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AIDPADVLLNGRVAVVTGAGSGIGRGVAAGLAAFGASMAIWERDPQTCAQAAAELGGLGIATDVRSGDQV DAALQRTQAELGAVTILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAGLPGSIMA ITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIRVNAIAPDITMTEGLAQLGGAAALERIGSLV PLGRPGDVDEIASVAVFLASDMARYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0327 | - | - | 100% (268) | oxidoreductase |
| M. ulcerans Agy99 | MUL_3168 | - | 3e-42 | 39.76% (249) | short chain dehydrogenase |
| M. ulcerans Agy99 | MUL_0336 | - | 1e-32 | 35.55% (256) | short chain dehydrogenase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3589c | - | 1e-33 | 36.21% (243) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_2424 | - | 1e-103 | 70.04% (267) | short-chain dehydrogenase/reductase SDR |
| M. tuberculosis H37Rv | Rv3559c | - | 6e-34 | 36.21% (243) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 3e-25 | 32.77% (238) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0833 | - | 1e-34 | 34.98% (243) | Short-chain dehydrogenase/reductase |
| M. marinum M | MMAR_4756 | - | 1e-148 | 98.13% (268) | oxidoreductase |
| M. avium 104 | MAV_0894 | - | 1e-117 | 76.78% (267) | oxidoreductase, short chain dehydrogenase/reductase family |
| M. smegmatis MC2 155 | MSMEG_4850 | - | 1e-104 | 68.66% (268) | short-chain dehydrogenase/reductase SDR |
| M. thermoresistible (build 8) | TH_3505 | - | 1e-103 | 67.91% (268) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. vanbaalenii PYR-1 | Mvan_4228 | - | 1e-105 | 70.79% (267) | short-chain dehydrogenase/reductase SDR |
CLUSTAL 2.0.9 multiple sequence alignment
Mb3589c|M.bovis_AF2122/97 ---MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVV
Rv3559c|M.tuberculosis_H37Rv ---MNLSVAPKEIAGHGLLDGKVVVVTAAAGTGIGSATARRALAEGADVV
MUL_0327|M.ulcerans_Agy99 -----MAIDPADVL----LNGRVAVVTGAG-SGIGRGVAAGLAAFGASMA
MMAR_4756|M.marinum_M -----MAIDPADVL----LNGRVAVVTGAG-SGIGRGVAAGLAAFGASVA
MAV_0894|M.avium_104 -----MAIDPSDIL----LTDRVAVVTGAG-AGIGRGIAAGLAAFGARVA
Mflv_2424|M.gilvum_PYR-GCK -----MAITASDIL----LTGRVAVVTGGG-AGIGRGIAQGLAAFGASVA
Mvan_4228|M.vanbaalenii_PYR-1 -----MTIAPSDIL----LTGRVAVVTGGG-AGIGKGIAHGLAAFGASVA
MSMEG_4850|M.smegmatis_MC2_155 -----MAINPSDIL----LTGRVAVVTGGG-AGIGRGIAEGLAAFGARVA
TH_3505|M.thermoresistible__bu -----LTIAPADIL----LTDRVAVVTGGG-AGLGRGIAAGFAAFGARVA
MAB_0833|M.abscessus_ATCC_1997 ---MNRETFSRLFD----LTGRTAIVTGGT-RGIGRALAEGYACAGANVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGN-RGIGLAVARRLVADGHRVA
. : .: :**.. *:* . * . * :.
Mb3589c|M.bovis_AF2122/97 ISDHHERRLGETAAELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGR
Rv3559c|M.tuberculosis_H37Rv ISDHHERRLGETAAELSALGLGRVEHVVCDVTSTAQVDALIDSTTARMGR
MUL_0327|M.ulcerans_Agy99 IWERDPQTCAQAAAELG------GLGIATDVRSGDQVDAALQRTQAELGA
MMAR_4756|M.marinum_M IWERDPQTCAQAAAELG------GLGIATDVRSGDQVDAALQRTQAELGE
MAV_0894|M.avium_104 IWERDAQTCTRAAESIG------GLGIVTDVRDSGQVDTALQRTITELGT
Mflv_2424|M.gilvum_PYR-GCK IWERDPDTCAAAAAAIG------GLGLEVDVRDAAAVDTALDRTERELGT
Mvan_4228|M.vanbaalenii_PYR-1 IWERDPQTCGEAAASVG------ALGLPTDVRDAEAVQAALERTERELGT
MSMEG_4850|M.smegmatis_MC2_155 IWERDPETCEAAARAVG------GVGIVTDVRDADQVDAALAQTTSELGT
TH_3505|M.thermoresistible__bu IWERDPDSCARTAEEIG------ALGIVTDVRDSAAVSAALRQTTEQLGS
MAB_0833|M.abscessus_ATCC_1997 VASRKPEACTEAVERLRSLGA-RALGVPTHTGDIHSLEELVRATAEEFGG
MLBr_01807|M.leprae_Br4923 VTHR-----ASVVPDWF-------FGVECDVTDNDAIGAAFKAVEEHQGP
: : .. : .. . : . . . *
Mb3589c|M.bovis_AF2122/97 LDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAP
Rv3559c|M.tuberculosis_H37Rv LDVLVNNAGLGGQTPVADMTDDEWDRVLDVSLTSVFRATRAALRYFRDAP
MUL_0327|M.ulcerans_Agy99 VTILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAG
MMAR_4756|M.marinum_M VTILVNNVGGVFWSPLLQTSEKGWDALYRSNLGHVLLCTQRVARRLVAAE
MAV_0894|M.avium_104 PTILVNNAGGVFSSPLLETSENGWDALYRANLRHVLLCTQRIARQLVSVG
Mflv_2424|M.gilvum_PYR-GCK VSILVNNAGGTFNSPLLDTSENGWDALYRSNLRHVLLCTQRVARRLVAAE
Mvan_4228|M.vanbaalenii_PYR-1 VSILVNNAGGTFNSPLLETSENGWDALYRSNLRHVLLCTQRVARRLVEVG
MSMEG_4850|M.smegmatis_MC2_155 VSILVNNAGGVFASPLLETTENGWDALYKANLRHVLLCTQRVARDMVAAE
TH_3505|M.thermoresistible__bu PTILVNNAGGTFSSPLLETSENGWDALYRANLRHVLLCTQQVGRQLVAAG
MAB_0833|M.abscessus_ATCC_1997 IDIVVNNAANALTEPVGAFTVDGWDKSFGVNLRGPVFLVQAALPHLVAS-
MLBr_01807|M.leprae_Br4923 VEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQR
::* *.. : : . :: .* . .: :
Mb3589c|M.bovis_AF2122/97 HGGVIVNNASVLGWRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINA
Rv3559c|M.tuberculosis_H37Rv HGGVIVNNASVLGWRAQHSQSHYAAAKAGVMALTRCSAIEAAEYGVRINA
MUL_0327|M.ulcerans_Agy99 LPGSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTTALELAHHGIRVNA
MMAR_4756|M.marinum_M LPGSIMAITSIEGVRAAPGYAAYAAAKAGVVNYTKTAALELAHHGIRVNA
MAV_0894|M.avium_104 AGGSIISLTSIEGVRAAPGYAAYAAAKAGVINYTKTAALELAPHGIRVNA
Mflv_2424|M.gilvum_PYR-GCK QTGSVINVTSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPYGIRVNG
Mvan_4228|M.vanbaalenii_PYR-1 QPGSVINITSIEGSRAAPGYAAYAAAKAGVVNYTKTASFELAPHRIRVNA
MSMEG_4850|M.smegmatis_MC2_155 MPGSIINLTSIEGVRAAPRYAAYSAAKAGVINYTLTAAFELAPYGIRVNA
TH_3505|M.thermoresistible__bu QPGSIVNITSIEGARAAPGYAAYAAAKAGVINYTRTAAFELAPHRIRVNA
MAB_0833|M.abscessus_ATCC_1997 PHAAVLNVVSVGAFMFGQGVSMYSAAKAALVSYTRSAAAELASRGVRVNA
MLBr_01807|M.leprae_Br4923 FGRYIFMG-SVVGLSGVPGQANYAASKSGLIGMARSLARELGSRSITANV
:. *: . : *:*:*:.:: : : * . : *
Mb3589c|M.bovis_AF2122/97 VSPSIARHKFLDKTASAELLDRLVAGEAFGRAAEPWEVAATIAFLASDYS
Rv3559c|M.tuberculosis_H37Rv VSPSIARHKFLDKTASAELLDRLAAGEAFGRAAEPWEVAATIAFLASDYS
MUL_0327|M.ulcerans_Agy99 IAPDITMTEGLAQLGGAAALERIGSLVPLGRPGDVDEIASVAVFLASDMA
MMAR_4756|M.marinum_M IAPDITMTEGLAQLGGAAALERIGSLVPLGRPGDIDEIASVAVFLASDMA
MAV_0894|M.avium_104 IAPDITLTEGLQQLGGEAATTAMGNIVPLGRPGHVDEIASAAVFLASDMS
Mflv_2424|M.gilvum_PYR-GCK LAPDLTMTEGLQKLAFGELSGTVARMVPMRRAGHVDEMASAAVFLASDMA
Mvan_4228|M.vanbaalenii_PYR-1 LAPDLTMTEGLQKLAFGDLSGTMADMVPMRRVGHVDEMASAAVFLASDMA
MSMEG_4850|M.smegmatis_MC2_155 LAPDLTVTDGLLALSGGRQPG--GDAIPMKRPGHVDEMAGAAVFLASGMS
TH_3505|M.thermoresistible__bu IAPDIAVTEGLQRMSPDGIPPEVGHAIPLGRPGHVDEIAGAAVFLASEMS
MAB_0833|M.abscessus_ATCC_1997 LAPGAIDTD-MVRKTPPAEVERMANTNHLKRLGLPDEMVGTALLLTSDAG
MLBr_01807|M.leprae_Br4923 VAPGFIDTEMTRAMDS-KYQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
::*. . : * . *:... :*:* .
Mb3589c|M.bovis_AF2122/97 SYLTGEVISVSCQHP----------------------
Rv3559c|M.tuberculosis_H37Rv SYLTGEVISVSCQHP----------------------
MUL_0327|M.ulcerans_Agy99 RYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MMAR_4756|M.marinum_M RYVTGQTIHVDGGTHAAAGWYRDPQTGEYRLGPG---
MAV_0894|M.avium_104 GYLTGQTLHVDGGTQASSGWYHDPRTGDYRLGPAG--
Mflv_2424|M.gilvum_PYR-GCK SYITGQTIHVDGGTEAAGGWYFHPDNGAPTLGPA---
Mvan_4228|M.vanbaalenii_PYR-1 AYITGQTIHVDGGTAAAGGWYFHPETGVPTLGPA---
MSMEG_4850|M.smegmatis_MC2_155 SYITGQTLHVDGGTQAAGGWYHHPQTGAPTLGPG---
TH_3505|M.thermoresistible__bu SYITGQTLHVDGGTQAAGGWYHHPRTGAPTLGPGPVR
MAB_0833|M.abscessus_ATCC_1997 SYITGQTIIADGGLVAR--------------------
MLBr_01807|M.leprae_Br4923 GYISGAVIPVDGGLGMGH-------------------
*::* .: ..