For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
VTTASQTRTPRGRRSARPSGDDREAAILATAQRLLETKKFAEISVDDLAKGAGISRPTFYFYFPSKEAVL LSLIDPLIKRADSGFDNAVESMPADPQRAIRRGIEIFFNSFGSHPATARAGTEALKSSPEFKEFWSGLMQ KWIAATAALITAERERGAAPDTIPALDLATSLNLMNERTMMAALADEQPGVAPEKVVATLTHIWLNSIYG TLPVGTA
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6441 | - | - | 100% (217) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1967 | - | 2e-21 | 33.33% (201) | TetR-family protein transcriptional regulator |
| M. smegmatis MC2 155 | MSMEG_3874 | - | 5e-19 | 26.85% (216) | transcriptional regulator, TetR family protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 9e-69 | 62.56% (211) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_0963 | - | 3e-61 | 56.40% (211) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 9e-69 | 62.56% (211) | transcriptional regulatory repressor protein (TETR-family) |
| M. leprae Br4923 | MLBr_00064 | - | 2e-60 | 54.03% (211) | putative transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0984c | - | 3e-51 | 50.74% (203) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5405 | ethR | 7e-67 | 59.81% (209) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0173 | - | 2e-81 | 70.95% (210) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1150 | - | 2e-64 | 60.28% (214) | TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR |
| M. ulcerans Agy99 | MUL_5027 | ethR | 7e-67 | 59.33% (209) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5684 | - | 1e-58 | 53.33% (210) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6441|M.smegmatis_MC2_155 -MTTASQTRTP-----------RGRRSARPSGDDREAAILATAQRLLETK
MAV_0173|M.avium_104 -MTTAGQTRAL-----------RGRRAIRPTGDEREQAILATALRLLETR
Mb3885|M.bovis_AF2122/97 -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
Rv3855|M.tuberculosis_H37Rv -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
MLBr_00064|M.leprae_Br4923 -MINSTAGQTS---------QSRSRRSTRPSGDDRELAILATAEQLLEDR
MMAR_5405|M.marinum_M MVSTSTASQAS---------PSRGRRSARPSGDERELAILNTAEKLLEDR
MUL_5027|M.ulcerans_Agy99 -MSTSTASQAS---------LSRGRRSARPSGDERELAILNTAEKLLEDR
Mvan_5684|M.vanbaalenii_PYR-1 -MRSSTRCKVSPVTATSPTRPARGRRAARPSGDDRELAILETAERLLADR
Mflv_0963|M.gilvum_PYR-GCK -MSSTTRTG-------------RGRRAARPSGDDRESAILTTAEQLLEQR
TH_1150|M.thermoresistible__bu -MSTASPVRS------------RGRRSTRPSGDDRELAILTTAEKLLAER
MAB_0984c|M.abscessus_ATCC_199 -MTKPAT---------------RGRKTTRPSGDERIQAILATAEELLGKR
: .. *.*:: **:**:* *** ** .** :
MSMEG_6441|M.smegmatis_MC2_155 KFAEISVDDLAKGAGISRPTFYFYFPSKEAVLLSLIDPLIKRADSGFDNA
MAV_0173|M.avium_104 PFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLEPVIARADAEFDGA
Mb3885|M.bovis_AF2122/97 PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
Rv3855|M.tuberculosis_H37Rv PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
MLBr_00064|M.leprae_Br4923 PLTEISVDYLAKSAGISRPTFYFYFASKEAVLLTLLDRVFNKANAALETL
MMAR_5405|M.marinum_M PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
MUL_5027|M.ulcerans_Agy99 PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
