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AGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADADVGTIVAAAGVAHGTFFFHFPTKEHVLLELEQRE EERIAKQFAQFVKKPHDLEAALREIVRLVIGLERRLGDLLFKDFLALHFSQTRPRVDEGMEHPVIARVTE EIEAARQRGDVAADVNPVNSAVFFLLGFYALLVTTNDWPTRDEVLDDYVRRTLRSMRP*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_6604 | - | - | 100% (199) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6527 | - | 5e-51 | 53.12% (192) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_3807 | - | 6e-10 | 33.33% (156) | TetR-type regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 3e-07 | 26.13% (199) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4907 | - | 2e-76 | 71.79% (195) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 3e-07 | 26.13% (199) | transcriptional regulator |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1379c | - | 2e-06 | 26.52% (132) | TetR family transcriptional regulator |
| M. marinum M | MMAR_0249 | - | 3e-39 | 46.03% (189) | TetR family transcriptional regulator |
| M. avium 104 | MAV_2459 | - | 5e-84 | 76.53% (196) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_1661 | - | 3e-76 | 69.85% (199) | transcriptional regulator, TetR family protein |
| M. ulcerans Agy99 | MUL_4864 | - | 5e-39 | 46.03% (189) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1513 | - | 7e-77 | 70.77% (195) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_6604|M.smegmatis_MC2_155 --------MAGADGLTAREAKRLQTRERLMGAAIAEFKRAGMADADVGTI
MAV_2459|M.avium_104 ----------MADRLSAREAKRLQTRERLMGAAIAEFARAGMAEADVGAI
Mflv_4907|M.gilvum_PYR-GCK ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGMAEADVSTI
Mvan_1513|M.vanbaalenii_PYR-1 ----------MADGITAREAKRLQTRERLLGAAIAEFKRAGKDESDVGAI
TH_1661|M.thermoresistible__bu --------MARAEKPSAREAKRLQTRERLLGAAIAEFKRTGMAEADVRAI
MMAR_0249|M.marinum_M MGSTASTTAPHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
MUL_4864|M.ulcerans_Agy99 MGSTASTTAAHSPQQKVREAQRLRTRARVFDAAVAEIGRRGLAGADVAAI
Mb1561|M.bovis_AF2122/97 -----MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADI
Rv1534|M.tuberculosis_H37Rv -----MSRASARRRRAVSDEDKSQRRDEILAAAKIVFAHKGFHATTVADI
MAB_1379c|M.abscessus_ATCC_199 ----------MPEQLSRFERRKQETRREILGAALACFAERGYHATGIADI
: : . * .:: ** : . * : : *
MSMEG_6604|M.smegmatis_MC2_155 VAAAGVAHGTFFFHFPTKEHVLLELEQREEERIAKQFAQFVK-----KPH
MAV_2459|M.avium_104 VAAAGVAHGTFFFHFPTKEHVLLELERREEERIAKQFAQFLK-----SEH
Mflv_4907|M.gilvum_PYR-GCK VGAAGVAHGTFFFHFPTKEHVLLELERREEDRIAKRFATFTK-----THH
Mvan_1513|M.vanbaalenii_PYR-1 VAAAGVAHGTFFFHFPTKEHVLLELERREEDRMAKRFATFTK-----THH
TH_1661|M.thermoresistible__bu VAAAGVAHGTFFFHFPTKEHVLLELERREEERIARQFSRFLE-----TEH
MMAR_0249|M.marinum_M AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTA-----DPT
MUL_4864|M.ulcerans_Agy99 AAAAGVARGTFYFHFPTKEHVLVELERAEELAIVAKLRDPTA-----DST
Mb1561|M.bovis_AF2122/97 AKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTEA
Rv1534|M.tuberculosis_H37Rv AKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAHVAAELARVGGSTEA
MAB_1379c|M.abscessus_ATCC_199 VRRVGIAQGTFYLYFQSKREIVEQILDDLMERLSAALLDLPPSAP-TSLA
. .*:* * :: :* :* .:. : : .
