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SAELEIDVKTRILDAAADAFMVHGFANTTIDDIAEQVGATKGLIYYHFRSKFDIFLAVYEDGMRRVRERV EPHAGGAGTGRERLVAMSVAHLENLMTELGYHHVVHQGVRYQASTALKIRQRDALAALNELRRDYELMFR RVVAEGIADGSLRVVDEALATRTLLSNLNAVDMWYRRIEGQTLDEINELATNVVDLLITGMANPQGRPR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_5346 | - | - | 100% (210) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 2e-09 | 42.86% (77) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6009 | - | 2e-08 | 25.37% (201) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 5e-07 | 37.35% (83) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 5e-10 | 27.37% (179) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 6e-07 | 37.35% (83) | transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-09 | 26.79% (168) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4912c | - | 1e-11 | 27.36% (201) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4335 | - | 8e-10 | 32.50% (120) | TetR family transcriptional regulator |
| M. avium 104 | MAV_1611 | - | 1e-09 | 50.00% (54) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3462 | - | 3e-25 | 30.05% (193) | PUTATIVE putative transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0145 | - | 5e-10 | 32.50% (120) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 3e-09 | 51.85% (54) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4335|M.marinum_M -------MSTDSHGRRWAKTDA-----------------TQR----RILD
MUL_0145|M.ulcerans_Agy99 -------MSTDSHGRRWAKTDA-----------------TQR----RILD
Mflv_2460|M.gilvum_PYR-GCK ---------MVERWTRERRLEH-----------------TRS----VLLD
Mvan_4194|M.vanbaalenii_PYR-1 ---------MAERWTRERRLEH-----------------TRS----VLLD
Mb1561|M.bovis_AF2122/97 -------MSRASARRRRAVSDE-----------------DKSQRRDEILA
Rv1534|M.tuberculosis_H37Rv -------MSRASARRRRAVSDE-----------------DKSQRRDEILA
MLBr_00815|M.leprae_Br4923 ----MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLI
MAV_1611|M.avium_104 -------MLLGMSPVKPLRSRP-----------------TRGEVRDRILD
MSMEG_5346|M.smegmatis_MC2_155 ---------MSAELEIDVKT--------------------------RILD
TH_3462|M.thermoresistible__bu LTGESDADTVADSARRRRLTAR------------------QSAGRNEVLR
MAB_4912c|M.abscessus_ATCC_199 ------MTEAGAKPRRGRPPASDG---------------DAAATRQRIME
::
MMAR_4335|M.marinum_M AATEVFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQMAS
MUL_0145|M.ulcerans_Agy99 AATEVFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQMAS
Mflv_2460|M.gilvum_PYR-GCK AAEEVFAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWR
Mvan_4194|M.vanbaalenii_PYR-1 AAEEVFAEKGFTPATLDDIARTAGYTKGAIYKHFATKEDLFLAVSDRYWR
Mb1561|M.bovis_AF2122/97 AAKIVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEE
Rv1534|M.tuberculosis_H37Rv AAKIVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEE
MLBr_00815|M.leprae_Br4923 VASDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMN
MAV_1611|M.avium_104 AAAKVFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFE
MSMEG_5346|M.smegmatis_MC2_155 AAADAFMVHGFANTTIDDIAEQVGATKGLIYYHFRSKFDIFLAVYEDGMR
TH_3462|M.thermoresistible__bu AAAEAFTTRGYAATSIDDIADRLHATKGRVYHYFRTKGDIFIGIHKRALE
