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VKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAIDVRGPALDVLERMGLLAAAQEHKTRIR GASFVDRDGNELFRDTESTPTGGPVNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQDDGDSVRVT FERAAAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHAAIFTVPNFLELDYWQTWHYGDSTMAGVYS ARNNTEARAALAFMDTELRIDYRDTEAQFAELQRRMAEDGWVRAQLLHYIAAHRISISTKCRRS
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1290 | - | - | 100% (274) | hypothetical protein Mb1290 |
| M. bovis AF2122 / 97 | Mb0590c | - | 4e-36 | 44.56% (193) | hypothetical protein Mb0590c |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. gilvum PYR-GCK | Mflv_2621 | - | 4e-09 | 27.71% (166) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv1260 | - | 1e-149 | 99.62% (260) | hypothetical protein Rv1260 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_2678 | - | 1e-50 | 42.97% (263) | hypothetical protein MAB_2678 |
| M. marinum M | MMAR_4180 | - | 1e-120 | 78.46% (260) | oxidoreductase |
| M. avium 104 | MAV_1408 | - | 1e-117 | 79.23% (260) | hypothetical protein MAV_1408 |
| M. smegmatis MC2 155 | MSMEG_5719 | - | 1e-42 | 42.62% (244) | oxidoreductase |
| M. thermoresistible (build 8) | TH_0076 | - | 0.0001 | 39.47% (76) | phytoene dehydrogenase |
| M. ulcerans Agy99 | MUL_4482 | - | 1e-119 | 78.46% (260) | hypothetical protein MUL_4482 |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 9e-12 | 31.52% (165) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mflv_2621|M.gilvum_PYR-GCK ------MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTG--AGSG
Mvan_3960|M.vanbaalenii_PYR-1 ------MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLT--SGAG
Mb1290|M.bovis_AF2122/97 -------MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLR-PGGQA
Rv1260|M.tuberculosis_H37Rv -------MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLR-PGGQA
MAV_1408|M.avium_104 -------MSDVLVSGASVAGTAAAFWLGRHGHSVTVVERHRGPR-PGGQA
MMAR_4180|M.marinum_M ----MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVERHPGLR-PGGQA
MUL_4482|M.ulcerans_Agy99 ----MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVERHPGLR-PGGQA
MAB_2678|M.abscessus_ATCC_1997 --------MRVLISGASIAGPVLAFWLAHYGFEVTVIERSPAPRKSGGHA
MSMEG_5719|M.smegmatis_MC2_155 --------MKVLISGASIAGPVLAYWLSRHGFEVTVVERSPVLRKTGGHA
TH_0076|M.thermoresistible__bu MRTVTGRPDHIVVVGAGLAGLSAALHLAGRGRSVTVVERGAHPG-GRMGR
: **.::* * * * *:::*:
Mflv_2621|M.gilvum_PYR-GCK ISLWPNALAALDQIGLGDSVRDAGGRVTAGAIRWRDGTWVRRPSVR----
Mvan_3960|M.vanbaalenii_PYR-1 ISIWPNALAALDQIGLGDNVRQAGGRVTAGAIRWRDGTWLRRPSAQ----
Mb1290|M.bovis_AF2122/97 IDVRGPALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTES---T
Rv1260|M.tuberculosis_H37Rv IDVRGPALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTES---T
MAV_1408|M.avium_104 IDVRGPALGVLERMGLLAAAAKRRTQIRGSSVVDRDGNELSRDTEAAISG
MMAR_4180|M.marinum_M IDVRGPALTVLDRMGILDAARDRKTGIRGASVVDRDGNELSQDTES---T
MUL_4482|M.ulcerans_Agy99 IDVRGPALTVLDRMGILDAARDRKTGIRGASVVDRDGNELSRDTES---T
MAB_2678|M.abscessus_ATCC_1997 VDLFKPAMDIIEMMGILDHVEAQSAGT-EVLSIHREGK-RLIDLPE---V
MSMEG_5719|M.smegmatis_MC2_155 VDLFRPAMEISERMGVLPEIEAHATGT-TSMVVHRPGTSRPARLDY---L
TH_0076|M.thermoresistible__bu LDVHGYRLDTGPTVLTMPEILDETFAAVGSSVADRLDLKPVVPAYRAEFA
:.: : : * .
