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M. ulcerans Agy99 MUL_0336 (-)

annotation: short chain dehydrogenase
coordinates: 343471 - 344274
length: 267

VDELAGKIAIVTGGASGIGRATVARFIAEGARVVIADVEEERGESLAAALGADAMFCRTDVSQPEQVAAV
VAAAVDNFGGLHVMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHGGGSIVNLT
SIGGIQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNAIAPGNIPTPLLASSAAGLDQEQVERFTAQ
IRQTMREDRPLKREGTPEDIAEAALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR*
Operon Prediction Model: Genebank

Paralogs
speciesidgenee-valueidentity (len)annotation
M. ulcerans Agy99MUL_0336--100% (267)short chain dehydrogenase
M. ulcerans Agy99MUL_1037fabG33e-4139.53% (253) 20-beta-hydroxysteroid dehydrogenase FabG3
M. ulcerans Agy99MUL_3898fabG2e-4039.11% (248) 3-ketoacyl-(acyl-carrier-protein) reductase

Closest Orthologs (e-value cutoff: 1e-4)
speciesidgenee-valueidentity (len)annotation
M. bovis AF2122 / 97Mb1385fabG2e-4340.94% (254) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCKMflv_2415-5e-9967.92% (265) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37RvRv1350fabG2e-4340.94% (254) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923MLBr_01807fabG16e-2530.28% (251) 3-oxoacyl-
M. abscessus ATCC 19977MAB_4680c-4e-3838.22% (259) putative short-chain dehydrogenase/reductase
M. marinum MMMAR_4765-1e-14598.50% (267) short chain dehydrogenase
M. avium 104MAV_0886-1e-11679.40% (267) short-chain dehydrogenase/reductase SDR
M. smegmatis MC2 155MSMEG_4859-1e-10974.24% (264) oxidoreductase, short chain dehydrogenase/reductase family
M. thermoresistible (build 8)TH_3420-1e-10873.28% (262) PUTATIVE oxidoreductase, short chain dehydrogenase/reductase
M. vanbaalenii PYR-1Mvan_4237-1e-10170.57% (265) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb1385|M.bovis_AF2122/97            --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
Rv1350|M.tuberculosis_H37Rv         --------------MASLLNARTAVITGGAQGLGLAIGQRFVAEGARVVL
MUL_0336|M.ulcerans_Agy99           --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MMAR_4765|M.marinum_M               --------------MVDELAGKIAIVTGGASGIGRATVARFIAEGARVVI
MAV_0886|M.avium_104                --------------MVNELAGKVAIVTGGASGIGRGIVERFVAEGARVVI
MSMEG_4859|M.smegmatis_MC2_155      ---------------MSELAGRVAVVTGGASGLGEGLVRRFVAEGAQVMI
TH_3420|M.thermoresistible__bu      -----------VTERAGELAGKVAVVTGGAAGLGAGLARRFVAEGAKVLI
Mflv_2415|M.gilvum_PYR-GCK          ---------------MTELAGKVAVVTGGASGIGRGIAARFAAEGAAVVI
Mvan_4237|M.vanbaalenii_PYR-1       ---------------MTELVGKVAIVTGGASGIGRGIAERFAAEGARVVI
MAB_4680c|M.abscessus_ATCC_199      -----------MNGNSALLQGKNVIVTGGARGLGAAFSRHIVSQGGRVVI
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      : .:  ::***  *:* .   :: ::*  * :

Mb1385|M.bovis_AF2122/97            GDVNLEATEVAAKRLG-GDDVALAVRCDVTQADDVDILIRTAVERFGGLD
Rv1350|M.tuberculosis_H37Rv         GDVNLEATEVAAKRLG-GDDVALAVRCDVTQADDVDILIRTAVERFGGLD
MUL_0336|M.ulcerans_Agy99           ADVEEERGESLAAAL---GADAMFCRTDVSQPEQVAAVVAAAVDNFGGLH
MMAR_4765|M.marinum_M               ADVEEERGESLAAAL---GADAMFCRTDVSQPEQVAAVVAAAVENFGGLH
MAV_0886|M.avium_104                ADIETERGERLAAEL---GGEAVFRRTDVSDIEQVGALVAAAVEKFGGLH
MSMEG_4859|M.smegmatis_MC2_155      GDVDKDRGTALAEEL---GAHTEFLTTDVADQEQVAALVSAGVERFGGLH
TH_3420|M.thermoresistible__bu      GDVDTGNGAKLAAEL---GADAEFVEADVADLDQVSGLVSTAVERFGGLH
Mflv_2415|M.gilvum_PYR-GCK          ADVRDDLGEALVRELNESGAKTVYRHTDVGDQAQVADLVSSTVETFGALN
Mvan_4237|M.vanbaalenii_PYR-1       ADVRDDLGEPLAAELNSRGAKTVYRHTDVGDQRQVAELVAAAVDTFGGLD
MAB_4680c|M.abscessus_ATCC_199      ADVLDGDGRQLAAEL---GDAARFTHLDVTDAEQWRELIDTTLAGFGTIT
MLBr_01807|M.leprae_Br4923          THRASVVP-----------DWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
                                     .                         ** :       . :     * : 

Mb1385|M.bovis_AF2122/97            VMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRERK
Rv1350|M.tuberculosis_H37Rv         VMVNNAGITRDATMRTMTE--EQFDQVIAVHLKGTWNGTRLAAAIMRERK
MUL_0336|M.ulcerans_Agy99           VMVNNAGVSGAMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHG
MMAR_4765|M.marinum_M               VMVNNAGVSGVMHRRFLDDDLADFHRVMAVNVLGVMAGTRDAARHMAAHG
MAV_0886|M.avium_104                VMVNNAGISSPLRR-LLDDDLADFHRVMGVNVLGVMAGTRDAARHMADNG
MSMEG_4859|M.smegmatis_MC2_155      VMVNNAGVSGTMHRRFLDDDLADFHKVMGVNVLGVMAGTREAARYMADNG
TH_3420|M.thermoresistible__bu      VMVNNAGISGTMHRSLLDDDLADFDRVMRINVRAVMAGTRDAARHMAEHG
Mflv_2415|M.gilvum_PYR-GCK          VMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAARHMADHG
Mvan_4237|M.vanbaalenii_PYR-1       VMVNNAGISSPLRKGLFHEDLEEFDRVMRVNLLGVMAGTRDAGRYMADHG
MAB_4680c|M.abscessus_ATCC_199      GLVNNAGISS--AAMVADEPLEHFRKVIEINLVGVFIGMQAVIPAMRAHG
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMRMSE--EQFQKVIDVNLTGVFRVAKLASRNMIKQR
                                     :* ***::         :   .* :*: ::: ..    : .   *  . 

Mb1385|M.bovis_AF2122/97            RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
Rv1350|M.tuberculosis_H37Rv         RGAIVNMSSVSGKVGMVGQTNYSAAKAGIVGMTKAAAKELAHLGIRVNAI
MUL_0336|M.ulcerans_Agy99           GGSIVNLTSIGGIQAGGGVMTYRASKGAVIQFTKSAAIELAHYEIRVNAI
MMAR_4765|M.marinum_M               GGSIVNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHYEIRVNAI
MAV_0886|M.avium_104                GGAIINLTSIGGIQAGGGVMTYRASKAAVIQFTKAAAIELARYDIRVNAI
MSMEG_4859|M.smegmatis_MC2_155      GGSILNLTSIGGIQAGGGVMTYRASKAAVIQFTKSAAIELAHHEIRVNAI
TH_3420|M.thermoresistible__bu      GGSIINLTSIGGIQAGGGVQTYRASKAAVIQFTKSAAIELAHHEIRVNAL
Mflv_2415|M.gilvum_PYR-GCK          GGSVINLGSIGGIQAGGGVSTYRASKAAIIHFTKCAAIELAHYEVRVNCL
Mvan_4237|M.vanbaalenii_PYR-1       GGSIINLGSIGGIQAGGGVSTYRASKAAIIHFTKCAAIELAHYEVRVNCL
MAB_4680c|M.abscessus_ATCC_199      CGSIVNISSAAGLVGLALTSGYGASKWGVRGLSKVAAIELGRERIRVNSV
MLBr_01807|M.leprae_Br4923          FGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANVV
                                     *  : : *  *  .      * *:* .:  :::  * **.   : .* :

