c|M.abscessus_ATCC_199 GGVDILVVASGVN-EVAPAVDMQPARFEAVLDANVTSTWLAVRSAGRAMI
TH_3791|M.thermoresistible__bu GGVDVLVNNAGKP-GGPDAVKESADEFASILDLNLAAGFHLSCDVVRANP
Mvan_0894|M.vanbaalenii_PYR-1 GAVDILVNNAGTS-IPARAEDESLTDFQYVLDVNLVGAFRLTQLVGRKMI
MSMEG_4117|M.smegmatis_MC2_155 GRVDILVNNSGIV-ATTPLIEQSADEWDRVVATNLRGTFLATRAVGRHLV
MMAR_2849|M.marinum_M GGIDIAVCNAGIV-SVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMV
MAV_2775|M.avium_104 GGIDIAVCNAGII-SVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMV
MLBr_01807|M.leprae_Br4923 GPVEVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMI
MUL_3898|M.ulcerans_Agy99 GGLDIMVNNAGIT-RDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMR
Mflv_0305|M.gilvum_PYR-GCK GWLDSCFANAGVRGRFTPVLETSLAEFRSVTSVDLDGVFLTLREAARQMV
* :: . :* : : .: . : .
Mb1741|M.bovis_AF2122/97 EQGQG-GSVVLVSSVRGGLGNAAGYSAYCPSKAGTDLLAKTLAAEWGGHG
Rv1714|M.tuberculosis_H37Rv EQGQG-GSVVLVSSVRGGLGNAAGYSAYCPSKAGTDLLAKTLAAEWGGHG
MAB_4490c|M.abscessus_ATCC_199 ERGRG-GKIILTSSARGKLGHPAGYTAYCASKAAVDGLVRSFGCEWGRYG
TH_3791|M.thermoresistible__bu ENHRL-SIVNVSSVIGLVSTAPIGGAGYAASKAGVLGLTRELAGQWGRQG
Mvan_0894|M.vanbaalenii_PYR-1 ERGEG-SIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQWARYN
MSMEG_4117|M.smegmatis_MC2_155 AQRSG-KVINIASNFALQGVAN--HAAYSASKAGVIAFTRSMAIEWARDN
MMAR_2849|M.marinum_M DQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQ
MAV_2775|M.avium_104 RQGRGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHD
MLBr_01807|M.leprae_Br4923 KQ-RFGRYIFMGSVVG--LSGVPGQANYAASKSGLIGMARSLARELGSRS
MUL_3898|M.ulcerans_Agy99 EN-KRGAIVNMSSVSG--KVGMVGQTNYSAAKAGIVGMTKAAAKELAHVG
Mflv_0305|M.gilvum_PYR-GCK AAGRGGSLVGVSSLGA--FQGMPRQPAYAASKAGVTSMMDSFAVELARHG
: * *..:*.. : . : .
Mb1741|M.bovis_AF2122/97 IRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPEDFVG
Rv1714|M.tuberculosis_H37Rv IRVNALAPTVFRSAVTEWMFTDDPKGRATREAMLARIPLRRFAEPEDFVG
MAB_4490c|M.abscessus_ATCC_199 ITVNGLAPTVFRSPLTSWMFTDEPAAQATRENFLSRIPLGRLGEPEDLAG
TH_3791|M.thermoresistible__bu IRVNALVPGWFDTEMTDGLFTNERSATWVRR----NTMLNRGGREGEVDG
Mvan_0894|M.vanbaalenii_PYR-1 VRVNALAPGFFPSELTTELLDDDAGGAYIRR----NTPMARAGRAGELSG
MSMEG_4117|M.smegmatis_MC2_155 IQVNAIAPGYFATSLNADMRADADMAAKVVR----AIPARRMGEPEELTS
MMAR_2849|M.marinum_M IRVNSVSPGYIRTELVEPLADYHALWEPKIP-------LGRMGRPEELTG
MAV_2775|M.avium_104 IRVNSVSPGYIRTELVEPLHEYHRQWQPKIP-------LGRMGRPDELAG
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTEMTRA--MDSKYQEAALQ----AIPLGRIGAVEEIA-
MUL_3898|M.ulcerans_Agy99 VRVNAIAPGLIRSAMTEA--MPQRIWDQKLA----EVPMGRAGEPSEVA-
Mflv_0305|M.gilvum_PYR-GCK IRANTVAPGWFETEMTSEGMADERFTSRVLP----RVPVRRWGAAEDVAG
: .* : * : : : * . :.
Mb1741|M.bovis_AF2122/97 --ALIYLLSDASSFYTGQVMYLDGGYTAC-
Rv1714|M.tuberculosis_H37Rv --ALIYLLSDASSFYTGQVMYLDGGYTAC-
MAB_4490c|M.abscessus_ATCC_199 --PILFLSAPASDFLTGHVVYPDGGYTAG-
TH_3791|M.thermoresistible__bu --ALLFLASDASSYVTGQAIVVDGGWTAR-
Mvan_0894|M.vanbaalenii_PYR-1 --ALLLLASGAGSFITGQVIAVDGGWTAR-
MSMEG_4117|M.smegmatis_MC2_155 --WLLLLAGSASDFMTGEVIVIDGGQSVR-
MMAR_2849|M.marinum_M --LYLYLASAASSYMTGSDIVIDGGYTCP-
MAV_2775|M.avium_104 --IYLYLASAASSYMTGSDIVIDGGYSCP-
MLBr_01807|M.leprae_Br4923 -GAVSFLASEDAGYISGAVIPVDGGLGMGH
MUL_3898|M.ulcerans_Agy99 -SVALFLACDLSSYMTGTVLDVTGGRFI--
Mflv_0305|M.gilvum_PYR-GCK VGVAVYLAGPASAYHTGDVLRLDGGYLKF-
* . : :* : **