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LVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAVAARSPRELSSVTAELGELGAGN VIGVRLDVSDPGSCADAARTVVDAFGALDVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACL APLTASGRGRVILTSSITGPVTGYPGWSHYGASKAAQLGFMRTAAIELAPRGVTVNAILPGNILTEGLVD MGEEYISGMARSIPMGMLGSPVDIGHLAAFLATDEAGYITGQAIVVDGGQVLPESPDAVNP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0952 | - | - | 100% (271) | short chain dehydrogenase |
| M. abscessus ATCC 19977 | MAB_0833 | - | 8e-38 | 38.31% (248) | Short-chain dehydrogenase/reductase |
| M. abscessus ATCC 19977 | MAB_2723c | - | 3e-34 | 34.17% (240) | 3-oxoacyl- |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 8e-39 | 37.30% (252) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1235 | - | 6e-90 | 62.85% (253) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1928c | - | 8e-39 | 37.30% (252) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 1e-34 | 35.29% (255) | 3-oxoacyl- |
| M. marinum M | MMAR_2849 | - | 1e-37 | 36.11% (252) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2775 | - | 1e-39 | 35.71% (252) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0779 | - | 1e-104 | 73.05% (256) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_2589 | - | 1e-36 | 36.18% (246) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3898 | fabG | 3e-34 | 35.68% (241) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5573 | - | 5e-89 | 62.45% (253) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1963c|M.bovis_AF2122/97 ---------MSVLDLFD-LHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv ---------MSVLDLFD-LHGKRALITGASTGIGKRVALAYVEAGAQVAI
MMAR_2849|M.marinum_M ---------MSVLDLFD-LSGKRALITGASTGIGKKVALAYAEAGAQVAV
MAV_2775|M.avium_104 -----------MLDLFD-LRGRRALVTGASTGIGKQVAQAYLQAGARVAI
MAB_0952|M.abscessus_ATCC_1997 -MVVESAEPAERKVMFD-LSARSVLVTGGTKGIGRGIATVFARAGANVAV
MSMEG_0779|M.smegmatis_MC2_155 --------------MFD-LQGRSVVVTGGTKGIGRGIATVFARAGANVAV
Mflv_1235|M.gilvum_PYR-GCK --------------MFTSLQGRSAAVTGGSKGIGRGIAETFARAGINVVI
Mvan_5573|M.vanbaalenii_PYR-1 --------------MFNSLQGRSAIVTGGSKGIGRGIAETFARAGVNVVI
TH_2589|M.thermoresistible__bu ------VDRQTFDKLFD-MTGRTVVVTGGTRGIGLALAEGYVLAGARVVV
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
MUL_3898|M.ulcerans_Agy99 ------MCGAHRDRG-----YVYPVVTGGAQGLGLAIAERFVSEGARVVL
:**. *:* :* * .*.:
Mb1963c|M.bovis_AF2122/97 AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Rv1928c|M.tuberculosis_H37Rv AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
MMAR_2849|M.marinum_M AARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGELGGI
MAV_2775|M.avium_104 AARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAELGGI
MAB_0952|M.abscessus_ATCC_1997 AARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGAL
MSMEG_0779|M.smegmatis_MC2_155 AGRSTADIDACVADLDQLGSGKVIGVQTDVSDRAQCDALAGRAVEEFGGI
Mflv_1235|M.gilvum_PYR-GCK TARTQDDIDATVADLAGL-AGTVTGVAADVTSPEDCRRVVETAIERHGGL
Mvan_5573|M.vanbaalenii_PYR-1 TGRTQADIDGTVAGLAGL-PGTVTGVAADVTSPEDCRRVVATATERNGGL
TH_2589|M.thermoresistible__bu ASRKSDACERAAAHLRAL-GGDAIGVPTHLGDIDACEALVRRTVDEFGGI
MLBr_01807|M.leprae_Br4923 THR---ASVVPDWFFG---------VECDVTDNDAIGAAFKAVEEHQGPV
MUL_3898|M.ulcerans_Agy99 GDVNLEATEAAAKQLGGG--EVAVAVRCDVTKADEVETLLQAALERFGGL
: : .: . * :
Mb1963c|M.bovis_AF2122/97 DIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQ
Rv1928c|M.tuberculosis_H37Rv DIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQ
MMAR_2849|M.marinum_M DIAVCNAGIVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMVDQGL
MAV_2775|M.avium_104 DIAVCNAGIISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVRQGR
MAB_0952|M.abscessus_ATCC_1997 DVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTASGR
MSMEG_0779|M.smegmatis_MC2_155 DVVCANAGVFPDAPLATMTPEQLNGIFAVNVNGTFYAVQACLDALIASGS
Mflv_1235|M.gilvum_PYR-GCK DIVCPNAGIFPSGRIADLTPDDIEQVLGVNFKGTVYIVQAALDALTASGH
Mvan_5573|M.vanbaalenii_PYR-1 DIVCANAGIFPSGRLQDLTPEDIEQVLGVNFKGTVYIVQAALDALTASGH
TH_2589|M.thermoresistible__bu DVLVNNAANALTQPLGELTVDAWTKSFEVNLRGPVFLVQAALPHLKTSPH
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
MUL_3898|M.ulcerans_Agy99 DIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENKR
:: **. : :. .:. * : . : .
