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M. abscessus ATCC 19977 MAB_2032 (-)

annotation: 3-oxoacyl-
coordinates: 2031977 - 2032741
length: 254

LSGKEFEGQVALVTGASRGIGRSIALALAEHGADIALHYGNSKPAAEEVAEKISALGRRVLLCQGDIADP
AVPELLADTVHAEFGRIDVLVNNAGTHGAGLLLDIAPDYLEETVATNLLGPIRMTKAVVAHMLGQRYGRI
INISSVAADKPDSGQSTYAATKGGLESFTKAIAVEFASRNIISNAVAPGVVYTDMAEITRTHVPATFERL
KAQILAKDFAKPEIVADAVLYLASPHNTYITGEVLHIDGGYKMK
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. abscessus ATCC 19977MAB_2032--100% (254)3-oxoacyl-
M. abscessus ATCC 19977MAB_1408c-4e-3434.32% (271) putative short-chain dehydrogenase/reductase
M. abscessus ATCC 19977MAB_4913c-4e-3335.37% (246) putative short chain dehydrogenase/reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb0248cfabG8e-3235.37% (246) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_1263-2e-3334.84% (244) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv0242cfabG9e-3235.37% (246) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_02565fabG4e-2731.98% (247) 3-ketoacyl-(acyl-carrier-protein) reductase
M. marinum MMMAR_0503fabG5e-3134.15% (246) 3-oxoacyl-
M. avium 104MAV_5088fabG5e-3238.31% (248) 3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155MSMEG_4117-4e-3937.05% (251) 2-deoxy-D-gluconate 3-dehydrogenase
M. thermoresistible (build 8)TH_2488-2e-3236.69% (248) PUTATIVE short-chain dehydrogenase/reductase SDR
M. ulcerans Agy99MUL_1166fabG3e-3134.15% (246) 3-ketoacyl-(acyl-carrier-protein) reductase
M. vanbaalenii PYR-1Mvan_0789-1e-3338.13% (257) acetoin reductases

CLUSTAL 2.0.9 multiple sequence alignment


MAB_2032|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0789|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1263|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4117|M.smegmatis_MC2_155      --------------------------------------------------
TH_2488|M.thermoresistible__bu      --------------------------------------------------
Mb0248c|M.bovis_AF2122/97           MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPLTGSLLI
Rv0242c|M.tuberculosis_H37Rv        MAPKRSSDLFSQVVNSGPGSFLARQLGVPQPETLRRYRAGEPPLTGSLLI
MMAR_0503|M.marinum_M               MAPKLSSDLFSQVVNSGPGTFVAKQLGVPQAETLRRYRPGDPPLAGSLLI
MUL_1166|M.ulcerans_Agy99           MAPRLSSDLFSQVVNSGPGTFVAKQLGVPQAETLRRYRPGDPPLAGSLLI
MLBr_02565|M.leprae_Br4923          MAPKCSSDLFSQIVSSGPGSFVAKQLGVPRPETLRRYRPSDAPLCGSLLI
MAV_5088|M.avium_104                --------------------------------------------------
                                                                                      

MAB_2032|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0789|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1263|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4117|M.smegmatis_MC2_155      --------------------------------------------------
TH_2488|M.thermoresistible__bu      --------------------------------------------------
Mb0248c|M.bovis_AF2122/97           GGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLK
Rv0242c|M.tuberculosis_H37Rv        GGAGRVVEPLRAALEKDYDLVGNNLGGRWADSFGGLVFDATGITEPAGLK
MMAR_0503|M.marinum_M               GGEGRVAEPLRAALAKDYDQVSNNLGGRWADSFGGLVFDATGITDPAGLK
MUL_1166|M.ulcerans_Agy99           GGEGRVAEPLRAALAKDYDQVSNNLGGRWADSFGGLVFDATGITDPAGLK
MLBr_02565|M.leprae_Br4923          GGDGRLVEPLRATLEKDYDLVSNNLGGRWTDSFGGLVFDATGITAPAELK
MAV_5088|M.avium_104                --------------------------------------------------
                                                                                      

