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M. thermoresistible (build 8) TH_2623 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 1281026 - 1281787
length: 254

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_2623--100% (254)short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_3791-4e-4846.46% (254) PUTATIVE putative short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)TH_4266-1e-4641.43% (251) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1963c-3e-4338.82% (255) short chain dehydrogenase
M. gilvum PYR-GCKMflv_1263-9e-4741.90% (253) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1928c-3e-4338.82% (255) short chain dehydrogenase
M. leprae Br4923MLBr_01807fabG13e-2733.33% (246) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4913c-3e-4441.94% (248) putative short chain dehydrogenase/reductase
M. marinum MMMAR_2849-2e-4138.91% (257) short-chain type dehydrogenase/reductase
M. avium 104MAV_1391-2e-5348.02% (252) short-chain dehydrogenase/reductase SDR
M. smegmatis MC2 155MSMEG_6626-4e-4842.06% (252) short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_4442-3e-3839.45% (256) short chain dehydrogenase
M. vanbaalenii PYR-1Mvan_0894-1e-4645.06% (253) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1963c|M.bovis_AF2122/97           -------------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQ
Rv1928c|M.tuberculosis_H37Rv        -------------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQ
MMAR_2849|M.marinum_M               -------------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQ
Mflv_1263|M.gilvum_PYR-GCK          ---------------MSDRFSMEGRVAVITGGGTGIGRASALVLAEHGAD
MSMEG_6626|M.smegmatis_MC2_155      --------------MAVSRFSLEGRVAVITGGGTGIGRASALVLAEHGAD
MAV_1391|M.avium_104                ---------------MSDRFALTDRVAVITGAGTGIGRASALVLAEHGAD
MAB_4913c|M.abscessus_ATCC_199      --------------------MLQDKVVVVTGGSRGLGRAMVRAFAAHGAD
MUL_4442|M.ulcerans_Agy99           --------------MILDRFRLDDQVAVITGGGRGFGAAIALAFAEAGAD
TH_2623|M.thermoresistible__bu      -------------MGVLDKFRLDDKVVIVTGASSGLGVAFARACAEAGAD
Mvan_0894|M.vanbaalenii_PYR-1       MTVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALALRSAGAE
MLBr_01807|M.leprae_Br4923          ---MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR
                                                         : .:  ::**.. *:*   .      *  

Mb1963c|M.bovis_AF2122/97           VAIAARHLDALEKLADEIGTS-GGKVVPVCCDVSQHQQVTSMLDQVTAEL
Rv1928c|M.tuberculosis_H37Rv        VAIAARHLDALEKLADEIGTS-GGKVVPVCCDVSQHQQVTSMLDQVTAEL
MMAR_2849|M.marinum_M               VAVAARHSDALQVVADEIAGV-GGKALPIRCDVTQPDQVRGMLDQMTGEL
Mflv_1263|M.gilvum_PYR-GCK          VVLAGRRAEPLKETAAEVEAL-GRRALAVPTDVTDADACQALVDTTLAEF
MSMEG_6626|M.smegmatis_MC2_155      IVLAGRRLEPLKNTATEIEAL-GRRALAVPTDVTDPEACRSLVDATVDEF
MAV_1391|M.avium_104                IVLAGRRPDPLQATAKEVEAL-GRRSLIVPTDVTETQQCQHLVDATMAEF
MAB_4913c|M.abscessus_ATCC_199      VVIASRKIDSCQELAAQVEAEHGRRALPVACNVSSWEQCDHLVDTVYREF
MUL_4442|M.ulcerans_Agy99           VVIASRTQSQLDEVADTVRSI-GRRAHVVAADLAHPEATAELAGQAVEAF
TH_2623|M.thermoresistible__bu      VVLAARRVERLQQTAEQVRAT-GRRALTVATDVVDPQQCQEMVDAAMTEF
Mvan_0894|M.vanbaalenii_PYR-1       VVVAARRADRLAELCEAHEGL-----SAVSCDVADPASIESAYQCVEERV
MLBr_01807|M.leprae_Br4923          VAVTHR------------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQ
                                    :.:: *                      :  ::                 

Mb1963c|M.bovis_AF2122/97           GGIDIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMV
Rv1928c|M.tuberculosis_H37Rv        GGIDIAVCNAGII-TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMV
MMAR_2849|M.marinum_M               GGIDIAVCNAGIV-SVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMV
Mflv_1263|M.gilvum_PYR-GCK          GRLDVLLNNAGGG-ETKSLMKWTDDEWHHVLDLNLSSAWYLSRAAAKPMI
MSMEG_6626|M.smegmatis_MC2_155      GRLDILLNNAGGG-ETKSLMKWTDDEWRQVLDLNLSSAWYLSRAAVKPML
MAV_1391|M.avium_104                GRLDILVNNAGGG-ETKGITRWTEEEWHDVVDLNLGSVWFLSRCAVKPMM
MAB_4913c|M.abscessus_ATCC_199      GRVDVLVNNAGLSPLYPSLDQVSEALFDKVIGVNLKGPFRLSASIATKMA
MUL_4442|M.ulcerans_Agy99           GRLDIVVNNVGGT-MPNTLLTTSTKDLKDAFTFNVATAHALTVAAVPLML
TH_2623|M.thermoresistible__bu      GRVDVLVNNAGVG-TAVPATRETPEEFRTVIDINLNGSYWAAQACGRVMR
Mvan_0894|M.vanbaalenii_PYR-1       GAVDILVNNAGTS-IPARAEDESLTDFQYVLDVNLVGAFRLTQLVGRKMI
MLBr_01807|M.leprae_Br4923          GPVEVLVANAGIT-SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMI
                                    * ::: : *.*           .          *:      :      * 

