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VVASPRNTEADRGQRRATFQRANSHTTKQMLVHAAMALWRTNGYANTTVAEICRGAGVSKALFYFYFPRK EDVLFEVGVMSTRSAQRTIAKLLADDYDVMTVVGAALTALERSMSSNPRELVIETILEGYRHEHRLLATG ENRPDLDGGMFTTLFARAVADGKLPAGTDTDRLAHLAMMMVSEGARHWAAGAFGARSFADVVASDIATLI AGSTGRRRP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4825 | - | - | 100% (219) | transcriptional repressor, TetR family protein, putative |
| M. smegmatis MC2 155 | MSMEG_6441 | - | 3e-07 | 34.21% (76) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6604 | - | 4e-07 | 27.08% (144) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 4e-05 | 33.33% (87) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_2452 | - | 2e-74 | 67.98% (203) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 4e-05 | 33.33% (87) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_01070 | - | 5e-06 | 32.22% (90) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4027 | - | 4e-07 | 25.48% (157) | TetR/AcrR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 4e-06 | 29.31% (116) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2657 | - | 2e-08 | 26.17% (214) | transcriptional regulator |
| M. thermoresistible (build 8) | TH_0258 | - | 5e-75 | 65.88% (211) | transcriptional repressor, TetR family protein, putative |
| M. ulcerans Agy99 | MUL_4864 | - | 3e-06 | 29.31% (116) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4199 | - | 1e-81 | 69.59% (217) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2452|M.gilvum_PYR-GCK ------------MSPS---RQP----------------------------
Mvan_4199|M.vanbaalenii_PYR-1 MPHKPGREERRQLEPSGDERQQGEHQRGGPQHTHATHSAEDDLQVPIVRL
TH_0258|M.thermoresistible__bu --------------------------------------------------
MSMEG_4825|M.smegmatis_MC2_155 --------------------------------------------------
MMAR_0249|M.marinum_M --------------------------------------------------
MUL_4864|M.ulcerans_Agy99 --------------------------------------------------
Mb3885|M.bovis_AF2122/97 --------------------------------------------------
Rv3855|M.tuberculosis_H37Rv --------------------------------------------------
MLBr_01070|M.leprae_Br4923 --------------------------------------------------
MAB_4027|M.abscessus_ATCC_1997 --------------------------------------------------
MAV_2657|M.avium_104 --------------------------------------------------
Mflv_2452|M.gilvum_PYR-GCK ---------AMFRHMPDAKNP-MAADRGQRRASFQRADSRETQRTLIQAA
Mvan_4199|M.vanbaalenii_PYR-1 RSTIGSHDFACYLHDVAATRPDTQPDHGQRRASFQRARSRETKRMLVQAA
TH_0258|M.thermoresistible__bu ---------------------VSRADGGQRRASYQRARSRETKRALVQAA
MSMEG_4825|M.smegmatis_MC2_155 ---------------MVASPRNTEADRGQRRATFQRANSHTTKQMLVHAA
MMAR_0249|M.marinum_M -----------------MGSTASTTAPHSPQQKVREAQRLRTRARVFDAA
MUL_4864|M.ulcerans_Agy99 -----------------MGSTASTTAAHSPQQKVREAQRLRTRARVFDAA
Mb3885|M.bovis_AF2122/97 --------------MTTSAASQASLP---RGRRTARPSGDDRELAILATA
Rv3855|M.tuberculosis_H37Rv --------------MTTSAASQASLP---RGRRTARPSGDDRELAILATA
MLBr_01070|M.leprae_Br4923 -------------MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVA
MAB_4027|M.abscessus_ATCC_1997 -------------------MASTSSGRRGPGRPPNPARARERQRALTEAA
MAV_2657|M.avium_104 --------------------------MARGDRSPRDAHADRVRNALLNAA
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Mflv_2452|M.gilvum_PYR-GCK MALWRTKGYAATTVADICTAAGVSKALFYFYFPRKEDVLFEVGVLSTKAA
Mvan_4199|M.vanbaalenii_PYR-1 MALWRTKGYATTTVADICTAAGVSKALFYFYFPRKEDVLFEVGVLSTQSA