MAB_2032|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0789|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1263|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4117|M.smegmatis_MC2_155      --------------------------------------------------
TH_2488|M.thermoresistible__bu      --------------------------------------------------
Mb0248c|M.bovis_AF2122/97           GLHEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGK
Rv0242c|M.tuberculosis_H37Rv        GLHEFFTPVLRNLGRCGRVVVVGGTPEAAASTNERIAQRALEGFTRSLGK
MMAR_0503|M.marinum_M               GLHDFFKPVLRNLGASARVVVVGTTPDAIDNSHERIAQRALEGFTRSLAK
MUL_1166|M.ulcerans_Agy99           GLHDFFKPVLRNLGASARVVVVGTTPDAIDNSHERIAQRALEGFTRSLAK
MLBr_02565|M.leprae_Br4923          GLHNFFTPLLRNLGRCARVVVIGTTPDATTSTDERIAQRALEGFSRSLGK
MAV_5088|M.avium_104                --------------------------------------------------
                                                                                      

MAB_2032|M.abscessus_ATCC_1997      --------------------------------------------------
Mvan_0789|M.vanbaalenii_PYR-1       --------------------------------------------------
Mflv_1263|M.gilvum_PYR-GCK          --------------------------------------------------
MSMEG_4117|M.smegmatis_MC2_155      --------------------------------------------------
TH_2488|M.thermoresistible__bu      --------------------------------------------------
Mb0248c|M.bovis_AF2122/97           ELRRGATTALVYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADD
Rv0242c|M.tuberculosis_H37Rv        ELRRGATTALVYLSPDAKPAATGLESTMRFLLSAKSAYVDGQVFSVGADD
MMAR_0503|M.marinum_M               ELRRGSTAALVYLSPEAKPAATGLESTVRFILSAKSAYVDGQVFYVGAAD
MUL_1166|M.ulcerans_Agy99           ELRRASTAALVYLSPEAKPAATGLESTVRFILSAKSAYVDGQVFYVGAAD
MLBr_02565|M.leprae_Br4923          ELRRGATVALVYLSPDAKPAATGLESTMRFILSAKSAYVNGQVFYVGAAD
MAV_5088|M.avium_104                -----------------------------------------------MAE
                                                                                      

MAB_2032|M.abscessus_ATCC_1997      -----MSGKEFEGQVALVTGASRGIGRSIALALAEHGADIALHYGNSKPA
Mvan_0789|M.vanbaalenii_PYR-1       -----MT---LNGKVALVTGAARGIGRGIALRLARDGADIALVDVLP-EG
Mflv_1263|M.gilvum_PYR-GCK          ---MSDR-FSMEGRVAVITGGGTGIGRASALVLAEHGADVVLA-GRRAEP
MSMEG_4117|M.smegmatis_MC2_155      ---MTPRPENLEGKVAIVTGAGRGLGRAMAKGLVDAGAAVTVA-ARTSAE
TH_2488|M.thermoresistible__bu      --------MEFQGLHVLVTGGTGGIGLACARAFAEAGAEVTVT-GRDAG-
Mb0248c|M.bovis_AF2122/97           STPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHVVAIDVE-SAA
Rv0242c|M.tuberculosis_H37Rv        STPPADWEKPLDGKVAIVTGAARGIGATIAEVFARDGAHVVAIDVE-SAA
MMAR_0503|M.marinum_M               STPPADWDRPLEGKVAIVTGAARGIGQTIAEVFARDGASVVAIDVE-SAA
MUL_1166|M.ulcerans_Agy99           STPPADWDRPLEGKVAIVTGAARGIGQTIAEVFARDGASVVAIDVE-SAA
MLBr_02565|M.leprae_Br4923          STPPTNWDRPLENKVAIVTGAARGIGAAIAEVVARDGARVVAIDVE-SAA
MAV_5088|M.avium_104                S--------LLLGKVAVVTGAGQGIGREIARALHRHGARVVLADLDGSAA
                                              : .  .::**.  *:*   *  .   ** :.         

