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VGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAIAAAAGVARGTFYFHFPTKEH VLVELERAEELAIVAKLRDPTADPTDLVSVLSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGE HPLAEFVIETIARAQRANRVPPDADAGELGVIFLTGLFALLATGATTPDARTALLNRFVTTVVHGMEAR
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_0249 | - | - | 100% (209) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0345 | - | 5e-07 | 28.40% (169) | transcriptional regulatory protein |
| M. marinum M | MMAR_3853 | - | 1e-06 | 31.82% (88) | putative regulatory protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0068c | - | 4e-08 | 30.12% (166) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1774 | - | 2e-44 | 44.90% (196) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0067c | - | 4e-08 | 30.12% (166) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00316 | - | 4e-05 | 29.08% (196) | putative TetR/AcrR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4352c | - | 1e-07 | 24.62% (195) | TetR family transcriptional regulator |
| M. avium 104 | MAV_4190 | - | 1e-57 | 63.54% (181) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6527 | - | 2e-39 | 44.02% (184) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1791 | - | 2e-44 | 47.40% (192) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 1e-109 | 96.17% (209) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4973 | - | 3e-43 | 43.88% (196) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_0249|M.marinum_M -MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAA
MUL_4864|M.ulcerans_Agy99 -MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAA
MAV_4190|M.avium_104 -----------------------------MFDAALAEISQRGLAAADVSA
MSMEG_6527|M.smegmatis_MC2_155 ----------MLRQERTGRWRKGMQTRERLLGAALAEFKRNGIAAADTAA
TH_1791|M.thermoresistible__bu ----------VLNERTSDRGSKGRQTRERLLGAAIAEFKRGGMAAADVAS
Mflv_1774|M.gilvum_PYR-GCK ---------MTPQIKQSARELRRLQTRERILGAAIAEFQASGMAGADVGA
Mvan_4973|M.vanbaalenii_PYR-1 --------MMAPQVRQTARELRRLQTRERILGAAIAEFQASGMAGADIGA
Mb0068c|M.bovis_AF2122/97 -----------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-VPVDE
Rv0067c|M.tuberculosis_H37Rv -----------MAPTDRRVRADAARNRARVLEVAYQTFAADGLS-VPVDE
MLBr_00316|M.leprae_Br4923 MSVPRSGLSVQMAQPARPLRADAARNRARILGVAYEAFATEGLS-VPIDE
MAB_4352c|M.abscessus_ATCC_199 --------------MVPLRQAQALATRQRLVDVATELFALHGFTSVTTTS
:. .* : *:: .
MMAR_0249|M.marinum_M IAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADPTDLVS
MUL_4864|M.ulcerans_Agy99 IAAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTADSTDLVS
MAV_4190|M.avium_104 IVADAGVARGTFYFHFPTKEHVLVEVERAEETRIVSELGGATG---DLAA
MSMEG_6527|M.smegmatis_MC2_155 IVAAAGVAHGTFFFHFPTKEHVLIELEAREQERMVTELTRLYTRPHSVRD
TH_1791|M.thermoresistible__bu IVAAAGVAHGTFFFHFPTKEHVLVELERREEERMAAELNRYFRTPHTVRQ
Mflv_1774|M.gilvum_PYR-GCK IVSAAGVAHGTFFFHFPSKEHVLLELERREEARMATEFVRYLRRSHDLTA
Mvan_4973|M.vanbaalenii_PYR-1 IVSAAGVAHGTFFFHFPSKEHVLLELERREESRMATEFARYLDKKHDLAS
Mb0068c|M.bovis_AF2122/97 IARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDA
Rv0067c|M.tuberculosis_H37Rv IARRAGVGAGTVYRHFPTKEALFQAVIADRMHRIIDKGHALLKSKHPGDA
MLBr_00316|M.leprae_Br4923 IARRAGVGAGTVYRHFPTKEALCAAVIGDRMPHLVDDGYVLLKSAGPGEA
MAB_4352c|M.abscessus_ATCC_199 LSEASGMTRGALYHHFANMTEVMEAVFERAEGFLVAEVNHSLTSIESPAE
: :*: *:.: **.. : : : .
