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VASTSSGRRGPGRPPNPARARERQRALTEAAALEFAEKGYHKASITDITQRAGVGRGTFYLYFDTKRDVL DAVIDSYFQRTVAAVNDTSDLLGNASDFELHLRTVFTRLFDMLDNSPEIMQVILREGLLDTAMTKRMFGI LDLIEAINVTIIEQAVMDGAITAAVDIPFLAHAITGLSMAATLKAIRGELEGDAREAYIGSFIQLVRTAT TGSTPVANS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4027 | - | - | 100% (219) | TetR/AcrR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1525c | - | 2e-21 | 30.64% (173) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1379c | - | 4e-20 | 28.65% (171) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 1e-08 | 25.61% (164) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_4467 | - | 6e-10 | 33.98% (103) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 1e-08 | 25.61% (164) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02568 | - | 3e-07 | 29.47% (95) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_0150 | - | 3e-09 | 30.30% (198) | TetR family transcriptional regulator |
| M. avium 104 | MAV_0146 | - | 2e-10 | 29.47% (207) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_1565 | - | 1e-09 | 33.33% (120) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4015 | - | 4e-10 | 45.71% (70) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_4947 | - | 1e-08 | 29.80% (198) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_1893 | - | 2e-09 | 33.93% (112) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_4467|M.gilvum_PYR-GCK ------------------MPPGSSD---ALSAKGR--QTRDALAQAARKL
Mvan_1893|M.vanbaalenii_PYR-1 ------------------MPPGPAE---SLSAKGR--QTRDAIEQAARKL
Mb1561|M.bovis_AF2122/97 ------------------MSRASARRRRAVSDEDKS-QRRDEILAAAKIV
Rv1534|M.tuberculosis_H37Rv ------------------MSRASARRRRAVSDEDKS-QRRDEILAAAKIV
MMAR_0150|M.marinum_M ---------------------MVSEYSLTMSTSGR-----DRLLSAALKL
MUL_4947|M.ulcerans_Agy99 -----------------------------MSTSGR-----DRLLSAALKL
MAV_0146|M.avium_104 -----------------------------MLSSGR-----DRLLSAALRL
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
MAB_4027|M.abscessus_ATCC_1997 ----------------MASTSSGRRGPGRPPNPARARERQRALTEAAALE
MLBr_02568|M.leprae_Br4923 ------------------MAGGAKR----IPRAVRE----QQMLDAAVQM
MSMEG_1565|M.smegmatis_MC2_155 -----------------MRQTRAARSGPGRPAGTDSVDTRQRVIDAACRC
: **
Mflv_4467|M.gilvum_PYR-GCK FAERGFHGTTLSDITSAAGKSP--AAFYRYFSDKEDLLAALAES---FLH
Mvan_1893|M.vanbaalenii_PYR-1 FAERGFHGTTLGDITSAAGKSP--AVFYRYFADKEDLLAALAES---FLH
Mb1561|M.bovis_AF2122/97 FAHKGFHATTVADIAKQAGLAY--GLIYWYFDSKDDLFHALMAGEEEALR
Rv1534|M.tuberculosis_H37Rv FAHKGFHATTVADIAKQAGLAY--GLIYWYFDSKDDLFHALMAGEEEALR
MMAR_0150|M.marinum_M FAAKGYAATSVADIQRCSGLAPGSGALYKHFGSKHELLEAAVEHR----I
MUL_4947|M.ulcerans_Agy99 FAVKGYAATSVADIQRCSGLAPGSGALYKHFGSKHELLEAAVEHR----I
MAV_0146|M.avium_104 FAAKGYAATSVADIQRESGLAPGSGALYKHFGSKRELLEAAVAHR----I
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAH--GSFYRYFDSKEEIFIELLREL----V
MAB_4027|M.abscessus_ATCC_1997 FAEKGYHKASITDITQRAGVGR--GTFYLYFDTKRDVLDAVIDSY--FQR
MLBr_02568|M.leprae_Br4923 FSVNGYHKTSMDAIAAEAQISK--PMLYLYYGSKEDLFGACLNR-----E
MSMEG_1565|M.smegmatis_MC2_155 FAQFGYGPATNNQIAEMAGVTA--GSVYYHFGTKNKLFEAVCDD-----V
*: *: : * : .* :: * .::
Mflv_4467|M.gilvum_PYR-GCK EVVAPSGLSVPLPESPDDDAFFTAVVTGYWTMFKQNIG-IMIAVAQLAAT
Mvan_1893|M.vanbaalenii_PYR-1 DVVAPSGLSVPLPESPDDDAFFTMVVTGYWTMFKQNIG-IMIAVAQLAAT
Mb1561|M.bovis_AF2122/97 AHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYAL
Rv1534|M.tuberculosis_H37Rv AHVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYAL
MMAR_0150|M.marinum_M DSIVAAREQYDAGEPGGVEQAVRTAGHLIWTNLKQSEDLLKVMLREPGAL
MUL_4947|M.ulcerans_Agy99 DSIVAAREQYDAGEPGGVEQAVRTAGHLIWTNLKQSEDLLKVMLREPGAL
MAV_0146|M.avium_104 ESIVTAREQYDAGQPGSVEQAVRTAGQLIWNNLKQSEDLLKVMLREPDEL
TH_4015|M.thermoresistible__bu EELRQPVRTDAGTEPKNPYERILRANRTYLEAYRANRA-IMIVWEQVASL
MAB_4027|M.abscessus_ATCC_1997 TVAAVNDTSDLLGNASDFELHLRTVFTRLFDMLDNSPEIMQVILREG-LL
MLBr_02568|M.leprae_Br4923 MSRFIAMVRADIDFTQSPKDLLRNTIVSFLRYIDANRASWIVMYIQAMSL
MSMEG_1565|M.smegmatis_MC2_155 YGKILTRVMLAVSGSHSVVGLLRAVLTESMRINHESPE--LAGFVATAPI
. . .
Mflv_4467|M.gilvum_PYR-GCK QPRFTLVQNEFRRFGMDIVAASVRRAQEQGYGT-ELNPEHTAAAIALLFE
Mvan_1893|M.vanbaalenii_PYR-1 QSRFALVQNEFRRFGMDIVAASVRRAQEQGYGR-ELNAEHTAAAIALLFE
Mb1561|M.bovis_AF2122/97 GGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVV-EAPSRMAAYTLAALVG
Rv1534|M.tuberculosis_H37Rv GGRFEEHLGGIYERFIDDIEAVVVAAQRRGEVV-EAPSRMAAYTLAALVG
MMAR_0150|M.marinum_M GDLDEKTWQIITDNAYQRFADELAASNRSGRTR-IPDPEAAASVAIASLS
MUL_4947|M.ulcerans_Agy99 GDLDEKTWQIITDNAYQRFADELAASNRSGRTR-IPDPEAAASVAIASLS
MAV_0146|M.avium_104 GDLDEKTWQVITDNAYQRFADELAASNRAGRTS-IPDPEAAAAVAIGSLS
TH_4015|M.thermoresistible__bu NEHVEQLRREYSDRFAARIERAIIRWQEAGLADPAIDPRYAAAALSGMLS
MAB_4027|M.abscessus_ATCC_1997 DTAMTKRMFGILDLIEAINVTIIEQAVMDGAITAAVDIPFLAHAITG-LS
MLBr_02568|M.leprae_Br4923 PA-FAQTVREARDQITELVAGLMRVGTRSSRPD--HEYEIMAGALVGAGE
MSMEG_1565|M.smegmatis_MC2_155 DARRHRELAESFATQGARMADALTDAVRSGQDAGDIAADLDPVRVARLIS
: . .
Mflv_4467|M.gilvum_PYR-GCK NFTTVFVGASG--LGVQMTDQDAIATLSRIWKKTLYGY------------
Mvan_1893|M.vanbaalenii_PYR-1 NFTTVFVGASG--LDVDIDDEAAIATLSRIWKKTLYGY------------
Mb1561|M.bovis_AF2122/97 QLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART---
Rv1534|M.tuberculosis_H37Rv QLAHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART---
MMAR_0150|M.marinum_M YAATLQALTGRSPGNIDDSRYFEAWVNQTVSMLSQYTN-PAPSRKP----
MUL_4947|M.ulcerans_Agy99 YALTLQALTGRSPGNIDDSRYFEAWVNQTVSMLSQYTN-PAPSRKPQADN
MAV_0146|M.avium_104 YAATLQALTGRLPGNTDEDRYFEAWVNQTVSVLAQYTNRRKPLNDNDNDS
TH_4015|M.thermoresistible__bu NFAYRWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA-------
MAB_4027|M.abscessus_ATCC_1997 MAATLKAIRGELEGDAREAYIGSFIQLVRTATTGSTPVANS---------
MLBr_02568|M.leprae_Br4923 AMATR-LTTGDIAVDEAAELMINLFWHGLKGAPADRDFGPSIVAG-----
MSMEG_1565|M.smegmatis_MC2_155 AVVDGFAHAAVSADPDEMDNMNELFQSLLLDTT-----------------
Mflv_4467|M.gilvum_PYR-GCK ----
Mvan_1893|M.vanbaalenii_PYR-1 ----
Mb1561|M.bovis_AF2122/97 ----
Rv1534|M.tuberculosis_H37Rv ----
MMAR_0150|M.marinum_M ----
MUL_4947|M.ulcerans_Agy99 KFQE
MAV_0146|M.avium_104 GAQT
TH_4015|M.thermoresistible__bu ----
MAB_4027|M.abscessus_ATCC_1997 ----
MLBr_02568|M.leprae_Br4923 ----
MSMEG_1565|M.smegmatis_MC2_155 ----