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VLDPELLRTFLTVERAGGFTAAGRILGLRQSTVSGHIARLEQSVGRELFRRDTRNLAPTADGAAMVGFAR SILDAQAQADRFFASSELTGLIRLGASDDLVARELPDVLVEFQNSHPGVDLELVVGLSEYLKTRMTAGEL DLMVAKRLPGETHGELLWRDKLVWAGRPNTHHVRDPVPVVTYPPPSLTRHAALRALEREGRTWRIACVSD SQLGLRAAALAGMGVIAHAESLLPSGLVKVSDDSLPDLGELEFVLLRRRSVLSEPEQALCDAIVASTHRL HGDFGFTKGAGAGH
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_4730 | - | - | 100% (294) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3179c | - | 1e-14 | 27.51% (269) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0161 | - | 7e-14 | 35.21% (142) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 4e-07 | 27.08% (144) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 5e-12 | 28.23% (248) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 4e-07 | 27.08% (144) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-14 | 35.71% (154) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_4902 | - | 2e-09 | 27.32% (183) | putative regulatory protein |
| M. avium 104 | MAV_0094 | - | 4e-13 | 26.06% (284) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_2544 | - | 3e-16 | 30.18% (285) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_0172 | - | 1e-07 | 27.63% (152) | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 2e-09 | 30.43% (138) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 1e-10 | 27.34% (256) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0094|M.avium_104 ------MGQVLDIAPLRSLVAVADCGGFHRAAAALHLSQSAVSQHLRRIE
MSMEG_2544|M.smegmatis_MC2_155 ------MGQVLDIAPLRSLVAVADCGGFHRAAAVLHLTQSAVSQHVRRLE
Mflv_3565|M.gilvum_PYR-GCK ----------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQIRRLE
Mvan_3362|M.vanbaalenii_PYR-1 ----------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQIRRLE
MLBr_02041|M.leprae_Br4923 ---MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALE
MUL_2998|M.ulcerans_Agy99 MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQALAALE
Mb0384|M.bovis_AF2122/97 ----------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALR
Rv0377|M.tuberculosis_H37Rv ----------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMHVAALR
TH_0172|M.thermoresistible__bu ----------MTPAQLRAFSAVVRLGSVRAAAQELGMSDAGISMHIAQLR
MAB_4730|M.abscessus_ATCC_1997 ---------MLDPELLRTFLTVERAGGFTAAGRILGLRQSTVSGHIARLE
MMAR_4902|M.marinum_M ---------MIDPHRLRILRAVVAEGSIGGAAAALGCTPSAVSQHIAVLQ
*. :: . *. . :* : :.
MAV_0094|M.avium_104 AVVGEPIVQRSGRGVVFTEVGQKALRHARTILAAHD---TALDDLGATEN
MSMEG_2544|M.smegmatis_MC2_155 GVVGGPIVQRSGRGMAFTELGHRVVAHARRILAAHD---AALADLGAAEE
Mflv_3565|M.gilvum_PYR-GCK RSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDVAGLLR
Mvan_3362|M.vanbaalenii_PYR-1 RQVGQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDVANLVR
MLBr_02041|M.leprae_Br4923 SGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLR
MUL_2998|M.ulcerans_Agy99 AGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGEADPLN
Mb0384|M.bovis_AF2122/97 KELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHGRR
Rv0377|M.tuberculosis_H37Rv KELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEAAHGRR
TH_0172|M.thermoresistible__bu KELDDPLFHRTKNGLSFTPGGLRLASRAVDILGLQRQTAIEVTEAAHGRR
MAB_4730|M.abscessus_ATCC_1997 QSVGRELFRRDTRNLAPTADGAAMVGFARSILDAQAQADRFFAS--SELT
MMAR_4902|M.marinum_M REIGLTLVEKVGRGIAPTDAGATLAAESAAVFDGLSRLDGLVADLRHGRA
:. :. : : * * : .
MAV_0094|M.avium_104 KVLTIGATEHGADVMLAGLSGALRDRLPDLRVRFRLDRNVSLADSIDRGL
MSMEG_2544|M.smegmatis_MC2_155 KTLLIGATEHGADVMLPGLNDALAECLPDWRVRFRLDRNVALADAIEHGT
Mflv_3565|M.gilvum_PYR-GCK GSVAIGTV-TLHPMNVAHLIAEFHADHPDVEITLGTATSDVLIAELGDGR
Mvan_3362|M.vanbaalenii_PYR-1 GAVAIGTV-TLHPVDVARLMADFHAEHPGVEITLGTDTSDVLLAKLEDGR
MLBr_02041|M.leprae_Br4923 GGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTALREGA
MUL_2998|M.ulcerans_Agy99 GSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTALREGS
Mb0384|M.bovis_AF2122/97 -LLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFRELICSRA
Rv0377|M.tuberculosis_H37Rv -LLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFRELICSRA
TH_0172|M.thermoresistible__bu -LLRIAASHAFAEHAAPGLIDLFSSRADDLSVELTVEPVSRFRDLLESRA
MAB_4730|M.abscessus_ATCC_1997 GLIRLGASDDLVARELPDVLVEFQNSHPGVDLELVVGLSEYLKTRMTAGE
MMAR_4902|M.marinum_M GTLRVSYFASAGAAWMPAVIATISSEYPAVRLDLRLVELADADDAAPDVE
: .. . : : : .