MMAR_0249|M.marinum_M VLSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIE
MUL_4864|M.ulcerans_Agy99 VLSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHPLAEFVIE
MAV_4190|M.avium_104 VLNQLVQHVLSAEKRLGPAVFRDMLGLHFCSTRPVEDELAQHPLGQFLVG
MSMEG_6527|M.smegmatis_MC2_155 TLAETVRLLEKLERRLGRRLFKDFLALHFSTTRPPSQEWTRYPALTVIIS
TH_1791|M.thermoresistible__bu TLAEIVRLLEDLERRLGTRLFKDFLALHFSTTRPPSEEWSRHPVIAAVVE
Mflv_1774|M.gilvum_PYR-GCK ALTKVVGLIAGLEQRLGPVLFRELLALHFSPTRPSDDDWSDHPVIVSLVR
Mvan_4973|M.vanbaalenii_PYR-1 ALAKVVELISALERRFGPLLFKELLALHFSPTRPSTDEWSDHPVIVSLVG
Mb0068c|M.bovis_AF2122/97 LFAFLRSMVLQWG-ATDRGLVEALAGVG-IEISSAAP-EAEADFLDLLTD
Rv0067c|M.tuberculosis_H37Rv LFAFLRSMVLQWG-ATDRGLVEALAGVG-IEISSAAP-EAEADFLDLLTD
MLBr_00316|M.leprae_Br4923 LFTYLRSLVLHWG-ATDRGLVDALAGAGGIDILGVAP-DAEDAFLTILSD
MAB_4352c|M.abscessus_ATCC_199 RFLAIGSAVLDVLAREPIVQRIVFVEAPMALGWSRWRALDGGRSLGLIQD
: : : :
MMAR_0249|M.marinum_M TIARAQRANRVPPDADAGELGVIFLTGLFALLATGATTPDARTALLNRFV
MUL_4864|M.ulcerans_Agy99 TIAQAQRADRVAPDADAGELGVIFLTGLFALLATGATTPDARTALLNGFV
MAV_4190|M.avium_104 VIGRAQDAGQVASDVDAAELATFFLTGLFALLATGAHDG----ALLSHYV
MSMEG_6527|M.smegmatis_MC2_155 ELQRAQQRGEIPADVDVMHVGVSFVVGLYALLITIPEARDARAPVLEVYL
TH_1791|M.thermoresistible__bu ELQRARDRGEIPEDVDVMHNGVSFLTGLYALLITMPESHDLRAPALSEYL
Mflv_1774|M.gilvum_PYR-GCK EIERARGDGEVHPEVDAFFSAAFFLLGVYGVLTTVTSS-DTRDAMLANLI
Mvan_4973|M.vanbaalenii_PYR-1 AIERARGDGEIHPEVDAFYSAAFFLLGIYGVLTTVARG-DIRDAMLANLI
Mb0068c|M.bovis_AF2122/97 LLRAAQRAGTVRPDVDVLEVKTLLVG--------CQAMQSYNAELAAKVT
Rv0067c|M.tuberculosis_H37Rv LLRAAQRAGTVRPDVDVLEVKTLLVG--------CQAMQSYNAELAAKVT
MLBr_00316|M.leprae_Br4923 LLYAAQYAGTARTDVGVREVKSILVG--------CQAMEAYNSALAERVT
MAB_4352c|M.abscessus_ATCC_199 ILEELYRRGELVEAVDPQMAAQLILGAINESGMYAAAAPSERSSRAAEQL
: . .. ::
MMAR_0249|M.marinum_M TTVVHGMEAR--------
MUL_4864|M.ulcerans_Agy99 TTVVHGMEAR--------
MAV_4190|M.avium_104 TTIVKGMEKR--------
MSMEG_6527|M.smegmatis_MC2_155 TTYLYGLRVLP-------
TH_1791|M.thermoresistible__bu TTYVHGMRVRSDPPAIAR
Mflv_1774|M.gilvum_PYR-GCK TTARRGLESR--------
Mvan_4973|M.vanbaalenii_PYR-1 TTARRGLETR--------
Mb0068c|M.bovis_AF2122/97 DVALDGLRANRK------
Rv0067c|M.tuberculosis_H37Rv DVALDGLRANRK------
MLBr_00316|M.leprae_Br4923 DVVVDGLRAAR-------
MAB_4352c|M.abscessus_ATCC_199 TLLCRGLLSPRSG-----
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