MAB_2032|M.abscessus_ATCC_1997      AEEVAEKISALGRRVLLCQGDIADPAVPELLADTVHAEFGRIDVLVNNAG
Mvan_0789|M.vanbaalenii_PYR-1       LDGVADKIAGIGGKTTMFVADVSDREQVFAAVDHAAAALGGFDIMVNNAG
Mflv_1263|M.gilvum_PYR-GCK          LKETAAEVEALGRRALAVPTDVTDADACQALVDTTLAEFGRLDVLLNNAG
MSMEG_4117|M.smegmatis_MC2_155      LESFVADAKAAGGQALACSTDITDEASVERLVDATVETFGRVDILVNNSG
TH_2488|M.thermoresistible__bu      ---RGAAAAGAHPRLRFIRGDLADLASVQNLIR----YADAVDVLVNNAA
Mb0248c|M.bovis_AF2122/97           ENLAETASKVGG--TALWLDVTADDAVDKISEHLRDHHGGKADILVNNAG
Rv0242c|M.tuberculosis_H37Rv        ENLAETASKVGG--TALWLDVTADDAVDKISEHLRDHHGGKADILVNNAG
MMAR_0503|M.marinum_M               DALAETAASVGG--TPLWLDVTADDAVDKITEHLRDHHGGKADILVNNAG
MUL_1166|M.ulcerans_Agy99           DALAETAASVGG--TPLWLDVTADDAVDKITEHLRDHHGGKADILVNNAG
MLBr_02565|M.leprae_Br4923          EALDETANRVGG--TTLSLDVTADDAVDKITEHLHDYQGGHADILVNNAG
MAV_5088|M.avium_104                RSAAAQIDDSGANCTGLACDVTSEEQVGALVAGTVREHGG-LDVFVNNAG
                                                          ::               .  *:::**:.

MAB_2032|M.abscessus_ATCC_1997      THGAGLLLDIAPDYLEETVATNLLGPIRMTKAVVAHMLGQ------RYGR
Mvan_0789|M.vanbaalenii_PYR-1       IALVGPISDVTPEQIEKLWAINVNGVLWGTQAAVAKFKELKNKDKGRVSR
Mflv_1263|M.gilvum_PYR-GCK          GGETKSLMKWTDDEWHHVLDLNLSSAWYLSRAAAKPMIAQ------GSGA
MSMEG_4117|M.smegmatis_MC2_155      IVATTPLIEQSADEWDRVVATNLRGTFLATRAVGRHLVAQ------RSGK
TH_2488|M.thermoresistible__bu      SFPGALTVEQDAESFTRTFATNVTGTYFLTAGLIPGMLAR------GRGS
Mb0248c|M.bovis_AF2122/97           ITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIG------EGGR
Rv0242c|M.tuberculosis_H37Rv        ITRDKLLANMDDARWDAVLAVNLLAPLRLTEGLVGNGSIG------EGGR
MMAR_0503|M.marinum_M               ITRDKLLANMDDARWDSVIAVNLLAPLRLTEGLVGNGSIG------AGGR
MUL_1166|M.ulcerans_Agy99           ITRDKLLANMDDARWDSVIAVNLLAPLRLTEGLVGNGSIG------AGGR
MLBr_02565|M.leprae_Br4923          ITRDKLLANMDDCRWDAVLEVNLLAPQRLTEGLVGNGSIS------KGGR
MAV_5088|M.avium_104                ITRDASLKRMTVADFDAVIAVHLRGTWLGVREAAAVMRER------KTGS
                                                         :: .                       . 

