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TEAGAKPRRGRPPASDGDAAATRQRIMEVATDLFAEKGFHATGVAEIGAAAGVRGGALYYHIGSKEELLW EILRSYIDEMLTEAVHIANMNTEPARRLRTLIGSYVILIVKYRKQVAIQVRDGSALTGERAAQLQGLRDE LQRCWQRVFDEGHEVGTFHTADHVLTNAILGMLNMVAVWYRTDGKSPAQIAKRIADMVLDGIHVDRPEEH AEQAPTDRK*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4912c | - | - | 100% (220) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0599 | - | 1e-18 | 30.62% (209) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2061c | - | 3e-13 | 31.50% (127) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3587c | - | 7e-18 | 30.00% (190) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4599 | - | 3e-16 | 29.67% (182) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3557c | - | 8e-18 | 30.00% (190) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-08 | 30.12% (83) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_5046 | - | 2e-17 | 30.53% (190) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0603 | - | 2e-19 | 29.44% (197) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0712 | - | 5e-29 | 34.41% (186) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_2855 | - | 2e-17 | 29.28% (181) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4120 | - | 4e-16 | 30.90% (178) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5283 | - | 2e-16 | 29.26% (188) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3587c|M.bovis_AF2122/97 ---------------------------MDRVAGQVNSRR------GELLE
Rv3557c|M.tuberculosis_H37Rv ---------------------------MDRVAGQVNSRR------GELLE
MMAR_5046|M.marinum_M ---------------------------MERMTGQANSRR------GELLG
MUL_4120|M.ulcerans_Agy99 ------------------------------------------------MG
MAV_0603|M.avium_104 ------------------------------MTGPANSRR------DELLE
Mvan_5283|M.vanbaalenii_PYR-1 --------------------------MSSGQAPQANTRR------DELLQ
MAB_4912c|M.abscessus_ATCC_199 ---------------MTEAGAKPRRGRPPASDGDAAATR------QRIME
MSMEG_0712|M.smegmatis_MC2_155 ------------------------------MSKKFESNR------DEILR
TH_2855|M.thermoresistible__bu ---LSQSPDNATSSSRAGSGAGSGAGSGAEPIGRDTPRRRPRIRPEEIVS
Mflv_4599|M.gilvum_PYR-GCK ----------------------MNKVVVAGRTRVGGERR------ERILA
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKR----RGQLLI
:
Mb3587c|M.bovis_AF2122/97 LAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLD
Rv3557c|M.tuberculosis_H37Rv LAAAMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLRGFLD
MMAR_5046|M.marinum_M LAAVMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLD
MUL_4120|M.ulcerans_Agy99 LAAVMFAERGLRATTVRDIADGAGILSGSLYHHFASKEEMVDELLREFLD
MAV_0603|M.avium_104 LAAAMFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRSFLD
Mvan_5283|M.vanbaalenii_PYR-1 LAATMFAERGLRATTVRDIADSAGILSGSLYHHFSSKEEMVDEVLRGFLD
MAB_4912c|M.abscessus_ATCC_199 VATDLFAEKGFHATGVAEIGAAAGVRGGALYYHIGSKEELLWEILRSYID
MSMEG_0712|M.smegmatis_MC2_155 ISAELFAKSGYHGTGISDLGAAVGLGRGALYHYIGSKETILYEISSRQLA