Mvan_5684|M.vanbaalenii_PYR-1 SLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALAQL
Mflv_0963|M.gilvum_PYR-GCK PLNDISVDDLARGAGISRPTFYFYFSSKDAVLLALLDRVIAEANARADAA
TH_1150|M.thermoresistible__bu PLAEISVDDLAKGAGLSRPTFYFYFPSKDAVLLALVERVIAEADQRADAA
MAB_0984c|M.abscessus_ATCC_199 PLADVSVDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVASI
: :*** **:.**:********* **::*:*:* : :. .*:
MSMEG_6441|M.smegmatis_MC2_155 VES---MPADPQRAIRRGIEIFFNSFGSHPATARAGTEALKSSPEFKEFW
MAV_0173|M.avium_104 VQR---LPTDPRRVWRNGIKAFFTAFSSHRALARAATEALATSSELRSVW
Mb3885|M.bovis_AF2122/97 AENP--ADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELW
Rv3855|M.tuberculosis_H37Rv AENP--ADTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELW
MLBr_00064|M.leprae_Br4923 IKN---RDNKRGNKWRTGINVFFETFGSHKAVTCAGQVTRDN-TEVRKLW
MMAR_5405|M.marinum_M AQA---PDVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISAEVRELW
MUL_5027|M.ulcerans_Agy99 AQA---PDVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRELW
Mvan_5684|M.vanbaalenii_PYR-1 IAE---RSSDRRTIWRRGINVFFETFGAHRAVCATTVGVKSTNSEARELW
Mflv_0963|M.gilvum_PYR-GCK LGGRDDRPLEPAGVWQ-AIKALFETFAAHRAVMLAGAAMRPNNPEVQRVW
TH_1150|M.thermoresistible__bu LNGMDARAVDPAGVWR-AINALFETFGAHRAVTLAGAAARTTNTEVDALW
MAB_0984c|M.abscessus_ATCC_199 DPA---AMTSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQRW
. : *: * :*.:* * * *
MSMEG_6441|M.smegmatis_MC2_155 SGLMQKWIAATAALITAERERGAAPDTIPALDLATSLNLMNERTMMAALA
MAV_0173|M.avium_104 SGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALS
Mb3885|M.bovis_AF2122/97 STFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFA
Rv3855|M.tuberculosis_H37Rv STFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFA
MLBr_00064|M.leprae_Br4923 STFMQKWISYTAAVIDAERKRGVAPDTLPATELATALNLMNERALFASFT
MMAR_5405|M.marinum_M STFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFL
MUL_5027|M.ulcerans_Agy99 STFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFL
Mvan_5684|M.vanbaalenii_PYR-1 SRSMQRWIDHIAAVIEAERADGAAPVTVPARELSTALNLMNESVMTATFT
Mflv_0963|M.gilvum_PYR-GCK SHFMQKWIDYTAASIRAERERGAAPDTLPAEDLAIALNLMNERIMLSAFA
TH_1150|M.thermoresistible__bu SRFMKKWIDYTAESIRAERERGAAPDTIPAEDLAVSLNLMNERTMFAAFA
MAB_0984c|M.abscessus_ATCC_199 SEVTENWVANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRATFT
* :.*: : * *** *.** .:** ::: :** :*: : :::
MSMEG_6441|M.smegmatis_MC2_155 DEQPGVAPEKVVATLTHIWLNSIYGTLPVGTA
MAV_0173|M.avium_104 AETPAVAEDRVVDTLTHIWVSSIYGESG----
Mb3885|M.bovis_AF2122/97 GEQPSVPEARVLDTLVHIWVTSIYGENR----
Rv3855|M.tuberculosis_H37Rv GEQPSVPEARVLDTLVHIWVTSIYGENR----
MLBr_00064|M.leprae_Br4923 AEQPHVPESRVLDTLVHIWVSSIYNEIR----
MMAR_5405|M.marinum_M AEEPSVPETHVVDTLVHIWVSSIYGEAR----
MUL_5027|M.ulcerans_Agy99 AEEPSVPETHVVDTLVHVWVSSIYGAAR----
Mvan_5684|M.vanbaalenii_PYR-1 GHQPAIPDDRVLDNLVHIWTTSIYGKTD----
Mflv_0963|M.gilvum_PYR-GCK SEQAAVTADRLVGTLAHIWVSSIYGTPRA---
TH_1150|M.thermoresistible__bu DEKPAVPEDRIVDTLAHIWLTSIYGTGR----
MAB_0984c|M.abscessus_ATCC_199 GQQPAVDDGKVVDTLLHVWLNAIYGGVCANS-
. . : ::: .* *:* .:**.