For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
MSTDSHGRRWAKTDATQRRILDAATEVFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQM ASAVEGKIEEALQQAGDETDRRRIFELGVRAYLDGLWEHRRVARLLASGDRPTDFGITRRDRMTSAFRSW MAVLELDSSLHGQFLSRALLAIMEESSLMVAACEEPEQVKPVIDATIEWIGRLTE
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4335 | - | - | 100% (195) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1350 | - | 2e-11 | 24.31% (181) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4631 | - | 8e-09 | 33.33% (75) | transcriptional regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 3e-11 | 23.20% (181) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4672 | - | 5e-12 | 25.27% (182) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 3e-11 | 23.20% (181) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00949 | - | 2e-23 | 59.55% (89) | hypothetical protein MLBr_00949 |
| M. abscessus ATCC 19977 | MAB_3527 | - | 1e-11 | 27.55% (196) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4769 | - | 9e-11 | 30.00% (120) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 5e-11 | 24.31% (181) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 1e-11 | 23.76% (181) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_0145 | - | 8e-88 | 100.00% (160) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1795 | - | 4e-11 | 24.73% (182) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4672|M.gilvum_PYR-GCK MSELAKTAPRRGGQPANGTGSS----GAARRGNRLPRDERRGQLLAAASE
Mvan_1795|M.vanbaalenii_PYR-1 MSEVARTAQRRGGQPANGASPS----GAARRGNRMPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MSMEG_1935|M.smegmatis_MC2_155 MSDLANTAERRGEKRPAG---------GNRRGNRLPRDERRGQLLIAASE
Mb3233|M.bovis_AF2122/97 MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MAB_3527|M.abscessus_ATCC_1997 MRDLAKLAGRRGTVNSTVATQDS-TQGNTRRGGRLPRDERRGQLVGSASE
MMAR_4335|M.marinum_M MSTDSHG----------------------RRWAKTDATQRR--ILDAATE
MUL_0145|M.ulcerans_Agy99 MSTDSHG----------------------RRWAKTDATQRR--ILDAATE
MLBr_00949|M.leprae_Br4923 MTTSART----------------------HRWAKTGAIQRR--ILDAAIE
MAV_4769|M.avium_104 MAVDYSELP------------------AEEAVRAARAGARRRQVLDAAVK
* . ** :: * .
Mflv_4672|M.gilvum_PYR-GCK VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVS
Mvan_1795|M.vanbaalenii_PYR-1 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKVELYLAVLQRHVDNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MSMEG_1935|M.smegmatis_MC2_155 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
Mb3233|M.bovis_AF2122/97 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MAB_3527|M.abscessus_ATCC_1997 IFVDRGYHAAGMDEIADRAGVSKPVLYQHFPSKLELYLAVLHKHADNLVS
MMAR_4335|M.marinum_M VFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQMASAVEG
MUL_0145|M.ulcerans_Agy99 VFATRGFNAATMAEVVASSGASIGSIYHHFGGKTELFLAIFEQMASAVEG
MLBr_00949|M.leprae_Br4923 VFATRSFTTATMTDAMTGSGAIIGSIYHHFGGKRKLFLAIFEQMG-----
MAV_4769|M.avium_104 VMGRNGFHRMSMHDLAAEADVSVGLLYKYFGGKQDLLLATIVRILDVFRD
:: ..: * : :.. :*::* .* .* ** : :
Mflv_4672|M.gilvum_PYR-GCK GVRQALRTTTDNRQR---VRAAVQAFFDFIEHDSQGYRLIFENDYVTEPQ
Mvan_1795|M.vanbaalenii_PYR-1 GVRQALRTTTDNRQR---VRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQ
TH_0452|M.thermoresistible__bu GVRQALRTTTDNRQR---LRAAVQAFFDFIEHDGQGYRLIFENDYVTEPQ
MSMEG_1935|M.smegmatis_MC2_155 GVRQALRTTTDNRQR---LRAAVEAFFDFIEHDSQGYRLIFENDYVTEPQ
Mb3233|M.bovis_AF2122/97 GVHQALSTTTDNRQR---LHVAVQAFFDFIEHDSQGYRLIFENDFVTEPE
Rv3208|M.tuberculosis_H37Rv GVHQALSTTTDNRQR---LHVAVQAFFDFIEHDSQGYRLIFENDFVTEPE
MAB_3527|M.abscessus_ATCC_1997 SVRQALRTTTDNRQR---LRAAVMAFFDFVEHDSQGYRLIFENDLVGVPQ
MMAR_4335|M.marinum_M KIEEALQQAGDETDRRRIFELGVRAYLDGLWEHRRVARLLASGDRPTDFG
MUL_0145|M.ulcerans_Agy99 KIEEALQQAGDETDRRRIFELGVRAYLDGLWEHRRVARLLASGDRPTDFG
MLBr_00949|M.leprae_Br4923 RQRRPPHRRGDATSG-PIRPSGDRS-AAGIRSPRTGPTSRRCGKTGTRPG
MAV_4769|M.avium_104 QLAPVIDAAGDDVVD--QLSAGIRRYIQIVDENLDGVVLTYRESRTLGAA
* . : .
Mflv_4672|M.gilvum_PYR-GCK VAAQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSA----
Mvan_1795|M.vanbaalenii_PYR-1 VAAQVKVATESCTDAVFDLISHDSGLEPHRARMIAVGLVSISVDSA----
TH_0452|M.thermoresistible__bu VAAQVKVATEACTDAVFDLISQDSGLEAHRARMIAVGLVAISVDCA----
MSMEG_1935|M.smegmatis_MC2_155 VAAQVKVATEACTDAVFDLISRDSGLEAHRARMIAVGLVAISVDSA----
Mb3233|M.bovis_AF2122/97 VAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCA----
Rv3208|M.tuberculosis_H37Rv VAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCA----
MAB_3527|M.abscessus_ATCC_1997 VSERVEGAISACTDAVFDLVSHDSGLDPHHARMVAVGLVGISQVSA----
MMAR_4335|M.marinum_M ITR-----RDRMTSAFRSWMAVLELDSSLHGQFLSRALLAIMEESS----
MUL_0145|M.ulcerans_Agy99 ITR-----RDRMTSAFRSWMAVLELDSSLHGQFLSRALLR----------
MLBr_00949|M.leprae_Br4923 CCR-----PETHLQASRSPVATA---------------------------
MAV_4769|M.avium_104 GRAQIKDLEIATAAPLRAVIETGIAQGVFRSVDVDLAVFDIMLLAHGWAL
. :
Mflv_4672|M.gilvum_PYR-GCK RYWLNNERPIDKDDAVEGTVQFIWGGLSHVPLTRS-----
Mvan_1795|M.vanbaalenii_PYR-1 RYWLNNDRPIDKDDAVEGTVQFIWGGLSHVPMTRS-----
TH_0452|M.thermoresistible__bu RYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS-----
MSMEG_1935|M.smegmatis_MC2_155 RYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS-----
Mb3233|M.bovis_AF2122/97 RYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS-----
Rv3208|M.tuberculosis_H37Rv RYWLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS-----
MAB_3527|M.abscessus_ATCC_1997 RYWLDNEKPISKDDAVNATVGFAWGGLSHVPLQPHG----
MMAR_4335|M.marinum_M LMVAACEEPEQVKPVIDATIEWIGRLTE------------
MUL_0145|M.ulcerans_Agy99 --------------------SWRSRH--------------
MLBr_00949|M.leprae_Br4923 ----------------------------------------
MAV_4769|M.avium_104 KHWHFGPIYTLDEYIALQTRHLLNGLISDERRADYADVLK