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MSDVLVSGASVAGTAAAFWLGRHGHSVTVVERHRGPRPGGQAIDVRGPALGVLERMGLLAAAAKRRTQIR GSSVVDRDGNELSRDTEAAISGPTGGPIEGPDIELLRDDLVELLYGASQWTAEYLFDDTITALDDRGAAV RVSFERAAPRDFDLVIGADGLHSNVRRLVFGPEDEFIERLGTHAAIFTVPNFLGLDYWQMWHYGDSTMAG VYSARDNAEARAMLGFMDAELRLDYRDTEAQFAELERRMAGEGWVRPQLLEYMRTAPDFYFDEMSQIKMD RWSRGRVALVGDAGYCCSPLSGQGTSVALLGAYILAGELKAAGEDHEAGFANYHREFADYVQRNQWLVVD NIPGGAPIPQEVFERIVASITLKDY
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_1408 | - | - | 100% (375) | hypothetical protein MAV_1408 |
| M. avium 104 | MAV_0984 | - | 2e-62 | 42.12% (349) | hypothetical protein MAV_0984 |
| M. avium 104 | MAV_4429 | - | 5e-13 | 28.31% (332) | FAD binding domain-containing protein |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb1290 | - | 1e-117 | 79.23% (260) | hypothetical protein Mb1290 |
| M. gilvum PYR-GCK | Mflv_2621 | - | 2e-13 | 25.84% (329) | monooxygenase, FAD-binding |
| M. tuberculosis H37Rv | Rv1260 | - | 1e-178 | 81.72% (372) | hypothetical protein Rv1260 |
| M. leprae Br4923 | - | - | - | - | - |
| M. abscessus ATCC 19977 | MAB_0649c | - | 2e-77 | 42.21% (353) | putative monooxygenase |
| M. marinum M | MMAR_4180 | - | 1e-164 | 75.00% (372) | oxidoreductase |
| M. smegmatis MC2 155 | MSMEG_3039 | - | 2e-63 | 41.91% (346) | monooxygenase |
| M. thermoresistible (build 8) | - | - | - | - | - |
| M. ulcerans Agy99 | MUL_4482 | - | 1e-163 | 74.46% (372) | hypothetical protein MUL_4482 |
| M. vanbaalenii PYR-1 | Mvan_3960 | - | 2e-18 | 28.53% (326) | monooxygenase, FAD-binding |
CLUSTAL 2.0.9 multiple sequence alignment
Mb1290|M.bovis_AF2122/97 ---MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAIDVRG
Rv1260|M.tuberculosis_H37Rv ---MKTVVVSGASVAGTAAAYWLGRHGYSVTMVERHPGLRPGGQAIDVRG
MMAR_4180|M.marinum_M MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVERHPGLRPGGQAIDVRG
MUL_4482|M.ulcerans_Agy99 MVGVQKVLISGASVAGLTTAYWLEQQGYSVTIVERHPGLRPGGQAIDVRG
MAV_1408|M.avium_104 ---MSDVLVSGASVAGTAAAFWLGRHGHSVTVVERHRGPRPGGQAIDVRG
MAB_0649c|M.abscessus_ATCC_199 -MSR-EILISGGGIAGPALAYWLVQEGHSVTIVERAATVRNGGQAVDFRG
MSMEG_3039|M.smegmatis_MC2_155 -MGQPTVLISGAGVAGTSLAHWLTEYGYRAVVVETAPTLRLGGQTVDLRG
Mflv_2621|M.gilvum_PYR-GCK --MSARISVIGAGISGLAAAVALERAGHHVSVIEQRTDTGAG-SGISLWP
Mvan_3960|M.vanbaalenii_PYR-1 --MPAHTIVIGAGIAGLATAVALRRVGHDVTVIEQRTDLTSG-AGISIWP
: *..::* : * * . *: . ::* * :..
Mb1290|M.bovis_AF2122/97 PALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTES---TPTGGP
Rv1260|M.tuberculosis_H37Rv PALDVLERMGLLAAAQEHKTRIRGASFVDRDGNELFRDTES---TPTGGP
MMAR_4180|M.marinum_M PALTVLDRMGILDAARDRKTGIRGASVVDRDGNELSQDTES---TPTGGP
MUL_4482|M.ulcerans_Agy99 PALTVLDRMGILDAARDRKTGIRGASVVDRDGNELSRDTES---TPTGGP
MAV_1408|M.avium_104 PALGVLERMGLLAAAAKRRTQIRGSSVVDRDGNELSRDTEAAISGPTGGP
MAB_0649c|M.abscessus_ATCC_199 PSIDVLDKMGVLDAVRAQATHMGSLVMVDADGKEIARFPSE----VISG-
MSMEG_3039|M.smegmatis_MC2_155 AGRDVVTRMGLLDEMRARSLDQRGIAWVRGNGRRRAEMPVD----AFDGN
Mflv_2621|M.gilvum_PYR-GCK NALAALDQIGLGDSVRDAGGRVTAGAIRWRDGTWVRRPSVR----RIVDA
Mvan_3960|M.vanbaalenii_PYR-1 NALAALDQIGLGDNVRQAGGRVTAGAIRWRDGTWLRRPSAQ----RIVHA
. .: ::*: . :* . .
