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M. smegmatis MC2 155 MSMEG_6009 (-)

annotation: transcriptional regulator, TetR family protein
coordinates: 6073484 - 6074101
length: 205

APDTPSQPASRRDELLQLAATMFADRGLKATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLRDFLDWLF
GRYQQILDTATSPLEKLTGLFMASFEAIEHRHAQVVIYQDEAKRLSDLPQFDFVETRNKEQRKMWVDILQ
EGVADGSFRPDLDVDLVYRFIRDTTWVSVRWYKPGGPLSAEQVGQQYLAIVLGGITQSQGDKHA*

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. smegmatis MC2 155 MSMEG_6009 - - 100% (205) transcriptional regulator, TetR family protein
M. smegmatis MC2 155 MSMEG_0712 - 4e-15 28.49% (186) transcriptional regulator, TetR family protein
M. smegmatis MC2 155 MSMEG_0120 - 5e-12 21.76% (193) transcriptional regulatory protein

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb3587c - 6e-86 76.44% (191) TetR family transcriptional regulator
M. gilvum PYR-GCK Mflv_1483 - 4e-91 81.91% (188) TetR family transcriptional regulator
M. tuberculosis H37Rv Rv3557c - 6e-86 76.44% (191) TetR family transcriptional regulator
M. leprae Br4923 MLBr_00815 - 5e-11 35.92% (103) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977 MAB_0599 - 2e-68 63.35% (191) TetR family transcriptional regulator
M. marinum M MMAR_5046 - 4e-84 76.29% (194) TetR family transcriptional regulator
M. avium 104 MAV_0603 - 6e-87 79.14% (187) transcriptional regulator, TetR family protein
M. thermoresistible (build 8) TH_2070 - 7e-87 77.72% (193) PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY
M. ulcerans Agy99 MUL_4120 - 3e-81 76.22% (185) TetR family transcriptional regulator
M. vanbaalenii PYR-1 Mvan_5283 - 5e-86 74.63% (205) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


MSMEG_6009|M.smegmatis_MC2_155      ----------------------------MAPDTPSQPASRRDELLQLAAT
Mflv_1483|M.gilvum_PYR-GCK          ----------------------------MDRALPS----RRDELLQLAAT
TH_2070|M.thermoresistible__bu      ----------------------------MTNSGPP---TRRDELLELAAQ
Mvan_5283|M.vanbaalenii_PYR-1       ----------------------------MSSGQAPQANTRRDELLQLAAT
Mb3587c|M.bovis_AF2122/97           -----------------------------MDRVAGQVNSRRGELLELAAA
Rv3557c|M.tuberculosis_H37Rv        -----------------------------MDRVAGQVNSRRGELLELAAA
MMAR_5046|M.marinum_M               -----------------------------MERMTGQANSRRGELLGLAAV
MUL_4120|M.ulcerans_Agy99           --------------------------------------------MGLAAV
MAV_0603|M.avium_104                --------------------------------MTGPANSRRDELLELAAA
MAB_0599|M.abscessus_ATCC_1997      -----------------MDKVSEVRESDALRAGGSPQPSRRDELLSLAAE
MLBr_00815|M.leprae_Br4923          MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
                                                                                : :*: 

MSMEG_6009|M.smegmatis_MC2_155      MFADRGLKATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLRDFLDWLFG
Mflv_1483|M.gilvum_PYR-GCK          MFADRGLRATTVRDIADSAGILSGSLYHHFKSKEQMVEEVLKDFLDWLFT
TH_2070|M.thermoresistible__bu      MFAERGLKATTVRDIADSAGILSGSLYHHFASKEEMVDEVLRGFLDWLFD
Mvan_5283|M.vanbaalenii_PYR-1       MFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRGFLDWLFD
Mb3587c|M.bovis_AF2122/97           MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFA
Rv3557c|M.tuberculosis_H37Rv        MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLDWLFA
MMAR_5046|M.marinum_M               MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLDWLFA
MUL_4120|M.ulcerans_Agy99           MFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLDWLFA
MAV_0603|M.avium_104                MFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLDWLFA
MAB_0599|M.abscessus_ATCC_1997      MFAERGLRATTVRDIADAAGILSGSLYHHFDSKEAIVDELLRDFLEGLFA
MLBr_00815|M.leprae_Br4923          VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
                                    :*.::* :*: : :*** **: .  **:** **  :   :*. .:: *. 