MAB_4912c|M.abscessus_ATCC_199 VATDLFAEKGFHATGVAEIGAAAGVRGGALYYHIGSKEELLWEILRSYID
.* * .*: : : : :* : * :: :
MMAR_4335|M.marinum_M AVEGKIEEALQQAG---------------------DETDRRRIFELGVRA
MUL_0145|M.ulcerans_Agy99 AVEGKIEEALQQAG---------------------DETDRRRIFELGVRA
Mflv_2460|M.gilvum_PYR-GCK RYFDNFAEVMSSASRVGADEL-----------DEIAERWRQLSIDRGAEH
Mvan_4194|M.vanbaalenii_PYR-1 RYFDNFAEVMASASRVGAHEL-----------DEIAERWRQLSIDRGADH
Mb1561|M.bovis_AF2122/97 ALRAHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDA
Rv1534|M.tuberculosis_H37Rv ALRAHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDA
MLBr_00815|M.leprae_Br4923 NLVSSVQQALRTTTNNRQRLH-----AAVQAFFDFIEHDGQGYRLIFEND
MAV_1611|M.avium_104 LRGQQIAIALDRSAGDTTAAAR--------------EVSRSVLDSVRDHS
MSMEG_5346|M.smegmatis_MC2_155 RVRERVEPHAGGAGTGRERLVAMS-----VAHLENLMTELGYHHVVHQGV
TH_3462|M.thermoresistible__bu ISFDSIRDASDSDAPASEKLHRMAR------AHALMMLNEPTFLRLAGQH
MAB_4912c|M.abscessus_ATCC_199 EMLTEAVHIANMNTEPARRLRTLIG----SYVILIVKYRKQVAIQVRDGS
MMAR_4335|M.marinum_M YLDG--LWEHR-----RVARLLASGDRPTDFGITRRDRMTSAFRSWMAVL
MUL_0145|M.ulcerans_Agy99 YLDG--LWEHR-----RVARLLASGDRPTDFGITRRDRMTSAFRSWMAVL
Mflv_2460|M.gilvum_PYR-GCK AALG--LEFTL-----YLLRNPEARERVEAKRAEVVDQLAEFIVEGMSQL
Mvan_4194|M.vanbaalenii_PYR-1 AALG--LEFTL-----YLLRNPDARERVAAKRAEVVDQLAKFINEGMTRL
Mb1561|M.bovis_AF2122/97 YALGGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAAL
Rv1534|M.tuberculosis_H37Rv YALGGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAAL
MLBr_00815|M.leprae_Br4923 NITEPRVAAQVR---VATESCIDAVFALISADSRLDPHRARMVAVGLVGI
MAV_1611|M.avium_104 DYYVLLVEYWLR-----AQRDPQLRERLIERRRAAADQALHIVESTDTVP
MSMEG_5346|M.smegmatis_MC2_155 RYQASTALKIRQRDALAALNELRRDYELMFRRVVAEGIADGSLRVVDEAL
TH_3462|M.thermoresistible__bu AEMNLASEGRTPREDVDEIRTLRREYEARFERVIARGIESGEFKATDSYL
MAB_4912c|M.abscessus_ATCC_199 ALTGERAAQLQG----LRDELQRCWQRVFDEGHEVGTFHTADHVLTNAIL
MMAR_4335|M.marinum_M ELDSSLHGQFLSRALLAIMEESSLMVAACEEPEQVKPVIDATIEWIGRLT
MUL_0145|M.ulcerans_Agy99 ELDSSLHGQFLSRALLR--------------------------SWRSRH-
Mflv_2460|M.gilvum_PYR-GCK GATLLIEPSTFARALVATS-DSVVLGSQLDAVDLYRPMVEMYVSVIKLPD
Mvan_4194|M.vanbaalenii_PYR-1 GASLLISPLTFAQALVATS-DSVVLASQLDDIDLYRPVVEMYTSVIKLPD
Mb1561|M.bovis_AF2122/97 VGQLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART-
Rv1534|M.tuberculosis_H37Rv VGQLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART-
MLBr_00815|M.leprae_Br4923 SVDCARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----------
MAV_1611|M.avium_104 GDRRLTDIAQLVVTLNLGVAMEEVLRPGTINPDLLAQLITALLESIPV--
MSMEG_5346|M.smegmatis_MC2_155 ATRTLLSNLNAVDMWYRRIEGQTLDEINELATNVVDLLITGMANPQGRPR
TH_3462|M.thermoresistible__bu MAKAVLGTLNWMSRWYHPG-GDTDEDRFRIATSIADFVVSGLRPTEADG-
MAB_4912c|M.abscessus_ATCC_199 GMLNMVAVWYRTDGKSPAQIAKRIADMVLDGIHVDRPEEHAEQAPTDRK-
MMAR_4335|M.marinum_M E
MUL_0145|M.ulcerans_Agy99 -
Mflv_2460|M.gilvum_PYR-GCK -
Mvan_4194|M.vanbaalenii_PYR-1 -
Mb1561|M.bovis_AF2122/97 -
Rv1534|M.tuberculosis_H37Rv -
MLBr_00815|M.leprae_Br4923 -
MAV_1611|M.avium_104 -
MSMEG_5346|M.smegmatis_MC2_155 -
TH_3462|M.thermoresistible__bu -
MAB_4912c|M.abscessus_ATCC_199 -