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TPRPENLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVAARTSAELESFVADAKAAGGQALACSTDITDE ASVERLVDATVETFGRVDILVNNSGIVATTPLIEQSADEWDRVVATNLRGTFLATRAVGRHLVAQRSGKV INIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQVNAIAPGYFATSLNADMRADADMAAKVV RAIPARRMGEPEELTSWLLLLAGSASDFMTGEVIVIDGGQSVR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_4117 | - | - | 100% (254) | 2-deoxy-D-gluconate 3-dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_3009 | - | 2e-42 | 39.51% (243) | 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2536 | - | 3e-42 | 37.80% (246) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 3e-39 | 36.84% (247) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1263 | - | 7e-42 | 36.73% (245) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv1928c | - | 3e-39 | 36.84% (247) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-31 | 32.49% (237) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_2032 | - | 3e-39 | 37.05% (251) | 3-oxoacyl- |
| M. marinum M | MMAR_2849 | - | 2e-39 | 38.04% (255) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1832 | - | 2e-41 | 39.34% (244) | 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase |
| M. thermoresistible (build 8) | TH_2623 | - | 3e-44 | 39.52% (248) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0336 | - | 5e-37 | 35.41% (257) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_0894 | - | 2e-44 | 40.47% (257) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1963c|M.bovis_AF2122/97 --MSVLDL-----------FDLHGKRALITGASTGIGKRVALAYVEAGAQ
Rv1928c|M.tuberculosis_H37Rv --MSVLDL-----------FDLHGKRALITGASTGIGKRVALAYVEAGAQ
MMAR_2849|M.marinum_M --MSVLDL-----------FDLSGKRALITGASTGIGKKVALAYAEAGAQ
TH_2623|M.thermoresistible__bu --MGVLDK-----------FRLDDKVVIVTGASSGLGVAFARACAEAGAD
Mvan_0894|M.vanbaalenii_PYR-1 MTVDIAREQPATAPRPDQMFDLTGRTALVTGASSGLGVQFALALRSAGAE
MAV_1832|M.avium_104 -------------------MNFTSKVAVVTGAASGIGEATAKRLAEDGAK
MUL_0336|M.ulcerans_Agy99 -----------------MVDELAGKIAIVTGGASGIGRATVARFIAEGAR
MSMEG_4117|M.smegmatis_MC2_155 --------------MTPRPENLEGKVAIVTGAGRGLGRAMAKGLVDAGAA
Mflv_1263|M.gilvum_PYR-GCK ---------------MSDRFSMEGRVAVITGGGTGIGRASALVLAEHGAD
MAB_2032|M.abscessus_ATCC_1997 ---------------MSGKE-FEGQVALVTGASRGIGRSIALALAEHGAD
MLBr_01807|M.leprae_Br4923 ---MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHR
: .: ::**. *:* . *
Mb1963c|M.bovis_AF2122/97 VAIAARHLDA-LEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAEL
Rv1928c|M.tuberculosis_H37Rv VAIAARHLDA-LEKLADEIGTSGGKVVPVCCDVSQHQQVTSMLDQVTAEL
MMAR_2849|M.marinum_M VAVAARHSDA-LQVVADEIAGVGGKALPIRCDVTQPDQVRGMLDQMTGEL
TH_2623|M.thermoresistible__bu VVLAARRVER-LQQTAEQVRATGRRALTVATDVVDPQQCQEMVDAAMTEF
Mvan_0894|M.vanbaalenii_PYR-1 VVVAARRADR-LAELCEAHEGLS----AVSCDVADPASIESAYQCVEERV
MAV_1832|M.avium_104 VVVADINEDG-GERVVAEIAERGGEAAFLRTDISIEEDVNSLIDFAVSTY
MUL_0336|M.ulcerans_Agy99 VVIADVEEER-GESLAAALG---ADAMFCRTDVSQPEQVAAVVAAAVDNF
MSMEG_4117|M.smegmatis_MC2_155 VTVAARTSAE-LESFVADAKAAGGQALACSTDITDEASVERLVDATVETF
Mflv_1263|M.gilvum_PYR-GCK VVLAGRRAEP-LKETAAEVEALGRRALAVPTDVTDADACQALVDTTLAEF
MAB_2032|M.abscessus_ATCC_1997 IALHYGNSKPAAEEVAEKISALGRRVLLCQGDIADPAVPELLADTVHAEF
MLBr_01807|M.leprae_Br4923 VAVTHR------------ASVVPDWFFGVECDVTDNDAIGAAFKAVEEHQ
:.: *:
Mb1963c|M.bovis_AF2122/97 GGIDIAVCNAGII--TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAM
Rv1928c|M.tuberculosis_H37Rv GGIDIAVCNAGII--TVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAM
