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FDLQGRSVVVTGGTKGIGRGIATVFARAGANVAVAGRSTADIDACVADLDQLGSGKVIGVQTDVSDRAQC DALAGRAVEEFGGIDVVCANAGVFPDAPLATMTPEQLNGIFAVNVNGTFYAVQACLDALIASGSGRVVLT SSITGPITGYPGWSHYGATKAAQLGFMRTAAIELAPHKITVNAIMPGNIMTEGLLENGEEYIASMARSIP AGALGTPEDIGHLAAFLATKEAGYITGQAIAVDGGQVLPESLDAIAT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0779 | - | - | 100% (258) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0269 | - | 1e-84 | 60.63% (254) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_4117 | - | 6e-37 | 34.41% (247) | 2-deoxy-D-gluconate 3-dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 1e-44 | 38.98% (254) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1235 | - | 2e-88 | 62.20% (254) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1928c | - | 1e-44 | 38.98% (254) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-33 | 35.27% (241) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 1e-105 | 73.05% (256) | short chain dehydrogenase |
| M. marinum M | MMAR_2849 | - | 6e-40 | 36.11% (252) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2775 | - | 5e-42 | 35.32% (252) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2589 | - | 2e-39 | 39.43% (246) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_0327 | - | 1e-32 | 35.51% (245) | oxidoreductase |
| M. vanbaalenii PYR-1 | Mvan_5573 | - | 2e-88 | 62.60% (254) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
MSMEG_0779|M.smegmatis_MC2_155 --------------MFD-LQGRSVVVTGGTKGIGRGIATVFARAGANVAV
MAB_0952|M.abscessus_ATCC_1997 -MVVESAEPAERKVMFD-LSARSVLVTGGTKGIGRGIATVFARAGANVAV
Mflv_1235|M.gilvum_PYR-GCK --------------MFTSLQGRSAAVTGGSKGIGRGIAETFARAGINVVI
Mvan_5573|M.vanbaalenii_PYR-1 --------------MFNSLQGRSAIVTGGSKGIGRGIAETFARAGVNVVI
TH_2589|M.thermoresistible__bu ------VDRQTFDKLFD-MTGRTVVVTGGTRGIGLALAEGYVLAGARVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
Mb1963c|M.bovis_AF2122/97 ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
MMAR_2849|M.marinum_M ----------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQVAV
MAV_2775|M.avium_104 ------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGARVAI
MUL_0327|M.ulcerans_Agy99 ---------MAIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAI
: .: :**. *** :* * :.:
MSMEG_0779|M.smegmatis_MC2_155 AGRSTADIDACVADLDQLGSGKVIGVQTDVSDRAQCDALAGRAVEEFGGI
MAB_0952|M.abscessus_ATCC_1997 AARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGAL
Mflv_1235|M.gilvum_PYR-GCK TARTQDDIDATVADLAGL-AGTVTGVAADVTSPEDCRRVVETAIERHGGL
Mvan_5573|M.vanbaalenii_PYR-1 TGRTQADIDGTVAGLAGL-PGTVTGVAADVTSPEDCRRVVATATERNGGL
TH_2589|M.thermoresistible__bu ASRKSDACERAAAHLRAL-GGDAIGVPTHLGDIDACEALVRRTVDEFGGI
MLBr_01807|M.leprae_Br4923 THRAS------------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPV
Mb1963c|M.bovis_AF2122/97 AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Rv1928c|M.tuberculosis_H37Rv AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
MMAR_2849|M.marinum_M AARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGELGGI
MAV_2775|M.avium_104 AARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAELGGI
MUL_0327|M.ulcerans_Agy99 WERDPQTCAQAAAELGGLG------IATDVRSGDQVDAALQRTQAELGAV
* : .: . * :
MSMEG_0779|M.smegmatis_MC2_155 DVVCANAGVFPDAPLATMTPEQLNGIFAVNVNGTFYAVQACLDALIASGS
MAB_0952|M.abscessus_ATCC_1997 DVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTASGR
Mflv_1235|M.gilvum_PYR-GCK DIVCPNAGIFPSGRIADLTPDDIEQVLGVNFKGTVYIVQAALDALTASGH
Mvan_5573|M.vanbaalenii_PYR-1 DIVCANAGIFPSGRLQDLTPEDIEQVLGVNFKGTVYIVQAALDALTASGH
TH_2589|M.thermoresistible__bu DVLVNNAANALTQPLGELTVDAWTKSFEVNLRGPVFLVQAALPHLKTSPH
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
Mb1963c|M.bovis_AF2122/97 DIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQ
Rv1928c|M.tuberculosis_H37Rv DIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQ
MMAR_2849|M.marinum_M DIAVCNAGIVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMVDQGL
MAV_2775|M.avium_104 DIAVCNAGIISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVRQGR
MUL_0327|M.ulcerans_Agy99 TILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAGL
: *.. : . *. . .: :
MSMEG_0779|M.smegmatis_MC2_155 -GRVVLTSSITGPITGYP-GWSHYGATKAAQLGFMRTAAIELAPHKITVN
MAB_0952|M.abscessus_ATCC_1997 -GRVILTSSITGPVTGYP-GWSHYGASKAAQLGFMRTAAIELAPRGVTVN
Mflv_1235|M.gilvum_PYR-GCK -GRVIITSSITGPITGFP-GWSHYGASKAAQLGFLRTAAIELAPKKITVN
Mvan_5573|M.vanbaalenii_PYR-1 -GRVIITSSITGPITGFP-GWSHYGASKAAQMGFLRTAAIELAPKKITVN
TH_2589|M.thermoresistible__bu -AAVLNMVSVG-AFLFSP-GTAMYSAGKAALMSFTRSMAAQFAPLGIRVN
MLBr_01807|M.leprae_Br4923 -GRYIFMGSVV-GLSGVP-GQANYAASKSGLIGMARSLARELGSRSITAN
Mb1963c|M.bovis_AF2122/97 GGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVN
Rv1928c|M.tuberculosis_H37Rv GGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVN
MMAR_2849|M.marinum_M GGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQIRVN
MAV_2775|M.avium_104 GGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHDIRVN
MUL_0327|M.ulcerans_Agy99 PGSIMAITSIEG--VRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIRVN
. : *: . . * : *:. : :: * ::. : .*
MSMEG_0779|M.smegmatis_MC2_155 AIMPGNIMTEGLLENGEEYIASMAR-SIPAGALGTPEDIGHLAAFLATKE
MAB_0952|M.abscessus_ATCC_1997 AILPGNILTEGLVDMGEEYISGMAR-SIPMGMLGSPVDIGHLAAFLATDE
Mflv_1235|M.gilvum_PYR-GCK AVLPGNILTEGLVEMGQSYIDQMAA-AVPAGKLGEVADIGNAALFFATDE
Mvan_5573|M.vanbaalenii_PYR-1 AVLPGNIITEGLVEMGQTYMDQMAA-SVPAGKLGEVADIGNAALFFATDE
TH_2589|M.thermoresistible__bu ALAPGPVDTDMMRNNPQEVVDMMAG-ATLMKRLATPDEMVGAALLLTSDA
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSKYQEAALQ-AIPLGRIGAVEEIAGAVSFLASED
Mb1963c|M.bovis_AF2122/97 SVSPGYILTELVEPYTEYQPLWEP--KIPLGRLGRPEELAGLYLYLASEA
Rv1928c|M.tuberculosis_H37Rv SVSPGYILTELVEPYTEYQPLWEP--KIPLGRLGRPEELAGLYLYLASEA
MMAR_2849|M.marinum_M SVSPGYIRTELVEPLADYHALWEP--KIPLGRMGRPEELTGLYLYLASAA
MAV_2775|M.avium_104 SVSPGYIRTELVEPLHEYHRQWQP--KIPLGRMGRPDELAGIYLYLASAA
MUL_0327|M.ulcerans_Agy99 AIAPDITMTEGLAQLGGAAALERIGSLVPLGRPGDVDEIASVAVFLASDM
: *. *: . :: :::
MSMEG_0779|M.smegmatis_MC2_155 AGYITGQAIAVDGGQVLPESLDAIAT---------
MAB_0952|M.abscessus_ATCC_1997 AGYITGQAIVVDGGQVLPESPDAVNP---------
Mflv_1235|M.gilvum_PYR-GCK AAYITGQSLVVDGGQILPESPEALADL--------
Mvan_5573|M.vanbaalenii_PYR-1 ASYITGQSLVVDGGQILPESPEALADL--------
TH_2589|M.thermoresistible__bu GSYITGTVLIADGGGTPR-----------------
MLBr_01807|M.leprae_Br4923 AGYISGAVIPVDGGLGMGH----------------
Mb1963c|M.bovis_AF2122/97 SSYMTGSDIVIDGGYTCP-----------------
Rv1928c|M.tuberculosis_H37Rv SSYMTGSDIVIDGGYTCP-----------------
MMAR_2849|M.marinum_M SSYMTGSDIVIDGGYTCP-----------------
MAV_2775|M.avium_104 SSYMTGSDIVIDGGYSCP-----------------
MUL_0327|M.ulcerans_Agy99 ARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG
. *::* : ***