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VAERWTRQRRVEHTRTLLLDAAEEVVARLGFGAAALEVIADAAGYTRGAIYSHFGTKEELFLAVMERQLQ RFLDGFTDIVESFQSLEELDVDKLAGRWRELTIGNPDRAALGYEFTLFLVRNPEARARVAAQRRQTADSL AGYITSHIEKIGGRMRVPAATLARVLIATNEGVTLGSHVDGEDLFRPFLEMVLGNVEPAG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. vanbaalenii PYR-1 | Mvan_4193 | - | - | 100% (200) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 2e-68 | 61.42% (197) | TetR family transcriptional regulator |
| M. vanbaalenii PYR-1 | Mvan_4194 | - | 2e-51 | 50.52% (192) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0310 | - | 5e-13 | 29.61% (179) | TetR/ACRR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2461 | - | 3e-97 | 86.43% (199) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0302 | - | 2e-13 | 30.17% (179) | TetR/ACRR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 6e-08 | 37.50% (72) | putative TetR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3437c | - | 1e-16 | 33.16% (190) | TetR family transcriptional regulator |
| M. marinum M | MMAR_4631 | - | 1e-15 | 32.47% (194) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 2e-14 | 28.90% (173) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 6e-52 | 51.04% (192) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4015 | - | 7e-09 | 44.26% (61) | PUTATIVE - |
| M. ulcerans Agy99 | MUL_0245 | - | 2e-12 | 30.51% (177) | transcriptional regulatory protein |
CLUSTAL 2.0.9 multiple sequence alignment
Mb0310|M.bovis_AF2122/97 -------------------------MGVPAKKKQQQGERSRESILDATER
Rv0302|M.tuberculosis_H37Rv -------------------------MGVPAKKKQQQGERSRESILDATER
Mvan_4193|M.vanbaalenii_PYR-1 --------------------------MAERWTRQRRVEHTRTLLLDAAEE
Mflv_2461|M.gilvum_PYR-GCK MYLRYKNKYFFRGRLPATDGAGNNGGVAERWTRQRRVDHTRALLLDAAEE
MSMEG_6807|M.smegmatis_MC2_155 --------------------------MVERWTRERRLEHTRSLLLDAAEN
MMAR_4631|M.marinum_M --------------------MTPPANTATPARVTKRRAETRARLVDAAFR
MUL_0245|M.ulcerans_Agy99 --------------------------------------------------
MAB_3437c|M.abscessus_ATCC_199 --------------------------MSKRLSRTESQELTRAKLIESATR
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
TH_4015|M.thermoresistible__bu -VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKE
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
Mb0310|M.bovis_AF2122/97 LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Rv0302|M.tuberculosis_H37Rv LMATKGYAATSISDIRDACGLAPSSIYWHFGSKEGVLAAMMERGAQRFFA
Mvan_4193|M.vanbaalenii_PYR-1 VVARLGFGAAALEVIADAAGYTRGAIYSHFGTKEELFLAVMERQLQRFLD
Mflv_2461|M.gilvum_PYR-GCK VVARQGFGAAALEVIADAAGYTRGAIYAHFGTKEELFLAVMERQLQRFLD
MSMEG_6807|M.smegmatis_MC2_155 VFSEKGFTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFD
MMAR_4631|M.marinum_M VFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MUL_0245|M.ulcerans_Agy99 MFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MAB_3437c|M.abscessus_ATCC_199 LYLENGYVATSTDQVAEAAGFSRGALYSNFRSKEDLALAVLDAHTEEQFQ