MMAR_2849|M.marinum_M GGIDIAVCNAGIV--SVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAM
TH_2623|M.thermoresistible__bu GRVDVLVNNAGVG--TAVPATRETPEEFRTVIDINLNGSYWAAQACGR--
Mvan_0894|M.vanbaalenii_PYR-1 GAVDILVNNAGTS--IPARAEDESLTDFQYVLDVNLVGAFRLTQLVGRKM
MAV_1832|M.avium_104 GGLHLAHNNAAVAHTPTP-LHELSTDVFDTVTGIGLRGTFFCMRAEIAHM
MUL_0336|M.ulcerans_Agy99 GGLHVMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHM
MSMEG_4117|M.smegmatis_MC2_155 GRVDILVNNSGIV-ATTP-LIEQSADEWDRVVATNLRGTFLATRAVGRHL
Mflv_1263|M.gilvum_PYR-GCK GRLDVLLNNAGGG--ETKSLMKWTDDEWHHVLDLNLSSAWYLSRAAAKPM
MAB_2032|M.abscessus_ATCC_1997 GRIDVLVNNAGTH--GAGLLLDIAPDYLEETVATNLLGPIRMTKAVVAHM
MLBr_01807|M.leprae_Br4923 GPVEVLVANAGIT--SDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNM
* :.: *:. .: . :
Mb1963c|M.bovis_AF2122/97 VKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELA-P
Rv1928c|M.tuberculosis_H37Rv VKQGQGGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELA-P
MMAR_2849|M.marinum_M VDQGLGGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELA-P
TH_2623|M.thermoresistible__bu VMRPGS-SIVNISSILGITTASLP-QAAYSASKAGVIGLTRDLAQQWTPR
Mvan_0894|M.vanbaalenii_PYR-1 IERGEG-SIVNVASILGMVAAAPNRQAAYCASKGGLINLTRELAVQWA-R
MAV_1832|M.avium_104 IGHGGG-AIVNTASGAALKA--AAGMHAYVATKHGIVGLTRNAGLDYA-R
MUL_0336|M.ulcerans_Agy99 AAHGGG-SIVNLTSIGGIQA--GGGVMTYRASKGAVIQFTKSAAIELA-H
MSMEG_4117|M.smegmatis_MC2_155 VAQRSG-KVINIASNFALQG--VANHAAYSASKAGVIAFTRSMAIEWA-R
Mflv_1263|M.gilvum_PYR-GCK IAQGSG-AIVNISSGAGLLA--MPQAPIYGAAKAGLQNLTGSMAAAWT-R
MAB_2032|M.abscessus_ATCC_1997 LGQRYG-RIINISSVAADKP--DSGQSTYAATKGGLESFTKAIAVEFA-S
MLBr_01807|M.leprae_Br4923 IKQRFG-RYIFMGSVVGLSG--VPGQANYAASKSGLIGMARSLARELG-S
: . : * . * ::* .: :: .
Mb1963c|M.bovis_AF2122/97 HKIRVNSVSPGYILTELVEPYTE----------YQP---LWEPKIPLGRL
Rv1928c|M.tuberculosis_H37Rv HKIRVNSVSPGYILTELVEPYTE----------YQP---LWEPKIPLGRL
MMAR_2849|M.marinum_M HQIRVNSVSPGYIRTELVEPLAD----------YHA---LWEPKIPLGRM
TH_2623|M.thermoresistible__bu KGIRVNAIAPGFFKSEMTDQYKP----------GYLDSQMPR--VLMGRT
Mvan_0894|M.vanbaalenii_PYR-1 YNVRVNALAPGFFPSELTTELLD----------DDAGGAYIRRNTPMARA
MAV_1832|M.avium_104 NGIRVNAVAPGSIKTPQMAS------------FPQEMQDEWERIIPMGRM
MUL_0336|M.ulcerans_Agy99 YEIRVNAIAPGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKRE
MSMEG_4117|M.smegmatis_MC2_155 DNIQVNAIAPGYFATSLNADMR----------ADADMAAKVVRAIPARRM
Mflv_1263|M.gilvum_PYR-GCK KGVRVNCIACGAVRTPGLEADAK---------RQGFDIDMIGQTNGSGRI
MAB_2032|M.abscessus_ATCC_1997 RNIISNAVAPGVVYTDMAEITRT---------HVPATFERLKAQILAKDF
MLBr_01807|M.leprae_Br4923 RSITANVVAPGFIDTEMTRAMDS------------KYQEAALQAIPLGRI
: * :: * . :
Mb1963c|M.bovis_AF2122/97 GRPEELAGLYLYLASEASSYMTGSDIVIDGG-------YTCP--
Rv1928c|M.tuberculosis_H37Rv GRPEELAGLYLYLASEASSYMTGSDIVIDGG-------YTCP--
MMAR_2849|M.marinum_M GRPEELTGLYLYLASAASSYMTGSDIVIDGG-------YTCP--
TH_2623|M.thermoresistible__bu GDPEELAATLVWLVSDAGGYVTGQTIVVDGG-------ITIT--
Mvan_0894|M.vanbaalenii_PYR-1 GRAGELSGALLLLASGAGSFITGQVIAVDGG-------WTAR--
MAV_1832|M.avium_104 GRPEEVADVVAFLLSDAASFITATTVEIDG-----AYLQSSK--
MUL_0336|M.ulcerans_Agy99 GTPEDIAEAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR--
MSMEG_4117|M.smegmatis_MC2_155 GEPEELTSWLLLLAGSASDFMTGEVIVIDGG-------QSVR--
Mflv_1263|M.gilvum_PYR-GCK AEPDEIGYGVLFFASDASSYCSGQTLYMHGG-------PGPAGV
MAB_2032|M.abscessus_ATCC_1997 AKPEIVADAVLYLASPHNTYITGEVLHIDGG-------YKMK--
MLBr_01807|M.leprae_Br4923 GAVEEIAGAVSFLASEDAGYISGAVIPVDGG-------LGMGH-
. : : . : :. : :.*