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FADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISEQVGTAMASVGDPTDVPGTVDR IASTLLLDRDWLLIKTDFLMHAARHPDLAQRLAAHRAQLRAAVEDRLAGSDVELPAAIGSVADAARAVVA AYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. ulcerans Agy99 | MUL_0245 | - | - | 100% (173) | transcriptional regulatory protein |
| M. ulcerans Agy99 | MUL_0145 | - | 5e-07 | 32.81% (64) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1561 | - | 6e-06 | 34.85% (66) | transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 3e-13 | 29.31% (174) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv1534 | - | 6e-06 | 34.85% (66) | transcriptional regulator |
| M. leprae Br4923 | MLBr_02121 | - | 7e-28 | 63.16% (95) | hypothetical protein MLBr_02121 |
| M. abscessus ATCC 19977 | MAB_2913 | - | 5e-17 | 41.96% (112) | TetR family regulatory protein |
| M. marinum M | MMAR_4631 | - | 2e-93 | 99.42% (173) | transcriptional regulatory protein |
| M. avium 104 | MAV_1611 | - | 3e-13 | 32.26% (155) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_6807 | - | 5e-11 | 30.19% (159) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4015 | - | 3e-06 | 42.59% (54) | PUTATIVE - |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 5e-13 | 28.16% (174) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2327|M.gilvum_PYR-GCK -------------------MAERWTKERR------TEHTRQILLDAAEEV
Mvan_4321|M.vanbaalenii_PYR-1 -------------------MAERWTKERR------TEHTRQILLDAAEEV
MSMEG_6807|M.smegmatis_MC2_155 -------------------MVERWTRERR------LEHTRSLLLDAAENV
Mb1561|M.bovis_AF2122/97 -------------------MSRASARRRRAVSDEDKSQRRDEILAAAKIV
Rv1534|M.tuberculosis_H37Rv -------------------MSRASARRRRAVSDEDKSQRRDEILAAAKIV
MUL_0245|M.ulcerans_Agy99 -------------------------------------------------M
MMAR_4631|M.marinum_M -------------------MTPPANTATPARVTKRRAETRARLVDAAFRV
MLBr_02121|M.leprae_Br4923 -------------------------------------------------M
MAB_2913|M.abscessus_ATCC_1997 ------------MYPYRFTVITTGRLLMSTGSTRRREHTRARLMQAALDV
MAV_1611|M.avium_104 -------------------MLLGMSPVKPLRSRPTRGEVRDRILDAAAKV
TH_4015|M.thermoresistible__bu VVPRRRVDNGSNEQGVASDATGGDRMNRPLPPTARGRRSRRALLDAAKEV
:
Mflv_2327|M.gilvum_PYR-GCK FARKGLTGAALEEIADAAGFTRGAIYSQFGAKEKLFLAVVDRQRERFLDG
Mvan_4321|M.vanbaalenii_PYR-1 FARKGLTGAALEEIAEAAGFTRGAIYSQFGAKEKLFLAVVDRQRQRFLDG
MSMEG_6807|M.smegmatis_MC2_155 FSEKGFTAATLDDIAFAAGYTKGAIYKHFATKEDLFLAVSDRYWRRYFDN
Mb1561|M.bovis_AF2122/97 FAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAH
Rv1534|M.tuberculosis_H37Rv FAHKGFHATTVADIAKQAGLAYGLIYWYFDSKDDLFHALMAGEEEALRAH
MUL_0245|M.ulcerans_Agy99 FADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISEQ
MMAR_4631|M.marinum_M FADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISEQ
MLBr_02121|M.leprae_Br4923 YG----GRLHPRGVLLAVRSPRGIVLRALRPARD-----HNHRT------
MAB_2913|M.abscessus_ATCC_1997 FADRGFHGASIENICEKAGFTRGAFYSNFAGKDELFFTLFDASSEQLLTQ
MAV_1611|M.avium_104 FAAEGFAGATIDAIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQQ
TH_4015|M.thermoresistible__bu FARDGFADARITDIADAAGTAHGSFYRYFDSKEEIFIELLRELVEELRQP
:. : . . * . : .
