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M. ulcerans Agy99 MUL_0145 (-)

annotation: TetR family transcriptional regulator
coordinates: 151048 - 151551
length: 167

MSTDSHGRRWAKTDATQRRILDAATEVFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQM
ASAVEGKIEEALQQAGDETDRRRIFELGVRAYLDGLWEHRRVARLLASGDRPTDFGITRRDRMTSAFRSW
MAVLELDSSLHGQFLSRALLRSWRSRH
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_0145--100% (167)TetR family transcriptional regulator
M. ulcerans Agy99MUL_2529-8e-1128.06% (139) TetR family transcriptional regulator
M. ulcerans Agy99MUL_0323-5e-0838.37% (86) transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb3233-6e-1128.06% (139) TetR family transcriptional regulator
M. gilvum PYR-GCKMflv_4672-3e-1131.53% (111) TetR family transcriptional regulator
M. tuberculosis H37RvRv3208-6e-1128.06% (139) TetR family transcriptional regulator
M. leprae Br4923MLBr_00949-2e-2359.55% (89) hypothetical protein MLBr_00949
M. abscessus ATCC 19977MAB_4352c-2e-1133.33% (108) TetR family transcriptional regulator
M. marinum MMMAR_4335-9e-88100.00% (160) TetR family transcriptional regulator
M. avium 104MAV_4769-7e-1130.00% (120) transcriptional regulator, TetR family protein
M. smegmatis MC2 155MSMEG_1935-7e-1131.53% (111) TetR-family protein transcriptional regulator
M. thermoresistible (build 8)TH_0452-2e-1131.53% (111) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. vanbaalenii PYR-1Mvan_1795-1e-1031.53% (111) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mflv_4672|M.gilvum_PYR-GCK          MSELAKTAPRRGGQPANG----TGSSGAARRGNRLPRDERRGQLLAAASE
Mvan_1795|M.vanbaalenii_PYR-1       MSEVARTAQRRGGQPANG----ASPSGAARRGNRMPRDERRGQLLIAASE
MSMEG_1935|M.smegmatis_MC2_155      MSDLANTAERRGEK---------RPAGGNRRGNRLPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu      MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
Mb3233|M.bovis_AF2122/97            MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv         MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MUL_0145|M.ulcerans_Agy99           ----------------------MSTDSHGRRWAKTDATQRR--ILDAATE
MMAR_4335|M.marinum_M               ----------------------MSTDSHGRRWAKTDATQRR--ILDAATE
MLBr_00949|M.leprae_Br4923          ----------------------MTTSARTHRWAKTGAIQRR--ILDAAIE
MAB_4352c|M.abscessus_ATCC_199      --------------------------MVPLRQAQALATRQR--LVDVATE
MAV_4769|M.avium_104                ----------------MAVDYSELPAEEAVRAARAGARRRQ--VLDAAVK
                                                                  *  :    .::  :: .* .

Mflv_4672|M.gilvum_PYR-GCK          VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVS
Mvan_1795|M.vanbaalenii_PYR-1       VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKVELYLAVLQRHVDNLVS
MSMEG_1935|M.smegmatis_MC2_155      VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
TH_0452|M.thermoresistible__bu      VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
Mb3233|M.bovis_AF2122/97            VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv         VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MUL_0145|M.ulcerans_Agy99           VFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQMASAVEG
MMAR_4335|M.marinum_M               VFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQMASAVEG
MLBr_00949|M.leprae_Br4923          VFATRSFTTATMTDAMTGSGAIIGSIYHHFGGKRKLFLAIFEQMG-----
MAB_4352c|M.abscessus_ATCC_199      LFALHGFTSVTTTSLSEASGMTRGALYHHFANMTEVMEAVFERAEGFLVA
MAV_4769|M.avium_104                VMGRNGFHRMSMHDLAAEADVSVGLLYKYFGGKQDLLLATIVRILDVFRD
                                    ::  ..:      .    :.     :*::* .  .:  * : :       

