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M. thermoresistible (build 8) TH_0258 (-)

annotation: transcriptional repressor, TetR family protein, putative
coordinates: 566535 - 567173
length: 213

aa seq not available

Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. thermoresistible (build 8)TH_0258--100% (213)transcriptional repressor, TetR family protein, putative
M. thermoresistible (build 8)TH_3524-6e-1135.51% (107) PUTATIVE -
M. thermoresistible (build 8)TH_1791-2e-0932.29% (96) transcriptional regulator, TetR family protein

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1561-6e-0733.33% (87) transcriptional regulator
M. gilvum PYR-GCKMflv_2452-5e-8069.46% (203) TetR family transcriptional regulator
M. tuberculosis H37RvRv1534-6e-0733.33% (87) transcriptional regulator
M. leprae Br4923MLBr_02677-4e-0530.97% (113) putative TetR-family transcriptional regulator
M. abscessus ATCC 19977MAB_4027-2e-0929.09% (165) TetR/AcrR family transcriptional regulator
M. marinum MMMAR_1492-1e-0849.06% (53) transcriptional regulatory protein
M. avium 104MAV_1952-1e-0926.78% (183) transcriptional regulator
M. smegmatis MC2 155MSMEG_4825-7e-7565.88% (211) transcriptional repressor, TetR family protein, putative
M. ulcerans Agy99MUL_2448-2e-0847.17% (53) transcriptional regulatory protein
M. vanbaalenii PYR-1Mvan_4199-1e-8068.75% (208) TetR family transcriptional regulator

CLUSTAL 2.0.9 multiple sequence alignment


Mb1561|M.bovis_AF2122/97            --------------------------------------------------
Rv1534|M.tuberculosis_H37Rv         --------------------------------------------------
Mflv_2452|M.gilvum_PYR-GCK          ------------MSPS---RQP----------------------------
Mvan_4199|M.vanbaalenii_PYR-1       MPHKPGREERRQLEPSGDERQQGEHQRGGPQHTHATHSAEDDLQVPIVRL
TH_0258|M.thermoresistible__bu      --------------------------------------------------
MSMEG_4825|M.smegmatis_MC2_155      --------------------------------------------------
MMAR_1492|M.marinum_M               --------------------------------------------------
MUL_2448|M.ulcerans_Agy99           --------------------------------------------------
MAV_1952|M.avium_104                --------------------------------------------------
MAB_4027|M.abscessus_ATCC_1997      --------------------------------------------------
MLBr_02677|M.leprae_Br4923          --------------------------------------------------
                                                                                      

Mb1561|M.bovis_AF2122/97            ----------------------MSRASARRRRAVSDEDKSQRRDEILAAA
Rv1534|M.tuberculosis_H37Rv         ----------------------MSRASARRRRAVSDEDKSQRRDEILAAA
Mflv_2452|M.gilvum_PYR-GCK          ---------AMFRHMPDAKNP-MAADRGQRRASFQRADSRETQRTLIQAA
Mvan_4199|M.vanbaalenii_PYR-1       RSTIGSHDFACYLHDVAATRPDTQPDHGQRRASFQRARSRETKRMLVQAA
TH_0258|M.thermoresistible__bu      ---------------------VSRADGGQRRASYQRARSRETKRALVQAA
MSMEG_4825|M.smegmatis_MC2_155      ---------------MVASPRNTEADRGQRRATFQRANSHTTKQMLVHAA
MMAR_1492|M.marinum_M               -----------------------MPARQESRE--LSSKGRQTRQAIEQAA
MUL_2448|M.ulcerans_Agy99           -----------------------MPARQESRE--LSSKGRQTRQAIEQVA
MAV_1952|M.avium_104                ----------------------------------------------MDAA
MAB_4027|M.abscessus_ATCC_1997      -------------------MASTSSGRRGPGRPPNPARARERQRALTEAA
MLBr_02677|M.leprae_Br4923          ---------------------------MESQRRTQEERSTATRDALTLAR
                                                                                    . 

Mb1561|M.bovis_AF2122/97            KIVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEE-A
Rv1534|M.tuberculosis_H37Rv         KIVFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEE-A
Mflv_2452|M.gilvum_PYR-GCK          MALWRTKGYAATTVADICTAAGVSKALFYFYFPRKEDVLFEVG------V
Mvan_4199|M.vanbaalenii_PYR-1       MALWRTKGYATTTVADICTAAGVSKALFYFYFPRKEDVLFEVG------V
TH_0258|M.thermoresistible__bu      MALWRTNGYANTTVADICRAAGVSRALFYFYFPAKEDILFEVG------L
MSMEG_4825|M.smegmatis_MC2_155      MALWRTNGYANTTVAEICRGAGVSKALFYFYFPRKEDVLFEVG------V
MMAR_1492|M.marinum_M               RKLFAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQS----F
MUL_2448|M.ulcerans_Agy99           RKLFAERGFHGTTLADITSAAGKSSAVFYRYFTDKEDLLAALAQS----F
MAV_1952|M.avium_104                LNLFSANGYDQTTTDEIAEAAGVSPRTFFRYFPTKESVLFFGEYD----F
MAB_4027|M.abscessus_ATCC_1997      ALEFAEKGYHKASITDITQRAGVGRGTFYLYFDTKRDVLDAVIDS--Y-F
MLBr_02677|M.leprae_Br4923          HRLWRLRGYAEVGTPEIAKEADTTRGAVYHQFTDKAALFRDVVETVEQDA
                                       :  .*:  .   :*   *.     .:  *  *  ::           

