For questions or suggestions e-mail us at: ioerger@cs.tamu.edu
TPPANTATPARVTKRRAETRARLVDAAFRVFADKGFGHVRIEDVCAAAGYTRGAFYSQFDSLEELFFTLY DQRATLISEQVGTAMASVDDPTDVPGTVDRIASTLLLDRDWLLIKTDFLMHAARHPDLAQRLAAHRAQLR AAVEDRLAGSDVELPAAIGSVADAARAVVAAYDGVSIQLLLDGDQDAARAWLSQLLGVVLIR*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4631 | - | - | 100% (203) | transcriptional regulatory protein |
| M. marinum M | MMAR_3853 | - | 1e-09 | 31.91% (141) | putative regulatory protein |
| M. marinum M | MMAR_4335 | - | 8e-09 | 33.33% (75) | TetR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb3093 | - | 8e-08 | 25.28% (178) | DeoR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_2327 | - | 2e-16 | 30.53% (190) | TetR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv3066 | - | 8e-08 | 25.28% (178) | DeoR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02121 | - | 6e-27 | 62.11% (95) | hypothetical protein MLBr_02121 |
| M. abscessus ATCC 19977 | MAB_2913 | - | 2e-22 | 44.36% (133) | TetR family regulatory protein |
| M. avium 104 | MAV_1611 | - | 4e-17 | 32.95% (176) | transcriptional regulator, TetR family protein |
| M. smegmatis MC2 155 | MSMEG_0148 | - | 6e-15 | 34.93% (146) | transcriptional regulator, TetR family protein |
| M. thermoresistible (build 8) | TH_4000 | - | 7e-10 | 28.50% (200) | PUTATIVE transcriptional regulator, TetR family |
| M. ulcerans Agy99 | MUL_0245 | - | 2e-93 | 99.42% (173) | transcriptional regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_4321 | - | 4e-16 | 29.47% (190) | TetR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2327|M.gilvum_PYR-GCK -------------MAERWTKERRTEHTRQILLDAAEEVFARKGLTGAALE
Mvan_4321|M.vanbaalenii_PYR-1 -------------MAERWTKERRTEHTRQILLDAAEEVFARKGLTGAALE
MMAR_4631|M.marinum_M -------MTPPANTATPARVTKRRAETRARLVDAAFRVFADKGFGHVRIE
MUL_0245|M.ulcerans_Agy99 -------------------------------------MFADKGFGHVRIE
MLBr_02121|M.leprae_Br4923 -------------------------------------MYG----GRLHPR
Mb3093|M.bovis_AF2122/97 ------------MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHR
Rv3066|M.tuberculosis_H37Rv ------------MTAGSDRRPRDPAGRRQAIVEAAERVIARQGLGGLSHR
MAB_2913|M.abscessus_ATCC_1997 MYPYRFTVITTGRLLMSTGSTRRREHTRARLMQAALDVFADRGFHGASIE
MSMEG_0148|M.smegmatis_MC2_155 -----------MVPRKRLTRAEARAQTRRRLLDAAAETFARKGYDAASVE
MAV_1611|M.avium_104 -------MLLGMSPVKPLRSRPTRGEVRDRILDAAAKVFAAEGFAGATID
TH_4000|M.thermoresistible__bu --------MTSPTRWAGVPLTDRRAERRALLIAAAYRLFGEGGEAALSVR
.
