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LYPYRFTVITTGRLLMSTGSTRRREHTRARLMQAALDVFADRGFHGASIENICEKAGFTRGAFYSNFAGK DELFFTLFDASSEQLLTQLRAALDECRKSPDPLSTFIRTIDDKGPTQRRWYLISMEFTLYAIREPSAAVV LAEHDARLRREAAGIINELMSIAHRELIIDTELIARLATALREGVAAQFYVEPELAETRMLERLAFPAML RAFSQPVGAD
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_2913 | - | - | 100% (220) | TetR family regulatory protein |
| M. abscessus ATCC 19977 | MAB_3437c | - | 1e-17 | 29.55% (176) | TetR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_1379c | - | 2e-11 | 27.32% (183) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3233 | - | 3e-09 | 26.61% (124) | TetR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 1e-19 | 31.87% (182) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3208 | - | 3e-09 | 26.61% (124) | TetR family transcriptional regulator |
| M. leprae Br4923 | MLBr_00815 | - | 1e-08 | 31.43% (70) | putative TetR-family transcriptional regulator |
| M. marinum M | MMAR_4631 | - | 3e-22 | 44.36% (133) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 2e-17 | 32.42% (182) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0148 | - | 6e-17 | 30.60% (183) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_0452 | - | 2e-09 | 34.67% (75) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_0245 | - | 6e-17 | 41.96% (112) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 2e-18 | 32.24% (183) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2327|M.gilvum_PYR-GCK --------------------------MAERWTKERRTEHTRQILLDAAEE
Mvan_4321|M.vanbaalenii_PYR-1 --------------------------MAERWTKERRTEHTRQILLDAAEE
MMAR_4631|M.marinum_M --------------------MTPPANTATPARVTKRRAETRARLVDAAFR
MUL_0245|M.ulcerans_Agy99 --------------------------------------------------
Mb3233|M.bovis_AF2122/97 MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
Rv3208|M.tuberculosis_H37Rv MSDLAKTAQRRALRSSGSARPDEDVPAPNRRGNRLPRDERRGQLLVVASD
MLBr_00815|M.leprae_Br4923 MNNLAKAAQRRTVRPIDRGRLSDDIATPNQRSNRLSRDKRRGQLLIVASD
TH_0452|M.thermoresistible__bu MSEVADTTARQEITPTNGGTTSGAAAGANRRGNRLPRDERRNQLLIAASE
MAB_2913|M.abscessus_ATCC_1997 -------------MYPYRFTVITTGRLLMSTGSTRRREHTRARLMQAALD
MSMEG_0148|M.smegmatis_MC2_155 ------------------------MVPRKRLTRAEARAQTRRRLLDAAAE
MAV_1611|M.avium_104 --------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAK
Mflv_2327|M.gilvum_PYR-GCK VFARKGLTGAALEEIADAAGFTRGAIYSQFGAKEKLFLAVVDRQRERFLD
Mvan_4321|M.vanbaalenii_PYR-1 VFARKGLTGAALEEIAEAAGFTRGAIYSQFGAKEKLFLAVVDRQRQRFLD
MMAR_4631|M.marinum_M VFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
MUL_0245|M.ulcerans_Agy99 MFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISE
Mb3233|M.bovis_AF2122/97 VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
Rv3208|M.tuberculosis_H37Rv VFVDRGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLHRHVENLVS
MLBr_00815|M.leprae_Br4923 VFVDHGYHAAGMDEIADRAGVSKPVLYQHFSSKLELYLAVLERHMNNLVS