Mb1290|M.bovis_AF2122/97 VNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQDDGDSVRVTFERA
Rv1260|M.tuberculosis_H37Rv VNSPDIELLRDDLVELLYGATQPSVEYLFDDSISTLQDDGDSVRVTFERA
MMAR_4180|M.marinum_M IDSPNIELLRDDLIELLYGTIQSTTEFIFDDSIATLQDDGAAVEVTFVRS
MUL_4482|M.ulcerans_Agy99 IDSPNIELLRDDLIELLDGTIQSTTEFIFDDSIATLQDDGAAVEVTFVRS
MAV_1408|M.avium_104 IEGPDIELLRDDLVELLYGASQWTAEYLFDDTITALDDRGAAVRVSFERA
MAB_0649c|M.abscessus_ATCC_199 ----ELEILWGDLARILHEAVREHVVFRFADSITGVRDDGAKVTVSFSRS
MSMEG_3039|M.smegmatis_MC2_155 GMVSALEILRGDLVEVLYNATSARAEYRFGTRITEIDSSGA----TLSDG
Mflv_2621|M.gilvum_PYR-GCK LGEPLVVVRRSRLTDILREALPA-GTVRTGLAATRVSVGASSVRITLSDG
Mvan_3960|M.vanbaalenii_PYR-1 LGEPLVVVRRSALTEILLDALPP-DTVQTGLSATALSIAAATARVTLSDG
: : . * :* : : : . :: .
Mb1290|M.bovis_AF2122/97 AAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHAAIFTVPNFLELDY
Rv1260|M.tuberculosis_H37Rv AAREFDLVIGADGLHSNVRRLVFGPEEQFVKRLGTHAAIFTVPNFLELDY
MMAR_4180|M.marinum_M GTRTFDFLIGADGLHSNVRRKVFGPEEQFIKRLGTYAAIFTVPNFLELDY
MUL_4482|M.ulcerans_Agy99 GTRTFDFLIGADGLHSNVRRKVFGPEEQFIKRLGTYAAIFTVPNFLELDY
MAV_1408|M.avium_104 APRDFDLVIGADGLHSNVRRLVFGPEDEFIERLGTHAAIFTVPNFLGLDY
MAB_0649c|M.abscessus_ATCC_199 APESYDLLIGADGVHSGVRALTFGPEHEFVTQLGQYFTFFAMDNHLGLDH
MSMEG_3039|M.smegmatis_MC2_155 TRVDADLIVGADGPHSSVRRMVFGPEEQYVTLLGGYNAWFTAPDTAGLDG
Mflv_2621|M.gilvum_PYR-GCK EVRESDAVVGADGVNSVLARTLNGP-------LRTRYVGYTAWRGIAAHP
Mvan_3960|M.vanbaalenii_PYR-1 RTREADAVVGADGVNSMVARALNGP-------LPSRYVGYTAWRGVAAYR
* ::**** :* : ** * . ::
Mb1290|M.bovis_AF2122/97 WQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRIDYRDTEAQFAELQR
Rv1260|M.tuberculosis_H37Rv WQTWHYGDSTMAGVYSARNNTEARAALAFMDTELRIDYRDTEAQFAELQR
MMAR_4180|M.marinum_M WQKWHYGDNTMAGVYSARDNSEARAALGFMDTELQIDYRDTEAQFAELER
MUL_4482|M.ulcerans_Agy99 WQKWHYGDNTMAGVYSARDNSEARAALGFMDTELQIDYRDTEAQFAELER
MAV_1408|M.avium_104 WQMWHYGDSTMAGVYSARDNAEARAMLGFMDAELRLDYRDTEAQFAELER
MAB_0649c|M.abscessus_ATCC_199 QTVGFREGTRGVGIQATAPDAPARGSLSFSDDHLEFDYRDVEGNKKLFSE
MSMEG_3039|M.smegmatis_MC2_155 WYLMYQVPGLNASMRPSHDPALCKAGLAFRSGPVDYDRRDPATQLALLNT
Mflv_2621|M.gilvum_PYR-GCK LDPELGGETLGPGTQVGHVPLGPDHTYWFATERTAEGGSAPGGEHAYLTA
Mvan_3960|M.vanbaalenii_PYR-1 LDPALAGETMSAGTEVGHVPLGPDHTYWFATERTREGSRSAGGEHAYLTA
. * . : :
Mb1290|M.bovis_AF2122/97 RMAEDGWVRAQLLHYIAAH---------RISISTKCRRS-----------
Rv1260|M.tuberculosis_H37Rv RMAEDGWVRAQLLHYMRSAPDFYFDEMSQILMDRWSRGRVALVGDAGYCC
MMAR_4180|M.marinum_M RMIEDGWVRAQLLHYMRSAPDFYFDEMAQIVMDSWSKGRVALVGDAAYCC
MUL_4482|M.ulcerans_Agy99 RMIEDGWVRAQLLHYMRSAPDFYFDEMAQIVMDSWAKGRVALVGDAAYCC
MAV_1408|M.avium_104 RMAGEGWVRPQLLEYMRTAPDFYFDEMSQIKMDRWSRGRVALVGDAGYCC
MAB_0649c|M.abscessus_ATCC_199 RFTGFGWETPAVLRALSVTAEPYFDSLCQVHLDTYSRGRVCLLGDAAWCA
MSMEG_3039|M.smegmatis_MC2_155 HFAGAGWHCADLLAAAAVADDFYFDAFLQVHMPTLSRGPVTLVGDAGYCA
Mflv_2621|M.gilvum_PYR-GCK KVADWADPIPRLVATTDPGDLLRNDLYDRARAARWSDGRAVLIGDAAHPM
Mvan_3960|M.vanbaalenii_PYR-1 KLAGWADPIPALLASTDPADVLRNDLYDRAQPRDWSRGPAVIVGDAAHPM
:. . . :: : .
Mb1290|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv SPLSGQGTSVALLGAYILAGELK----AAGDDYQLGFANYHAEFHGFVER
MMAR_4180|M.marinum_M SPLSGQGTSVAVLGAYILAGELA----AAGNDYQRGFANYHAEFSGFVER
MUL_4482|M.ulcerans_Agy99 SPLSGQGTSVAVLGAYILAGELA----AAGNDYQRGFANYHAEFSGFGER
MAV_1408|M.avium_104 SPLSGQGTSVALLGAYILAGELK----AAGEDHEAGFANYHREFADYVQR
MAB_0649c|M.abscessus_ATCC_199 SPRSGMGTSLAIVGAYVLAHELR----SAQGDFSIAFARFHTLMAPYAAR
MSMEG_3039|M.smegmatis_MC2_155 SPLSGMGTSLALVGAYVLAGELGPADMFAHAKLGLALSRYESTMRPYIER
Mflv_2621|M.gilvum_PYR-GCK RPHLGQGGCQGIEDAAILARFLE-----LADDVPTAFERFEAFRKPRVGM
Mvan_3960|M.vanbaalenii_PYR-1 RPHLGQGGCQGLEDAAILARFVG-----LSPDLPAAFDRFGAFRRRRVRP
Mb1290|M.bovis_AF2122/97 --------------------------------------------------
Rv1260|M.tuberculosis_H37Rv NQWLVSDN-----------------------IPGGAPIPQEEFERIVHSI
MMAR_4180|M.marinum_M NQWLVTDN-----------------------IPGGEPIPEEAFERIVNSL
MUL_4482|M.ulcerans_Agy99 NQWLVTDN-----------------------IPGGEPIPEEAFERIVNSL
MAV_1408|M.avium_104 NQWLVVDN-----------------------IPGGAPIPQEVFERIVASI
MAB_0649c|M.abscessus_ATCC_199 CQRLALDALKIGEADSPWATGLRRLGLWSLRLPGIRQLVARQALKVGRSF
MSMEG_3039|M.smegmatis_MC2_155 CQDLPTGIDGYLPKSALDITIYTQVMKWMQRWP-IRSYAARKWFTTADAI
Mflv_2621|M.gilvum_PYR-GCK LVREAQTLGRIVNVRPAVLSG--LAGRATALIPERMVTAHLAWIAAGSAF
Mvan_3960|M.vanbaalenii_PYR-1 LVRESAAIGRIVNLRPAFLSG--VASRASALIPEWAVASHLASIAAGSAF
Mb1290|M.bovis_AF2122/97 ------------
Rv1260|M.tuberculosis_H37Rv TIKDY-------
MMAR_4180|M.marinum_M ELEDYRQG----
MUL_4482|M.ulcerans_Agy99 ELEDYRQG----
MAV_1408|M.avium_104 TLKDY-------
MAB_0649c|M.abscessus_ATCC_199 ALPAYD------
MSMEG_3039|M.smegmatis_MC2_155 QLPSYPAAQNKR
Mflv_2621|M.gilvum_PYR-GCK VLPTAADLAR--
Mvan_3960|M.vanbaalenii_PYR-1 ILPTAGDVGG--