Mflv_2327|M.gilvum_PYR-GCK FADVMDSFHRLSDVDIDELAQRWRQLSS---GADRAALGYELTLYLLRNP
Mvan_4321|M.vanbaalenii_PYR-1 FADVMMSFHRLSDVDIDELAERWRQLSS---GPDRAALGHELTLYLLRNP
MSMEG_6807|M.smegmatis_MC2_155 FAEVMASAASVGARELDEIAKRWRQLSVDR-GAEQAALGLEFTLYLKRNP
Mb1561|M.bovis_AF2122/97 VAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGG
Rv1534|M.tuberculosis_H37Rv VAAELARVGGSTEAPLRALLQAAVQATFEFFETDKATVKLLFRDAYALGG
MUL_0245|M.ulcerans_Agy99 VGTAMASVG--DPTDVPGTVDRIASTLL--LDRDWLLIKTDFLMHAARHP
MMAR_4631|M.marinum_M VGTAMASVD--DPTDVPGTVDRIASTLL--LDRDWLLIKTDFLMHAARHP
MLBr_02121|M.leprae_Br4923 AQPAIAGAG--ESADLVELVDRVAATLL--LDPDWLLVKTDFLMHAGCHP
MAB_2913|M.abscessus_ATCC_1997 LRAALDECRK-SPDPLSTFIRTIDDKGP--TQRRWYLISMEFTLYAIREP
MAV_1611|M.avium_104 IAIALDRSAGDTTAAAREVSRSVLDSVR--DHSDYYVLLVEYWLRAQRDP
TH_4015|M.thermoresistible__bu VRTDAGTEPKNPYERILRANRTYLEAYR-----ANRAIMIVWEQVASLNE
:
Mflv_2327|M.gilvum_PYR-GCK DARASVAAQRRETIRALGEFISKNVAR----IGGTLTIEAETLARIVLAA
Mvan_4321|M.vanbaalenii_PYR-1 EARESVAGQRRETVRALGEFISKNVAR----IGGTLTIEAETLARVVLAA
MSMEG_6807|M.smegmatis_MC2_155 EARDRVAAKRSEVVAQLTAFIVASIEK----LGATLLISPETFAHALVAT
Mb1561|M.bovis_AF2122/97 RFEEHLGGIYERFIDDIEAVVVAAQRRGEV-VEAPSRMAAYTLAALVGQL
Rv1534|M.tuberculosis_H37Rv RFEEHLGGIYERFIDDIEAVVVAAQRRGEV-VEAPSRMAAYTLAALVGQL
MUL_0245|M.ulcerans_Agy99 DLAQRLAAHRAQLRAAVEDRLAGSDVEL------PAAIGSVADAARAVVA
MMAR_4631|M.marinum_M DLAQRLAAHRAQLRAAVEDRLAGSDVEL------PAAIGSVADAARAVVA
MLBr_02121|M.leprae_Br4923 DLIQCLVAQRAKLRVAIEDRFS-SAIEL------PNAIGTMGNAACVVVA
MAB_2913|M.abscessus_ATCC_1997 SAAVVLAEHDARLRREAAGIINELMSIA----HRELIIDTELIARLATAL
MAV_1611|M.avium_104 QLRERLIERRRAAADQALHIVESTDTVP-------GDRRLTDIAQLVVTL
TH_4015|M.thermoresistible__bu HVEQLRREYSDRFAARIERAIIRWQEAGLADPAIDPRYAAAALSGMLSNF
. :
Mflv_2327|M.gilvum_PYR-GCK NDG-VTLDSHIDGEDLYRPYLQLVMSSVQTPH-------------
Mvan_4321|M.vanbaalenii_PYR-1 NDG-ITLNSHLDGEDLYRPYLQLVISSVQTPP-------------
MSMEG_6807|M.smegmatis_MC2_155 SDS-VVLSSELDNVDLYRPMVEMYASMIKLPT-------------
Mb1561|M.bovis_AF2122/97 AHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
Rv1534|M.tuberculosis_H37Rv AHRRLNTDDNVTAAQVADFVVSLVLDGLRPRALAVGARGGRAART
MUL_0245|M.ulcerans_Agy99 AYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR-------------
MMAR_4631|M.marinum_M AYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR-------------
MLBr_02121|M.leprae_Br4923 AYDGVSIQP--------AR--------------------------
MAB_2913|M.abscessus_ATCC_1997 REG-VAAQFYVEPELAETRMLERLAFPAMLRAFSQPVGAD-----
MAV_1611|M.avium_104 NLG-VAMEEVLRPGTINPDLLAQLITALLESIPV-----------
TH_4015|M.thermoresistible__bu AYRWSVQDADYDLDTAAEQLSLLWANALGVRVPAHHEPAHA----
.