TH_2855|M.thermoresistible__bu AAAEFFAREGYANVGMRDVAEAVGIRGASLYHHFGSKEEILYAICLTVTK
Mflv_4599|M.gilvum_PYR-GCK SATELIAERGYHAVSMADIGVASGVVGPAIYRHFNSKSDLLAALFERVVD
MLBr_00815|M.leprae_Br4923 VASDVFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMN
:: .:. * . : ::. *: :* :: ** : :
Mb3587c|M.bovis_AF2122/97 WLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLAS
Rv3557c|M.tuberculosis_H37Rv WLFARYRDIVDSTANPLERLQGLFMASFEAIEHHHAQVVIYQDEAQRLAS
MMAR_5046|M.marinum_M WLFARYLEIVDGEPNPLERLKGLFLASFEAIEHRHAQVVIYQDEAQRLSS
MUL_4120|M.ulcerans_Agy99 WLFARYLEIVDGEPNPLERLKGLFLASFEAIEHRHAQVVIYQDEAQRLSS
MAV_0603|M.avium_104 WLFARYREIIDSESNPLERLKGLFMASFEAIEHRHAQVVIYQDEAKRLLS
Mvan_5283|M.vanbaalenii_PYR-1 WLFDRYQQIVATEPNPLERLKGLFMASFEAIETRHAEVVIYQDEAKRLSA
MAB_4912c|M.abscessus_ATCC_199 EMLTEAVHIANMNTEPARRLRTLIGSYVILIVKYRKQVAIQVRDGSALTG
MSMEG_0712|M.smegmatis_MC2_155 QMNNLADELALTEKDPEKRLRGLARALLRNIAEHRAEWTVFFREYHALTG
TH_2855|M.thermoresistible__bu EPNELNLPLLDAAGTPAERLSALIRAHLEHLIRRRVEHLVALHDINSLTP
Mflv_4599|M.gilvum_PYR-GCK KLLKRATAIVEQSRDEAEALTLLVSDQVALVMDQRELAMVYYREVHNLSD
MLBr_00815|M.leprae_Br4923 NLVSSVQQALRTTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFEN----DN
. * . : : :
Mb3587c|M.bovis_AF2122/97 QPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWV
Rv3557c|M.tuberculosis_H37Rv QPRFSYIEDRNKQQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWV
MMAR_5046|M.marinum_M QPRFSYLEDRNKEQRKMWVDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWV
MUL_4120|M.ulcerans_Agy99 QPRFSYLEDRNKEQRKMWLDVLNQGIEEGYFRPDLDVDLVYRFIRDTTWV
MAV_0603|M.avium_104 QPRFSYIEDMNRQQRKMWLEVLNQGVDEGYFRPDLDVDLVYRFIRDTTWV
Mvan_5283|M.vanbaalenii_PYR-1 QGRFAYVEERNKEQRKMWVDVLTQGIDEGYFRPDVDVDLVYRFIRDTTWV
MAB_4912c|M.abscessus_ATCC_199 -ERAAQLQGLRDELQRCWQRVFDEGHEVGTFH--TADHVLTNAILGMLNM
MSMEG_0712|M.smegmatis_MC2_155 ERRDRVIAAR-ERYEAHWRNALDQGVRDGQFRP--LPTLMVKGLLGMFNY
TH_2855|M.thermoresistible__bu EHR-AIIDDLRRYYQRRVRDVIVAGVRSGEFDVP-DPKLAALLILDALNG
Mflv_4599|M.gilvum_PYR-GCK QHQSRLRRKQRLYLEEWVHLVGELRPAVDEIELRAMVHGAIGAIQSILHY
MLBr_00815|M.leprae_Br4923 ITEPRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDC
. . . . : :
Mb3587c|M.bovis_AF2122/97 SVRWYRPGGPLTAQQ-VGQQYLAIVLGGITKEGV--------------
Rv3557c|M.tuberculosis_H37Rv SVRWYRPGGPLTAQQ-VGQQYLAIVLGGITKEGV--------------
MMAR_5046|M.marinum_M SVRWYKPGGALTAQQ-VGQKYLAIVLGGIQKEGV--------------
MUL_4120|M.ulcerans_Agy99 SVRWYKPGGALTAQQ-VGQKYLAIVLGGIQKEGV--------------
MAV_0603|M.avium_104 SVRWYQPGGPLTAEQ-VGQQYLAIVLGGITVDAKKD------------
Mvan_5283|M.vanbaalenii_PYR-1 SVRWYQPGGPLTAQQ-VGRQYLSIVLGGITAEPTSKESTNG-------
MAB_4912c|M.abscessus_ATCC_199 VAVWYRTDG-KSPAQ-IAKRIADMVLDGIHVDRPEEHAEQAPTDRK--
MSMEG_0712|M.smegmatis_MC2_155 SYLWLTLDGPESPED-IADEFLDTVLVGMNADGLRS------------
TH_2855|M.thermoresistible__bu VSGWFHPDRGHSLPD-VIAAYTEMIVERVLRARIS-------------
Mflv_4599|M.gilvum_PYR-GCK RGTGLAPEQTSALLVAMGHAVLGVPASSHQVRGVNTEPSCPRPGTPQH
MLBr_00815|M.leprae_Br4923 ARYWLDTNRPISKSD-AVEGTVQFAWGGLSHVPLTRL-----------
: