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M. thermoresistible (build 8) TH_2589 (-)

annotation: short-chain dehydrogenase/reductase SDR
coordinates: 2301547 - 2302317
length: 257

aa seq not available

Operon Prediction Model: Genebank

Paralogs

species id gene e-value identity (len) annotation
M. thermoresistible (build 8) TH_2589 - - 100% (257) short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_4266 - 7e-40 38.10% (252) PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8) TH_3708 - 9e-40 36.33% (245) PUTATIVE short-chain dehydrogenase/reductase SDR

Closest Orthologs (e-value cutoff: 1e-4)

species id gene e-value identity (len) annotation
M. bovis AF2122 / 97 Mb2788c fabG 3e-40 38.68% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. gilvum PYR-GCK Mflv_4818 - 1e-108 76.95% (256) short-chain dehydrogenase/reductase SDR
M. tuberculosis H37Rv Rv2766c fabG 3e-40 38.68% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. leprae Br4923 MLBr_01807 fabG1 1e-24 30.67% (238) 3-oxoacyl-
M. abscessus ATCC 19977 MAB_0833 - 2e-97 69.05% (252) Short-chain dehydrogenase/reductase
M. marinum M MMAR_1952 fabG 7e-38 37.04% (243) short-chain type dehydrogenase/reductase
M. avium 104 MAV_3655 fabG 2e-41 38.68% (243) 3-ketoacyl-(acyl-carrier-protein) reductase
M. smegmatis MC2 155 MSMEG_1740 - 1e-109 75.78% (256) dehydrogenase/reductase SDR family protein member 4
M. ulcerans Agy99 MUL_0478 - 1e-37 38.02% (242) short chain dehydrogenase
M. vanbaalenii PYR-1 Mvan_1624 - 1e-112 79.69% (256) short-chain dehydrogenase/reductase SDR

CLUSTAL 2.0.9 multiple sequence alignment


Mb2788c|M.bovis_AF2122/97           -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
Rv2766c|M.tuberculosis_H37Rv        -------------MTSLDLTGRTAIITGASRGIGLAIAQQLAAAGAHVVL
MMAR_1952|M.marinum_M               -------------MTSLDLTGRTAIITGASRGIGLAIAQRLAGAGANVVL
MAV_3655|M.avium_104                -------------MTSQDLTGRTAIITGASRGIGLAIAQQLAAAGANVVL
Mflv_4818|M.gilvum_PYR-GCK          -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYALAGARVVV
Mvan_1624|M.vanbaalenii_PYR-1       -------MDRASFDRLFDMTDRTVVVTGGTRGIGLALAEGYVLAGARVVV
MSMEG_1740|M.smegmatis_MC2_155      -------MDRQRFERLFDMSDRTVIVTGGTRGIGLSLAEGFVLAGARVVV
TH_2589|M.thermoresistible__bu      -------VDRQTFDKLFDMTGRTVVVTGGTRGIGLALAEGYVLAGARVVV
MAB_0833|M.abscessus_ATCC_1997      -------MNRETFSRLFDLTGRTAIVTGGTRGIGRALAEGYACAGANVVV
MUL_0478|M.ulcerans_Agy99           ---------------MGQFENKVAIVTGAAQGIGQAYADALAREGARVVV
MLBr_01807|M.leprae_Br4923          MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
                                                      : .:  ::**. :*** : *   .  * .*.:

