For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
LSGKEFEGQVALVTGASRGIGRSIALALAEHGADIALHYGNSKPAAEEVAEKISALGRRVLLCQGDIADP AVPELLADTVHAEFGRIDVLVNNAGTHGAGLLLDIAPDYLEETVATNLLGPIRMTKAVVAHMLGQRYGRI INISSVAADKPDSGQSTYAATKGGLESFTKAIAVEFASRNIISNAVAPGVVYTDMAEITRTHVPATFERL KAQILAKDFAKPEIVADAVLYLASPHNTYITGEVLHIDGGYKMK
Operon Prediction Model: Genebank
Paralogs
species | id | gene | e-value | identity (len) | annotation |
M. abscessus ATCC 19977 | MAB_2032 | - | - | 100% (254) | 3-oxoacyl- |
M. abscessus ATCC 19977 | MAB_1408c | - | 4e-34 | 34.32% (271) | putative short-chain dehydrogenase/reductase |
M. abscessus ATCC 19977 | MAB_4913c | - | 4e-33 | 35.37% (246) | putative short chain dehydrogenase/reductase |
Closest Orthologs (e-value cutoff: 1e-4)
species | id | gene | e-value | identity (len) | annotation |
M. bovis AF2122 / 97 | Mb0248c | fabG | 8e-32 | 35.37% (246) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. gilvum PYR-GCK | Mflv_1263 | - | 2e-33 | 34.84% (244) | short-chain dehydrogenase/reductase SDR |
M. tuberculosis H37Rv | Rv0242c | fabG | 9e-32 | 35.37% (246) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. leprae Br4923 | MLBr_02565 | fabG | 4e-27 | 31.98% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. marinum M | MMAR_0503 | fabG | 5e-31 | 34.15% (246) | 3-oxoacyl- |
M. avium 104 | MAV_5088 | fabG | 5e-32 | 38.31% (248) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. smegmatis MC2 155 | MSMEG_4117 | - | 4e-39 | 37.05% (251) | 2-deoxy-D-gluconate 3-dehydrogenase |
M. thermoresistible (build 8) | TH_2488 | - | 2e-32 | 36.69% (248) | PUTATIVE short-chain dehydrogenase/reductase SDR |
M. ulcerans Agy99 | MUL_1166 | fabG | 3e-31 | 34.15% (246) | 3-ketoacyl-(acyl-carrier-protein) reductase |
M. vanbaalenii PYR-1 | Mvan_0789 | - | 1e-33 | 38.13% (257) | acetoin reductases |
CLUSTAL 2.0.9 multiple sequence alignment MAB_2032|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0789|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1263|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4117|M.smegmatis_MC2_155 -------------------------------------------------- TH_2488|M.thermoresistible__bu -------------------------------------------------- Mb0248c|M.bovis_AF2122/97 MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPLTGSLLI Rv0242c|M.tuberculosis_H37Rv MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPLTGSLLI MMAR_0503|M.marinum_M MAPKLSSDLFSQVVNSGPGTFVAKQLGVPQAETLRRYRPGDPPLAGSLLI MUL_1166|M.ulcerans_Agy99 MAPRLSSDLFSQVVNSGPGTFVAKQLGVPQAETLRRYRPGDPPLAGSLLI MLBr_02565|M.leprae_Br4923 MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI MAV_5088|M.avium_104 -------------------------------------------------- MAB_2032|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0789|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1263|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4117|M.smegmatis_MC2_155 -------------------------------------------------- TH_2488|M.thermoresistible__bu -------------------------------------------------- Mb0248c|M.bovis_AF2122/97 GGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLK Rv0242c|M.tuberculosis_H37Rv GGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLK MMAR_0503|M.marinum_M GGEGRVAEPLRAALAKDYDQVSNNLGGRWADSFGGLVFDATGITDPAGLK MUL_1166|M.ulcerans_Agy99 GGEGRVAEPLRAALAKDYDQVSNNLGGRWADSFGGLVFDATGITDPAGLK MLBr_02565|M.leprae_Br4923 GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK MAV_5088|M.avium_104 -------------------------------------------------- MAB_2032|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0789|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1263|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4117|M.smegmatis_MC2_155 -------------------------------------------------- TH_2488|M.thermoresistible__bu -------------------------------------------------- Mb0248c|M.bovis_AF2122/97 GLHEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGK Rv0242c|M.tuberculosis_H37Rv GLHEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGK MMAR_0503|M.marinum_M GLHDFFKPVLRNLGASARVVVVGTTPDAIDNSHERIAQRALEGFTRSLAK MUL_1166|M.ulcerans_Agy99 GLHDFFKPVLRNLGASARVVVVGTTPDAIDNSHERIAQRALEGFTRSLAK MLBr_02565|M.leprae_Br4923 GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK MAV_5088|M.avium_104 -------------------------------------------------- MAB_2032|M.abscessus_ATCC_1997 -------------------------------------------------- Mvan_0789|M.vanbaalenii_PYR-1 -------------------------------------------------- Mflv_1263|M.gilvum_PYR-GCK -------------------------------------------------- MSMEG_4117|M.smegmatis_MC2_155 -------------------------------------------------- TH_2488|M.thermoresistible__bu -------------------------------------------------- Mb0248c|M.bovis_AF2122/97 ELRRGATTALVYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADD Rv0242c|M.tuberculosis_H37Rv ELRRGATTALVYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADD MMAR_0503|M.marinum_M ELRRGSTAALVYLSPEAKPAATGLESTVRFILSAKSAYVDGQVFYVGAAD MUL_1166|M.ulcerans_Agy99 ELRRASTAALVYLSPEAKPAATGLESTVRFILSAKSAYVDGQVFYVGAAD MLBr_02565|M.leprae_Br4923 ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD MAV_5088|M.avium_104 -----------------------------------------------MAE MAB_2032|M.abscessus_ATCC_1997 -----MSGKEFEGQVALVTGASRGIGRSIALALAEHGADIALHYGNSKPA Mvan_0789|M.vanbaalenii_PYR-1 -----MT---LNGKVALVTGAARGIGRGIALRLARDGADIALVDVLP-EG Mflv_1263|M.gilvum_PYR-GCK ---MSDR-FSMEGRVAVITGGGTGIGRASALVLAEHGADVVLA-GRRAEP MSMEG_4117|M.smegmatis_MC2_155 ---MTPRPENLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVA-ARTSAE TH_2488|M.thermoresistible__bu --------MEFQGLHVLVTGGTGGIGLACARAFAEAGAEVTVT-GRDAG- Mb0248c|M.bovis_AF2122/97 STPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHVVAIDVE-SAA Rv0242c|M.tuberculosis_H37Rv STPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHVVAIDVE-SAA MMAR_0503|M.marinum_M STPPADWDRPLEGKVAIVTGAARGIGQTIAEVFARDGASVVAIDVE-SAA MUL_1166|M.ulcerans_Agy99 STPPADWDRPLEGKVAIVTGAARGIGQTIAEVFARDGASVVAIDVE-SAA MLBr_02565|M.leprae_Br4923 STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVE-SAA MAV_5088|M.avium_104 S--------LLLGKVAVVTGAGQGIGREIARALHRHGARVVLADLDGSAA : . .::**. *:* * . ** :. MAB_2032|M.abscessus_ATCC_1997 AEEVAEKISALGRRVLLCQGDIADPAVPELLADTVHAEFGRIDVLVNNAG Mvan_0789|M.vanbaalenii_PYR-1 LDGVADKIAGIGGKTTMFVADVSDREQVFAAVDHAAAALGGFDIMVNNAG Mflv_1263|M.gilvum_PYR-GCK LKETAAEVEALGRRALAVPTDVTDADACQALVDTTLAEFGRLDVLLNNAG MSMEG_4117|M.smegmatis_MC2_155 LESFVADAKAAGGQALACSTDITDEASVERLVDATVETFGRVDILVNNSG TH_2488|M.thermoresistible__bu ---RGAAAAGAHPRLRFIRGDLADLASVQNLIR----YADAVDVLVNNAA Mb0248c|M.bovis_AF2122/97 ENLAETASKVGG--TALWLDVTADDAVDKISEHLRDHHGGKADILVNNAG Rv0242c|M.tuberculosis_H37Rv ENLAETASKVGG--TALWLDVTADDAVDKISEHLRDHHGGKADILVNNAG MMAR_0503|M.marinum_M DALAETAASVGG--TPLWLDVTADDAVDKITEHLRDHHGGKADILVNNAG MUL_1166|M.ulcerans_Agy99 DALAETAASVGG--TPLWLDVTADDAVDKITEHLRDHHGGKADILVNNAG MLBr_02565|M.leprae_Br4923 EALDETANRVGG--TTLSLDVTADDAVDKITEHLHDYQGGHADILVNNAG MAV_5088|M.avium_104 RSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGG-LDVFVNNAG :: . *:::**:. MAB_2032|M.abscessus_ATCC_1997 THGAGLLLDIAPDYLEETVATNLLGPIRMTKAVVAHMLGQ------RYGR Mvan_0789|M.vanbaalenii_PYR-1 IALVGPISDVTPEQIEKLWAINVNGVLWGTQAAVAKFKELKNKDKGRVSR Mflv_1263|M.gilvum_PYR-GCK GGETKSLMKWTDDEWHHVLDLNLSSAWYLSRAAAKPMIAQ------GSGA MSMEG_4117|M.smegmatis_MC2_155 IVATTPLIEQSADEWDRVVATNLRGTFLATRAVGRHLVAQ------RSGK TH_2488|M.thermoresistible__bu SFPGALTVEQDAESFTRTFATNVTGTYFLTAGLIPGMLAR------GRGS Mb0248c|M.bovis_AF2122/97 ITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIG------EGGR Rv0242c|M.tuberculosis_H37Rv ITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIG------EGGR MMAR_0503|M.marinum_M ITRDKLLANMDDARWDSVIAVNLLAPLRLTEGLVGNGSIG------AGGR MUL_1166|M.ulcerans_Agy99 ITRDKLLANMDDARWDSVIAVNLLAPLRLTEGLVGNGSIG------AGGR MLBr_02565|M.leprae_Br4923 ITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSIS------KGGR MAV_5088|M.avium_104 ITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRER------KTGS :: . . MAB_2032|M.abscessus_ATCC_1997 IINISSVAADKPDSGQSTYAATKGGLESFTKAIAVEFASRNIISNAVAPG Mvan_0789|M.vanbaalenii_PYR-1 IINASSIAGHDGFAMLGPYSATKFAVRALTQAAAKEHAADGITVNAYCPG Mflv_1263|M.gilvum_PYR-GCK IVNISSGAGLLAMPQAPIYGAAKAGLQNLTGSMAAAWTRKGVRVNCIACG MSMEG_4117|M.smegmatis_MC2_155 VINIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQVNAIAPG TH_2488|M.thermoresistible__bu IVNITSMVATKAVPGASVYSSSKAAVESLTRSWAVEFAAHGIRVNAVAPG Mb0248c|M.bovis_AF2122/97 VIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPG Rv0242c|M.tuberculosis_H37Rv VIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPG MMAR_0503|M.marinum_M VIGLSSIAGIAGNRGQTNYGATKAGMIGIAQALAPSLAEKDITINAVAPG MUL_1166|M.ulcerans_Agy99 VIGLSSIAGIAGNRGQTNYGATKAGMIGIAQALAPSLAEKDITINAVAPG MLBr_02565|M.leprae_Br4923 VIVLSSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPG MAV_5088|M.avium_104 IVNMSSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQPG :: :* . *.::* .: :: : * : .: *. * MAB_2032|M.abscessus_ATCC_1997 VVYTDM--------AEITRTHVPATFERLKAQILAKDFAKPEIVADAVLY Mvan_0789|M.vanbaalenii_PYR-1 VVGTDMWVEIDKRFAELTGAAEGETYDKFVGGIALGRAETPDDVAGFVSY Mflv_1263|M.gilvum_PYR-GCK AVRTPG--------LEADAKRQGFDIDMIGQTNGSGRIAEPDEIGYGVLF MSMEG_4117|M.smegmatis_MC2_155 YFATS---------LNADMRADADMAAKVVRAIPARRMGEPEELTSWLLL TH_2488|M.thermoresistible__bu PTSTDG--------VATEWG---ETNEALGRALPIGRTADPDEIAQAVVF Mb0248c|M.bovis_AF2122/97 FIETQM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY Rv0242c|M.tuberculosis_H37Rv FIETQM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY MMAR_0503|M.marinum_M FIETKM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY MUL_1166|M.ulcerans_Agy99 FIETKM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY MLBr_02565|M.leprae_Br4923 FIETQM-----------TAAIPLATREVGRRLNSLLQGGLPVDVAETIAY MAV_5088|M.avium_104 LIRTPM-----------TAAMPPDVFAEREAAVPMKRAGEPEEVAGAVVF * * : : MAB_2032|M.abscessus_ATCC_1997 LASPHNTYITGEVLHIDGGYKMK-- Mvan_0789|M.vanbaalenii_PYR-1 LAGPDADYMTGQSGLIDGGLVYR-- Mflv_1263|M.gilvum_PYR-GCK FASDASSYCSGQTLYMHGGPGPAGV MSMEG_4117|M.smegmatis_MC2_155 LAGSASDFMTGEVIVIDGGQSVR-- TH_2488|M.thermoresistible__bu LASSRASFITGAVLHVDGGGIAV-- Mb0248c|M.bovis_AF2122/97 FASPASNAVTGNVIRVCGQAMIGA- Rv0242c|M.tuberculosis_H37Rv FASPASNAVTGNVIRVCGQAMIGA- MMAR_0503|M.marinum_M FASPASNAVTGNVIRVCGQAMIGA- MUL_1166|M.ulcerans_Agy99 FASPASNAVTGNVIRVCGQAMIGA- MLBr_02565|M.leprae_Br4923 FAIPASNAVTGNVIRVCGQAMLGA- MAV_5088|M.avium_104 LASELSSYITGTVLGVGGGRYM--- :* :* : *