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VERWTRERRLEHTRSLLLDAAENVFSEKGFTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRR YFDNFAEVMASAASVGARELDEIAKRWRQLSVDRGAEQAALGLEFTLYLKRNPEARDRVAAKRSEVVAQL TAFIVASIEKLGATLLISPETFAHALVATSDSVVLSSELDNVDLYRPMVEMYASMIKLPT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6807 | - | - | 100% (201) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0148 | - | 5e-19 | 32.18% (174) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_5346 | - | 2e-09 | 42.86% (77) | TetR-family protein transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 3e-09 | 25.28% (178) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 1e-90 | 83.00% (200) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 1e-09 | 25.84% (178) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-08 | 32.93% (82) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3437c | - | 1e-17 | 30.39% (181) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4631 | - | 5e-14 | 31.43% (175) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 2e-14 | 34.13% (126) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3967 | - | 2e-09 | 37.97% (79) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0245 | - | 5e-11 | 30.19% (159) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 5e-90 | 81.50% (200) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2460|M.gilvum_PYR-GCK --------------------------MVERWTRERRLEHTRSVLLDAAEE
Mvan_4194|M.vanbaalenii_PYR-1 --------------------------MAERWTRERRLEHTRSVLLDAAEE
MSMEG_6807|M.smegmatis_MC2_155 --------------------------MVERWTRERRLEHTRSLLLDAAEN
MMAR_4631|M.marinum_M --------------------MTPPANTATPARVTKRRAETRARLVDAAFR
MUL_0245|M.ulcerans_Agy99 --------------------------------------------------
Mb0310|M.bovis_AF2122/97 -------------------------MGVPAKKKQQQGERSRESILDATER
Rv0302|M.tuberculosis_H37Rv -------------------------MGVPAKKKQQQGERSRESILDATER
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
MAB_3437c|M.abscessus_ATCC_199 --------------------------MSKRLSRTESQELTRAKLIESATR
TH_3967|M.thermoresistible__bu --------------------------MPADNGTARKSDRTRSTILDAARV
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
Mflv_2460|M.gilvum_PYR-GCK VFAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYFD
Mvan_4194|M.vanbaalenii_PYR-1 VFAEKGFTPATLDDIARTAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
MSMEG_6807|M.smegmatis_MC2_155 VFSEKGFTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
MMAR_4631|M.marinum_M VFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MUL_0245|M.ulcerans_Agy99 MFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
Mb0310|M.bovis_AF2122/97 LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Rv0302|M.tuberculosis_H37Rv LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
MAB_3437c|M.abscessus_ATCC_199 LYLENGYVATSTDQVAEAAGFSRGALYSNFRSKEDLALAVLDAHTEEQFQ
TH_3967|M.thermoresistible__bu AFARKGFSGVTIRDITDLAGVTRANFYYYFSDKTELFIELGTDTYREVLA
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
.*: . : .* : .* * : :
Mflv_2460|M.gilvum_PYR-GCK NFAEVMSSASRVGADELDEIAERWRQLSIDRGAEHAALGLEFTLYLLRNP
Mvan_4194|M.vanbaalenii_PYR-1 NFAEVMASASRVGAHELDEIAERWRQLSIDRGADHAALGLEFTLYLLRNP
MSMEG_6807|M.smegmatis_MC2_155 NFAEVMASAASVGARELDEIAKRWRQLSVDRGAEQAALGLEFTLYLKRNP
MMAR_4631|M.marinum_M QVGTAMASVDDP-TDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARHP
MUL_0245|M.ulcerans_Agy99 QVGTAMASVGDP-TDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARHP
Mb0310|M.bovis_AF2122/97 AIPTWDEAHGPVEQRSERQLTELVSLQSQHP--DFLRLFYLLSMERSQDP
Rv0302|M.tuberculosis_H37Rv AIPTWDEAHGPVEQRSERQLTELVSLQSQHP--DFLRLFYLLSMERSQDP
MAV_1611|M.avium_104 QIAIALDRSAGDTTAAAREVSRSVLDSVRDHS-DYYVLLVEYWLRAQRDP
MAB_3437c|M.abscessus_ATCC_199 EIAAVAADLPPE---RFTRFETWLTKSMGDR--RWALFKSEVALSARANP
TH_3967|M.thermoresistible__bu VAESFGEDMSRAG------IDEWVARX---GPVDSADLPAQIASLPAQDA
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITEPRVAA
. : .
Mflv_2460|M.gilvum_PYR-GCK EARERVEAKRAEVVDQL-AEFIVEGMSQ--LGATLLIEPSTFARALVATS
Mvan_4194|M.vanbaalenii_PYR-1 DARERVAAKRAEVVDQL-AKFINEGMTR--LGASLLISPLTFAQALVATS
MSMEG_6807|M.smegmatis_MC2_155 EARDRVAAKRSEVVAQL-TAFIVASIEK--LGATLLISPETFAHALVATS
MMAR_4631|M.marinum_M DLAQRLAAHRAQLRAAV-EDRLAGSDVE--LPAAIG-SVADAARAVVAAY
MUL_0245|M.ulcerans_Agy99 DLAQRLAAHRAQLRAAV-EDRLAGSDVE--LPAAIG-SVADAARAVVAAY
Mb0310|M.bovis_AF2122/97 VVAAVVRRVRNTAIARF-RDSITHLLPSDIPPGKADLVVAELTAFAVALS
Rv0302|M.tuberculosis_H37Rv AVAAVVRRVRNTAIARF-RDSITHLLPSDIPPGKADLVVAELTAFAVALS
MAV_1611|M.avium_104 QLRERLIERRRAAADQA-LHIVESTDTVP-----GDRRLTDIAQLVVTLN
MAB_3437c|M.abscessus_ATCC_199 ELRQQLAARDQLARQAL-SVLLGHVEAE--SGNPLPAAPETLARAILALA
TH_3967|M.thermoresistible__bu AAKLTSAGVRAAVVRSA-TELVGDPHLAARGFFPEIAHPDPQLRTGRLVG
MLBr_00815|M.leprae_Br4923 QVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWLDTN
Mflv_2460|M.gilvum_PYR-GCK DSVVLGSQLD-AVDLYR-------PMVEMYVSVIKLPD--
Mvan_4194|M.vanbaalenii_PYR-1 DSVVLASQLD-DIDLYR-------PVVEMYTSVIKLPD--
MSMEG_6807|M.smegmatis_MC2_155 DSVVLSSELD-NVDLYR-------PMVEMYASMIKLPT--
MMAR_4631|M.marinum_M DGVSIQLLLDGDQDAAR-------AWLSQLLGVVLIR---
MUL_0245|M.ulcerans_Agy99 DGVSIQLLLDGDQDAAR-------AWLSQLLGVVLIR---
Mb0310|M.bovis_AF2122/97 DGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET--
Rv0302|M.tuberculosis_H37Rv DGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET--
MAV_1611|M.avium_104 LGVAMEEVLRPGTINPD--------LLAQLITALLESIPV
MAB_3437c|M.abscessus_ATCC_199 KGIAIEGLVDDEVSPDW--------IIDLVKKGLPQ----
TH_3967|M.thermoresistible__bu LPWRFAGAGPVPLSPPP-------ALGSTPASALYERTPV
MLBr_00815|M.leprae_Br4923 RPISKSDAVEGTVQFAWG------GLSHVPLTRL------
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