Mb1561|M.bovis_AF2122/97            LRAHVAAELARVGGSTEAPLRALLQAAVQATFEFFETD-KATVKLLFRDA
Rv1534|M.tuberculosis_H37Rv         LRAHVAAELARVGGSTEAPLRALLQAAVQATFEFFETD-KATVKLLFRDA
Mflv_2452|M.gilvum_PYR-GCK          LSTKAAHRRIHALLKKPYEIESVIAGALTAFEQSMARNPKDLVIETILEG
Mvan_4199|M.vanbaalenii_PYR-1       LSTQSAHRTIHALLKKPYEIESVVSAALTAFERSMARNPRELIIETILEG
TH_0258|M.thermoresistible__bu      LSTQAARRRIRSLLRGDYDVDSVIAAALRSLERSMARNPRELIVQTILEG
MSMEG_4825|M.smegmatis_MC2_155      MSTRSAQRTIAKLLADDYDVMTVVGAALTALERSMSSNPRELVIETILEG
MMAR_1492|M.marinum_M               LHDVVTPSGVSLQLPDSPDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAA
MUL_2448|M.ulcerans_Agy99           LHDVVTPSGVSLQLPDSPDDDTFFTAVVTGYWNIFKQNIGIMIAVDQLAA
MAV_1952|M.avium_104                IHAFSAVYLGRDESLSDYEAMSEAFAVLAPSLKRIRKR-----IAQYHEA
MAB_4027|M.abscessus_ATCC_1997      QRTVAAVNDTSDLLGNASDFELHLRTVFTRLFDMLDNS--PEIMQVILRE
MLBr_02677|M.leprae_Br4923          MAQIASVVASSGAKTPVDAIRAKVDAWLEGLADPQVRQLILLYAPSVLGW
                                         :                     .                      

Mb1561|M.bovis_AF2122/97            YALGGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAAL
Rv1534|M.tuberculosis_H37Rv         YALGGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVVEAPSRMAAYTLAAL
Mflv_2452|M.gilvum_PYR-GCK          YRHEHRLMAGGGH-PDPDADMFTELFTRARDDGK---LPASVDPVHLAYL
Mvan_4199|M.vanbaalenii_PYR-1       YRHEHRIMADGSP-PDVDADMFTELFTRARSDGK---LPGTVDTAHLAYL
TH_0258|M.thermoresistible__bu      YRHEHRILAGEED-PATGADMFGELFTRAQQDGK---LAAGIDVDHLSRV
MSMEG_4825|M.smegmatis_MC2_155      YRHEHRLLATGENRPDLDGGMFTTLFARAVADGK---LPAGTDTDRLAHL
MMAR_1492|M.marinum_M               T--QQRFAAVQNQFRRFGMDIIAASVRHAQDQGYGTELNPDHTAVAIALL
MUL_2448|M.ulcerans_Agy99           T--QQRFAAVQNQFRRFGMDIIAASVRHAQDQGYGTELNPDHTAVAIALL
MAV_1952|M.avium_104                VASSLVLLGRERRNHEANRETVAKVIAERR------GLPAPDGECWLLAS
MAB_4027|M.abscessus_ATCC_1997      GLLDTAMTKRMFGILDLIEAINVTIIEQAVMDGA---ITAAVDIPFLAHA
MLBr_02677|M.leprae_Br4923          AAFRDVAQHYSLGMTEQQLLSEASRARQLAQPLDHVLIGKLYESAMAIRR
                                                                                      

Mb1561|M.bovis_AF2122/97            VGQLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGG-----R
Rv1534|M.tuberculosis_H37Rv         VGQLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGG-----R
Mflv_2452|M.gilvum_PYR-GCK          AQTMVSEGS---RHWAAGAFGDRSFAEVVTGDICTLVNGY---------R
Mvan_4199|M.vanbaalenii_PYR-1       AQTMVSEGA---RHWAAGAFGSRSFAEVVTADICTLVNGYTARRPHVEFR
TH_0258|M.thermoresistible__bu      AQMLVSEGV---RHWAAGGFGDRSFTEVVAGDIAALIDGYN-------LR
MSMEG_4825|M.smegmatis_MC2_155      AMMMVSEGA---RHWAAGAFGARSFADVVASDIATLIAGSTG-------R
MMAR_1492|M.marinum_M               FENFTSVLV---GTSGSSGPGGLGVTITDEDAITTLSRIWKK-------T
MUL_2448|M.ulcerans_Agy99           FENFTSVLV---GTSGSSGPGGLGVTITDEDAITTLSRIWKK-------T
MAV_1952|M.avium_104                IGMLLVERA--LNQWLSTT--DRGLDDIIRQEFAALPGVVK---------
MAB_4027|M.abscessus_ATCC_1997      ITGLSMAAT---LKAIRGELEGDAREAYIGSFIQLVRTATTGST-----P
MLBr_02677|M.leprae_Br4923          HHRLPEASPARNQTGAAPTHREHVARPSCEALTRHIRHRSTRTRSHRGKR
                                       :                                              

Mb1561|M.bovis_AF2122/97            AART---------
Rv1534|M.tuberculosis_H37Rv         AART---------
Mflv_2452|M.gilvum_PYR-GCK          HTP----------
Mvan_4199|M.vanbaalenii_PYR-1       DRP----------
TH_0258|M.thermoresistible__bu      LRR----------
MSMEG_4825|M.smegmatis_MC2_155      RRP----------
MMAR_1492|M.marinum_M               LYGF---------
MUL_2448|M.ulcerans_Agy99           LYGF---------
MAV_1952|M.avium_104                -------------
MAB_4027|M.abscessus_ATCC_1997      VANS---------
MLBr_02677|M.leprae_Br4923          GELLPRAATSSLL