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MFNSLQGRSAIVTGGSKGIGRGIAETFARAGVNVVITGRTQADIDGTVAGLAGLPGTVTGVAADVTSPED CRRVVATATERNGGLDIVCANAGIFPSGRLQDLTPEDIEQVLGVNFKGTVYIVQAALDALTASGHGRVII TSSITGPITGFPGWSHYGASKAAQMGFLRTAAIELAPKKITVNAVLPGNIITEGLVEMGQTYMDQMAASV PAGKLGEVADIGNAALFFATDEASYITGQSLVVDGGQILPESPEALADL
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_5573 | - | - | 100% (259) | short chain dehydrogenase |
| M. vanbaalenii PYR-1 | Mvan_1975 | fabG | 2e-36 | 36.44% (247) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_1616 | - | 3e-32 | 35.74% (249) | short-chain dehydrogenase/reductase SDR |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1385 | fabG | 5e-37 | 35.34% (249) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. gilvum PYR-GCK | Mflv_1235 | - | 1e-133 | 91.89% (259) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1350 | fabG | 5e-37 | 35.34% (249) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-32 | 32.22% (239) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 4e-89 | 62.45% (253) | short chain dehydrogenase |
| M. marinum M | MMAR_0587 | - | 3e-39 | 39.27% (247) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_1572 | - | 1e-37 | 36.33% (245) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0269 | - | 1e-119 | 81.08% (259) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3693 | - | 1e-35 | 35.10% (245) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3898 | fabG | 8e-36 | 36.51% (241) | 3-ketoacyl-(acyl-carrier-protein) reductase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1385|M.bovis_AF2122/97 ------------MASLLNAR--------TAVITGGAQGLGLAIGQRFVAE
Rv1350|M.tuberculosis_H37Rv ------------MASLLNAR--------TAVITGGAQGLGLAIGQRFVAE
MUL_3898|M.ulcerans_Agy99 ------------MCGAHRDRG-----YVYPVVTGGAQGLGLAIAERFVSE
MAV_1572|M.avium_104 -------------MSLLSGQ--------TAVITGGAQGLGFAIAERFVAE
TH_3693|M.thermoresistible__bu -------------VSLLAGQ--------TAVVTGGARGLGYAIAERFIAE
MLBr_01807|M.leprae_Br4923 ------MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVAD
Mvan_5573|M.vanbaalenii_PYR-1 ------------MFNSLQGR--------SAIVTGGSKGIGRGIAETFARA
Mflv_1235|M.gilvum_PYR-GCK ------------MFTSLQGR--------SAAVTGGSKGIGRGIAETFARA
MSMEG_0269|M.smegmatis_MC2_155 ------------MFTSLEGR--------SAIVTGGSKGIGRGIAETFANA
MAB_0952|M.abscessus_ATCC_1997 MVVESAEPAERKVMFDLSAR--------SVLVTGGTKGIGRGIATVFARA
MMAR_0587|M.marinum_M -------------MGQLEGK--------TALVTGGNSGIGLAAAQRLAAE
: :*** *:* . . :
Mb1385|M.bovis_AF2122/97 GARVVLGDVNLEATEVAAKRLGGD--DVALAVRCDVTQADDVDILIRTAV
Rv1350|M.tuberculosis_H37Rv GARVVLGDVNLEATEVAAKRLGGD--DVALAVRCDVTQADDVDILIRTAV
MUL_3898|M.ulcerans_Agy99 GARVVLGDVNLEATEAAAKQLGGG--EVAVAVRCDVTKADEVETLLQAAL
MAV_1572|M.avium_104 GARVVLGDVNLEATQTAAKQLGGD--QVALAVRCDVTKSSEVETLIQTAV
TH_3693|M.thermoresistible__bu GARVVIGDIDESATRAAADSLGGA--DVAVGMRCDVTRSDEVEALVGAAV
MLBr_01807|M.leprae_Br4923 GHRVAVTHR---ASVVPDWFFG---------VECDVTDNDAIGAAFKAVE
Mvan_5573|M.vanbaalenii_PYR-1 GVNVVITGRTQADIDGTVAGLAGL-PGTVTGVAADVTSPEDCRRVVATAT
Mflv_1235|M.gilvum_PYR-GCK GINVVITARTQDDIDATVADLAGL-AGTVTGVAADVTSPEDCRRVVETAI
MSMEG_0269|M.smegmatis_MC2_155 GVDVVITGRNQDDLDRTVADLSGT-RGKVTAVRADVTDPEDARRTVAETV
MAB_0952|M.abscessus_ATCC_1997 GANVAVAARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVV
MMAR_0587|M.marinum_M GAHVFLTGRNQATIDAAVASIGSR----AHGIRADVSNIEDLARVADAIA
* * : :. : **:
Mb1385|M.bovis_AF2122/97 ERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAI
Rv1350|M.tuberculosis_H37Rv ERFGGLDVMVNNAGITRDATMRTMTEEQFDQVIAVHLKGTWNGTRLAAAI
MUL_3898|M.ulcerans_Agy99 ERFGGLDIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAI
MAV_1572|M.avium_104 ERFGGLDIMVNNAGITRDATMRKMTEEQFDQVIAVHLKGTWNGTRLAAAI
TH_3693|M.thermoresistible__bu KRFGSLDVMVNNAGITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAI
MLBr_01807|M.leprae_Br4923 EHQGPVEVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRN
Mvan_5573|M.vanbaalenii_PYR-1 ERNGGLDIVCANAGIFPSGRLQDLTPEDIEQVLGVNFKGTVYIVQAALDA
Mflv_1235|M.gilvum_PYR-GCK ERHGGLDIVCPNAGIFPSGRIADLTPDDIEQVLGVNFKGTVYIVQAALDA
MSMEG_0269|M.smegmatis_MC2_155 SRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQA
MAB_0952|M.abscessus_ATCC_1997 DAFGALDVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAP
MMAR_0587|M.marinum_M AAGRGLDVLFANAGGGEFVLLGDITIEHFTNGFMTNVAGTLFTVQTMLPL
:::: *** : :: :.: : : .:. *. :
Mb1385|M.bovis_AF2122/97 MRERKRGAIVNMSSVSG-KVGMVGQTNYSAAKAGIVGMTKAAAKELAHLG
Rv1350|M.tuberculosis_H37Rv MRERKRGAIVNMSSVSG-KVGMVGQTNYSAAKAGIVGMTKAAAKELAHLG
MUL_3898|M.ulcerans_Agy99 MRENKRGAIVNMSSVSG-KVGMVGQTNYSAAKAGIVGMTKAAAKELAHVG
MAV_1572|M.avium_104 MRENKRGAIINMSSVSG-KVGMVGQTNYSAAKAGIVGMTKAAAKELAYLG
TH_3693|M.thermoresistible__bu MREQKRGAIVNMSSISG-KVGMVGQTNYSAAKAGIVGMTKAASKELAYLG
MLBr_01807|M.leprae_Br4923 MIKQRFGRYIFMGSVVG-LSGVPGQANYAASKSGLIGMARSLARELGSRS
Mvan_5573|M.vanbaalenii_PYR-1 LTASGHGRVIITSSITGPITGFPGWSHYGASKAAQMGFLRTAAIELAPKK
Mflv_1235|M.gilvum_PYR-GCK LTASGHGRVIITSSITGPITGFPGWSHYGASKAAQLGFLRTAAIELAPKK
MSMEG_0269|M.smegmatis_MC2_155 LTASGHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKK
MAB_0952|M.abscessus_ATCC_1997 LTASGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRG
MMAR_0587|M.marinum_M LNS---GASIVLTGSTAAYNGSPAFSVYAATKAAIRSFGRTWAAELVSRN
: * : . . * . : *.*:*:. .: :: : **
Mb1385|M.bovis_AF2122/97 IRVNAIAPGLIRSAMTEAMP-----QRIWDQKLAEVPMGRAGEPSEVASV
Rv1350|M.tuberculosis_H37Rv IRVNAIAPGLIRSAMTEAMP-----QRIWDQKLAEVPMGRAGEPSEVASV
MUL_3898|M.ulcerans_Agy99 VRVNAIAPGLIRSAMTEAMP-----QRIWDQKLAEVPMGRAGEPSEVASV
MAV_1572|M.avium_104 VRVNAIAPGLIRSAMTEAMP-----QRIWDSKVAEVPMGRAGEPSEVASV
TH_3693|M.thermoresistible__bu VRVNAIQPGLIRSAMTEAMP-----QRIWDEKLAEIPMGRAGEPEEVAKV
MLBr_01807|M.leprae_Br4923 ITANVVAPGFIDTEMTRAMD-----SKYQEAALQAIPLGRIGAVEEIAGA
Mvan_5573|M.vanbaalenii_PYR-1 ITVNAVLPGNIITEGLVEMG-----QTYMDQMAASVPAGKLGEVADIGNA
Mflv_1235|M.gilvum_PYR-GCK ITVNAVLPGNILTEGLVEMG-----QSYIDQMAAAVPAGKLGEVADIGNA
MSMEG_0269|M.smegmatis_MC2_155 ITINAVLPGNIMTEGLDEMG-----QDYLDQMASAIPAGRLGSVADIGNA
MAB_0952|M.abscessus_ATCC_1997 VTVNAILPGNILTEGLVDMG-----EEYISGMARSIPMGMLGSPVDIGHL
MMAR_0587|M.marinum_M IRVNTVVPGPVETPGLKGLAPEGQEQQLLEGEAAKVPMGRLGKPAEIAAA
: *.: ** : : : . . :* * * ::.
Mb1385|M.bovis_AF2122/97 AVFLASDLSSYMTGTVLDVTGGRFI----------
Rv1350|M.tuberculosis_H37Rv AVFLASDLSSYMTGTVLDVTGGRFI----------
MUL_3898|M.ulcerans_Agy99 ALFLACDLSSYMTGTVLDVTGGRFI----------
MAV_1572|M.avium_104 ALFLASDMSSYMTGTVMEITGGRHL----------
TH_3693|M.thermoresistible__bu ALFLASDLSSYMTGTVLEVTGGRHL----------
MLBr_01807|M.leprae_Br4923 VSFLASEDAGYISGAVIPVDGGLGMGH--------
Mvan_5573|M.vanbaalenii_PYR-1 ALFFATDEASYITGQSLVVDGGQILPESPEALADL
Mflv_1235|M.gilvum_PYR-GCK ALFFATDEAAYITGQSLVVDGGQILPESPEALADL
MSMEG_0269|M.smegmatis_MC2_155 ALFFATDEAAYVTGQTLVVDGGQVLPESHLAIAEL
MAB_0952|M.abscessus_ATCC_1997 AAFLATDEAGYITGQAIVVDGGQVLPESPDAVNP-
MMAR_0587|M.marinum_M VLFLASDQSSFMTGSEMFVDGG------TEQL---
. *:* : :.:::* : : **