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AERWTRERRLEHTRSVLLDAAEEVFAEKGFTPATLDDIARTAGYTKGAIYKHFATKEDLFLAVSDRYWRR YFDNFAEVMASASRVGAHELDEIAERWRQLSIDRGADHAALGLEFTLYLLRNPDARERVAAKRAEVVDQL AKFINEGMTRLGASLLISPLTFAQALVATSDSVVLASQLDDIDLYRPVVEMYTSVIKLPD*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | - | 100% (201) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 1e-56 | 54.50% (200) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4193 | - | 2e-51 | 50.52% (192) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 6e-08 | 26.63% (184) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 3e-99 | 89.05% (201) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 3e-08 | 26.98% (189) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-08 | 31.33% (83) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2913 | - | 2e-16 | 32.37% (173) | TetR family regulatory protein |
| M. marinum M | MMAR_4631 | - | 8e-15 | 32.65% (196) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 9e-16 | 35.07% (134) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 6e-90 | 81.50% (200) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_3967 | - | 1e-09 | 28.78% (139) | PUTATIVE transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_0245 | - | 9e-12 | 31.67% (180) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0310|M.bovis_AF2122/97 -------------------------MGVPAKKKQQQGERSRESILDATER
Rv0302|M.tuberculosis_H37Rv -------------------------MGVPAKKKQQQGERSRESILDATER
Mvan_4194|M.vanbaalenii_PYR-1 --------------------------MAERWTRERRLEHTRSVLLDAAEE
Mflv_2460|M.gilvum_PYR-GCK --------------------------MVERWTRERRLEHTRSVLLDAAEE
MSMEG_6807|M.smegmatis_MC2_155 --------------------------MVERWTRERRLEHTRSLLLDAAEN
MMAR_4631|M.marinum_M --------------------MTPPANTATPARVTKRRAETRARLVDAAFR
MUL_0245|M.ulcerans_Agy99 --------------------------------------------------
MAB_2913|M.abscessus_ATCC_1997 -------------MYPYRFTVITTGRLLMSTGSTRRREHTRARLMQAALD
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
TH_3967|M.thermoresistible__bu --------------------------MPADNGTARKSDRTRSTILDAARV
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
Mb0310|M.bovis_AF2122/97 LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Rv0302|M.tuberculosis_H37Rv LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Mvan_4194|M.vanbaalenii_PYR-1 VFAEKGFTPATLDDIARTAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
Mflv_2460|M.gilvum_PYR-GCK VFAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYFD
MSMEG_6807|M.smegmatis_MC2_155 VFSEKGFTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
MMAR_4631|M.marinum_M VFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MUL_0245|M.ulcerans_Agy99 MFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MAB_2913|M.abscessus_ATCC_1997 VFADRGFHGASIENICEKAGFTRGAFYSNFAGKDELFFTLFDASSEQLLT
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
TH_3967|M.thermoresistible__bu AFARKGFSGVTIRDITDLAGVTRANFYYYFSDKTELFIELGTDTYR---E
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: .*: . : : .* : .* * : :
Mb0310|M.bovis_AF2122/97 AIPTWDEAHGPVEQRSERQLTELVSLQSQHP--DFLRLFYLLSMERSQDP
Rv0302|M.tuberculosis_H37Rv AIPTWDEAHGPVEQRSERQLTELVSLQSQHP--DFLRLFYLLSMERSQDP
Mvan_4194|M.vanbaalenii_PYR-1 NFAEVMASASRVGAHELDEIAERWRQLSIDRGADHAALGLEFTLYLLRNP
Mflv_2460|M.gilvum_PYR-GCK NFAEVMSSASRVGADELDEIAERWRQLSIDRGAEHAALGLEFTLYLLRNP
MSMEG_6807|M.smegmatis_MC2_155 NFAEVMASAASVGARELDEIAKRWRQLSVDRGAEQAALGLEFTLYLKRNP
MMAR_4631|M.marinum_M QVGTAMASVDDP-TDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARHP
MUL_0245|M.ulcerans_Agy99 QVGTAMASVGDP-TDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARHP
MAB_2913|M.abscessus_ATCC_1997 QLRAALDECRKSPDPLSTFIRTIDDKGPTQR--RWYLISMEFTLYAIREP
MAV_1611|M.avium_104 QIAIALDRSAGDTTAAAREVSRSVLDSVRDHS-DYYVLLVEYWLRAQRDP
TH_3967|M.thermoresistible__bu VLAVAESFGEDMSRAGIDEWVARX--GPVDS----ADLPAQIASLPAQDA
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFDFIEHDG----QGYRLIFENDNITEP
. . ..
Mb0310|M.bovis_AF2122/97 VVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSD
Rv0302|M.tuberculosis_H37Rv AVAAVVRRVRNTAIARFRDSITHLLPSDIPPGKADLVVAELTAFAVALSD
Mvan_4194|M.vanbaalenii_PYR-1 DARERVAAKRAEVVDQLAKFINEGMTR--LGASLLISPLTFAQALVATSD
Mflv_2460|M.gilvum_PYR-GCK EARERVEAKRAEVVDQLAEFIVEGMSQ--LGATLLIEPSTFARALVATSD
MSMEG_6807|M.smegmatis_MC2_155 EARDRVAAKRSEVVAQLTAFIVASIEK--LGATLLISPETFAHALVATSD
MMAR_4631|M.marinum_M DLAQRLAAHRAQLRAAVEDRLAGSDVE--LPAAIG-SVADAARAVVAAYD
MUL_0245|M.ulcerans_Agy99 DLAQRLAAHRAQLRAAVEDRLAGSDVE--LPAAIG-SVADAARAVVAAYD
MAB_2913|M.abscessus_ATCC_1997 SAAVVLAEHDARLRREAAGIINELMSI--AHRELIIDTELIARLATALRE
MAV_1611|M.avium_104 QLRERLIERRRAAADQALHIVESTDTVP-----GDRRLTDIAQLVVTLNL
TH_3967|M.thermoresistible__bu AAKLTSAGVRAAVVRSATELVGDPHLA--ARGFFPEIAHPDPQLRTGRLV
MLBr_00815|M.leprae_Br4923 RVAAQVRVATESCIDAVFALISADSRLD-PHRARMVAVGLVGISVDCARY
:
Mb0310|M.bovis_AF2122/97 GVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET--
Rv0302|M.tuberculosis_H37Rv GVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET--
Mvan_4194|M.vanbaalenii_PYR-1 SVVLASQLD-DIDLYR-------PVVEMYTSVIKLPD--
Mflv_2460|M.gilvum_PYR-GCK SVVLGSQLD-AVDLYR-------PMVEMYVSVIKLPD--
MSMEG_6807|M.smegmatis_MC2_155 SVVLSSELD-NVDLYR-------PMVEMYASMIKLPT--
MMAR_4631|M.marinum_M GVSIQLLLDGDQDAAR-------AWLSQLLGVVLIR---
MUL_0245|M.ulcerans_Agy99 GVSIQLLLDGDQDAAR-------AWLSQLLGVVLIR---
MAB_2913|M.abscessus_ATCC_1997 GVAAQFYVEPELAETRMLERLAFPAMLRAFSQPVGAD--
MAV_1611|M.avium_104 GVAMEEVLRPGTINPD--------LLAQLITALLESIPV
TH_3967|M.thermoresistible__bu GLPWRFAGAGPVPLSP-----PPALGSTPASALYERTPV
MLBr_00815|M.leprae_Br4923 WLDTNRPISKSDAVEG----TVQFAWGGLSHVPLTRL--
: