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MPAPCGVRFDTMAQRILVIGAGIAGLATAVAMQRRGYAVTVVKERTDTSSGAGISIWPNALAALDRIGVG QAVRDAGGRITAGALRWRDGSWLRRPAFTLPKG
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_4556 | - | - | 100% (103) | monooxygenase |
| M. avium 104 | MAV_4429 | - | 3e-07 | 35.21% (71) | FAD binding domain-containing protein |
| M. avium 104 | MAV_1408 | - | 2e-06 | 35.80% (81) | hypothetical protein MAV_1408 |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1290 | - | 5e-07 | 33.71% (89) | hypothetical protein Mb1290 |
| M. gilvum PYR-GCK | Mflv_2621 | - | 3e-33 | 68.60% (86) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv1260 | - | 6e-07 | 33.71% (89) | hypothetical protein Rv1260 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_1601c | - | 4e-23 | 56.47% (85) | putative monooxygenase |
| M. marinum M | MMAR_4180 | - | 4e-10 | 35.16% (91) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_4641 | - | 8e-32 | 72.09% (86) | salicylate hydroxylase |
| M. thermoresistible (build 8) | TH_2138 | - | 5e-05 | 47.17% (53) | D-amino-acid dehydrogenase |
| M. ulcerans Agy99 | MUL_4482 | - | 1e-10 | 36.26% (91) | hypothetical protein MUL_4482 |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 6e-33 | 72.09% (86) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1290|M.bovis_AF2122/97 ------------MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRP
Rv1260|M.tuberculosis_H37Rv ------------MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRP
MMAR_4180|M.marinum_M ---------MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVERHPGLRP
MUL_4482|M.ulcerans_Agy99 ---------MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVERHPGLRP
Mflv_2621|M.gilvum_PYR-GCK -----------MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTGA
Mvan_3960|M.vanbaalenii_PYR-1 -----------MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLTS
MSMEG_4641|M.smegmatis_MC2_155 -----------MAASFLVVGAGITGLATAAALQRRGHDVCVAEARADTAS
MAB_1601c|M.abscessus_ATCC_199 -----------MSDHIVVVGAGIAGLATAVAIQQSGRDVVVVDDRDGTSA
MAV_4556|M.avium_104 MPAPCGVRFDTMAQRILVIGAGIAGLATAVAMQRRGYAVTVVKERTDTSS
TH_2138|M.thermoresistible__bu MSQRFAERVDGGPRSAIVIGAGIVGLSTAWFLQERGVDVCVVDRTGVAAG
: **.: * ::* : . * * : .
Mb1290|M.bovis_AF2122/97 GGQAIDVRGP-------ALDVLERMGLLAAAQEHKTRIRGASFVDRDGNE
Rv1260|M.tuberculosis_H37Rv GGQAIDVRGP-------ALDVLERMGLLAAAQEHKTRIRGASFVDRDGNE
MMAR_4180|M.marinum_M GGQAIDVRGP-------ALTVLDRMGILDAARDRKTGIRGASVVDRDGNE
MUL_4482|M.ulcerans_Agy99 GGQAIDVRGP-------ALTVLDRMGILDAARDRKTGIRGASVVDRDGNE
Mflv_2621|M.gilvum_PYR-GCK G-SGISLWPN-------ALAALDQIGLGDSVRDAGGRVTAGAIRWRDGT-
Mvan_3960|M.vanbaalenii_PYR-1 G-AGISIWPN-------ALAALDQIGLGDNVRQAGGRVTAGAIRWRDGT-
MSMEG_4641|M.smegmatis_MC2_155 G-AGISIWPN-------ALAALDAIGLGDPVRAAGGRVTAGALRWHDGT-
MAB_1601c|M.abscessus_ATCC_199 G-YAITLWPN-------ALAACDALGIGEDVRAASARVEAGTMRWYDGR-
MAV_4556|M.avium_104 G-AGISIWPN-------ALAALDRIGVGQAVRDAGGRITAGALRWRDGS-
TH_2138|M.thermoresistible__bu ASWGNAGWISPGLAIPLNEPGVLRYGLRNLLSPTAPLHLPLTRDLRQWAF
. . *: : :
Mb1290|M.bovis_AF2122/97 LFRDTESTPTGGPVNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQ
Rv1260|M.tuberculosis_H37Rv LFRDTESTPTGGPVNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQ
MMAR_4180|M.marinum_M LSQDTESTPTGGPIDSPNIELLRDDLIELLYGTIQSTTEFIFDDSIATLQ
MUL_4482|M.ulcerans_Agy99 LSRDTESTPTGGPIDSPNIELLRDDLIELLDGTIQSTTEFIFDDSIATLQ
Mflv_2621|M.gilvum_PYR-GCK WVRRPSVRRIVDALGEPLVVVRRSRLTDILREALPA-GTVRTGLAATRVS
Mvan_3960|M.vanbaalenii_PYR-1 WLRRPSAQRIVHALGEPLVVVRRSALTEILLDALPP-DTVQTGLSATALS
MSMEG_4641|M.smegmatis_MC2_155 WLRHPAAERITRALGEPLVVIRRRVLTEILSGALAP-GTVVHGLEAHTVE
MAB_1601c|M.abscessus_ATCC_199 ILREPPSGKFTEAVGEPVAVTDRNQLLAILANRLTP-GTVRYGARVSNVR
MAV_4556|M.avium_104 WLRRP---------------------------------------------
TH_2138|M.thermoresistible__bu LTRFAANCRRSSWTRALLANKPLNDEAIEAYDVLTANGVDAPVTDAPITA
: .
