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VSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHAL MAGEEEALRAHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLGGI YERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQLAHRRLNTDDNVTAAQVADFVVSLVLDGLRP RALAVGARGGRAART
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | - | 100% (225) | transcriptional regulator |
| M. bovis AF2122 / 97 | Mb3233 | - | 2e-12 | 27.08% (192) | TetR family transcriptional regulator |
| M. bovis AF2122 / 97 | Mb3587c | - | 3e-09 | 34.78% (115) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_4672 | - | 2e-12 | 28.02% (207) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 1e-122 | 100.00% (225) | transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 3e-12 | 27.60% (192) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4912c | - | 2e-11 | 26.89% (212) | TetR family transcriptional regulator |
| M. marinum M | MMAR_1350 | - | 2e-13 | 27.78% (198) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4155 | - | 2e-14 | 28.78% (205) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_1935 | - | 2e-12 | 28.12% (192) | TetR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_0452 | - | 4e-13 | 27.54% (207) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2529 | - | 2e-13 | 27.78% (198) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1795 | - | 7e-12 | 28.02% (207) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1561|M.bovis_AF2122/97 ---MSRASARRRRAVSDE-----------------DKSQRRDEILAAAKI
Rv1534|M.tuberculosis_H37Rv ---MSRASARRRRAVSDE-----------------DKSQRRDEILAAAKI
MMAR_1350|M.marinum_M MSDLAKAAQHRAVRSADRVRSTEGATP-KARGNRLPRDERRGQLLIVASD
MUL_2529|M.ulcerans_Agy99 MSDLAKAAQHRAVRSADRVRSTEGATP-KARGNRLPRDERRGQLLIVASD
MAV_4155|M.avium_104 MSELAKMPARRAVKSADRGRPTDGAAASNRRGNRLPRDERRGQLLVVASD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
Mflv_4672|M.gilvum_PYR-GCK MSELAKTAPRRGGQPANG----TGSSGAARRGNRLPRDERRGQLLAAASE
Mvan_1795|M.vanbaalenii_PYR-1 MSEVARTAQRRGGQPANG----ASPSGAARRGNRMPRDERRGQLLIAASE
MSMEG_1935|M.smegmatis_MC2_155 MSDLANTAERRGEK---------RPAGGNRRGNRLPRDERRGQLLIAASE
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MAB_4912c|M.abscessus_ATCC_199 MTEAGAKPRRGRPPASDG-----------------DAAATRQRIMEVATD
. . : * .:: .*.
Mb1561|M.bovis_AF2122/97 VFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRA
Rv1534|M.tuberculosis_H37Rv VFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRA
MMAR_1350|M.marinum_M VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
MUL_2529|M.ulcerans_Agy99 VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLNRHVDKLVA
MAV_4155|M.avium_104 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKLELYLAVLARHVENLVS
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
Mflv_4672|M.gilvum_PYR-GCK VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKVELYLAVLQRHVDNLVS
Mvan_1795|M.vanbaalenii_PYR-1 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFTSKVELYLAVLQRHVDNLVS
MSMEG_1935|M.smegmatis_MC2_155 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MAB_4912c|M.abscessus_ATCC_199 LFAEKGFHATGVAEIGAAAGVRGGALYYHIGSKEELLWEILRSYIDEMLT
:*..:*:**: : :*. **: :* :: ** :* :: : : :
Mb1561|M.bovis_AF2122/97 HVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALG
Rv1534|M.tuberculosis_H37Rv HVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALG
MMAR_1350|M.marinum_M GVQQALR-----TTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTE
MUL_2529|M.ulcerans_Agy99 GVQQALR-----TTTDNRGRLYAAVQAFFDFIEHDSQGYRLIFENDYVTE
MAV_4155|M.avium_104 GVQQALS-----TTKDNRRRLHAAVQAFFDFIEHDSQGYRLIFENDYVTE
MLBr_00815|M.leprae_Br4923 SVQQALR-----TTTNNRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITE
Mflv_4672|M.gilvum_PYR-GCK GVRQALR-----TTTDNRQRVRAAVQAFFDFIEHDSQGYRLIFENDYVTE
Mvan_1795|M.vanbaalenii_PYR-1 GVRQALR-----TTTDNRQRVRAAVQAFFDFIEHDGQGYRLIFENDYVTE
MSMEG_1935|M.smegmatis_MC2_155 GVRQALR-----TTTDNRQRLRAAVEAFFDFIEHDSQGYRLIFENDYVTE
TH_0452|M.thermoresistible__bu GVRQALR-----TTTDNRQRLRAAVQAFFDFIEHDGQGYRLIFENDYVTE
MAB_4912c|M.abscessus_ATCC_199 EAVHIAN-----MNTEPARRLRTLIGSYVILIVKYRKQVAIQVRDGSALT
. : : : : . :: : ..:
Mb1561|M.bovis_AF2122/97 GRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQL
Rv1534|M.tuberculosis_H37Rv GRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAALVGQL
MMAR_1350|M.marinum_M PEVAAQVRVATESCIDAVFALISADSG---LDPHRARMIAVALVSMSVDC
MUL_2529|M.ulcerans_Agy99 PEVAAQVRVATESCIDAVFALISADSG---LDPHRARMIAVALVSMSVDC
MAV_4155|M.avium_104 PEVAAQVRVATESCIDAVYALISEDSG---LDPHRARMIAVGLVGISVDC
MLBr_00815|M.leprae_Br4923 PRVAAQVRVATESCIDAVFALISADSR---LDPHRARMVAVGLVGISVDC
Mflv_4672|M.gilvum_PYR-GCK PQVAAQVKVATESCTDAVFDLISHDSG---LEPHRARMIAVGLVSISVDS
Mvan_1795|M.vanbaalenii_PYR-1 PQVAAQVKVATESCTDAVFDLISHDSG---LEPHRARMIAVGLVSISVDS
MSMEG_1935|M.smegmatis_MC2_155 PQVAAQVKVATEACTDAVFDLISRDSG---LEAHRARMIAVGLVAISVDS
TH_0452|M.thermoresistible__bu PQVAAQVKVATEACTDAVFDLISQDSG---LEAHRARMIAVGLVAISVDC
MAB_4912c|M.abscessus_ATCC_199 GERAAQLQGLRDELQRCWQRVFDEGHEVG-TFHTADHVLTNAILGMLNMV
. :: : :. :: : : .:
Mb1561|M.bovis_AF2122/97 AHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
Rv1534|M.tuberculosis_H37Rv AHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
MMAR_1350|M.marinum_M ARYWLDSDRPISKSDAIEGTVQFAWGGLSHVPLARS---------
MUL_2529|M.ulcerans_Agy99 ARYWLDSDRPISKSDAIEGTVQFAWGGLSHVPLARS---------
MAV_4155|M.avium_104 ARYWLDSDRPISKADAVEGTVAFAWGGLSHVPLTRS---------
MLBr_00815|M.leprae_Br4923 ARYWLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL---------
Mflv_4672|M.gilvum_PYR-GCK ARYWLNNERPIDKDDAVEGTVQFIWGGLSHVPLTRS---------
Mvan_1795|M.vanbaalenii_PYR-1 ARYWLNNDRPIDKDDAVEGTVQFIWGGLSHVPMTRS---------
MSMEG_1935|M.smegmatis_MC2_155 ARYWLNNDRPIDKDSAVEGTVQFAWGGLSHVPLTRS---------
TH_0452|M.thermoresistible__bu ARYWLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS---------
MAB_4912c|M.abscessus_ATCC_199 AVWYRTDGK--SPAQIAKRIADMVLDGIHVDRPEEHAEQAPTDRK
* . . . : .*: