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M. thermoresistible (build 8) TH_3462 (-)

annotation: putative transcriptional regulator, TetR family
coordinates: 257797 - 258471
length: 225

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_3462--100% (225)putative transcriptional regulator, TetR family
M. thermoresistible (build 8)TH_4438-2e-3958.91% (129) PUTATIVE -
M. thermoresistible (build 8)TH_0160-1e-1632.94% (170) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0163-2e-1631.76% (170) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_0719-3e-1834.71% (170) TetR family transcriptional regulator
M. tuberculosis H37RvRv0158-2e-1631.76% (170) TetR family transcriptional regulator
M. leprae Br4923MLBr_00815-1e-0725.47% (106) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4574c-9e-2032.71% (214) TetR family transcriptional regulator
M. marinum MMMAR_0381-1e-1531.18% (170) TetR family transcriptional regulator
M. avium 104MAV_5138-9e-1530.59% (170) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_5346-6e-2530.05% (193) TetR-family protein transcriptional regulator
M. ulcerans Agy99MUL_4731-7e-1631.18% (170) TetR family transcriptional regulator
M. vanbaalenii PYR-1Mvan_0126-6e-1831.41% (191) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb0163|M.bovis_AF2122/97            ---------------------------MPSDTS-PNGLSRREELLAVATK
Rv0158|M.tuberculosis_H37Rv         ---------------------------MPSDTS-PNGLSRREELLAVATK
MMAR_0381|M.marinum_M               ---------------------------MPSET----GLSRREELLAVATK
MUL_4731|M.ulcerans_Agy99           ---------------------------MPSET----GLSRREELLAVATK
MAV_5138|M.avium_104                ---------------------------MPADSSTPNGQTRREELLAVATK
Mflv_0719|M.gilvum_PYR-GCK          -------------------------------------MSRREELLAVATK
Mvan_0126|M.vanbaalenii_PYR-1       ---------------------------MSESTT--NGMSRREELLAVATK
MAB_4574c|M.abscessus_ATCC_199      --------------------MQPVPEASKAGSSSQRRAGRREELVAVASK
TH_3462|M.thermoresistible__bu      --------------LTGESDADTVADSARRRRLTARQSAGRNEVLRAAAE
MSMEG_5346|M.smegmatis_MC2_155      -------------------------------MSAELEIDVKTRILDAAAD
MLBr_00815|M.leprae_Br4923          MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
                                                                            : .:: .*:.

Mb0163|M.bovis_AF2122/97            LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA
Rv0158|M.tuberculosis_H37Rv         LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLA
MMAR_0381|M.marinum_M               LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLG
MUL_4731|M.ulcerans_Agy99           LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILFDIYRQAAEGTLG
MAV_5138|M.avium_104                LFAARGYHGTRMDDVADVIGLNKATVYHYYASKSLILYDIYQQAAERTLA
Mflv_0719|M.gilvum_PYR-GCK          LFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVD
Mvan_0126|M.vanbaalenii_PYR-1       LFAARGYHGTRMDDVADAVGLNKATVYHYYASKSLILYDIYKGAADFTVD
MAB_4574c|M.abscessus_ATCC_199      LFAARGYHGTRMDDIADVAGLNKATVYHYFASKALILYEIYFKAAEETLA
TH_3462|M.thermoresistible__bu      AFTTRGYAATSIDDIADRLHATKGRVYHYFRTKGDIFIGIHKRALEISFD
MSMEG_5346|M.smegmatis_MC2_155      AFMVHGFANTTIDDIAEQVGATKGLIYYHFRSKFDIFLAVYEDGMRRVRE
MLBr_00815|M.leprae_Br4923          VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
                                     *  :*:  : :*::*:    .*  :* :: :*  :   :          

Mb0163|M.bovis_AF2122/97            AVHD--DPSWTAREALYQYTVRLLTAIASNP--ERAAVYFQEQPYITEWF
Rv0158|M.tuberculosis_H37Rv         AVHD--DPSWTAREALYQYTVRLLTAIASNP--ERAAVYFQEQPYITEWF
MMAR_0381|M.marinum_M               ALHA--EPSWTAREALYQYTVRLLTGIADNP--ERAAVYFQEQPYIAEWF
MUL_4731|M.ulcerans_Agy99           ALHA--EPSWTAREALYQYTVRLLTGIADNP--ERAAVYFQEQPYIAEWF
MAV_5138|M.avium_104                AVHD--DPSMTAREALYQYTVRLLDQIAANP--EGAAVYFQEQPYITEWF
Mflv_0719|M.gilvum_PYR-GCK          ALHD--DPTASARETIYHFTRRLLVGIASDI--ERAAVYFQEGPYISEWF
Mvan_0126|M.vanbaalenii_PYR-1       ALHD--DPTATARETIYHFTRRLLVGIANDI--ERAAVYFQEGPYITEWF
MAB_4574c|M.abscessus_ATCC_199      CLQD--DPRWSARESLYQCTSRMLALIFSNR--EQGAVYFQENPFLSEWL
TH_3462|M.thermoresistible__bu      SIRDASDSDAPASEKLHRMARAHALMMLNEPTFLRLAGQHAEMNLASEGR
MSMEG_5346|M.smegmatis_MC2_155      RVEPHAGGAGTGRERLVAMSVAHLENLMTELGYHHVVHQGVRYQASTALK
MLBr_00815|M.leprae_Br4923          SVQQALRTTTNNRQRLHAAVQAFFDFIEHDG---QGYRLIFENDNITEPR
                                     :.          : :          :  :           .    :   