MAV_0094|M.avium_104 VDVAIMLDGAGL-------------DRANASGLVRLQWVSAR-TLTIAPK
MSMEG_2544|M.smegmatis_MC2_155 VDVAVMLDGSGW-------------DRVNASGMVPLKWISAR-NFGCD-G
Mflv_3565|M.gilvum_PYR-GCK LDLAIVSIAVDED--LPGLEVAVITDEAVEAAVADGHPLAHRRSLSLEQL
Mvan_3362|M.vanbaalenii_PYR-1 LDAAIVSIGADED--PAGLEYEVITDEALEAAVTAQHRLARRKSLSLKQL
MLBr_02041|M.leprae_Br4923 LDAAMIALPVET----AGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTAL
MUL_2998|M.ulcerans_Agy99 LDTALIALPADY----GGLTEIPIYEEDFVLALPPGHPMADRHGVPVAAL
Mb0384|M.bovis_AF2122/97 VDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPMPALLR
Rv0377|M.tuberculosis_H37Rv VDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPMPALLR
TH_0172|M.thermoresistible__bu VDVTLGPAVRE---PGPAIVVRPFLNYQIIAVTSPSNPLAAATPTIAQLR
MAB_4730|M.abscessus_ATCC_1997 LDLMVAKRLPG---------------ETHGELLWRDKLVWAGRPNTHHVR
MMAR_4902|M.marinum_M INVAGMPGTELSN-----YDTAALVTEDYVVVVGAGDSLAERDSVTLREL
:: :
MAV_0094|M.avium_104 DPLPLVIFSEPC-TLREPAFAILDSHRIDYEIAAECGDLSGLYAAVRSG-
MSMEG_2544|M.smegmatis_MC2_155 EPLPVVVYSEPC-TLREPAFAALEKLEVDYQIVAECADLSGLIAAVRSG-
Mflv_3565|M.gilvum_PYR-GCK SRHPLISLPAGT-GLRTRLDTACAAAGLRPRIAFEATSPAELAELARHG-
Mvan_3362|M.vanbaalenii_PYR-1 CEYPVISLPAGT-GLRSRLDDACAAAGLRPRIAFEATSPLELADLARHG-
MLBr_02041|M.leprae_Br4923 AQLPLLLLDEGH-CLRDQTLDICRKSGVQAELANTRAASLATAVQCVTGG
MUL_2998|M.ulcerans_Agy99 SELPLLLLDEGH-CLRDQALDVCQNAGVRAEHADTRADSLATAVQCVNGG
Mb0384|M.bovis_AF2122/97 HQQWMLGPSAGS-VDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRVG-
Rv0377|M.tuberculosis_H37Rv HQQWMLGPSAGS-VDGEIATMLRGLAIPESQQRIFQSDAAALEEVMRVG-
TH_0172|M.thermoresistible__bu AQSWMLGPSAGG-IDGDVAAMLRRLEIPEAAQRIFQSDSAAQEEVQRIG-
MAB_4730|M.abscessus_ATCC_1997 DPVPVVTYPPPS-LTRHAALRALEREGRTWRIACVSDSQLGLRAAALAG-
MMAR_4902|M.marinum_M AGEPWIDNDVARGNCRENLLRACTAAGFTPCFRVETHDYVTAVRFVAAG-
: *
MAV_0094|M.avium_104 LGVALLPMIGKFPDGLGPAEGLPPANNASILVRGRTGIDPALLSTVDTAV
MSMEG_2544|M.smegmatis_MC2_155 LGIALLPMIGRLPDGLTVADTMPEANRASVFVRGRAGVDSGLLATVDTAV
Mflv_3565|M.gilvum_PYR-GCK LGVAILPQSMARGGSGLHALRLAPELRGRLVWAWRADGANPAARVLGERA
Mvan_3362|M.vanbaalenii_PYR-1 LGVAILPRSMARGSAGLHPLRLSPELRGRLVWAWRTDISGPAARLLNARA
MLBr_02041|M.leprae_Br4923 LGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASYRQ
MUL_2998|M.ulcerans_Agy99 LGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRRIGLVYRASSGRDEAYRQ
Mb0384|M.bovis_AF2122/97 -GATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSE
Rv0377|M.tuberculosis_H37Rv -GATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQPAVSE
TH_0172|M.thermoresistible__bu -GVTLSIGFAVAKDLAAGRLARIKG--VQATAEWCVSTLSSAARQPAASE
MAB_4730|M.abscessus_ATCC_1997 MGVIAHAESLLPSGLVKVSDDSLPDLGELEFVLLRRRSVLSEPEQALCDA
MMAR_4902|M.marinum_M VGLTVVPRLALIDLPAGVRTVAISEPTPRRTIVVRRHHRARN-NVVAGRV
*
MAV_0094|M.avium_104 RDLLATAT---------------------------
MSMEG_2544|M.smegmatis_MC2_155 RELLNDDRPSGTMVAKTSVKVSA------------
Mflv_3565|M.gilvum_PYR-GCK RAMAVSPGSGAPAVVPGA-----------------
Mvan_3362|M.vanbaalenii_PYR-1 RAMIAATG--TPAVIPGA-----------------
MLBr_02041|M.leprae_Br4923 IAKIIGELISTEHHVRLVA----------------
MUL_2998|M.ulcerans_Agy99 LAAIMGESISNEQQVRLVN----------------
Mb0384|M.bovis_AF2122/97 LVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv LVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
TH_0172|M.thermoresistible__bu LVRFITTPRCTQAMIRGTSEGVTRFRPKVHVTLWS
MAB_4730|M.abscessus_ATCC_1997 IVASTHRLHGDFGFTKGAGAGH-------------
MMAR_4902|M.marinum_M LELIHQQAVRTHGPAVGALA---------------