Mb1290|M.bovis_AF2122/97 DDGDSVRVTFERAAAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHA
Rv1260|M.tuberculosis_H37Rv DDGDSVRVTFERAAAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHA
MMAR_4180|M.marinum_M DDGAAVEVTFVRSGTRTFDFLIGADGLHSNVRRKVFGPEEQFIKRLGTYA
MUL_4482|M.ulcerans_Agy99 DDGAAVEVTFVRSGTRTFDFLIGADGLHSNVRRKVFGPEEQFIKRLGTYA
Mflv_2621|M.gilvum_PYR-GCK VGASSVRITLSDGEVRESDAVVGADGVNSVLARTLNGPLRTRYVGYTAWR
Mvan_3960|M.vanbaalenii_PYR-1 IAAATARVTLSDGRTREADAVVGADGVNSMVARALNGPLPSRYVGYTAWR
MSMEG_4641|M.smegmatis_MC2_155 TCASGIRVTFSDGSVREASAVVGADGVDSVVARHLNGPLRRRYAGYTAWR
MAB_1601c|M.abscessus_ATCC_199 DGLHGTSVELADGQSLTAAAVIGADGIGSLVAQYLNGPLAFRYSGYTAWR
MAV_4556|M.avium_104 ------AFTLPKG-------------------------------------
TH_2138|M.thermoresistible__bu VFRDPREAGRLRDELRRVAETGRDVEVTELSGADLRERVPLASAEITVGL
Mb1290|M.bovis_AF2122/97 AIFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRID
Rv1260|M.tuberculosis_H37Rv AIFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRID
MMAR_4180|M.marinum_M AIFTVPNFLELDYWQKWHYGDNTMAGVYSARDNSEARAALGFMDTELQID
MUL_4482|M.ulcerans_Agy99 AIFTVPNFLELDYWQKWHYGDNTMAGVYSARDNSEARAALGFMDTELQID
Mflv_2621|M.gilvum_PYR-GCK GIAAHPLDPELG-------GETLGPGTQVGHVPLGPDHTYWFATERTAEG
Mvan_3960|M.vanbaalenii_PYR-1 GVAAYRLDPALA-------GETMSAGTEVGHVPLGPDHTYWFATERTREG
MSMEG_4641|M.smegmatis_MC2_155 GIAAHPLDPELS-------GETMGAGVEVGHVPLGADHTYWFATERASQG
MAB_1601c|M.abscessus_ATCC_199 GIADISIPDELA-------GLTVGPGIEFGHLPLSLGRTYWFAGERSLEA
MAV_4556|M.avium_104 --------------------------------------------------
TH_2138|M.thermoresistible__bu EIHGQRYVDPARFVQALADSVVDRGATIHRMDITGVDSGPGGVTVHSAGG
Mb1290|M.bovis_AF2122/97 YRDTEAQFAELQRRMAEDGWVRAQLLHYIAAH---------RISISTKCR
Rv1260|M.tuberculosis_H37Rv YRDTEAQFAELQRRMAEDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSR
MMAR_4180|M.marinum_M YRDTEAQFAELERRMIEDGWVRAQLLHYMRSAPDFYFDEMAQIVMDSWSK
MUL_4482|M.ulcerans_Agy99 YRDTEAQFAELERRMIEDGWVRAQLLHYMRSAPDFYFDEMAQIVMDSWAK
Mflv_2621|M.gilvum_PYR-GCK GSAPGGEHAYLTAKVADWADPIPRLVATTDPGDLLRNDLYDRARAARWSD
Mvan_3960|M.vanbaalenii_PYR-1 SRSAGGEHAYLTAKLAGWADPIPALLASTDPADVLRNDLYDRAQPRDWSR
MSMEG_4641|M.smegmatis_MC2_155 QRSPDGELTHLRRLFGSWAEPIPQLLAATDPADVLRNDLYDREPARCWAR
