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MIVVGNFTQSNYVPASRGRRSSQLSGDDREQAILAVAERLLAERPLGDFSVDELAKGAGISRPTFYFYFP SKNAVLLSLLDDLNMKSRSAVEALAEQLPADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRL WSTVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFSDEKPLIPDKKVIDTLVHIW LASIYGS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_01070 | - | - | 100% (217) | putative TetR-family transcriptional regulator |
| M. leprae Br4923 | MLBr_00064 | - | 2e-60 | 57.50% (200) | putative transcriptional regulator |
| M. leprae Br4923 | MLBr_00717 | - | 3e-08 | 36.67% (60) | putative TetR-family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3885 | ethR | 1e-63 | 60.40% (202) | transcriptional regulatory repressor protein (TETR-family) |
| M. gilvum PYR-GCK | Mflv_0963 | - | 3e-61 | 54.03% (211) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3855 | ethR | 1e-63 | 60.40% (202) | transcriptional regulatory repressor protein (TETR-family) |
| M. abscessus ATCC 19977 | MAB_0984c | - | 5e-56 | 49.26% (203) | TetR family transcriptional regulator |
| M. marinum M | MMAR_5405 | ethR | 3e-62 | 55.61% (214) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0173 | - | 6e-59 | 53.59% (209) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6441 | - | 4e-58 | 54.29% (210) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1150 | - | 4e-67 | 60.98% (205) | TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR |
| M. ulcerans Agy99 | MUL_5027 | ethR | 8e-62 | 55.94% (202) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_5684 | - | 1e-59 | 53.05% (213) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0173|M.avium_104 -MTTAGQTRAL-----------RGRRAIRPTGDEREQAILATALRLLETR
MSMEG_6441|M.smegmatis_MC2_155 -MTTASQTRTP-----------RGRRSARPSGDDREAAILATAQRLLETK
Mb3885|M.bovis_AF2122/97 -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
Rv3855|M.tuberculosis_H37Rv -MTTSAASQAS---------LPRGRRTARPSGDDRELAILATAENLLEDR
MMAR_5405|M.marinum_M MVSTSTASQAS---------PSRGRRSARPSGDERELAILNTAEKLLEDR
MUL_5027|M.ulcerans_Agy99 -MSTSTASQAS---------LSRGRRSARPSGDERELAILNTAEKLLEDR
Mvan_5684|M.vanbaalenii_PYR-1 -MRSSTRCKVSPVTATSPTRPARGRRAARPSGDDRELAILETAERLLADR
Mflv_0963|M.gilvum_PYR-GCK -MSSTTRTG-------------RGRRAARPSGDDRESAILTTAEQLLEQR
TH_1150|M.thermoresistible__bu -MSTASPVRS------------RGRRSTRPSGDDRELAILTTAEKLLAER
MLBr_01070|M.leprae_Br4923 MIVVGNFTQSN------YVPASRGRRSSQLSGDDREQAILAVAERLLAER
MAB_0984c|M.abscessus_ATCC_199 -MTKP---------------ATRGRKTTRPSGDERIQAILATAEELLGKR
: ***:: : :**:* *** .* .** :
MAV_0173|M.avium_104 PFAGISVDDLAKGAGLSRPTFYFYFKSKEAVVLSLLEPVIARADAEFDGA
MSMEG_6441|M.smegmatis_MC2_155 KFAEISVDDLAKGAGISRPTFYFYFPSKEAVLLSLIDPLIKRADSGFDNA
Mb3885|M.bovis_AF2122/97 PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
Rv3855|M.tuberculosis_H37Rv PLADISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNQADMALQTL
MMAR_5405|M.marinum_M PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
MUL_5027|M.ulcerans_Agy99 PMVDISVDDLAKGAGISRPTFYFYFPSKEAVLLTLLDRVVNEADAALDNL