TH_0258|M.thermoresistible__bu MALWRTNGYANTTVADICRAAGVSRALFYFYFPAKEDILFEVGLLSTQAA
MSMEG_4825|M.smegmatis_MC2_155 MALWRTNGYANTTVAEICRGAGVSKALFYFYFPRKEDVLFEVGVMSTRSA
MMAR_0249|M.marinum_M VAEIGRRGLAGADVAAIAAAAGVARGTFYFHFPTKEHVLVELERAEELAI
MUL_4864|M.ulcerans_Agy99 VAEIGRRGLAGADVAAIAAAAGVARGTFYFHFPTKEHVLVELERAEELAI
Mb3885|M.bovis_AF2122/97 ENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQA
Rv3855|M.tuberculosis_H37Rv ENLLEDRPLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQA
MLBr_01070|M.leprae_Br4923 ERLLAERPLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKS
MAB_4027|M.abscessus_ATCC_1997 ALEFAEKGYHKASITDITQRAGVGRGTFYLYFDTKRDVLDAVIDSYFQRT
MAV_2657|M.avium_104 LNLFSTNGYDETTTDQIAESVGVSPRTFFRYFPTKESVLFFGEYDFIDAV
. : .*:. *: :* *. :*
Mflv_2452|M.gilvum_PYR-GCK HRRIHALLKKPYEIESVIAGALTAFEQSMARNPK-DLVIETILEGYRHEH
Mvan_4199|M.vanbaalenii_PYR-1 HRTIHALLKKPYEIESVVSAALTAFERSMARNPR-ELIIETILEGYRHEH
TH_0258|M.thermoresistible__bu RRRIRSLLRGDYDVDSVIAAALRSLERSMARNPR-ELIVQTILEGYRHEH
MSMEG_4825|M.smegmatis_MC2_155 QRTIAKLLADDYDVMTVVGAALTALERSMSSNPR-ELVIETILEGYRHEH
MMAR_0249|M.marinum_M VAKLRDPTADPTDLVSVLS-SLVHQVVAVERRLG-PVVFRDMLGLHFAPT
MUL_4864|M.ulcerans_Agy99 VAKLRDPTADSTDLVSVLS-SLAHQVVAVERRLG-PLVFRDMLGLHFAPT
Mb3885|M.bovis_AF2122/97 DMALQTLAENPADTDRENMWRTGINVFFETFGSH-KAVTRAGQAARATSV
Rv3855|M.tuberculosis_H37Rv DMALQTLAENPADTDRENMWRTGINVFFETFGSH-KAVTRAGQAARATSV
MLBr_01070|M.leprae_Br4923 RSAVEALAEQLP-ADPAAVWRSAITAFFEVCGTH-RAVAVAGAAAKATSP
MAB_4027|M.abscessus_ATCC_1997 VAAVNDTSDLLGNASDFELHLRTVFTRLFDMLDNSPEIMQVILREGLLDT
MAV_2657|M.avium_104 SGVYLAQPEEASDFEALANSFALLAPGLKRIRKR----IAQYHDAVASSL
Mflv_2452|M.gilvum_PYR-GCK RLMAGGGH-PDPDADMFTELFTRARDDGKLPASVDPVHLAYLAQTMVSEG
Mvan_4199|M.vanbaalenii_PYR-1 RIMADGSP-PDVDADMFTELFTRARSDGKLPGTVDTAHLAYLAQTMVSEG
TH_0258|M.thermoresistible__bu RILAGEED-PATGADMFGELFTRAQQDGKLAAGIDVDHLSRVAQMLVSEG
MSMEG_4825|M.smegmatis_MC2_155 RLLATGENRPDLDGGMFTTLFARAVADGKLPAGTDTDRLAHLAMMMVSEG
MMAR_0249|M.marinum_M RPVEDQLG-EHPLAEFVIETIARAQRANRVPPDADAGELG---VIFLTGL
MUL_4864|M.ulcerans_Agy99 RPVEDQLG-EHPLAEFVIETIAQAQRADRVAPDADAGELG---VIFLTGL
Mb3885|M.bovis_AF2122/97 EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERT
Rv3855|M.tuberculosis_H37Rv EVAELWSTFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERT
MLBr_01070|M.leprae_Br4923 EVRRLWSTVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERV
MAB_4027|M.abscessus_ATCC_1997 AMTKRMFGILDLIEAINVTIIEQAVMDGAITAAVDIPFLAHAITGLSMAA
MAV_2657|M.avium_104 VLLGRERKNHEANAETVAQVIAERRR--MPAPDSECRLLAAVGMLLVERA
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Mflv_2452|M.gilvum_PYR-GCK SRHWAAGAFGDRSFAEVVTGDICTLVNGY---------RHTP
Mvan_4199|M.vanbaalenii_PYR-1 ARHWAAGAFGSRSFAEVVTADICTLVNGYTARRPHVEFRDRP
TH_0258|M.thermoresistible__bu VRHWAAGGFGDRSFTEVVAGDIAALIDGYN-------LRLRR
MSMEG_4825|M.smegmatis_MC2_155 ARHWAAGAFGARSFADVVASDIATLIAGSTG-------RRRP
MMAR_0249|M.marinum_M FALLATGATTPDARTALLNRFVTTVVHGMEAR----------
MUL_4864|M.ulcerans_Agy99 FALLATGATTPDARTALLNGFVTTVVHGMEAR----------
Mb3885|M.bovis_AF2122/97 LFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR--------
Rv3855|M.tuberculosis_H37Rv LFASFAGEQPSVPEARVLDTLVHIWVTSIYGENR--------
MLBr_01070|M.leprae_Br4923 MAATFSDEKPLIPDKKVIDTLVHIWLASIYGS----------
MAB_4027|M.abscessus_ATCC_1997 TLKAIRGELEGDAREAYIGSFIQLVRTATTGSTPVANS----
MAV_2657|M.avium_104 LNQWLS--TPGRSLDDLIRQEFAALPAVLK------------
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