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SVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQVAVAARHSDALQVVADEIAGVGGKALPIRCDVTQ PDQVRGMLDQMTGELGGIDIAVCNAGIVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMVDQGLGG TIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQIRVNSVSPGYIRTELVEPLADYHALW EPKIPLGRMGRPEELTGLYLYLASAASSYMTGSDIVIDGGYTCP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_2849 | - | - | 100% (255) | short-chain type dehydrogenase/reductase |
| M. marinum M | MMAR_2981 | fabG3_1 | 2e-38 | 40.73% (248) | 20-beta-hydroxysteroid dehydrogenase FabG3_1 |
| M. marinum M | MMAR_4033 | fabG | 1e-36 | 34.96% (246) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 1e-118 | 81.96% (255) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1825 | - | 5e-40 | 36.72% (256) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1928c | - | 1e-118 | 81.96% (255) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 2e-31 | 35.42% (240) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4490c | - | 8e-39 | 36.08% (255) | oxidoreductase |
| M. avium 104 | MAV_2775 | - | 1e-113 | 79.13% (254) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3604 | - | 7e-43 | 38.58% (254) | sorbitol utilization protein SOU2 |
| M. thermoresistible (build 8) | TH_2623 | - | 2e-41 | 38.91% (257) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3898 | fabG | 2e-35 | 34.58% (240) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_0894 | - | 5e-43 | 37.45% (251) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1963c|M.bovis_AF2122/97 --------MSVLDL-----------FDLHGKRALITGASTGIGKRVALAY
Rv1928c|M.tuberculosis_H37Rv --------MSVLDL-----------FDLHGKRALITGASTGIGKRVALAY
MMAR_2849|M.marinum_M --------MSVLDL-----------FDLSGKRALITGASTGIGKKVALAY
MAV_2775|M.avium_104 ----------MLDL-----------FDLRGRRALVTGASTGIGKQVAQAY
MAB_4490c|M.abscessus_ATCC_199 ------MFDDPRAL-----------FDIAGKSAIVIGATGSLGQIASRAL
TH_2623|M.thermoresistible__bu --------MGVLDK-----------FRLDDKVVIVTGASSGLGVAFARAC
Mvan_0894|M.vanbaalenii_PYR-1 ------MTVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALAL
Mflv_1825|M.gilvum_PYR-GCK ---------MILDR-----------FRLDDQVAVVTGAGRGLGAAMALAF
MSMEG_3604|M.smegmatis_MC2_155 --------MDVRSA-----------FDLSGRTALVTGGNQGLGKAFAIAL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGK---------PAFVSRSILVTGGNRGIGLAVARRL
MUL_3898|M.ulcerans_Agy99 ------MCGAHRDRG--------------YVYPVVTGGAQGLGLAIAERF
:: *. .:* :
Mb1963c|M.bovis_AF2122/97 VEAGAQVAIAARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLD
Rv1928c|M.tuberculosis_H37Rv VEAGAQVAIAARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLD
MMAR_2849|M.marinum_M AEAGAQVAVAARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLD
MAV_2775|M.avium_104 LQAGARVAIAARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVD
MAB_4490c|M.abscessus_ATCC_199 AGAGANVAICGSREDALSDLRDELAAAP-GCIVPIARRPDSESASDAIVK
TH_2623|M.thermoresistible__bu AEAGADVVLAARRVERLQQTAEQVRATG-RRALTVATDVVDPQQCQEMVD
Mvan_0894|M.vanbaalenii_PYR-1 RSAGAEVVVAARRADRLAELCEAHEGLS-----AVSCDVADPASIESAYQ
Mflv_1825|M.gilvum_PYR-GCK AEAGADVLIAARTQSQLEAVAEQIAGTG-RRAHIVVADLARPEDTAGLAA
MSMEG_3604|M.smegmatis_MC2_155 AQAGARVSFSGRNAERNEKTAAEAAAAG-HQLHAITADITRAEDVERMTA
MLBr_01807|M.leprae_Br4923 VADGHRVAVTHR---ASVVPDWFFG---------VECDVTDNDAIGAAFK
MUL_3898|M.ulcerans_Agy99 VSEGARVVLGDVNLEATEAAAKQLGGGE--VAVAVRCDVTKADEVETLLQ
* * . :
Mb1963c|M.bovis_AF2122/97 QVTAELGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAA
Rv1928c|M.tuberculosis_H37Rv QVTAELGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAA
MMAR_2849|M.marinum_M QMTGELGGIDIAVCNAGIVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAA
MAV_2775|M.avium_104 RMIAELGGIDIAVCNAGIISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAA
MAB_4490c|M.abscessus_ATCC_199 ETIEAFGGVDILVVASGVNEVAPAVDMQPARFEAVLDANVTSTWLAVRSA
TH_2623|M.thermoresistible__bu AAMTEFGRVDVLVNNAGVGTAVPATRETPEEFRTVIDINLNGSYWAAQAC
Mvan_0894|M.vanbaalenii_PYR-1 CVEERVGAVDILVNNAGTSIPARAEDESLTDFQYVLDVNLVGAFRLTQLV
Mflv_1825|M.gilvum_PYR-GCK QAVEAFGRLDIVVNNVGGTMPNALLNTSTKDMRDAFTFNVATAHALTTAA
MSMEG_3604|M.smegmatis_MC2_155 EAIEALGHIDILVNNAGTCHHGESWTVTEEQWDDVFDLNVKALWACSLAV
MLBr_01807|M.leprae_Br4923 AVEEHQGPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLA
MUL_3898|M.ulcerans_Agy99 AALERFGGLDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLA
* ::: * * ::
Mb1963c|M.bovis_AF2122/97 AKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVE
Rv1928c|M.tuberculosis_H37Rv AKAMVKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVE
MMAR_2849|M.marinum_M ARAMVDQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVE
MAV_2775|M.avium_104 ARAMVRQGRGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVE
MAB_4490c|M.abscessus_ATCC_199 GRAMIERGRGGKIILTSSARGKLG-HPAGYTAYCASKAAVDGLVRSFGCE
TH_2623|M.thermoresistible__bu GR--VMR-PGSSIVNISSILGITTASLP-QAAYSASKAGVIGLTRDLAQQ
Mvan_0894|M.vanbaalenii_PYR-1 GRKMIER-GEGSIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQ
Mflv_1825|M.gilvum_PYR-GCK VPLMLEHSGGGSIINITSTMGRVAGRG--FAAYGTAKAALAHYTRLSALD
MSMEG_3604|M.smegmatis_MC2_155 GAHMRER-GSGSVVNIGSMSGIIVNRPQMQPAYNASKAAVHHLTKSLAAE
MLBr_01807|M.leprae_Br4923 SRNMIKQ-RFGRYIFMGSVVGLSGVPG--QANYAASKSGLIGMARSLARE
MUL_3898|M.ulcerans_Agy99 AAIMREN-KRGAIVNMSSVSGKVGMVG--QTNYSAAKAGIVGMTKAAAKE
. . : * * * ::*..: .: . :
Mb1963c|M.bovis_AF2122/97 LAPHK-IRVNSVSPGYILTELV------EPYTEYQPL-WEPKIPLGRLGR
Rv1928c|M.tuberculosis_H37Rv LAPHK-IRVNSVSPGYILTELV------EPYTEYQPL-WEPKIPLGRLGR
MMAR_2849|M.marinum_M LAPHQ-IRVNSVSPGYIRTELV------EPLADYHAL-WEPKIPLGRMGR
MAV_2775|M.avium_104 FAPHD-IRVNSVSPGYIRTELV------EPLHEYHRQ-WQPKIPLGRMGR
MAB_4490c|M.abscessus_ATCC_199 WGRYG-ITVNGLAPTVFRSPLTSWMFTDEPAAQATRENFLSRIPLGRLGE
TH_2623|M.thermoresistible__bu WTPRKGIRVNAIAPGFFKSEMTD----QYKPGYLDSQMPR--VLMGRTGD
Mvan_0894|M.vanbaalenii_PYR-1 WA-RYNVRVNALAPGFFPSELTT----ELLDDDAGGAYIRRNTPMARAGR
Mflv_1825|M.gilvum_PYR-GCK LAPR--IRVNAIAPGSILTSALE----IVASNDDLRDPMEKATPMKRLGD
MSMEG_3604|M.smegmatis_MC2_155 WAPLG-IRVNALAPGYVKTDMAP----VDRP--EFKRYWIDDTPQLRYAV
MLBr_01807|M.leprae_Br4923 LGSRS-ITANVVAPGFIDTEMTR------AMDSKYQEAALQAIPLGRIGA
MUL_3898|M.ulcerans_Agy99 LAHVG-VRVNAIAPGLIRSAMTE------AMPQRIWDQKLAEVPMGRAGE
: .* ::* . : * .
Mb1963c|M.bovis_AF2122/97 PEELAGLYLYLASEASSYMTGSDIVIDGGYTCP---------
Rv1928c|M.tuberculosis_H37Rv PEELAGLYLYLASEASSYMTGSDIVIDGGYTCP---------
MMAR_2849|M.marinum_M PEELTGLYLYLASAASSYMTGSDIVIDGGYTCP---------
MAV_2775|M.avium_104 PDELAGIYLYLASAASSYMTGSDIVIDGGYSCP---------
MAB_4490c|M.abscessus_ATCC_199 PEDLAGPILFLSAPASDFLTGHVVYPDGGYTAG---------
TH_2623|M.thermoresistible__bu PEELAATLVWLVSDAGGYVTGQTIVVDGGITIT---------
Mvan_0894|M.vanbaalenii_PYR-1 AGELSGALLLLASGAGSFITGQVIAVDGGWTAR---------
Mflv_1825|M.gilvum_PYR-GCK PLDIAAAAVYLASPAGSYLTGKTLEVDGGITFPNLELPIPDL
MSMEG_3604|M.smegmatis_MC2_155 PEEIAPSVVFLASDAASFITGSVLVADGGYTAW---------
MLBr_01807|M.leprae_Br4923 VEEIAGAVSFLASEDAGYISGAVIPVDGGLGMGH--------
MUL_3898|M.ulcerans_Agy99 PSEVASVALFLACDLSSYMTGTVLDVTGGRFI----------
::: * . ..:::* : **