Mflv_2621|M.gilvum_PYR-GCK RIVDALGEPLVVVRRSRLTDILREALP--------AGTVRTGLAATRVSV
Mvan_3960|M.vanbaalenii_PYR-1 RIVHALGEPLVVVRRSALTEILLDALP--------PDTVQTGLSATALSI
Mb1290|M.bovis_AF2122/97 PTGGPVNSPDIELLRDDLVELLYGATQP-------SVEYLFDDSISTLQD
Rv1260|M.tuberculosis_H37Rv PTGGPVNSPDIELLRDDLVELLYGATQP-------SVEYLFDDSISTLQD
MAV_1408|M.avium_104 PTGGPIEGPDIELLRDDLVELLYGASQW-------TAEYLFDDTITALDD
MMAR_4180|M.marinum_M PTGGPIDSPNIELLRDDLIELLYGTIQS-------TTEFIFDDSIATLQD
MUL_4482|M.ulcerans_Agy99 PTGGPIDSPNIELLRDDLIELLDGTIQS-------TTEFIFDDSIATLQD
MAB_2678|M.abscessus_ATCC_1997 LIFSAVSERHVEIMRDDLSEILYGASAP-------SAEYIFGDSITALTD
MSMEG_5719|M.smegmatis_MC2_155 KVVGVISDRHIEIMRDDLSEIYFRAGRD-------DVEYLFGDTITSISP
TH_0076|M.thermoresistible__bu DGSGLDVHTDPAAMADEITRFAGGAQAAGYLQLRNWLDLLYRTEFDRFIA
. : : : .
Mflv_2621|M.gilvum_PYR-GCK GASSVRITLSDGEVRESDAVVGADGVNSVLARTLNGP-------LRTRYV
Mvan_3960|M.vanbaalenii_PYR-1 AAATARVTLSDGRTREADAVVGADGVNSMVARALNGP-------LPSRYV
Mb1290|M.bovis_AF2122/97 DGDSVRVTFERAAAREFDLVIGADGLHSNVRRLVFGP-------EEQFVK
Rv1260|M.tuberculosis_H37Rv DGDSVRVTFERAAAREFDLVIGADGLHSNVRRLVFGP-------EEQFVK
MAV_1408|M.avium_104 RGAAVRVSFERAAPRDFDLVIGADGLHSNVRRLVFGP-------EDEFIE
MMAR_4180|M.marinum_M DGAAVEVTFVRSGTRTFDFLIGADGLHSNVRRKVFGP-------EEQFIK
MUL_4482|M.ulcerans_Agy99 DGAAVEVTFVRSGTRTFDFLIGADGLHSNVRRKVFGP-------EEQFIK
MAB_2678|M.abscessus_ATCC_1997 DGAGVRVAFDRASDRRFDLVIGADGLHSHVRGLVFGP-------ESGYSH
MSMEG_5719|M.smegmatis_MC2_155 DGD---VTFEHHPPRRFDVVVGADGLHSGVRRLVFG--------DNVSEN
TH_0076|M.thermoresistible__bu ANFDSPLSLVSPHLAKLVALGGFRRWEKVMRRFITDERLLRVFTFQALYV
::: : * .. : : .
Mflv_2621|M.gilvum_PYR-GCK GYTAWRGIAAHPLDPELGG--------ETLGPGTQVGHVPLGPDHTYWFA
Mvan_3960|M.vanbaalenii_PYR-1 GYTAWRGVAAYRLDPALAG--------ETMSAGTEVGHVPLGPDHTYWFA
Mb1290|M.bovis_AF2122/97 RLGTHAAIFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARAALAFMD
Rv1260|M.tuberculosis_H37Rv RLGTHAAIFTVPNFLELDYWQTWHYGDSTMAGVYSARNNTEARAALAFMD
MAV_1408|M.avium_104 RLGTHAAIFTVPNFLGLDYWQMWHYGDSTMAGVYSARDNAEARAMLGFMD
MMAR_4180|M.marinum_M RLGTYAAIFTVPNFLELDYWQKWHYGDNTMAGVYSARDNSEARAALGFMD
MUL_4482|M.ulcerans_Agy99 RLGTYAAIFTVPNFLELDYWQKWHYGDNTMAGVYSARDNSEARAALGFMD
MAB_2678|M.abscessus_ATCC_1997 WLGQYLAVASIPNYLDLSDRALMYPQVDKIAGMYSAAQLSDARAFFLFRT
MSMEG_5719|M.smegmatis_MC2_155 FLAGYLSVVSVPKSLARDGEMTSFLKPGHMAAVYTADHLEDARAVFIFRP
TH_0076|M.thermoresistible__bu GVPPQRALAVYAVIAYMDTVNGVYFPAGGVRAVPEALAAAARDAGVEFCY
.: : . :
Mflv_2621|M.gilvum_PYR-GCK TE----------RTAEGGSAPGGEHAYLTAKVADWADPIPRLVATTDPGD
Mvan_3960|M.vanbaalenii_PYR-1 TE----------RTREGSRSAGGEHAYLTAKLAGWADPIPALLASTDPAD
Mb1290|M.bovis_AF2122/97 T-----------ELRIDYRDTEAQFAELQRRMAEDGWVRAQLLHYIAAH-
Rv1260|M.tuberculosis_H37Rv T-----------ELRIDYRDTEAQFAELQRRMAEDGWVRAQLLHYMRSAP
MAV_1408|M.avium_104 A-----------ELRLDYRDTEAQFAELERRMAGEGWVRPQLLEYMRTAP
MMAR_4180|M.marinum_M T-----------ELQIDYRDTEAQFAELERRMIEDGWVRAQLLHYMRSAP
MUL_4482|M.ulcerans_Agy99 T-----------ELQIDYRDTEAQFAELERRMIEDGWVRAQLLHYMRSAP
MAB_2678|M.abscessus_ATCC_1997 PE----------PLDYHHRDVGRQKALLGEVYADVGWELPRMLAEVDATD
MSMEG_5719|M.smegmatis_MC2_155 SR----------PLDYDHRDVERQKAQLRAAFEHIAPEVDRWLDEVPRTP
TH_0076|M.thermoresistible__bu RERVTGLERSGDRVTAVHTDTGRRLAADVVVLTTELPDSYRLLGRRPRRP
. * :
Mflv_2621|M.gilvum_PYR-GCK LLRNDLYDRARAAR-------------------WSDGRAVLIGDAAHPMR
Mvan_3960|M.vanbaalenii_PYR-1 VLRNDLYDRAQPRD-------------------WSRGPAVIVGDAAHPMR
Mb1290|M.bovis_AF2122/97 --------RISIST-------------------KCRRS------------
Rv1260|M.tuberculosis_H37Rv DFYFDEMSQILMDR-------------------WSRGRVALVGDAGYCCS
MAV_1408|M.avium_104 DFYFDEMSQIKMDR-------------------WSRGRVALVGDAGYCCS
MMAR_4180|M.marinum_M DFYFDEMAQIVMDS-------------------WSKGRVALVGDAAYCCS
MUL_4482|M.ulcerans_Agy99 DFYFDEMAQIVMDS-------------------WAKGRVALVGDAAYCCS
MAB_2678|M.abscessus_ATCC_1997 TFYMDSITQLRMDT-------------------WSKGRITLVGDAGYCPG
MSMEG_5719|M.smegmatis_MC2_155 AFYFDAITQLEMTT-------------------WSRGRVTLVGDAGYCPG