Mb1963c|M.bovis_AF2122/97           KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAP-H
Rv1928c|M.tuberculosis_H37Rv        KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAP-H
MMAR_2849|M.marinum_M               DQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAP-H
Mflv_1263|M.gilvum_PYR-GCK          AQ-GSGAIVNISSGAG-LLAMPQ-APIYGAAKAGLQNLTGSMAAAWTR-K
MSMEG_6626|M.smegmatis_MC2_155      SQ-GKGSIVNISSGAS-LLAMPQ-AAIYGAAKAGLNNLTGSMAAAWTR-K
MAV_1391|M.avium_104                TQ-GSGAIVNISSGAS-LIAMPQ-AAIYAAAKAGVNNLTGSMAAAWGR-K
MAB_4913c|M.abscessus_ATCC_199      AG-AGGSIINISSIEA-VRPDAT-ALPYAAAKAGLNALTLGLSHTFG--P
MUL_4442|M.ulcerans_Agy99           EHSGGGGIINITSTMG-RVAGRG-FAAYGTAKVALAHYTR-LAALDLC-P
TH_2623|M.thermoresistible__bu      PG---SSIVNISSILG-ITTASLPQAAYSASKAGVIGLTRDLAQQWTPRK
Mvan_0894|M.vanbaalenii_PYR-1       ER-GEGSIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQWAR-Y
MLBr_01807|M.leprae_Br4923          KQ-RFGRYIFMGSVVG--LSGVPGQANYAASKSGLIGMARSLARELGS-R
                                         .  :   *  .           * ::* .:   :  ::       

Mb1963c|M.bovis_AF2122/97           KIRVNSVSPGYILTELVEPYT---EYQPLWEPKIP-LGRLGRPEELAGLY
Rv1928c|M.tuberculosis_H37Rv        KIRVNSVSPGYILTELVEPYT---EYQPLWEPKIP-LGRLGRPEELAGLY
MMAR_2849|M.marinum_M               QIRVNSVSPGYIRTELVEPLA---DYHALWEPKIP-LGRMGRPEELTGLY
Mflv_1263|M.gilvum_PYR-GCK          GVRVNCIACGAVRTPGLEADAKRQGFDIDMIGQTNGSGRIAEPDEIGYGV
MSMEG_6626|M.smegmatis_MC2_155      GVRVNCIACGAIRTPGLEADAARQGFDIDMIGQTNGSGRIAEPDEIGYGV
MAV_1391|M.avium_104                GIRVNCIACGAIRTDGLLADAAKGGFDVDQLGAMNAMGRIAEPDEIGYGV
MAB_4913c|M.abscessus_ATCC_199      TVRTNTIQCGLFNTD--IAAAWPEGFAEALIPSIP-LRRVGEPEDIVGAA
MUL_4442|M.ulcerans_Agy99           RIRVNAIAPGSILTSALEVVAANDELRAPMEQATP-LRRLGDPVDIAAAA
TH_2623|M.thermoresistible__bu      GIRVNAIAPGFFKSE--MTDQYKPGYLDSQMPRVL-MGRTGDPEELAATL
Mvan_0894|M.vanbaalenii_PYR-1       NVRVNALAPGFFPSELTTELLDDDAGGAYIRRNTP-MARAGRAGELSGAL
MLBr_01807|M.leprae_Br4923          SITANVVAPGFIDTEMTRAMDS--KYQEAALQAIP-LGRIGAVEEIAGAV
                                     : .* :  * . :                        * .   ::    

Mb1963c|M.bovis_AF2122/97           LYLASEASSYMTGSDIVIDGGYTCP---------
Rv1928c|M.tuberculosis_H37Rv        LYLASEASSYMTGSDIVIDGGYTCP---------
MMAR_2849|M.marinum_M               LYLASAASSYMTGSDIVIDGGYTCP---------
Mflv_1263|M.gilvum_PYR-GCK          LFFASDASSYCSGQTLYMHGGPGPAGV-------
MSMEG_6626|M.smegmatis_MC2_155      LFFASDASSYCSGQTLYMHGGPGPAGV-------
MAV_1391|M.avium_104                LFFASDASSYCSGQTLYIHGGPGPAGI-------
MAB_4913c|M.abscessus_ATCC_199      LYLASEASAYCTGTTIRLDGGIL-----------
MUL_4442|M.ulcerans_Agy99           VYLASPAGSFLTGKTLEVDGGLTHPNLDIPVPDL
TH_2623|M.thermoresistible__bu      VWLVSDAGGYVTGQTIVVDGGITIT---------
Mvan_0894|M.vanbaalenii_PYR-1       LLLASGAGSFITGQVIAVDGGWTAR---------
MLBr_01807|M.leprae_Br4923          SFLASEDAGYISGAVIPVDGGLGMGH--------
                                      :.*  ..: :*  : :.**