Mvan_5684|M.vanbaalenii_PYR-1 SLAEISVDDLAKGAGISRPTFYFYFASKDAVLLTLLERVIAEADAALAQL
Mflv_0963|M.gilvum_PYR-GCK PLNDISVDDLARGAGISRPTFYFYFSSKDAVLLALLDRVIAEANARADAA
TH_1150|M.thermoresistible__bu PLAEISVDDLAKGAGLSRPTFYFYFPSKDAVLLALVERVIAEADQRADAA
MLBr_01070|M.leprae_Br4923 PLGDFSVDELAKGAGISRPTFYFYFPSKNAVLLSLLDDLNMKSRSAVEAL
MAB_0984c|M.abscessus_ATCC_199 PLADVSVDDLARGAGISRPTFYFYFSSKESVLLTLAERIIEEADANVASI
: .***:**:***:********* **::*:*:* : : .:
MAV_0173|M.avium_104 VQRLP---TDPRRVWRNGIKAFFTAFSSHRALARAATEALATSSELRSVW
MSMEG_6441|M.smegmatis_MC2_155 VESMP---ADPQRAIRRGIEIFFNSFGSHPATARAGTEALKSSPEFKEFW
Mb3885|M.bovis_AF2122/97 AENPA--DTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELW
Rv3855|M.tuberculosis_H37Rv AENPA--DTDRENMWRTGINVFFETFGSHKAVTRAGQAARATSVEVAELW
MMAR_5405|M.marinum_M AQAP---DVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISAEVRELW
MUL_5027|M.ulcerans_Agy99 AQAP---DVDHVTMWRNGINVFFETFGSHRAVVQGGQGVRSISTEVRELW
Mvan_5684|M.vanbaalenii_PYR-1 IAER---SSDRRTIWRRGINVFFETFGAHRAVCATTVGVKSTNSEARELW
Mflv_0963|M.gilvum_PYR-GCK LGGRDDRPLEPAGVWQ-AIKALFETFAAHRAVMLAGAAMRPNNPEVQRVW
TH_1150|M.thermoresistible__bu LNGMDARAVDPAGVWR-AINALFETFGAHRAVTLAGAAARTTNTEVDALW
MLBr_01070|M.leprae_Br4923 AEQLP---ADPAAVWRSAITAFFEVCGTHRAVAVAGAAAKATSPEVRRLW
MAB_0984c|M.abscessus_ATCC_199 DPAAM---TSPAQYWRAVIKAYFDAFGSHRALTVALSSMQGTSPELDQRW
. : * * .:* * . * *
MAV_0173|M.avium_104 SGFMQKWIDQTAAMITAERERGAAPDTIPAADLATSLNQMNERTMMAALS
MSMEG_6441|M.smegmatis_MC2_155 SGLMQKWIAATAALITAERERGAAPDTIPALDLATSLNLMNERTMMAALA
Mb3885|M.bovis_AF2122/97 STFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFA
Rv3855|M.tuberculosis_H37Rv STFMQKWIAYTAAVIDAERDRGAAPRTLPAHELATALNLMNERTLFASFA
MMAR_5405|M.marinum_M STFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFL
MUL_5027|M.ulcerans_Agy99 STFMQKWIAYTAKIIEAERERGAAPVTLPALELATALNLMNERTLSASFL
Mvan_5684|M.vanbaalenii_PYR-1 SRSMQRWIDHIAAVIEAERADGAAPVTVPARELSTALNLMNESVMTATFT
Mflv_0963|M.gilvum_PYR-GCK SHFMQKWIDYTAASIRAERERGAAPDTLPAEDLAIALNLMNERIMLSAFA
TH_1150|M.thermoresistible__bu SRFMKKWIDYTAESIRAERERGAAPDTIPAEDLAVSLNLMNERTMFAAFA
MLBr_01070|M.leprae_Br4923 STVMQQWIDYNTAAIQAERKCGVAPDTIPAEDLAVALQLMTERVMAATFS
MAB_0984c|M.abscessus_ATCC_199 SEVTENWVANTTVGIEAERARGAAPSVVPARDIAIALNLINQAMMRATFT
* :.*: : * *** *.** .:** ::: :*: :.: : :::
MAV_0173|M.avium_104 AETPAVAEDRVVDTLTHIWVSSIYGESG----
MSMEG_6441|M.smegmatis_MC2_155 DEQPGVAPEKVVATLTHIWLNSIYGTLPVGTA
Mb3885|M.bovis_AF2122/97 GEQPSVPEARVLDTLVHIWVTSIYGENR----
Rv3855|M.tuberculosis_H37Rv GEQPSVPEARVLDTLVHIWVTSIYGENR----
MMAR_5405|M.marinum_M AEEPSVPETHVVDTLVHIWVSSIYGEAR----
MUL_5027|M.ulcerans_Agy99 AEEPSVPETHVVDTLVHVWVSSIYGAAR----
Mvan_5684|M.vanbaalenii_PYR-1 GHQPAIPDDRVLDNLVHIWTTSIYGKTD----
Mflv_0963|M.gilvum_PYR-GCK SEQAAVTADRLVGTLAHIWVSSIYGTPRA---
TH_1150|M.thermoresistible__bu DEKPAVPEDRIVDTLAHIWLTSIYGTGR----
MLBr_01070|M.leprae_Br4923 DEKPLIPDKKVIDTLVHIWLASIYGS------
MAB_0984c|M.abscessus_ATCC_199 GQQPAVDDGKVVDTLLHVWLNAIYGGVCANS-
. . : ::: .* *:* :***