TH_0076|M.thermoresistible__bu ARLRPAPSAVVAHVGCRRAEPAPPHHTILFGSAWEQTFRDIIDDGRLMRD
Mflv_2621|M.gilvum_PYR-GCK P------HLGQGGCQGIED---AAILA-RFLELAD--DVPTAFERFEAFR
Mvan_3960|M.vanbaalenii_PYR-1 P------HLGQGGCQGLED---AAILA-RFVGLSP--DLPAAFDRFGAFR
Mb1290|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv P------LSGQGTSVALLG---AYILAGELKAAGD--DYQLGFANYHAEF
MAV_1408|M.avium_104 P------LSGQGTSVALLG---AYILAGELKAAGE--DHEAGFANYHREF
MMAR_4180|M.marinum_M P------LSGQGTSVAVLG---AYILAGELAAAGN--DYQRGFANYHAEF
MUL_4482|M.ulcerans_Agy99 P------LSGQGTSVAVLG---AYILAGELAAAGN--DYQRGFANYHAEF
MAB_2678|M.abscessus_ATCC_1997 P------AVGGSTSLAVVG---AYVLAGEIAAAAG--DHARAYPAYEAAL
MSMEG_5719|M.smegmatis_MC2_155 P------AVGGSTSLAVYG---AYVLAAEMVRAGE--DYPAAFDAYERTM
TH_0076|M.thermoresistible__bu PSLLVSRPTAGDASLAPDGRDLLYILAPAPNTAAGRIDWDLLGDGYAEEM
Mflv_2621|M.gilvum_PYR-GCK KPRVGMLVREAQTLGRIVNVRPAVLSG-------------LAGRATALIP
Mvan_3960|M.vanbaalenii_PYR-1 RRRVRPLVRESAAIGRIVNLRPAFLSG-------------VASRASALIP
Mb1290|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv HGFV--ERNQWLVSDNIPGGAP----------------------------
MAV_1408|M.avium_104 ADYV--QRNQWLVVDNIPGGAP----------------------------
MMAR_4180|M.marinum_M SGFV--ERNQWLVTDNIPGGEP----------------------------
MUL_4482|M.ulcerans_Agy99 SGFG--ERNQWLVTDNIPGGEP----------------------------
MAB_2678|M.abscessus_ATCC_1997 REYV--EVSRKLALTASGTLVPKSRLGLCTLVH---GARILGHLPSSLTR
MSMEG_5719|M.smegmatis_MC2_155 LAPV--VGSRKLARFNAKTVVPASGLGIRALVG---VGQLISVLPVGLTR
TH_0076|M.thermoresistible__bu LNAVSARLPESTVDAEMLHVVNPADWERQGMAAGTPFALAHTFSQTGPFR
Mflv_2621|M.gilvum_PYR-GCK ERMVTAHLAWIAAGSAFVLPTAADLAR----------------
Mvan_3960|M.vanbaalenii_PYR-1 EWAVASHLASIAAGSAFILPTAGDVGG----------------
Mb1290|M.bovis_AF2122/97 -------------------------------------------
Rv1260|M.tuberculosis_H37Rv ----IPQEEFERIVHSITIKDY---------------------
MAV_1408|M.avium_104 ----IPQEVFERIVASITLKDY---------------------
MMAR_4180|M.marinum_M ----IPEEAFERIVNSLELEDYRQG------------------
MUL_4482|M.ulcerans_Agy99 ----IPEEAFERIVNSLELEDYRQG------------------
MAB_2678|M.abscessus_ATCC_1997 SLSRLVAARRINIHDTFALRDYQGLISR---------------
MSMEG_5719|M.smegmatis_MC2_155 SLARLNDKG-VRLYDTMPLPQWPARLNG---------------
TH_0076|M.thermoresistible__bu PGNMVRGVANAVLAGGSTVPGVGIPTALLSGRLAADRITGAAR