Mflv_4672|M.gilvum_PYR-GCK          GVRQALRTTTDNRQR---VRAAVQAFFDFIEHDSQGYRLIFENDYVTEPQ
Mvan_1795|M.vanbaalenii_PYR-1       GVRQALRTTTDNRQR---VRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQ
MSMEG_1935|M.smegmatis_MC2_155      GVRQALRTTTDNRQR---LRAAVEAFFDFIEHDSQGYRLIFENDYVTEPQ
TH_0452|M.thermoresistible__bu      GVRQALRTTTDNRQR---LRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQ
Mb3233|M.bovis_AF2122/97            GVHQALSTTTDNRQR---LHVAVQAFFDFIEHDSQGYRLIFENDFVTEPE
Rv3208|M.tuberculosis_H37Rv         GVHQALSTTTDNRQR---LHVAVQAFFDFIEHDSQGYRLIFENDFVTEPE
MUL_0145|M.ulcerans_Agy99           KIEEALQQAGDETDRRRIFELGVRAYLDGLWEHRRVARLLASGDRPTDFG
MMAR_4335|M.marinum_M               KIEEALQQAGDETDRRRIFELGVRAYLDGLWEHRRVARLLASGDRPTDFG
MLBr_00949|M.leprae_Br4923          RQRRPPHRRGDATSG-PIRPSGDRS-AAGIRSPRTGPTSRRCGKTGTRPG
MAB_4352c|M.abscessus_ATCC_199      EVNHSLTSIESPAER---FLAIGSAVLDVLAREPIVQRIVFV-EAPMALG
MAV_4769|M.avium_104                QLAPVIDAAGDDVVD--QLSAGIRRYIQIVDENLDGVVLTYRESRTLGAA
                                              .                  :             .      

Mflv_4672|M.gilvum_PYR-GCK          VAAQVKVATESCTDAVFDLISHD----SGLEPHRARMIAVGLVSISVDSA
Mvan_1795|M.vanbaalenii_PYR-1       VAAQVKVATESCTDAVFDLISHD----SGLEPHRARMIAVGLVSISVDSA
MSMEG_1935|M.smegmatis_MC2_155      VAAQVKVATEACTDAVFDLISRD----SGLEAHRARMIAVGLVAISVDSA
TH_0452|M.thermoresistible__bu      VAAQVKVATEACTDAVFDLISQD----SGLEAHRARMIAVGLVAISVDCA
Mb3233|M.bovis_AF2122/97            VAAQVRVATESCIDAVFALISAD----SGLDPHRARMIAVGLVGMSVDCA
Rv3208|M.tuberculosis_H37Rv         VAAQVRVATESCIDAVFALISAD----SGLDPHRARMIAVGLVGMSVDCA
MUL_0145|M.ulcerans_Agy99           ITR-----RDRMTSAFRSWMAVL----ELDSSLHGQFLSRALLR------
MMAR_4335|M.marinum_M               ITR-----RDRMTSAFRSWMAVL----ELDSSLHGQFLSRALLAIMEESS
MLBr_00949|M.leprae_Br4923          CCR-----PETHLQASRSPVATA---------------------------
MAB_4352c|M.abscessus_ATCC_199      WSRWRALDGGRSLGLIQDILEELYRRGELVEAVDPQMAAQLILGAINESG
MAV_4769|M.avium_104                GRAQIKDLEIATAAPLRAVIETG-IAQGVFRSVDVDLAVFDIMLLAHGWA
                                                       :                              

Mflv_4672|M.gilvum_PYR-GCK          RYWLNNERPIDKDDAVEGTVQFIWGGLSHVPLTRS------
Mvan_1795|M.vanbaalenii_PYR-1       RYWLNNDRPIDKDDAVEGTVQFIWGGLSHVPMTRS------
MSMEG_1935|M.smegmatis_MC2_155      RYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS------
TH_0452|M.thermoresistible__bu      RYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS------
Mb3233|M.bovis_AF2122/97            RYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS------
Rv3208|M.tuberculosis_H37Rv         RYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS------
MUL_0145|M.ulcerans_Agy99           --------------------SWRSRH---------------
MMAR_4335|M.marinum_M               LMVAACEEPEQVKPVIDATIEWIGRLTE-------------
MLBr_00949|M.leprae_Br4923          -----------------------------------------
MAB_4352c|M.abscessus_ATCC_199      MYAAAAPSERSSRAAEQLTLLCRGLLSPRSG----------
MAV_4769|M.avium_104                LKHWHFGPIYTLDEYIALQTRHLLNGLISDERRADYADVLK