Mflv_2327|M.gilvum_PYR-GCK EIADAAGFTRGAIYSQFGAKEKLFLAVVDRQRERFLDGFADVMDSFH---
Mvan_4321|M.vanbaalenii_PYR-1 EIAEAAGFTRGAIYSQFGAKEKLFLAVVDRQRQRFLDGFADVMMSFH---
MMAR_4631|M.marinum_M DVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISEQVGTAMASVD---
MUL_0245|M.ulcerans_Agy99 DVCAAAGYTRGAFYSQFDSLEELFFTLYDQRATLISEQVGTAMASVG---
MLBr_02121|M.leprae_Br4923 GVLLAVRSPRGIVLRALRPARD-----HNHRT------AQPAIAGAG---
Mb3093|M.bovis_AF2122/97 RVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLAQWRSDLD---
Rv3066|M.tuberculosis_H37Rv RVAAEANVPVGSTTYYFNDLDALREAALAHAANASADLLAQWRSDLD---
MAB_2913|M.abscessus_ATCC_1997 NICEKAGFTRGAFYSNFAGKDELFFTLFDASSEQLLTQLRAALDECR---
MSMEG_0148|M.smegmatis_MC2_155 EIAEAAGYSVGAVYSNFSSKEQLFSELRSERAALRLDEVADALRSAQG--
MAV_1611|M.avium_104 AIGQAAGFTKGAVYSNFESKDELFLALLDREFELRGQQIAIALDRSAG--
TH_4000|M.thermoresistible__bu SVCRESELNSRYFYESFADVDELLGAVYDEVSAQLAAEVETAMAAAVEGA
: :
Mflv_2327|M.gilvum_PYR-GCK ---RLSDVDIDELAQRWRQLSSGADRAALGYELTLYLLRNPDARASVAAQ
Mvan_4321|M.vanbaalenii_PYR-1 ---RLSDVDIDELAERWRQLSSGPDRAALGHELTLYLLRNPEARESVAGQ
MMAR_4631|M.marinum_M ---DPTDV-PGTVDRIASTLLLDRDWLLIKTDFLMHAARHPDLAQRLAAH
MUL_0245|M.ulcerans_Agy99 ---DPTDV-PGTVDRIASTLLLDRDWLLIKTDFLMHAARHPDLAQRLAAH
MLBr_02121|M.leprae_Br4923 ---ESADL-VELVDRVAATLLLDPDWLLVKTDFLMHAGCHPDLIQCLVAQ
Mb3093|M.bovis_AF2122/97 ---KDRDL-AATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLW
Rv3066|M.tuberculosis_H37Rv ---KDRDL-AATLARLTTVYLADQDRYRTLNELYMAAAHRPELQRLARLW
MAB_2913|M.abscessus_ATCC_1997 ---KSPDPLSTFIRTIDDKGPTQRRWYLISMEFTLYAIREPSAAVVLAEH
MSMEG_0148|M.smegmatis_MC2_155 ---DPGGPFAKLSRQLVEVADKNIEVAALHTEFWLHAIRNPGAMDVLAES
MAV_1611|M.avium_104 ---DTTAAAREVSRSVLDSVRDHSDYYVLLVEYWLRAQRDPQLRERLIER
TH_4000|M.thermoresistible__bu GEGAGDSLRARTRAGIVAVLGFSSADPRRGRILFTDARANPVLAARRAAT
*
Mflv_2327|M.gilvum_PYR-GCK RRETIRALGEFISK---NVARIGGTLTIEAETLARIVLAANDGVTLDSHI
Mvan_4321|M.vanbaalenii_PYR-1 RRETVRALGEFISK---NVARIGGTLTIEAETLARVVLAANDGITLNSHL
MMAR_4631|M.marinum_M RAQLRAAVEDRLAG---SDVELPAAIGSVADAARAVVAAYDGVSIQLLLD
MUL_0245|M.ulcerans_Agy99 RAQLRAAVEDRLAG---SDVELPAAIGSVADAARAVVAAYDGVSIQLLLD
MLBr_02121|M.leprae_Br4923 RAKLRVAIEDRFS----SAIELPNAIGTMGNAACVVVAAYDGVSIQP---
Mb3093|M.bovis_AF2122/97 PDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL
Rv3066|M.tuberculosis_H37Rv PDGLLALLEPRIGRRAANAVTVFFDGATLHALITGTPLSTDELTDAIARL
MAB_2913|M.abscessus_ATCC_1997 DARLRREAAGIINE---LMSIAHRELIIDTELIARLATALREGVAAQFYV
MSMEG_0148|M.smegmatis_MC2_155 VGQTLQSLTGIAAD--LLAEHNVDQSVVRPETFAVSLLALHQGLIRQRRT
MAV_1611|M.avium_104 RRAAADQALHIVES------TDTVPGDRRLTDIAQLVVTLNLGVAMEEVL
TH_4000|M.thermoresistible__bu QDQLREAVLTEGWR-----LHPKSDPVAAQVGAAMYTGAMAELAQQWLAG
:
Mflv_2327|M.gilvum_PYR-GCK DGEDLYRPYLQLVMSSVQTPH--------
Mvan_4321|M.vanbaalenii_PYR-1 DGEDLYRPYLQLVISSVQTPP--------
MMAR_4631|M.marinum_M GDQDAARAWLSQLLGVVLIR---------
MUL_0245|M.ulcerans_Agy99 GDQDAARAWLSQLLGVVLIR---------
MLBr_02121|M.leprae_Br4923 -----AR----------------------
Mb3093|M.bovis_AF2122/97 VADGPEQREVGQSAHAGRTPD--------
Rv3066|M.tuberculosis_H37Rv VADGPEQREVGQSAHAGRTPD--------
MAB_2913|M.abscessus_ATCC_1997 EPELAETRMLERLAFPAMLRAFSQPVGAD
MSMEG_0148|M.smegmatis_MC2_155 NPSWVPEELFGQLLSWLLAGMPKLPAH--
MAV_1611|M.avium_104 RPGTINPDLLAQLITALLESIPV------
TH_4000|M.thermoresistible__bu NLGDDLDRVVDYALRLVLGR---------