Mb2788c|M.bovis_AF2122/97           TARRQEAADEAAAQV---GDRALGVGAHAVDEDAARRCVDLTLERFGSVD
Rv2766c|M.tuberculosis_H37Rv        TARRQEAADEAAAQV---GDRALGVGAHAVDEDAARRCVDLTLERFGSVD
MMAR_1952|M.marinum_M               TARKQESADAAAAEV---GERAVGVGAHAVDEEAARGCVDLALERFGSVD
MAV_3655|M.avium_104                TARKQEAADEAAAQV---GPQALGVGAHAVDEDAARQCVQLTLERFGSVD
Mflv_4818|M.gilvum_PYR-GCK          ASRKADACEQAAHHLRELGAQAIGVPTHLGQVDDLGALVERTVAEFGGLD
Mvan_1624|M.vanbaalenii_PYR-1       ASRKADACEETARHLRELGGSAIGVPTHLGEVDDLGALVERTVAEFGGVD
MSMEG_1740|M.smegmatis_MC2_155      ASRKPDACETAAAHLRELGGDAVGVPAHTGDVDDLGAVVERAVSEFGGVD
TH_2589|M.thermoresistible__bu      ASRKSDACERAAAHLRALGGDAIGVPTHLGDIDACEALVRRTVDEFGGID
MAB_0833|M.abscessus_ATCC_1997      ASRKPEACTEAVERLRSLGARALGVPTHTGDIHSLEELVRATAEEFGGID
MUL_0478|M.ulcerans_Agy99           ADINAEAAEKTAKQIVADGGTAIHVPVDVSDEESARAMADRTVSEFGGID
MLBr_01807|M.leprae_Br4923          THRAS-----------VVPDWFFGVECDVTDNDAIGAAFKAVEEHQGPVE
                                    :                     . *  .  : .        .  . * ::

Mb2788c|M.bovis_AF2122/97           ILINNAG--TNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
Rv2766c|M.tuberculosis_H37Rv        ILINNAG--TNPAYGPLLEQDHARFAKIFDVNLWAPLMWTSLVVTAWMGE
MMAR_1952|M.marinum_M               ILINNAG--TNPAYGPLIEQDHARFTKIFDVNLWAPLMWTSLVVKAWMGE
MAV_3655|M.avium_104                ILVNNAG--TNPAYGPLIEQDHARFAKIFDVNLWAPLLWTSLAVKSWMGE
Mflv_4818|M.gilvum_PYR-GCK          VLVNNAANPLAQPFG---HMTVDALSKSFEVNLQGPVMLTQEALPHLKAS
Mvan_1624|M.vanbaalenii_PYR-1       VLVNNAANPLAQPFG---YMTVDALTKSFEVNLRGPVMLVQEALPHLKAS
MSMEG_1740|M.smegmatis_MC2_155      VVVNNAANALAQPLG---KMTPEAWAKSYEVNLRGPVFLVQHALPYLQKS
TH_2589|M.thermoresistible__bu      VLVNNAANALTQPLG---ELTVDAWTKSFEVNLRGPVFLVQAALPHLKTS
MAB_0833|M.abscessus_ATCC_1997      IVVNNAANALTEPVG---AFTVDGWDKSFGVNLRGPVFLVQAALPHLVAS
MUL_0478|M.ulcerans_Agy99           YLVNNAAIYGGMKLDLQLTVPLDYYKKFMSVNHDGVLVCTRAVYKHMAKR
MLBr_01807|M.leprae_Br4923          VLVANAGITSDMLIMR---MSEEQFQKVIDVNLTGVFRVAKLASRNMIKQ
                                     :: **.                   *   **  . .  .  .       

Mb2788c|M.bovis_AF2122/97           HGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
Rv2766c|M.tuberculosis_H37Rv        HGGAVVNTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-IRVNA
MMAR_1952|M.marinum_M               HGGVVINTASIGGMHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNA
MAV_3655|M.avium_104                HGGSIVNTASIGGLHQSPAMGMYNATKAALIHVTKQLALELSPR-VRVNA
Mflv_4818|M.gilvum_PYR-GCK          DHAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHDGIRVNA
Mvan_1624|M.vanbaalenii_PYR-1       EHAAVLNMVSVGAFIFAPMLSIYASMKAAMMSFTRSMAAEFVHHGIRVNA
MSMEG_1740|M.smegmatis_MC2_155      QNAAVLNMVSVGAFNFAPALSIYASSKAALMSVTRSMAAEFAPSGIRVNA
TH_2589|M.thermoresistible__bu      PHAAVLNMVSVGAFLFSPGTAMYSAGKAALMSFTRSMAAQFAPLGIRVNA
MAB_0833|M.abscessus_ATCC_1997      PHAAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNA
MUL_0478|M.ulcerans_Agy99           GGGAIVNQSSTAAWLYS---NFYGLAKVGVNGLTQQLSRELGGMKIRINA
MLBr_01807|M.leprae_Br4923          RFGRYIFMGSVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
                                      .  :   *  .         *   * .:   ::. : ::    :  *.