Mb1385|M.bovis_AF2122/97            APGLIRSAMT------------EAMPQRIWDQKLAEVPMGRAGEPSEVAS
Rv1350|M.tuberculosis_H37Rv         APGLIRSAMT------------EAMPQRIWDQKLAEVPMGRAGEPSEVAS
MUL_0336|M.ulcerans_Agy99           APGNIPTPLLASSAAGLDQEQVERFTAQIRQTMREDRPLKREGTPEDIAE
MMAR_4765|M.marinum_M               APGNIPTPLLASSAAGMDQEQVERFTAQIRQTMREDRPLKREGTPEDIAE
MAV_0886|M.avium_104                APGNIPTPILGKSAGDMDPEQRERFEARIREGMREDRPLKREGTPDDVAE
MSMEG_4859|M.smegmatis_MC2_155      APGNIRTAIVAKSASEEDRQRIEEFEANIRAQMRADRPLKREGTVEDVAE
TH_3420|M.thermoresistible__bu      APGNIRTAIVRKSATGADLERLERFEARIRQQMRDDRPLKREGTVEDVAE
Mflv_2415|M.gilvum_PYR-GCK          APGNIPTPILASSATDEDRERLEKFEARIRQQMRDDRPLKREGTADDVAE
Mvan_4237|M.vanbaalenii_PYR-1       APGNIPTPILASSATDEDRERLERFEARIRRQMRDDRPLKREGTAEDVAE
MAB_4680c|M.abscessus_ATCC_199      HPGVIYTPMTAK----------EGFRE--GEGNMPIAAMGRVGNADEVAG
MLBr_01807|M.leprae_Br4923          APGFIDTEMTR------------AMDSKYQEAALQAIPLGRIGAVEEIAG
                                     ** * : :               :            .: * *  .::* 

Mb1385|M.bovis_AF2122/97            VAVFLASDLSSYMTGTVLDVTG----GRFI-----------
Rv1350|M.tuberculosis_H37Rv         VAVFLASDLSSYMTGTVLDVTG----GRFI-----------
MUL_0336|M.ulcerans_Agy99           AALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MMAR_4765|M.marinum_M               AALYFAGERSRYVTGTVLPVDGGTVAGKVIRRSR-------
MAV_0886|M.avium_104                AALYFATERSRYVTGTVLPVDGGTSAGKAMRSKRQG-----
MSMEG_4859|M.smegmatis_MC2_155      AALYFATDRSRYVTGTVLPIDGGTVAGKVIVRKEKR-----
TH_3420|M.thermoresistible__bu      AALYFAGDRSRYVTGTVLPIDGGTVAGKVIARKSHAE----
Mflv_2415|M.gilvum_PYR-GCK          AALYLATDRSRYVTGTVLPIDGGTVAGKVIVRKPKDQQ---
Mvan_4237|M.vanbaalenii_PYR-1       AALYLATDRSRYITGTVLPVDGGTVAGKVIVRKPPPAEAAT
MAB_4680c|M.abscessus_ATCC_199      AVAYLLSDAASYVTGAELAVDGGWTAGPTLTTITGQ-----
MLBr_01807|M.leprae_Br4923          AVSFLASEDAGYISGAVIPVDGGLGMGH-------------
                                    .. ::  : : *::*: : : *    *