MSMEG_6604|M.smegmatis_MC2_155 DLEAALREIVRLVIGLERRLGDLLFKDFLALHFSQTRPRVDEGMEHP-VI
MAV_2459|M.avium_104 DLASALNEAVRLVVGLERRLGDMLFNDFLALHFSQTRPQTEDGRDHP-LI
Mflv_4907|M.gilvum_PYR-GCK DLSAVLREAADLVLGLERRLGVVLFKDFLALHFSPTRPPAEHGGDHP-VV
Mvan_1513|M.vanbaalenii_PYR-1 DLASALREAAHLVMGLERRLGVVLFKDFLALHFSPTRPPAEHGDDHP-LV
TH_1661|M.thermoresistible__bu DLVGTLKEAVRLVLDIEDRLGPVLFKDFLALHFSPTRPPAEEGQDHP-LI
MMAR_0249|M.marinum_M DLVSVLSSLVHQVVAVERRLGPVVFRDMLGLHFAPTRPVEDQLGEHP-LA
MUL_4864|M.ulcerans_Agy99 DLVSVLSSLAHQVVAVERRLGPLVFRDMLGLHFAPTRPVEDQLGEHP-LA
Mb1561|M.bovis_AF2122/97 PLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLGGIYERFI
Rv1534|M.tuberculosis_H37Rv PLRALLQAAVQATFEFFETDKATVKLLFRDAYALGGRFEEHLGGIYERFI
MAB_1379c|M.abscessus_ATCC_199 EYRDQAEHISTSLTGVLSADPQAARFLLLQAAAVDDDMAERVLAFYDAAA
. : :
MSMEG_6604|M.smegmatis_MC2_155 ARVTEEIEAARQRGDVAADVNPVNS--AVFFLLGFYALLVTTNDWP-TRD
MAV_2459|M.avium_104 VLVANEIEGAQQRGETDPHVNPMNS--AVFFLLGLYALLITTNHWP-TGH
Mflv_4907|M.gilvum_PYR-GCK VLVAAQIEHARQRGETAADVTPMNS--AIYFLLGLYALLVTTDEST-GRS
Mvan_1513|M.vanbaalenii_PYR-1 VLVADQIDNARQRGDTAADVTPMNS--AIYFLLGLYALLITTDDST-GRR
TH_1661|M.thermoresistible__bu VSVAEEIERAQRAGEVDAEVNPWNS--AVFFLLGLYALLTTTHAWP-NRA
MMAR_0249|M.marinum_M EFVIETIARAQRANRVPPDADAGEL--GVIFLTGLFALLATGATTPDART
MUL_4864|M.ulcerans_Agy99 EFVIETIAQAQRADRVAPDADAGEL--GVIFLTGLFALLATGATTPDART
Mb1561|M.bovis_AF2122/97 DDIEAVVVAAQRRGEVVEAPSRMAAY-TLAALVGQLAHRRLNTDDNVTAA
Rv1534|M.tuberculosis_H37Rv DDIEAVVVAAQRRGEVVEAPSRMAAY-TLAALVGQLAHRRLNTDDNVTAA
MAB_1379c|M.abscessus_ATCC_199 AIQATYLQHGISAGYFRSDLDAGHAARAVNGMLLASAFYSLRDPSPAAFE
: . . : : *
MSMEG_6604|M.smegmatis_MC2_155 EVLDDYVRRTLRSMRP---------------
MAV_2459|M.avium_104 ALLEDYVARTLRSLKP---------------
Mflv_4907|M.gilvum_PYR-GCK VLVTDYLTRTLRSLQ----------------
Mvan_1513|M.vanbaalenii_PYR-1 ELVDDYLTRTLRSLQ----------------
TH_1661|M.thermoresistible__bu GMVDDFVANTLRSLRPRLTRR----------
MMAR_0249|M.marinum_M ALLNRFVTTVVHGMEAR--------------
MUL_4864|M.ulcerans_Agy99 ALLNGFVTTVVHGMEAR--------------
Mb1561|M.bovis_AF2122/97 QVADFVVSLVLDGLRPRALAVGARGGRAART
Rv1534|M.tuberculosis_H37Rv QVADFVVSLVLDGLRPRALAVGARGGRAART
MAB_1379c|M.abscessus_ATCC_199 QLAHAVREILYYGLASDHHPQIAD-------
: .: