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TVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALALRSAGAEVVVAARRADRLAELCEAHEGL SAVSCDVADPASIESAYQCVEERVGAVDILVNNAGTSIPARAEDESLTDFQYVLDVNLVGAFRLTQLVGR KMIERGEGSIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQWARYNVRVNALAPGFFPSELTTE LLDDDAGGAYIRRNTPMARAGRAGELSGALLLLASGAGSFITGQVIAVDGGWTAR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_0894 | - | - | 100% (266) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_0441 | - | 2e-36 | 37.60% (258) | short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_2752 | - | 7e-35 | 37.82% (238) | 3-oxoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 1e-40 | 37.70% (252) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2424 | - | 5e-35 | 38.78% (245) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1928c | - | 1e-40 | 37.70% (252) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-32 | 36.13% (238) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4490c | - | 5e-36 | 34.88% (258) | oxidoreductase |
| M. marinum M | MMAR_2849 | - | 6e-43 | 37.45% (251) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2775 | - | 1e-40 | 36.86% (255) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3420 | - | 9e-47 | 39.92% (253) | gluconate 5-dehydrogenase |
| M. thermoresistible (build 8) | TH_3791 | - | 4e-62 | 50.81% (248) | PUTATIVE putative short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_1491 | fabG1 | 7e-35 | 35.52% (259) | 3-oxoacyl- |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1963c|M.bovis_AF2122/97 -------------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQ
Rv1928c|M.tuberculosis_H37Rv -------------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQ
MMAR_2849|M.marinum_M -------------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQ
MAV_2775|M.avium_104 ---------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGAR
Mvan_0894|M.vanbaalenii_PYR-1 MTVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALALRSAGAE
TH_3791|M.thermoresistible__bu MTANTG------ASVLD-MFRLTGRSAIVTGASSGLGRGFAQTLAAAGAT
MLBr_01807|M.leprae_Br4923 -MTDAAAKVS--AAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR
MUL_1491|M.ulcerans_Agy99 -MTDTATEQNTESAADGGKPAFVSRSVLVTGGNRGIGLAIAQRLATDGHR
Mflv_2424|M.gilvum_PYR-GCK ------------MAITASDILLTGRVAVVTGGGAGIGRGIAQGLAAFGAS
MSMEG_3420|M.smegmatis_MC2_155 ---------------MTGLFDLTGRLAVVTGSSRGIGLAIAAGLAEAGAR
MAB_4490c|M.abscessus_ATCC_199 -----------MFDDPRALFDIAGKSAIVIGATGSLGQIASRALAGAGAN
: .: :: *. .:* : *
Mb1963c|M.bovis_AF2122/97 VAIAARHLDALEK-LADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAE
Rv1928c|M.tuberculosis_H37Rv VAIAARHLDALEK-LADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAE
MMAR_2849|M.marinum_M VAVAARHSDALQV-VADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGE
MAV_2775|M.avium_104 VAIAARDFEALQR-TADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAE
Mvan_0894|M.vanbaalenii_PYR-1 VVVAARRADR------LAELCEAHEGLSAVSCDVADPASIESAYQCVEER
TH_3791|M.thermoresistible__bu VYAAARRTDR------LETLAAENPAIRAVTCDVTDEQDRRALVERVVAE
MLBr_01807|M.leprae_Br4923 VAVTHR-------------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEH
MUL_1491|M.ulcerans_Agy99 VAVTHR-------------GSGAPEGLFGVECDVTDNDAVDRAFKEVEEH
Mflv_2424|M.gilvum_PYR-GCK VAIWERDP-------DTCAAAAAAIGGLGLEVDVRDAAAVDTALDRTERE
MSMEG_3420|M.smegmatis_MC2_155 VVLNGVDGPRLEHTCDGLREKFGTDAVYAARFDVTDPDEVSSAIDDIEQR
MAB_4490c|M.abscessus_ATCC_199 VAICGSREDALSD--LRDELAAAPGCIVPIARRPDSESASDAIVKETIEA
* . .
Mb1963c|M.bovis_AF2122/97 LGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMV
Rv1928c|M.tuberculosis_H37Rv LGGIDIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMV
MMAR_2849|M.marinum_M LGGIDIAVCNAGIVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMV
MAV_2775|M.avium_104 LGGIDIAVCNAGIISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMV
Mvan_0894|M.vanbaalenii_PYR-1 VGAVDILVNNAGTSIPARAEDESLTDFQYVLDVNLVGAFRLTQLVGRKMI
TH_3791|M.thermoresistible__bu TGGVDVLVNNAGKPGGPDAVKESADEFASILDLNLAAGFHLSCDVVRANP
MLBr_01807|M.leprae_Br4923 QGPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMI
MUL_1491|M.ulcerans_Agy99 QGPVEVLVSNAGLSADAFLIRMTEERFEKVIDANLTGAFRVAQRASRSMQ
Mflv_2424|M.gilvum_PYR-GCK LGTVSILVNNAGGTFNSPLLDTSENGWDALYRSNLRHVLLCTQRVARRLV
MSMEG_3420|M.smegmatis_MC2_155 IGPIEVLVNNAGLQHREPLLEVSLANWQRVIDVDLTSAFLVGREVARHQL
MAB_4490c|M.abscessus_ATCC_199 FGGVDILVVASGVNEVAPAVDMQPARFEAVLDANVTSTWLAVRSAGRAMI
* :.: * :* : : :: . :
Mb1963c|M.bovis_AF2122/97 KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK
Rv1928c|M.tuberculosis_H37Rv KQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHK
MMAR_2849|M.marinum_M DQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQ
MAV_2775|M.avium_104 RQGRGGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHD
Mvan_0894|M.vanbaalenii_PYR-1 E-RGEGSIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQWARYN
TH_3791|M.thermoresistible__bu E-NHRLSIVNVSSVIGLVSTAPIGGAGYAASKAGVLGLTRELAGQWGRQG
MLBr_01807|M.leprae_Br4923 K-QRFGRYIFMGSVVGLSGVP--GQANYAASKSGLIGMARSLARELGSRS
MUL_1491|M.ulcerans_Agy99 R-KKFGRLIFIGSVSGSWGIG--NQANYAASKAGVIGMARSIARELSKVN
Mflv_2424|M.gilvum_PYR-GCK AAEQTGSVINVTSIEGSRAAP--GYAAYAAAKAGVVNYTKTASFELAPYG
MSMEG_3420|M.smegmatis_MC2_155 A-RGSGKIINICSVQTDLARP--SIAAYTAAKGGLRNLTRAMTAEWAGGG
MAB_4490c|M.abscessus_ATCC_199 ERGRGGKIILTSSARGKLGHP-AGYTAYCASKAAVDGLVRSFGCEWGRYG
: * * ::*..: .: : .
Mb1963c|M.bovis_AF2122/97 IRVNSVSPGYILTELVEPYTEYQ---PLWEP----KIPLGRLGRPEELAG
Rv1928c|M.tuberculosis_H37Rv IRVNSVSPGYILTELVEPYTEYQ---PLWEP----KIPLGRLGRPEELAG
MMAR_2849|M.marinum_M IRVNSVSPGYIRTELVEPLADYH---ALWEP----KIPLGRMGRPEELTG
MAV_2775|M.avium_104 IRVNSVSPGYIRTELVEPLHEYH---RQWQP----KIPLGRMGRPDELAG
Mvan_0894|M.vanbaalenii_PYR-1 VRVNALAPGFFPSELTTELLDDDAGGAYIRR----NTPMARAGRAGELSG
TH_3791|M.thermoresistible__bu IRVNALVPGWFDTEMTDGLFTNERSATWVRR----NTMLNRGGREGEVDG
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTE-MTRAMDSK-YQEAALQ----AIPLGRIGAVEEIAG
MUL_1491|M.ulcerans_Agy99 VTANVVAPGYIDTD-MTRALDER-IQEGALQ----FIPAKRVGTAAEVAG
Mflv_2424|M.gilvum_PYR-GCK IRVNGLAPDLTMTEGLQKLAFGE-LSGTVAR----MVPMRRAGHVDEMAS
MSMEG_3420|M.smegmatis_MC2_155 LQINGLAPGYIHTEMTQALVDDTSFNNWILG----RTPAGRWGTVDDLVG
MAB_4490c|M.abscessus_ATCC_199 ITVNGLAPTVFRSPLTSWMFTDEPAAQATRENFLSRIPLGRLGEPEDLAG
: * : * : * * :: .
Mb1963c|M.bovis_AF2122/97 LYLYLASEASSYMTGSDIVIDGGYTCP-----------------
Rv1928c|M.tuberculosis_H37Rv LYLYLASEASSYMTGSDIVIDGGYTCP-----------------
MMAR_2849|M.marinum_M LYLYLASAASSYMTGSDIVIDGGYTCP-----------------
MAV_2775|M.avium_104 IYLYLASAASSYMTGSDIVIDGGYSCP-----------------
Mvan_0894|M.vanbaalenii_PYR-1 ALLLLASGAGSFITGQVIAVDGGWTAR-----------------
TH_3791|M.thermoresistible__bu ALLFLASDASSYVTGQAIVVDGGWTAR-----------------
MLBr_01807|M.leprae_Br4923 AVSFLASEDAGYISGAVIPVDGGLGMGH----------------
MUL_1491|M.ulcerans_Agy99 VVSFLASEDASYISGAVIPVDGGMGMGH----------------
Mflv_2424|M.gilvum_PYR-GCK AAVFLASDMASYITGQTIHVDGGTEAAGGWYFHPDNGAPTLGPA
MSMEG_3420|M.smegmatis_MC2_155 PAIFLASPASAYVNGQVLFVDGGMTAVV----------------
MAB_4490c|M.abscessus_ATCC_199 PILFLSAPASDFLTGHVVYPDGGYTAG-----------------
*:: . ::.* : ***