MAB_1601c|M.abscessus_ATCC_199 QRAPDGEIEYLARKFGNWADPIPRLLRQSRESSVLRGDVYDRGRLRRVAG
MAV_4556|M.avium_104 --------------------------------------------------
TH_2138|M.thermoresistible__bu QELSAGAVVIATGAWLHQLAQRWVRVPVQAGRGYSFTVPVDRPVPAPVYL
Mb1290|M.bovis_AF2122/97 RS------------------------------------------------
Rv1260|M.tuberculosis_H37Rv GRVALVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAGDDYQLGFANYH
MMAR_4180|M.marinum_M GRVALVGDAAYCCSPLSGQGTSVAVLGAYILAGELAAAGNDYQRGFANYH
MUL_4482|M.ulcerans_Agy99 GRVALVGDAAYCCSPLSGQGTSVAVLGAYILAGELAAAGNDYQRGFANYH
Mflv_2621|M.gilvum_PYR-GCK GRAVLIGDAAHPMRPHLGQGGCQGIEDAAILARFLELA-DDVPTAFERFE
Mvan_3960|M.vanbaalenii_PYR-1 GPAVIVGDAAHPMRPHLGQGGCQGLEDAAILARFVGLS-PDLPAAFDRFG
MSMEG_4641|M.smegmatis_MC2_155 GPVVLAGDAAHPMRPHLGQGGCQGLEDAATLAALVARE-PDLPTAFARFA
MAB_1601c|M.abscessus_ATCC_199 GRVVLVGDAAHPMRPHLGQGGCQSLEDAAVLSVAISER-SSLPSAFREYA
MAV_4556|M.avium_104 --------------------------------------------------
TH_2138|M.thermoresistible__bu PEVRVACTPCAAGLRVAGTMEFRDPDAPLISKRVDAIVAAARPLLDGVRW
Mb1290|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv AEFHG---------------FVERNQWLVSDNIPGGAPIPQEEFERIVHS
MMAR_4180|M.marinum_M AEFSG---------------FVERNQWLVTDNIPGGEPIPEEAFERIVNS
MUL_4482|M.ulcerans_Agy99 AEFSG---------------FGERNQWLVTDNIPGGEPIPEEAFERIVNS
Mflv_2621|M.gilvum_PYR-GCK AFRKPRVGMLVREAQTLGRIVNVRPAVLSGLAGRATALIPERMVTAHLAW
Mvan_3960|M.vanbaalenii_PYR-1 AFRRRRVRPLVRESAAIGRIVNLRPAFLSGVASRASALIPEWAVASHLAS
MSMEG_4641|M.smegmatis_MC2_155 TLRRRRVTRMVRTSRMIGRIVNLRPAVLSAAASRATVLVPEAVLTRQLAS
MAB_1601c|M.abscessus_ATCC_199 RRRRSRTRAVVSRSRHIGNVTFARPAVVGGLLTRASARIPASVFWRQLSS
MAV_4556|M.avium_104 --------------------------------------------------
TH_2138|M.thermoresistible__bu DERGPSWVGPRPVTPDGRPLIGAVAEDVYVAAGHGMWGLTHGPVTGRLLA
Mb1290|M.bovis_AF2122/97 -------------------
Rv1260|M.tuberculosis_H37Rv ITIKDY-------------
MMAR_4180|M.marinum_M LELEDYRQG----------
MUL_4482|M.ulcerans_Agy99 LELEDYRQG----------
Mflv_2621|M.gilvum_PYR-GCK IAAGSAFVLPTAADLAR--
Mvan_3960|M.vanbaalenii_PYR-1 IAAGSAFILPTAGDVGG--
MSMEG_4641|M.smegmatis_MC2_155 IAARSAFTPVD--------
MAB_1601c|M.abscessus_ATCC_199 IAGYEAGNLAVRP------
MAV_4556|M.avium_104 -------------------
TH_2138|M.thermoresistible__bu EQITTGKQPDVLDEFDPLR