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VPRKRLTRAEARAQTRRRLLDAAAETFARKGYDAASVEEIAEAAGYSVGAVYSNFSSKEQLFSELRSERA ALRLDEVADALRSAQGDPGGPFAKLSRQLVEVADKNIEVAALHTEFWLHAIRNPGAMDVLAESVGQTLQS LTGIAADLLAEHNVDQSVVRPETFAVSLLALHQGLIRQRRTNPSWVPEELFGQLLSWLLAGMPKLPAH*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. smegmatis MC2 155 | MSMEG_0148 | - | - | 100% (209) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 6e-19 | 32.18% (174) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_2182 | - | 8e-10 | 30.36% (168) | transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 1e-09 | 29.12% (182) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2460 | - | 1e-18 | 32.95% (176) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 1e-09 | 29.12% (182) | transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 2e-07 | 35.37% (82) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2913 | - | 4e-17 | 30.60% (183) | TetR family regulatory protein |
| M. marinum M | MMAR_4631 | - | 6e-15 | 34.93% (146) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 2e-21 | 30.20% (202) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4015 | - | 1e-10 | 40.00% (85) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0245 | - | 1e-10 | 32.56% (129) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4193 | - | 9e-19 | 34.67% (199) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_4631|M.marinum_M --------------------MTPPANTATPARVTKRRAETRARLVDAAFR
MUL_0245|M.ulcerans_Agy99 --------------------------------------------------
Mflv_2460|M.gilvum_PYR-GCK --------------------------MVERWTRERRLEHTRSVLLDAAEE
Mvan_4193|M.vanbaalenii_PYR-1 --------------------------MAERWTRQRRVEHTRTLLLDAAEE
Mb1561|M.bovis_AF2122/97 --------------------MSRASARRRRAVSDEDKSQRRDEILAAAKI
Rv1534|M.tuberculosis_H37Rv --------------------MSRASARRRRAVSDEDKSQRRDEILAAAKI
MSMEG_0148|M.smegmatis_MC2_155 ------------------------MVPRKRLTRAEARAQTRRRLLDAAAE
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
MAB_2913|M.abscessus_ATCC_1997 -------------MYPYRFTVITTGRLLMSTGSTRRREHTRARLMQAALD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_4015|M.thermoresistible__bu -VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKE
MMAR_4631|M.marinum_M VFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MUL_0245|M.ulcerans_Agy99 MFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
Mflv_2460|M.gilvum_PYR-GCK VFAEKGFTPATLDDIARAAGYTKGAIYKHFDTKEELFLAVSDRYWRRYFD
Mvan_4193|M.vanbaalenii_PYR-1 VVARLGFGAAALEVIADAAGYTRGAIYSHFGTKEELFLAVMERQLQRFLD
Mb1561|M.bovis_AF2122/97 VFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRA
Rv1534|M.tuberculosis_H37Rv VFAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRA
MSMEG_0148|M.smegmatis_MC2_155 TFARKGYDAASVEEIAEAAGYSVGAVYSNFSSKEQLFSELRSERAALRLD
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
MAB_2913|M.abscessus_ATCC_1997 VFADRGFHGASIENICEKAGFTRGAFYSNFAGKDELFFTLFDASSEQLLT
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_4015|M.thermoresistible__bu VFARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQ
.. *: . : : ** : .* * ::: :
MMAR_4631|M.marinum_M QVGTAMASVD--DPTDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARH
MUL_0245|M.ulcerans_Agy99 QVGTAMASVG--DPTDVPGTVDRIASTLLLDR--DWLLIKTDFLMHAARH
Mflv_2460|M.gilvum_PYR-GCK NFAEVMSSASRVGADELDEIAERWR-QLSIDRGAEHAALGLEFTLYLLRN
Mvan_4193|M.vanbaalenii_PYR-1 GFTDIVESFQSLEELDVDKLAGRWR-ELTIGN-PDRAALGYEFTLFLVRN
Mb1561|M.bovis_AF2122/97 HVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALG
Rv1534|M.tuberculosis_H37Rv HVAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALG
MSMEG_0148|M.smegmatis_MC2_155 EVADALRSAQGDPGGPFAKLSRQLV--EVADKNIEVAALHTEFWLHAIRN
MAV_1611|M.avium_104 QIAIALDRSAGDTTAAAREVSRSVLDSVRDHS--DYYVLLVEYWLRAQRD
MAB_2913|M.abscessus_ATCC_1997 QLRAALDECRK-SPDPLSTFIRTIDDKGPTQR--RWYLISMEFTLYAIRE
MLBr_00815|M.leprae_Br4923 SVQQALRTTTN-----NRQRLHAAVQAFFDFIEHDGQGYRLIFENDNITE
TH_4015|M.thermoresistible__bu PVRTDAGTEPKNPYERILRANRTYLEAYRANR-----AIMIVWEQVASLN
. :
MMAR_4631|M.marinum_M PDLAQRLAAHRAQLRAAVEDRLAGSDVEL-PAAIG-SVADAARAVVAAYD
MUL_0245|M.ulcerans_Agy99 PDLAQRLAAHRAQLRAAVEDRLAGSDVEL-PAAIG-SVADAARAVVAAYD
Mflv_2460|M.gilvum_PYR-GCK PEARERVEAKRAEVVDQLAEFIVEGMSQL-GATLLIEPSTFARALVATSD
Mvan_4193|M.vanbaalenii_PYR-1 PEARARVAAQRRQTADSLAGYITSHIEKI-GGRMRVPAATLARVLIATNE
Mb1561|M.bovis_AF2122/97 GRFEEHLGGIYERFIDDIEAVVVAAQRR---GEVVEAPSRMAAYTLAALV
Rv1534|M.tuberculosis_H37Rv GRFEEHLGGIYERFIDDIEAVVVAAQRR---GEVVEAPSRMAAYTLAALV
MSMEG_0148|M.smegmatis_MC2_155 PGAMDVLAESVGQTLQSLTGIAADLLAEHNVDQSVVRPETFAVSLLALHQ
MAV_1611|M.avium_104 PQLRERLIERRRAAADQALHIVESTDTVP----GDRRLTDIAQLVVTLNL
MAB_2913|M.abscessus_ATCC_1997 PSAAVVLAEHDARLRREAAGIINELMSIA-HRELIIDTELIARLATALRE
MLBr_00815|M.leprae_Br4923 PRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARY
TH_4015|M.thermoresistible__bu EHVEQLRREYSDRFAARIERAIIRWQEAG-LADPAIDPRYAAAALSGMLS
.
MMAR_4631|M.marinum_M GVSIQLLLDGD---QDAARAWLSQLLGVVLIR------------------
MUL_0245|M.ulcerans_Agy99 GVSIQLLLDGD---QDAARAWLSQLLGVVLIR------------------
Mflv_2460|M.gilvum_PYR-GCK SVVLGSQLDA----VDLYRPMVEMYVSVIKLPD-----------------
Mvan_4193|M.vanbaalenii_PYR-1 GVTLGSHVDG----EDLFRPFLEMVLGNVEPAG-----------------
Mb1561|M.bovis_AF2122/97 GQLAHRRLNTD---DNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAAR
Rv1534|M.tuberculosis_H37Rv GQLAHRRLNTD---DNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAAR
MSMEG_0148|M.smegmatis_MC2_155 GLIRQRRTNPSWVPEELFGQLLSWLLAGMPKLPAH---------------
MAV_1611|M.avium_104 GVAMEEVLRPGTINPDLLAQLITALLESIPV-------------------
MAB_2913|M.abscessus_ATCC_1997 GVAAQFYVEPELAETRMLERLAFPAMLRAFSQPVGAD-------------
MLBr_00815|M.leprae_Br4923 WLDTNRPISKS----DAVEGTVQFAWGGLSHVPLTRL-------------
TH_4015|M.thermoresistible__bu NFAYRWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA-------
MMAR_4631|M.marinum_M -
MUL_0245|M.ulcerans_Agy99 -
Mflv_2460|M.gilvum_PYR-GCK -
Mvan_4193|M.vanbaalenii_PYR-1 -
Mb1561|M.bovis_AF2122/97 T
Rv1534|M.tuberculosis_H37Rv T
MSMEG_0148|M.smegmatis_MC2_155 -
MAV_1611|M.avium_104 -
MAB_2913|M.abscessus_ATCC_1997 -
MLBr_00815|M.leprae_Br4923 -
TH_4015|M.thermoresistible__bu -