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MVERWTRERRLEHTRSVLLDAAEEVFAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWR RYFDNFAEVMSSASRVGADELDEIAERWRQLSIDRGAEHAALGLEFTLYLLRNPEARERVEAKRAEVVDQ LAEFIVEGMSQLGATLLIEPSTFARALVATSDSVVLGSQLDAVDLYRPMVEMYVSVIKLPD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2460 | - | - | 100% (201) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 1e-57 | 54.50% (200) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2461 | - | 2e-50 | 48.99% (198) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 4e-08 | 34.25% (73) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 4e-08 | 34.25% (73) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00949 | - | 1e-08 | 39.71% (68) | hypothetical protein MLBr_00949 |
| M. abscessus ATCC 19977 | MAB_2913 | - | 2e-16 | 32.95% (173) | TetR family regulatory protein |
| M. marinum M | MMAR_4631 | - | 4e-16 | 33.52% (179) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 2e-16 | 33.81% (139) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 1e-90 | 83.00% (200) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4015 | - | 2e-10 | 52.83% (53) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0245 | - | 5e-13 | 32.52% (163) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 4e-99 | 89.05% (201) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2460|M.gilvum_PYR-GCK ------------------------MVERWTRERRL--EHTRSVLLDAAEE
Mvan_4194|M.vanbaalenii_PYR-1 ------------------------MAERWTRERRL--EHTRSVLLDAAEE
MSMEG_6807|M.smegmatis_MC2_155 ------------------------MVERWTRERRL--EHTRSLLLDAAEN
MMAR_4631|M.marinum_M ------------------MTPPANTATPARVTKRR--AETRARLVDAAFR
MUL_0245|M.ulcerans_Agy99 --------------------------------------------------
Mb3233|M.bovis_AF2122/97 MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MAB_2913|M.abscessus_ATCC_1997 -----------MYPYRFTVITTGRLLMSTGSTRRR--EHTRARLMQAALD
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
MLBr_00949|M.leprae_Br4923 ------------------------MTTSARTHRWAKTGAIQRRILDAAIE
TH_4015|M.thermoresistible__bu -VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKE
Mflv_2460|M.gilvum_PYR-GCK VFAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYFD
Mvan_4194|M.vanbaalenii_PYR-1 VFAEKGFTPATLDDIARTAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
MSMEG_6807|M.smegmatis_MC2_155 VFSEKGFTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
MMAR_4631|M.marinum_M VFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MUL_0245|M.ulcerans_Agy99 MFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
Mb3233|M.bovis_AF2122/97 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MAB_2913|M.abscessus_ATCC_1997 VFADRGFHGASIENICEKAGFTRGAFYSNFAGKDELFFTLFDASSEQLLT
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
MLBr_00949|M.leprae_Br4923 VFATRSFTTATMTDAMTGSGAIIGSIYHHFGGKRKLFLAIFEQMGRQRRP
TH_4015|M.thermoresistible__bu VFARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQ
:* .: . : :* .* * .::: :
Mflv_2460|M.gilvum_PYR-GCK NFAEVMSSASRVGADELDEIAERWRQLSIDRGAEHAALGLEFTLYLLRNP
Mvan_4194|M.vanbaalenii_PYR-1 NFAEVMASASRVGAHELDEIAERWRQLSIDRGADHAALGLEFTLYLLRNP
MSMEG_6807|M.smegmatis_MC2_155 NFAEVMASAASVGARELDEIAKRWRQLSVDRGAEQAALGLEFTLYLKRNP
MMAR_4631|M.marinum_M QVGTAMASVDDP-TDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARHP
MUL_0245|M.ulcerans_Agy99 QVGTAMASVGDP-TDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARHP
Mb3233|M.bovis_AF2122/97 GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
Rv3208|M.tuberculosis_H37Rv GVHQALSTTTDNRQRLHVAVQAFFDFIEHDSQGYRLIFENDFVTEPEVAA
MAB_2913|M.abscessus_ATCC_1997 QLRAALDECRKSPDPLSTFIRTIDDKGPTQR--RWYLISMEFTLYAIREP
MAV_1611|M.avium_104 QIAIALDRSAGDTTAAAREVSRSVLDSVRDHS-DYYVLLVEYWLRAQRDP
MLBr_00949|M.leprae_Br4923 PHRRGDATSGPIRPSGDRSAAGIRS--------------------PRTGP
TH_4015|M.thermoresistible__bu PVRTDAGTEPKNPYERILRANRTYLEAYRANRAIMIVWEQVASLNEHVEQ
Mflv_2460|M.gilvum_PYR-GCK EARERVEAKRAEVVDQLAEFIVEG-------MSQLGATLLIEPSTFARAL
Mvan_4194|M.vanbaalenii_PYR-1 DARERVAAKRAEVVDQLAKFINEG-------MTRLGASLLISPLTFAQAL
MSMEG_6807|M.smegmatis_MC2_155 EARDRVAAKRSEVVAQLTAFIVAS-------IEKLGATLLISPETFAHAL
MMAR_4631|M.marinum_M DLAQRLAAHRAQLRAAVEDRLAGS-------DVELPAAIG-SVADAARAV
MUL_0245|M.ulcerans_Agy99 DLAQRLAAHRAQLRAAVEDRLAGS-------DVELPAAIG-SVADAARAV
Mb3233|M.bovis_AF2122/97 QVRVATESCIDAVFALISADSGLDPHR----ARMIAVGLVGMSVDCARYW
Rv3208|M.tuberculosis_H37Rv QVRVATESCIDAVFALISADSGLDPHR----ARMIAVGLVGMSVDCARYW
MAB_2913|M.abscessus_ATCC_1997 SAAVVLAEHDARLRREAAGIINEL-------MSIAHRELIIDTELIARLA
MAV_1611|M.avium_104 QLRERLIERRRAAADQALHIVEST--------DTVPGDRR--LTDIAQLV
MLBr_00949|M.leprae_Br4923 TSRRCGKTGTRPGCCRPETHLQAS-----------------------RSP
TH_4015|M.thermoresistible__bu LRREYSDRFAARIERAIIRWQEAGLADPAIDPRYAAAALSGMLSNFAYRW
Mflv_2460|M.gilvum_PYR-GCK VATSDSVVLGSQLD-AVDLYRPMVEMYVSVIKLPD--------
Mvan_4194|M.vanbaalenii_PYR-1 VATSDSVVLASQLD-DIDLYRPVVEMYTSVIKLPD--------
MSMEG_6807|M.smegmatis_MC2_155 VATSDSVVLSSELD-NVDLYRPMVEMYASMIKLPT--------
MMAR_4631|M.marinum_M VAAYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR---------
MUL_0245|M.ulcerans_Agy99 VAAYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR---------
Mb3233|M.bovis_AF2122/97 LDADKPISKSDAVEGTVQFAWGGLSHVPLTRS-----------
Rv3208|M.tuberculosis_H37Rv LDADKPISKSDAVEGTVQFAWGGLSHVPLTRS-----------
MAB_2913|M.abscessus_ATCC_1997 TALREGVAAQFYVEPELAETR-MLERLAFPAMLRAFSQPVGAD
MAV_1611|M.avium_104 VTLNLGVAMEEVLRPGTINPDLLAQLITALLESIPV-------
MLBr_00949|M.leprae_Br4923 VATA---------------------------------------
TH_4015|M.thermoresistible__bu SVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA------