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RYPDLAGKATIVTGAGAGIGLAIAERLAAEGAAVLCADIDGASAEQAAAKIGSGAVGYQVDVSAEEQVAG MVEACVTSFGGLDKLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGGAIVNMSS LAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLPAFVDTPMQQSAMAMFDEVLGTGGANTM IARLQGRMARPEEMARIVAFLLPDDSSMITGTTQIADGGTIAALW*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_2885 | - | - | 100% (256) | short-chain type dehydrogenase/reductase |
| M. ulcerans Agy99 | MUL_0336 | - | 3e-38 | 38.52% (257) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_3898 | fabG | 6e-38 | 37.60% (242) | 3-ketoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1976 | - | 1e-111 | 76.95% (256) | short-chain type dehydrogenase/reductase |
| M. gilvum PYR-GCK | Mflv_4505 | - | 4e-38 | 34.66% (251) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1941 | - | 1e-111 | 76.95% (256) | short-chain type dehydrogenase/reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 5e-29 | 31.17% (247) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_4680c | - | 4e-37 | 37.50% (248) | putative short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_2869 | - | 1e-139 | 98.83% (256) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_5088 | fabG | 1e-44 | 44.76% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. smegmatis MC2 155 | MSMEG_2206 | fabG | 6e-40 | 38.31% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. thermoresistible (build 8) | TH_3693 | - | 2e-40 | 38.71% (248) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_3999 | - | 1e-111 | 77.95% (254) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4505|M.gilvum_PYR-GCK -----------MTGR---LAGKVALISGAARGMGASHARVMAGHGAKVVC
MAB_4680c|M.abscessus_ATCC_199 -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MUL_2885|M.ulcerans_Agy99 -----------MRYP--DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC
MMAR_2869|M.marinum_M -----------MRYP--DLAGKATIVTGAGAGIGLAIAERLAAEGAAVLC
Mvan_3999|M.vanbaalenii_PYR-1 -----------MTYP--DLADKAVIVTGAAAGIGLAIAERLAAERCRVVC
Mb1976|M.bovis_AF2122/97 -----------MNHP--DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
Rv1941|M.tuberculosis_H37Rv -----------MNHP--DLAGKVAIVTGAGAGIGLAVARRLADEGCHVLC
MSMEG_2206|M.smegmatis_MC2_155 -----------------MLTGQTAVVTGGAQGLGLAIAKRFISEGARVVL
TH_3693|M.thermoresistible__bu -------------VS--LLAGQTAVVTGGARGLGYAIAERFIAEGARVVI
MAV_5088|M.avium_104 -----------MAES--LLLGKVAVVTGAGQGIGREIARALHRHGARVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
: .: :::*. *:* :. : . *
Mflv_4505|M.gilvum_PYR-GCK GDILDSDGEAVAAELGDA---ARYVHLDVTSPDDWDRAVAAAVADFGGLD
MAB_4680c|M.abscessus_ATCC_199 ADVLDGDGRQLAAELGDA---ARFTHLDVTDAEQWRELIDTTLAGFGTIT
MUL_2885|M.ulcerans_Agy99 ADIDGASAEQAAAKIGSG---AVGYQVDVSAEEQVAGMVEACVTSFGGLD
MMAR_2869|M.marinum_M ADIDGASAEQAAAKIGSG---AVGYQVDVSAEEQVAGMVEACVTSFGGLD
Mvan_3999|M.vanbaalenii_PYR-1 ADIDGAAADAAAAAIGNG---AVGYAVDVSDEPQVVGMVEACVAAFGGVD
Mb1976|M.bovis_AF2122/97 ADIDGDAADAAATKIGCG---AAACRVDVSDEQQIIAMVDACVAAFGGVD
Rv1941|M.tuberculosis_H37Rv ADIDGDAADAAATKIGCG---AAACRVDVSDEQQIIAMVDACVAAFGGVD
MSMEG_2206|M.smegmatis_MC2_155 GDLNSEATEAAVEELGGS-EVAAAVRCDVTSSADVDALVQAAVERFGGLD
TH_3693|M.thermoresistible__bu GDIDESATRAAADSLGGA-DVAVGMRCDVTRSDEVEALVGAAVKRFGSLD
MAV_5088|M.avium_104 ADLDGSAARSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGGLD
MLBr_01807|M.leprae_Br4923 THRASVVPDWFFG-----------VECDVTDNDAIGAAFKAVEEHQGPVE
. **: . * :
Mflv_4505|M.gilvum_PYR-GCK VLVNNAGILNIGTVEDYELSEWHRILDVNLTGVFLGIRAATPTMKAAGRG
MAB_4680c|M.abscessus_ATCC_199 GLVNNAGISSAAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHGCG
MUL_2885|M.ulcerans_Agy99 KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG
MMAR_2869|M.marinum_M KLVANAGVVHLAPILDTAVEDFDRVIGINLRGAWLCTKHAAPKMVERGGG
Mvan_3999|M.vanbaalenii_PYR-1 KLVANAGVVHFAPLTETTVDDFDRIIGINLRGAWLCTKHAAPRMAERGGG
Mb1976|M.bovis_AF2122/97 KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
Rv1941|M.tuberculosis_H37Rv KLVANAGVVHLASLIDTTVEDFDRVIAINLRGAWLCTKHAAPRMIERGGG
MSMEG_2206|M.smegmatis_MC2_155 IMVNNAGITRDATLRKMTEEQFDQVIAVHLKGTWNGTKAAAAIMRENKRG
TH_3693|M.thermoresistible__bu VMVNNAGITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMREQKRG
MAV_5088|M.avium_104 VFVNNAGITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRERKTG
MLBr_01807|M.leprae_Br4923 VLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRFG
:* ***: : .: :: ::* *.: : . * *
Mflv_4505|M.gilvum_PYR-GCK SIINIASIEGMAGTVGCHGYTATKFAVRGLTKSTALELGPFGIRVNSVHP
MAB_4680c|M.abscessus_ATCC_199 SIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSVHP
MUL_2885|M.ulcerans_Agy99 AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP
MMAR_2869|M.marinum_M AIVNMSSLAGHIGVGGTAAYGMSKAGISHLSRVTAAELRSANVRSNALLP
Mvan_3999|M.vanbaalenii_PYR-1 AIVNMSSLGGLVAAAGTAAYGMSKAGIIHLSRITAAEMRSANIRSNALLP
Mb1976|M.bovis_AF2122/97 AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
Rv1941|M.tuberculosis_H37Rv AIVNLSSLAGQVAVGGTGAYGMSKAGIIQLSRITAAELRSSGIRSNTLLP
MSMEG_2206|M.smegmatis_MC2_155 AIVNMSSISGKVGLIGQTNYSAAKAGIVGMTKAAAKELAYLGVRVNAIQP
TH_3693|M.thermoresistible__bu AIVNMSSISGKVGMVGQTNYSAAKAGIVGMTKAASKELAYLGVRVNAIQP
MAV_5088|M.avium_104 SIVNMSSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQP
MLBr_01807|M.leprae_Br4923 RYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVVAP
: :.* * . * :* .: ::: : *: : * : *
Mflv_4505|M.gilvum_PYR-GCK GLVKTPMADWV--------PEDIFQSALG----RIAQPHEVSNLVVYLAS
MAB_4680c|M.abscessus_ATCC_199 GVIYTPMTAKEGFREG---EGNMPIAAMG----RVGNADEVAGAVAYLLS
MUL_2885|M.ulcerans_Agy99 AFVDTPMQQSAMAMFDEVLGTGGANTMIARLQGRMARPEEMARIVAFLLP
MMAR_2869|M.marinum_M AFVDTPMQQSAMAMFDEALGTGGANTMIARLQGRMARPEEMASIVAFLLS
Mvan_3999|M.vanbaalenii_PYR-1 AFVDTPMQQTAMTMFDEALGDGGAATMIGRLQGRMAGPAEMAGVVAFLLS
Mb1976|M.bovis_AF2122/97 AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS
Rv1941|M.tuberculosis_H37Rv AFVDTPMQQTAMAMFDGALGAGGARSMIARLQGRMAAPEEMAGIVVFLLS
MSMEG_2206|M.smegmatis_MC2_155 GLIRSAMTE---AMPQRIWDEKLAEIPMG----RAGEPDEVAKVALFLAS
TH_3693|M.thermoresistible__bu GLIRSAMTE---AMPQRIWDEKLAEIPMG----RAGEPEEVAKVALFLAS
MAV_5088|M.avium_104 GLIRTPMTA---AMPPDVFAEREAAVPMK----RAGEPEEVAGAVVFLAS
MLBr_01807|M.leprae_Br4923 GFIDTEMTR---AMDSKYQEAALQAIPLG----RIGAVEEIAGAVSFLAS
..: : * : * . *:: . :* .
Mflv_4505|M.gilvum_PYR-GCK DESSYSTGAEFVVDGGTLAGLAHKDFSAVDVDQQPEWIT
MAB_4680c|M.abscessus_ATCC_199 DAASYVTGAELAVDGGWTAGPTLTTITGQ----------
MUL_2885|M.ulcerans_Agy99 DDSSMITGTTQIADGGTIAALW-----------------
MMAR_2869|M.marinum_M DDSSMITGTTQIADGGTIAALW-----------------
Mvan_3999|M.vanbaalenii_PYR-1 DAASMVNGTAQLADGGTLAALW-----------------
Mb1976|M.bovis_AF2122/97 DDASMITGTTQIADGGTIAALW-----------------
Rv1941|M.tuberculosis_H37Rv DDASMITGTTQIADGGTIAALW-----------------
MSMEG_2206|M.smegmatis_MC2_155 DLSSYMTGTVLEVTGGRHV--------------------
TH_3693|M.thermoresistible__bu DLSSYMTGTVLEVTGGRHL--------------------
MAV_5088|M.avium_104 ELSSYITGTVLGVGGGRYM--------------------
MLBr_01807|M.leprae_Br4923 EDAGYISGAVIPVDGGLGMGH------------------
: :. .*: . **