Mb1963c|M.bovis_AF2122/97 GGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVN
Rv1928c|M.tuberculosis_H37Rv GGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVN
MMAR_2849|M.marinum_M GGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQIRVN
MAV_2775|M.avium_104 GGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHDIRVN
MAB_0952|M.abscessus_ATCC_1997 G-RVILTSSITGPVTGYPG-WSHYGASKAAQLGFMRTAAIELAPRGVTVN
MSMEG_0779|M.smegmatis_MC2_155 G-RVVLTSSITGPITGYPG-WSHYGATKAAQLGFMRTAAIELAPHKITVN
Mflv_1235|M.gilvum_PYR-GCK G-RVIITSSITGPITGFPG-WSHYGASKAAQLGFLRTAAIELAPKKITVN
Mvan_5573|M.vanbaalenii_PYR-1 G-RVIITSSITGPITGFPG-WSHYGASKAAQMGFLRTAAIELAPKKITVN
TH_2589|M.thermoresistible__bu A-AVLNMVSVG-AFLFSPG-TAMYSAGKAALMSFTRSMAAQFAPLGIRVN
MLBr_01807|M.leprae_Br4923 G-RYIFMGSVVGLSGVPGQ--ANYAASKSGLIGMARSLARELGSRSITAN
MUL_3898|M.ulcerans_Agy99 G-AIVNMSSVSGKVGMVGQ--TNYSAAKAGIVGMTKAAAKELAHVGVRVN
. : *: * : *:. : : :: * ::. : .*
Mb1963c|M.bovis_AF2122/97 SVSPGYILTE-LVEPYTEYQPLWEPKIPLGRLGRPEELAGLYLYLASEAS
Rv1928c|M.tuberculosis_H37Rv SVSPGYILTE-LVEPYTEYQPLWEPKIPLGRLGRPEELAGLYLYLASEAS
MMAR_2849|M.marinum_M SVSPGYIRTE-LVEPLADYHALWEPKIPLGRMGRPEELTGLYLYLASAAS
MAV_2775|M.avium_104 SVSPGYIRTE-LVEPLHEYHRQWQPKIPLGRMGRPDELAGIYLYLASAAS
MAB_0952|M.abscessus_ATCC_1997 AILPGNILTEGLVDMGEEYISGMARSIPMGMLGSPVDIGHLAAFLATDEA
MSMEG_0779|M.smegmatis_MC2_155 AIMPGNIMTEGLLENGEEYIASMARSIPAGALGTPEDIGHLAAFLATKEA
Mflv_1235|M.gilvum_PYR-GCK AVLPGNILTEGLVEMGQSYIDQMAAAVPAGKLGEVADIGNAALFFATDEA
Mvan_5573|M.vanbaalenii_PYR-1 AVLPGNIITEGLVEMGQTYMDQMAASVPAGKLGEVADIGNAALFFATDEA
TH_2589|M.thermoresistible__bu ALAPGPVDTDMMRNNPQEVVDMMAGATLMKRLATPDEMVGAALLLTSDAG
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
MUL_3898|M.ulcerans_Agy99 AIAPGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLS
: ** : : . :: :: .
Mb1963c|M.bovis_AF2122/97 SYMTGSDIVIDGGYTCP---------
Rv1928c|M.tuberculosis_H37Rv SYMTGSDIVIDGGYTCP---------
MMAR_2849|M.marinum_M SYMTGSDIVIDGGYTCP---------
MAV_2775|M.avium_104 SYMTGSDIVIDGGYSCP---------
MAB_0952|M.abscessus_ATCC_1997 GYITGQAIVVDGGQVLPESPDAVNP-
MSMEG_0779|M.smegmatis_MC2_155 GYITGQAIAVDGGQVLPESLDAIAT-
Mflv_1235|M.gilvum_PYR-GCK AYITGQSLVVDGGQILPESPEALADL
Mvan_5573|M.vanbaalenii_PYR-1 SYITGQSLVVDGGQILPESPEALADL
TH_2589|M.thermoresistible__bu SYITGTVLIADGGGTPR---------
MLBr_01807|M.leprae_Br4923 GYISGAVIPVDGGLGMGH--------
MUL_3898|M.ulcerans_Agy99 SYMTGTVLDVTGGRFI----------
.*::* : **