MAB_2032|M.abscessus_ATCC_1997      IINISSVAADKPDSGQSTYAATKGGLESFTKAIAVEFASRNIISNAVAPG
Mvan_0789|M.vanbaalenii_PYR-1       IINASSIAGHDGFAMLGPYSATKFAVRALTQAAAKEHAADGITVNAYCPG
Mflv_1263|M.gilvum_PYR-GCK          IVNISSGAGLLAMPQAPIYGAAKAGLQNLTGSMAAAWTRKGVRVNCIACG
MSMEG_4117|M.smegmatis_MC2_155      VINIASNFALQGVANHAAYSASKAGVIAFTRSMAIEWARDNIQVNAIAPG
TH_2488|M.thermoresistible__bu      IVNITSMVATKAVPGASVYSSSKAAVESLTRSWAVEFAAHGIRVNAVAPG
Mb0248c|M.bovis_AF2122/97           VIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPG
Rv0242c|M.tuberculosis_H37Rv        VIGLSSIAGIAGNRGQTNYATTKAGMIGITQALAPGLAAKGITINAVAPG
MMAR_0503|M.marinum_M               VIGLSSIAGIAGNRGQTNYGATKAGMIGIAQALAPSLAEKDITINAVAPG
MUL_1166|M.ulcerans_Agy99           VIGLSSIAGIAGNRGQTNYGATKAGMIGIAQALAPSLAEKDITINAVAPG
MLBr_02565|M.leprae_Br4923          VIVLSSMAGIAGNRGQTNYATAKAGVIGLTQALAPGLAEKGITINAVAPG
MAV_5088|M.avium_104                IVNMSSLSGKAGNPGQTNYSAAKAGIVGLTKAAAKELAHHNVRVNAIQPG
                                    ::  :*  .         *.::* .:  :: : *   :  .:  *.   *

MAB_2032|M.abscessus_ATCC_1997      VVYTDM--------AEITRTHVPATFERLKAQILAKDFAKPEIVADAVLY
Mvan_0789|M.vanbaalenii_PYR-1       VVGTDMWVEIDKRFAELTGAAEGETYDKFVGGIALGRAETPDDVAGFVSY
Mflv_1263|M.gilvum_PYR-GCK          AVRTPG--------LEADAKRQGFDIDMIGQTNGSGRIAEPDEIGYGVLF
MSMEG_4117|M.smegmatis_MC2_155      YFATS---------LNADMRADADMAAKVVRAIPARRMGEPEELTSWLLL
TH_2488|M.thermoresistible__bu      PTSTDG--------VATEWG---ETNEALGRALPIGRTADPDEIAQAVVF
Mb0248c|M.bovis_AF2122/97           FIETQM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY
Rv0242c|M.tuberculosis_H37Rv        FIETQM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY
MMAR_0503|M.marinum_M               FIETKM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY
MUL_1166|M.ulcerans_Agy99           FIETKM-----------TAAIPLATREVGRRLNSLLQGGQPVDVAEAIAY
MLBr_02565|M.leprae_Br4923          FIETQM-----------TAAIPLATREVGRRLNSLLQGGLPVDVAETIAY
MAV_5088|M.avium_104                LIRTPM-----------TAAMPPDVFAEREAAVPMKRAGEPEEVAGAVVF
                                       *                                    *  :   :  

MAB_2032|M.abscessus_ATCC_1997      LASPHNTYITGEVLHIDGGYKMK--
Mvan_0789|M.vanbaalenii_PYR-1       LAGPDADYMTGQSGLIDGGLVYR--
Mflv_1263|M.gilvum_PYR-GCK          FASDASSYCSGQTLYMHGGPGPAGV
MSMEG_4117|M.smegmatis_MC2_155      LAGSASDFMTGEVIVIDGGQSVR--
TH_2488|M.thermoresistible__bu      LASSRASFITGAVLHVDGGGIAV--
Mb0248c|M.bovis_AF2122/97           FASPASNAVTGNVIRVCGQAMIGA-
Rv0242c|M.tuberculosis_H37Rv        FASPASNAVTGNVIRVCGQAMIGA-
MMAR_0503|M.marinum_M               FASPASNAVTGNVIRVCGQAMIGA-
MUL_1166|M.ulcerans_Agy99           FASPASNAVTGNVIRVCGQAMIGA-
MLBr_02565|M.leprae_Br4923          FAIPASNAVTGNVIRVCGQAMLGA-
MAV_5088|M.avium_104                LASELSSYITGTVLGVGGGRYM---
                                    :*       :*    : *