Mb2788c|M.bovis_AF2122/97           ICPGVVRTRLAE-ALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAA
Rv2766c|M.tuberculosis_H37Rv        ICPGVVRTRLAE-ALWKDHEDPLAATIALGRIGEPADIASAVAFLVSDAA
MMAR_1952|M.marinum_M               ICPGVVRTKLAE-ALWKDHEDPLAANIALGRIGEPVDVAEAVGFLVSDAA
MAV_3655|M.avium_104                IAPGVVRTRLAE-ALWKDHEDPLSSSIALGRIGEPIDVAAAVAFLVSDAA
Mflv_4818|M.gilvum_PYR-GCK          LAPGPVDTDMMR-KNPQEAIDGMVGGTLVGRLASADEMVGAALLLTSDAG
Mvan_1624|M.vanbaalenii_PYR-1       LAPGPVDTDMMR-KNPQEAIDGMVGGTLLGRLATPDEMVGAALLLTSDAG
MSMEG_1740|M.smegmatis_MC2_155      LAPGPVDTDMMR-KNPQEAIDAMTAGTLMKRLAHPDEMVGAALLLCSDAG
TH_2589|M.thermoresistible__bu      LAPGPVDTDMMR-NNPQEVVDMMAGATLMKRLATPDEMVGAALLLTSDAG
MAB_0833|M.abscessus_ATCC_1997      LAPGAIDTDMVR-KTPPAEVERMANTNHLKRLGLPDEMVGTALLLTSDAG
MUL_0478|M.ulcerans_Agy99           IAPGPIDTEATRTVTPGEFVKDMVKQIPLSRMGTPEDLVGMCLFLLGDQA
MLBr_01807|M.leprae_Br4923          VAPGFIDTEMTR-AMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
                                    :.** : *   .        .       : *:.   ::.    :* .: .

Mb2788c|M.bovis_AF2122/97           SWITGETMIIDGGLLLGNALGFRAAPSTEH
Rv2766c|M.tuberculosis_H37Rv        SWITGETMIIDGGLLLGNALGFRAAPSTEH
MMAR_1952|M.marinum_M               SWITGETMVIDGGLLLGSAAGFQSRPGSAS
MAV_3655|M.avium_104                SWITGETLVIDGGTVLGAAQGFRSAPTPS-
Mflv_4818|M.gilvum_PYR-GCK          SYITGQVIIADGGGTPR-------------
Mvan_1624|M.vanbaalenii_PYR-1       SYITGQVIIADGGGTPR-------------
MSMEG_1740|M.smegmatis_MC2_155      SYMTGQVVIVDGGGTPR-------------
TH_2589|M.thermoresistible__bu      SYITGTVLIADGGGTPR-------------
MAB_0833|M.abscessus_ATCC_1997      SYITGQTIIADGGLVAR-------------
MUL_0478|M.ulcerans_Agy99           SRITGQIFNVDGGQIIRS------------
MLBr_01807|M.leprae_Br4923          GYISGAVIPVDGGLGMGH------------
                                    . ::*  .  ***

species	id	gene	e-value	identity (len)	annotation
M. thermoresistible (build 8)	TH_2589	-	-	100% (257)	short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_4266	-	7e-40	38.10% (252)	PUTATIVE short-chain dehydrogenase/reductase SDR
M. thermoresistible (build 8)	TH_3708	-	9e-40	36.33% (245)	PUTATIVE short-chain dehydrogenase/reductase SDR