TH_0452|M.thermoresistible__bu VFVDRGYHAAGMDEIAERAGVSKPVLYQHFSSKLELYLAVLQRHVDNLVS
MAB_2913|M.abscessus_ATCC_1997 VFADRGFHGASIENICEKAGFTRGAFYSNFAGKDELFFTLFDASSEQLLT
MSMEG_0148|M.smegmatis_MC2_155 TFARKGYDAASVEEIAEAAGYSVGAVYSNFSSKEQLFSELRSERAALRLD
MAV_1611|M.avium_104 VFAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQ
*. .* . :: : ** : ..*.:* . :*: :
Mflv_2327|M.gilvum_PYR-GCK GFADVMDSFHR-LSDVD--IDELAQRWRQLSSGADRAALGYELTLYLLRN
Mvan_4321|M.vanbaalenii_PYR-1 GFADVMMSFHR-LSDVD--IDELAERWRQLSSGPDRAALGHELTLYLLRN
MMAR_4631|M.marinum_M QVGTAMASVDD-PTDVPGTVDRIAS---TLLLDRDWLLIKTDFLMHAARH
MUL_0245|M.ulcerans_Agy99 QVGTAMASVGD-PTDVPGTVDRIAS---TLLLDRDWLLIKTDFLMHAARH
Mb3233|M.bovis_AF2122/97 GVHQALSTTTDNRQRLHVAVQAFFD-----FIEHDSQGYRLIFENDFVTE
Rv3208|M.tuberculosis_H37Rv GVHQALSTTTDNRQRLHVAVQAFFD-----FIEHDSQGYRLIFENDFVTE
MLBr_00815|M.leprae_Br4923 SVQQALRTTTNNRQRLHAAVQAFFD-----FIEHDGQGYRLIFENDNITE
TH_0452|M.thermoresistible__bu GVRQALRTTTDNRQRLRAAVQAFFD-----FIEHDGQGYRLIFENDYVTE
MAB_2913|M.abscessus_ATCC_1997 QLRAALDECRKSPDPLSTFIRTIDD---KGPTQRRWYLISMEFTLYAIRE
MSMEG_0148|M.smegmatis_MC2_155 EVADALRSAQGDPGGPFAKLSRQLV--EVADKNIEVAALHTEFWLHAIRN
MAV_1611|M.avium_104 QIAIALDRSAGDTTAAAREVSRSVLD--SVRDHSDYYVLLVEYWLRAQRD
. .: : .
Mflv_2327|M.gilvum_PYR-GCK PDARASVAAQRRETIRALGEFISKN-------VARIGGTLTIEAETLARI
Mvan_4321|M.vanbaalenii_PYR-1 PEARESVAGQRRETVRALGEFISKN-------VARIGGTLTIEAETLARV
MMAR_4631|M.marinum_M PDLAQRLAAHRAQLRAAVEDRLAGS-------DVELPAAIGSVAD-AARA
MUL_0245|M.ulcerans_Agy99 PDLAQRLAAHRAQLRAAVEDRLAGS-------DVELPAAIGSVAD-AARA
Mb3233|M.bovis_AF2122/97 PEVAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARY
Rv3208|M.tuberculosis_H37Rv PEVAAQVRVATESCIDAVFALISADSGLDPHRARMIAVGLVGMSVDCARY
MLBr_00815|M.leprae_Br4923 PRVAAQVRVATESCIDAVFALISADSRLDPHRARMVAVGLVGISVDCARY
TH_0452|M.thermoresistible__bu PQVAAQVKVATEACTDAVFDLISQDSGLEAHRARMIAVGLVAISVDCARY
MAB_2913|M.abscessus_ATCC_1997 PSAAVVLAEHDARLRREAAGIINEL-------MSIAHRELIIDTELIARL
MSMEG_0148|M.smegmatis_MC2_155 PGAMDVLAESVGQTLQSLTGIAADL------LAEHNVDQSVVRPETFAVS
MAV_1611|M.avium_104 PQLRERLIERRRAAADQALHIVEST----------DTVPGDRRLTDIAQL
* : *
Mflv_2327|M.gilvum_PYR-GCK VLAANDGVTLDSHIDGE-DLYRPYLQLVMSSVQTPH-------
Mvan_4321|M.vanbaalenii_PYR-1 VLAANDGITLNSHLDGE-DLYRPYLQLVISSVQTPP-------
MMAR_4631|M.marinum_M VVAAYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR--------
MUL_0245|M.ulcerans_Agy99 VVAAYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR--------
Mb3233|M.bovis_AF2122/97 WLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS----------
Rv3208|M.tuberculosis_H37Rv WLDADKPISKSDAVEGTVQFAWGGLSHVPLTRS----------
MLBr_00815|M.leprae_Br4923 WLDTNRPISKSDAVEGTVQFAWGGLSHVPLTRL----------
TH_0452|M.thermoresistible__bu WLHADRPISKEDAVEGTVQFAWGGLSHVPLTRS----------
MAB_2913|M.abscessus_ATCC_1997 ATALREGVAAQFYVEPELAETRMLERLAFPAMLRAFSQPVGAD
MSMEG_0148|M.smegmatis_MC2_155 LLALHQGLIRQRRTNPSWVPEELFGQLLSWLLAGMPKLPAH--
MAV_1611|M.avium_104 VVTLNLGVAMEEVLRPGTINPDLLAQLITALLESIPV------
: .