Mb0163|M.bovis_AF2122/97            TS--EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMT
Rv0158|M.tuberculosis_H37Rv         TS--EQVAEVREKEQQVYEHVHGLIDRGIASGEFYECDSHVVALGYIGMT
MMAR_0381|M.marinum_M               TP--EQVAEVREKEAQVHEHVHGLIDRGIASGEFYECDSHVVALGYIGMT
MUL_4731|M.ulcerans_Agy99           TP--EQVAEVREKEAQVHEHVHGLIDRGIASGEFYECDSHVVALGYIGMT
MAV_5138|M.avium_104                TK--EQVAAVREKETQVYEHVHGLIDRGIASGEFYECDSHVLALGYIGMT
Mflv_0719|M.gilvum_PYR-GCK          TE--EQVDYIREKEAQVYEHVRDVIDRGIASGEFNDCDSHVLALGYIGMT
Mvan_0126|M.vanbaalenii_PYR-1       TE--EQVEYIREKETQVYEHVRDVIDRGIASGEFYDCDSHVLALGYIGMT
MAB_4574c|M.abscessus_ATCC_199      SP--EQVAEIRTREDMVQERVQNIIERGIASGEFVECDSHVMALGYIGMV
TH_3462|M.thermoresistible__bu      TPR-EDVDEIRTLRREYEARFERVIARGIESGEFKATDSYLMAKAVLGTL
MSMEG_5346|M.smegmatis_MC2_155      IRQRDALAALNELRRDYELMFRRVVAEGIADGSLRVVDEALATRTLLSNL
MLBr_00815|M.leprae_Br4923          VA-----AQVRVATESCIDAVFALIS---ADSRLDPHRARMVAVGLVGIS
                                             :.         .  ::     .. :      : :   :.  

Mb0163|M.bovis_AF2122/97            LGSYRWLR-PSGRRTAK--EIAAEFSTALLRGLIRDESIRNQSPLGTRKE
Rv0158|M.tuberculosis_H37Rv         LGSYRWLR-PSGRRTAK--EIAAEFSTALLRGLIRDESIRNQSPLGTRKE
MMAR_0381|M.marinum_M               LGSYRWLR-PHGRRTAR--EIAAEFSTALLRGLIRDESIRNQSPLGS---
MUL_4731|M.ulcerans_Agy99           LGSYRWLR-PHGRRTAR--EIAAEFSTALLRGLIRDESIRNQSPLGS---
MAV_5138|M.avium_104                LGAYRWLR-PSGRRSAK--EIAAEFSTALLRGLIRDEEIRTTSPLGP---
Mflv_0719|M.gilvum_PYR-GCK          LGSYRWLR-PHGRRTAQ--EIAVEFSSALLRGLIRDETVRATSPLGVGID
Mvan_0126|M.vanbaalenii_PYR-1       LGSYRWLR-PHGRRTAQ--EIAVEFSTALLRGLIRDETVRTLSPLGVGID
MAB_4574c|M.abscessus_ATCC_199      LGSYRWLN-PSGRRSAQ--EIAVEFSTTLLRGLIRDEATRINDPLGVASA
TH_3462|M.thermoresistible__bu      NWMSRWYH-PGGDTDEDRFRIATSIADFVVSGLRPTEADG----------
MSMEG_5346|M.smegmatis_MC2_155      NAVDMWYRRIEGQTLDEINELATNVVDLLITGMANPQGRPR---------
MLBr_00815|M.leprae_Br4923          VDCARYWLDTNRPISKS--DAVEGTVQFAWGGLSHVPLTRL---------
                                         :               .         *:                 

Mb0163|M.bovis_AF2122/97            T-----------
Rv0158|M.tuberculosis_H37Rv         T-----------
MMAR_0381|M.marinum_M               ------------
MUL_4731|M.ulcerans_Agy99           ------------
MAV_5138|M.avium_104                ------------
Mflv_0719|M.gilvum_PYR-GCK          VTAKQ-------
Mvan_0126|M.vanbaalenii_PYR-1       APVKTRILEEPS
MAB_4574c|M.abscessus_ATCC_199      TSLDGAR-----
TH_3462|M.thermoresistible__bu      ------------
MSMEG_5346|M.smegmatis_MC2_155      ------------
MLBr_00815|M.leprae_Br4923          ------------