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FTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRADVTDPEDA RRTVAETVSRHGGLDIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGHGRVVVT SSITGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNIMTEGLDEMGQDYLDQMASAIP AGRLGSVADIGNAALFFATDEAAYVTGQTLVVDGGQVLPESHLAIAEL*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0269 | - | - | 100% (259) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_0779 | - | 1e-84 | 60.63% (254) | short chain dehydrogenase |
| M. smegmatis MC2 155 | MSMEG_2206 | fabG | 1e-38 | 37.45% (243) | 3-ketoacyl-(acyl-carrier-protein) reductase |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1963c | - | 2e-38 | 35.08% (248) | short chain dehydrogenase |
| M. gilvum PYR-GCK | Mflv_1235 | - | 1e-122 | 81.85% (259) | short chain dehydrogenase |
| M. tuberculosis H37Rv | Rv1928c | - | 2e-38 | 35.08% (248) | short chain dehydrogenase |
| M. leprae Br4923 | MLBr_01807 | fabG1 | 4e-31 | 33.75% (240) | 3-oxoacyl- |
| M. abscessus ATCC 19977 | MAB_0952 | - | 1e-85 | 61.72% (256) | short chain dehydrogenase |
| M. marinum M | MMAR_2849 | - | 1e-38 | 34.27% (248) | short-chain type dehydrogenase/reductase |
| M. avium 104 | MAV_2775 | - | 2e-38 | 36.14% (249) | short chain dehydrogenase |
| M. thermoresistible (build 8) | TH_3693 | - | 2e-36 | 35.51% (245) | PUTATIVE short-chain dehydrogenase/reductase SDR |
| M. ulcerans Agy99 | MUL_3898 | fabG | 8e-36 | 34.73% (239) | 3-ketoacyl-(acyl-carrier-protein) reductase |
| M. vanbaalenii PYR-1 | Mvan_5573 | - | 1e-120 | 81.08% (259) | short chain dehydrogenase |
CLUSTAL 2.0.9 multiple sequence alignment
TH_3693|M.thermoresistible__bu -------VSLLAGQT--------AVVTGGARGLGYAIAERFIAEGARVVI
MUL_3898|M.ulcerans_Agy99 ----MCGAHRDRGYVY-------PVVTGGAQGLGLAIAERFVSEGARVVL
MLBr_01807|M.leprae_Br4923 MTDAAAKVSAAPGRGKPAFVSRSILVTGGNRGIGLAVARRLVADGHRVAV
Mflv_1235|M.gilvum_PYR-GCK --------------MFTSLQGRSAAVTGGSKGIGRGIAETFARAGINVVI
Mvan_5573|M.vanbaalenii_PYR-1 --------------MFNSLQGRSAIVTGGSKGIGRGIAETFARAGVNVVI
MSMEG_0269|M.smegmatis_MC2_155 --------------MFTSLEGRSAIVTGGSKGIGRGIAETFANAGVDVVI
MAB_0952|M.abscessus_ATCC_1997 --MVVESAEPAERKVMFDLSARSVLVTGGTKGIGRGIATVFARAGANVAV
Mb1963c|M.bovis_AF2122/97 ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
Rv1928c|M.tuberculosis_H37Rv ----------MSVLDLFDLHGKRALITGASTGIGKRVALAYVEAGAQVAI
MMAR_2849|M.marinum_M ----------MSVLDLFDLSGKRALITGASTGIGKKVALAYAEAGAQVAV
MAV_2775|M.avium_104 ------------MLDLFDLRGRRALVTGASTGIGKQVAQAYLQAGARVAI
:**. *:* :* * *.:
TH_3693|M.thermoresistible__bu GDIDESATRAAADSLGGA--DVAVGMRCDVTRSDEVEALVGAAVKRFGSL
MUL_3898|M.ulcerans_Agy99 GDVNLEATEAAAKQLGGG--EVAVAVRCDVTKADEVETLLQAALERFGGL
MLBr_01807|M.leprae_Br4923 -------THRASVVP-----DWFFGVECDVTDNDAIGAAFKAVEEHQGPV
Mflv_1235|M.gilvum_PYR-GCK TARTQDDIDATVADLAGL-AGTVTGVAADVTSPEDCRRVVETAIERHGGL
Mvan_5573|M.vanbaalenii_PYR-1 TGRTQADIDGTVAGLAGL-PGTVTGVAADVTSPEDCRRVVATATERNGGL
MSMEG_0269|M.smegmatis_MC2_155 TGRNQDDLDRTVADLSGT-RGKVTAVRADVTDPEDARRTVAETVSRHGGL
MAB_0952|M.abscessus_ATCC_1997 AARSPRELSSVTAELGELGAGNVIGVRLDVSDPGSCADAARTVVDAFGAL
Mb1963c|M.bovis_AF2122/97 AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
Rv1928c|M.tuberculosis_H37Rv AARHLDALEKLADEIGTSG-GKVVPVCCDVSQHQQVTSMLDQVTAELGGI
MMAR_2849|M.marinum_M AARHSDALQVVADEIAGVG-GKALPIRCDVTQPDQVRGMLDQMTGELGGI
MAV_2775|M.avium_104 AARDFEALQRTADELTAGGTGGVVAIRCDVTQPDEVSGMVDRMIAELGGI
: **: * :
TH_3693|M.thermoresistible__bu DVMVNNAGITRDATMRKMTEQQFDEVIAVHLKGTWNGLRAAAAIMREQKR
MUL_3898|M.ulcerans_Agy99 DIMVNNAGITRDATMRKMTEEQFDQVIDVHLKGTWNGIRLAAAIMRENKR
MLBr_01807|M.leprae_Br4923 EVLVANAGITSDMLIMRMSEEQFQKVIDVNLTGVFRVAKLASRNMIKQRF
Mflv_1235|M.gilvum_PYR-GCK DIVCPNAGIFPSGRIADLTPDDIEQVLGVNFKGTVYIVQAALDALTASGH
Mvan_5573|M.vanbaalenii_PYR-1 DIVCANAGIFPSGRLQDLTPEDIEQVLGVNFKGTVYIVQAALDALTASGH
MSMEG_0269|M.smegmatis_MC2_155 DIVCANAGIFPSGRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTASGH
MAB_0952|M.abscessus_ATCC_1997 DVVCANAGIFPEARLDTMTPEQLSEVLDVNVKGTVYTVQACLAPLTASGR
Mb1963c|M.bovis_AF2122/97 DIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQ
Rv1928c|M.tuberculosis_H37Rv DIAVCNAGIITVTPMLDMPLEEFQRLQNTNVTGVFLTAQAAAKAMVKQGQ
MMAR_2849|M.marinum_M DIAVCNAGIVSVQAMLDMPLEEFQRIQDTNVTGVFLTAQAAARAMVDQGL
MAV_2775|M.avium_104 DIAVCNAGIISVSPMLEMPAAEFQRIQDTNVTGVFLTAQAAARAMVRQGR
:: **** : :. ::..: .:..*. : . : .