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
TH_4015|M.thermoresistible__bu VFARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQ
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
: *: . : .* : .* * : : :
Mb0310|M.bovis_AF2122/97 AIPTWDEAHGPVEQRS---ERQLTELVSLQSQH-PDFLRLFYLLSMERSQ
Rv0302|M.tuberculosis_H37Rv AIPTWDEAHGPVEQRS---ERQLTELVSLQSQH-PDFLRLFYLLSMERSQ
Mvan_4193|M.vanbaalenii_PYR-1 GFTDIVESFQSLEELD--VDKLAGRWRELTIGN-PDRAALGYEFTLFLVR
Mflv_2461|M.gilvum_PYR-GCK GFTDIVESFRSLEEMD--VDRLAGRWRELTIGN-PDRAALGYEFTLFLVR
MSMEG_6807|M.smegmatis_MC2_155 NFAEVMASAASVGARE--LDEIAKRWRQLSVDRGAEQAALGLEFTLYLKR
MMAR_4631|M.marinum_M QVGTAMASVDDPTDVPGTVDRIAS---TLLLDR--DWLLIKTDFLMHAAR
MUL_0245|M.ulcerans_Agy99 QVGTAMASVGDPTDVPGTVDRIAS---TLLLDR--DWLLIKTDFLMHAAR
MAB_3437c|M.abscessus_ATCC_199 EIAAVAADLPPERFTR------FETWLTKSMGD-RRWALFKSEVALSARA
MAV_1611|M.avium_104 QIAIALDRSAGDTTAA---AREVSRSVLDSVRDHSDYYVLLVEYWLRAQR
TH_4015|M.thermoresistible__bu PVRTDAGTEPKNPYER----ILRANRTYLEAYRANRAIMIVWEQVASLNE
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRL---HAAVQAFFDFIEHDGQGYRLIFENDNITEPR
. :
Mb0310|M.bovis_AF2122/97 DPVVAAVVRRVRNTAIARFRDSITHLLPS--DIPPGKADLVVAELTAFAV
Rv0302|M.tuberculosis_H37Rv DPAVAAVVRRVRNTAIARFRDSITHLLPS--DIPPGKADLVVAELTAFAV
Mvan_4193|M.vanbaalenii_PYR-1 NPEARARVAAQRRQTADSLAGYITSHI----EKIGGRMRVPAATLARVLI
Mflv_2461|M.gilvum_PYR-GCK NPEARVRVAEQRRRTADSLAEYISVHV----EKIGGRLRIPAPTLARILI
MSMEG_6807|M.smegmatis_MC2_155 NPEARDRVAAKRSEVVAQLTAFIVASI----EKLGATLLISPETFAHALV
MMAR_4631|M.marinum_M HPDLAQRLAAHRAQLRAAVEDRLAGSD----VELPAAIGS-VADAARAVV
MUL_0245|M.ulcerans_Agy99 HPDLAQRLAAHRAQLRAAVEDRLAGSD----VELPAAIGS-VADAARAVV
MAB_3437c|M.abscessus_ATCC_199 NPELRQQLAARDQLARQALSVLLGHVE----AESGNPLPAAPETLARAIL
MAV_1611|M.avium_104 DPQLRERLIERRRAAADQALHIVESTD-------TVPGDRRLTDIAQLVV
TH_4015|M.thermoresistible__bu HVEQLRREYSDRFAARIERAIIRWQEAGL--ADPAIDPRYAAAALSGMLS
MLBr_00815|M.leprae_Br4923 VAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARYWL
:
Mb0310|M.bovis_AF2122/97 ALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET-----
Rv0302|M.tuberculosis_H37Rv ALSDGVYFAGHLEPDTTDVERMYRRLRQALEALIPVLLEET-----
Mvan_4193|M.vanbaalenii_PYR-1 ATNEGVTLGSHVDG-----EDLFRPFLEMVLGNVEPAG--------
Mflv_2461|M.gilvum_PYR-GCK ATYEGITLGGHIDG-----EDLARPFLELVLADVQPAESPDSERWD
MSMEG_6807|M.smegmatis_MC2_155 ATSDSVVLSSELDN-----VDLYRPMVEMYASMIKLPT--------
MMAR_4631|M.marinum_M AAYDGVSIQLLLDGD----QDAARAWLSQLLGVVLIR---------
MUL_0245|M.ulcerans_Agy99 AAYDGVSIQLLLDGD----QDAARAWLSQLLGVVLIR---------
MAB_3437c|M.abscessus_ATCC_199 ALAKGIAIEGLVDD------EVSPDWIIDLVKKGLPQ---------
MAV_1611|M.avium_104 TLNLGVAMEEVLRPG-----TINPDLLAQLITALLESIPV------
TH_4015|M.thermoresistible__bu NFAYRWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA---
MLBr_00815|M.leprae_Br4923 DTNRPISKSDAVEG------TVQFAWGGLSHVPLTRL---------