MSMEG_6009|M.smegmatis_MC2_155      RYQQILDTATSPLEKLTGLFMASFEAIEHRHAQVVIYQDEAKRLSDLPQF
Mflv_1483|M.gilvum_PYR-GCK          RYDEIVAATTDPLERVSGLFMVSFEAIEHRHAQVVIYQDEAKRLNSLPQF
TH_2070|M.thermoresistible__bu      RYRSIVETEPNPLERFKGLFMASFEAIEHRHAQVVIYQDEAKRLSSQPRF
Mvan_5283|M.vanbaalenii_PYR-1       RYQQIVATEPNPLERLKGLFMASFEAIETRHAEVVIYQDEAKRLSAQGRF
Mb3587c|M.bovis_AF2122/97           RYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRF
Rv3557c|M.tuberculosis_H37Rv        RYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLASQPRF
MMAR_5046|M.marinum_M               RYLEIVDGEPNPLERLKGLFLASFEAIEHRHAQVVIYQDEAQRLSSQPRF
MUL_4120|M.ulcerans_Agy99           RYLEIVDGEPNPLERLKGLFLASFEAIEHRHAQVVIYQDEAQRLSSQPRF
MAV_0603|M.avium_104                RYREIIDSESNPLERLKGLFMASFEAIEHRHAQVVIYQDEAKRLLSQPRF
MAB_0599|M.abscessus_ATCC_1997      RYREIAAANLNPVDTLKGLFLASFDAIETKHAQVAIYQAEAPRLLSQERF
MLBr_00815|M.leprae_Br4923          SVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDN--ITEPRV
                                       .      .  : . . . . *: **       :   :        :.

MSMEG_6009|M.smegmatis_MC2_155      DFVETRNKEQRKMWVDILQEGVADGSFRPDLDVDLVYRFIRDTTWVSVRW
Mflv_1483|M.gilvum_PYR-GCK          GFLDDRNRQQRRMWVEVLKQGIAEGSFRPDIDVDLVYRFIRDTTWVSVRW
TH_2070|M.thermoresistible__bu      AYVEQRNREQRKMWVDVLTQGIEEGYFRSDIDVDLVYRFIRDTTWVSVRW
Mvan_5283|M.vanbaalenii_PYR-1       AYVEERNKEQRKMWVDVLTQGIDEGYFRPDVDVDLVYRFIRDTTWVSVRW
Mb3587c|M.bovis_AF2122/97           SYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRW
Rv3557c|M.tuberculosis_H37Rv        SYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRW
MMAR_5046|M.marinum_M               SYLEDRNKEQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRW
MUL_4120|M.ulcerans_Agy99           SYLEDRNKEQRKMWLDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWVSVRW
MAV_0603|M.avium_104                SYIEDMNRQQRKMWLEVLNQGVDEGYFRPDLDVDLVYRFIRDTTWVSVRW
MAB_0599|M.abscessus_ATCC_1997      AYLNELNTEQRQLWLEVLRDGIAQGYFRPDLDVAVVYRFIRDATWVSVRW
MLBr_00815|M.leprae_Br4923          AAQVRVATESCIDAVFALIS--ADSRLDPHRARMVAVGLVGISVDCARYW
                                            :.    :  * .   :. : ..    :.  ::  :.  :  *

MSMEG_6009|M.smegmatis_MC2_155      YKPGGPLSAEQVGQQYLAIVLGGITQSQGDKHA---
Mflv_1483|M.gilvum_PYR-GCK          YQPGGPLTAEQVGRQYLAIVLGGITE--GSK-----
TH_2070|M.thermoresistible__bu      YRPGGPLTAEEVGRQYLSIVLGGITAGAN-------
Mvan_5283|M.vanbaalenii_PYR-1       YQPGGPLTAQQVGRQYLSIVLGGITAEPTSKESTNG
Mb3587c|M.bovis_AF2122/97           YRPGGPLTAQQVGQQYLAIVLGGITKEGV-------
Rv3557c|M.tuberculosis_H37Rv        YRPGGPLTAQQVGQQYLAIVLGGITKEGV-------
MMAR_5046|M.marinum_M               YKPGGALTAQQVGQKYLAIVLGGIQKEGV-------
MUL_4120|M.ulcerans_Agy99           YKPGGALTAQQVGQKYLAIVLGGIQKEGV-------
MAV_0603|M.avium_104                YQPGGPLTAEQVGQQYLAIVLGGITVDAKKD-----
MAB_0599|M.abscessus_ATCC_1997      FRPGGSRTAQEVAEQYLSIVLGGITVGSFSNSPEK-
MLBr_00815|M.leprae_Br4923          LDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----
                                      .. . : .:. .  : :. **:

species	id	gene	e-value	identity (len)	annotation
M. smegmatis MC2 155	MSMEG_6009	-	-	100% (205)	transcriptional regulator, TetR family protein
M. smegmatis MC2 155	MSMEG_0712	-	4e-15	28.49% (186)	transcriptional regulator, TetR family protein
M. smegmatis MC2 155	MSMEG_0120	-	5e-12	21.76% (193)	transcriptional regulatory protein