TH_3693|M.thermoresistible__bu G-AIVNMSSISG-KVGMVG-QTNYSAAKAGIVGMTKAASKELAYLGVRVN
MUL_3898|M.ulcerans_Agy99 G-AIVNMSSVSG-KVGMVG-QTNYSAAKAGIVGMTKAAAKELAHVGVRVN
MLBr_01807|M.leprae_Br4923 G-RYIFMGSVVG-LSGVPG-QANYAASKSGLIGMARSLARELGSRSITAN
Mflv_1235|M.gilvum_PYR-GCK G-RVIITSSITGPITGFPG-WSHYGASKAAQLGFLRTAAIELAPKKITVN
Mvan_5573|M.vanbaalenii_PYR-1 G-RVIITSSITGPITGFPG-WSHYGASKAAQMGFLRTAAIELAPKKITVN
MSMEG_0269|M.smegmatis_MC2_155 G-RVVVTSSITGPITGYPG-WSHYGASKAAQLGFLRTAAMELAPKKITIN
MAB_0952|M.abscessus_ATCC_1997 G-RVILTSSITGPVTGYPG-WSHYGASKAAQLGFMRTAAIELAPRGVTVN
Mb1963c|M.bovis_AF2122/97 GGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVN
Rv1928c|M.tuberculosis_H37Rv GGVIINTASMSGHIINVPQQVSHYCASKAAVIHLTKAMAVELAPHKIRVN
MMAR_2849|M.marinum_M GGTIITTASMSGHIINIPQQVSHYCTSKAAVVHLTKAMAVELAPHQIRVN
MAV_2775|M.avium_104 GGAIITTASMSGHIINVPQQVGHYCASKAAVIQLTKAMAVEFAPHDIRVN
* : .*: * . :* ::*:. : : :: : *:. : *
TH_3693|M.thermoresistible__bu AIQPGLIRSAMTEAMPQRIWDEKLAEIPMGRAGEPEEVAKVALFLASDLS
MUL_3898|M.ulcerans_Agy99 AIAPGLIRSAMTEAMPQRIWDQKLAEVPMGRAGEPSEVASVALFLACDLS
MLBr_01807|M.leprae_Br4923 VVAPGFIDTEMTRAMDSKYQEAALQAIPLGRIGAVEEIAGAVSFLASEDA
Mflv_1235|M.gilvum_PYR-GCK AVLPGNILTEGLVEMGQSYIDQMAAAVPAGKLGEVADIGNAALFFATDEA
Mvan_5573|M.vanbaalenii_PYR-1 AVLPGNIITEGLVEMGQTYMDQMAASVPAGKLGEVADIGNAALFFATDEA
MSMEG_0269|M.smegmatis_MC2_155 AVLPGNIMTEGLDEMGQDYLDQMASAIPAGRLGSVADIGNAALFFATDEA
MAB_0952|M.abscessus_ATCC_1997 AILPGNILTEGLVDMGEEYISGMARSIPMGMLGSPVDIGHLAAFLATDEA
Mb1963c|M.bovis_AF2122/97 SVSPGYILTE-LVEPYTEYQPLWEPKIPLGRLGRPEELAGLYLYLASEAS
Rv1928c|M.tuberculosis_H37Rv SVSPGYILTE-LVEPYTEYQPLWEPKIPLGRLGRPEELAGLYLYLASEAS
MMAR_2849|M.marinum_M SVSPGYIRTE-LVEPLADYHALWEPKIPLGRMGRPEELTGLYLYLASAAS
MAV_2775|M.avium_104 SVSPGYIRTE-LVEPLHEYHRQWQPKIPLGRMGRPDELAGIYLYLASAAS
: ** * : :* * * :: ::* :
TH_3693|M.thermoresistible__bu SYMTGTVLEVTGGRHL----------
MUL_3898|M.ulcerans_Agy99 SYMTGTVLDVTGGRFI----------
MLBr_01807|M.leprae_Br4923 GYISGAVIPVDGGLGMGH--------
Mflv_1235|M.gilvum_PYR-GCK AYITGQSLVVDGGQILPESPEALADL
Mvan_5573|M.vanbaalenii_PYR-1 SYITGQSLVVDGGQILPESPEALADL
MSMEG_0269|M.smegmatis_MC2_155 AYVTGQTLVVDGGQVLPESHLAIAEL
MAB_0952|M.abscessus_ATCC_1997 GYITGQAIVVDGGQVLPESPDAVNP-
Mb1963c|M.bovis_AF2122/97 SYMTGSDIVIDGGYTCP---------
Rv1928c|M.tuberculosis_H37Rv SYMTGSDIVIDGGYTCP---------
MMAR_2849|M.marinum_M SYMTGSDIVIDGGYTCP---------
MAV_2775|M.avium_104 SYMTGSDIVIDGGYSCP---------
.*::* : : **