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IDPHRLRILRAVVAEGSIGGAAAALGCTPSAVSQHIAVLQREIGLTLVEKVGRGIAPTDAGATLAAESAA VFDGLSRLDGLVADLRHGRAGTLRVSYFASAGAAWMPAVIATISSEYPAVRLDLRLVELADADDAAPDVE INVAGMPGTELSNYDTAALVTEDYVVVVGAGDSLAERDSVTLRELAGEPWIDNDVARGNCRENLLRACTA AGFTPCFRVETHDYVTAVRFVAAGVGLTVVPRLALIDLPAGVRTVAISEPTPRRTIVVRRHHRARNNVVA GRVLELIHQQAVRTHGPAVGALA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. marinum M | MMAR_4902 | - | - | 100% (304) | putative regulatory protein |
| M. marinum M | MMAR_4117 | - | 6e-23 | 27.89% (294) | putative regulatory protein |
| M. marinum M | MMAR_4157 | - | 4e-14 | 26.98% (278) | LuxR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 6e-12 | 29.68% (283) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_1346 | - | 5e-19 | 30.83% (240) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 6e-12 | 29.68% (283) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 8e-13 | 26.59% (252) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_0678 | - | 2e-23 | 30.43% (322) | LysR family transcriptional regulator |
| M. avium 104 | MAV_2838 | - | 2e-15 | 28.00% (300) | hydrogen peroxide-inducible genes activator |
| M. smegmatis MC2 155 | MSMEG_1895 | - | 1e-19 | 29.00% (269) | HTH-type transcriptional regulator AlsR |
| M. thermoresistible (build 8) | TH_3504 | - | 1e-11 | 28.24% (262) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_3983 | - | 1e-22 | 27.89% (294) | putative regulatory protein |
| M. vanbaalenii PYR-1 | Mvan_3401 | - | 2e-14 | 29.88% (251) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02041|M.leprae_Br4923 MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGL
MAV_2838|M.avium_104 MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQALAALEAGL
Mflv_1346|M.gilvum_PYR-GCK -------MKLRHLRYFRAVAEELHFGRAAQRLLIAQPPLSQQIRQLEREV
MSMEG_1895|M.smegmatis_MC2_155 -------MELRHLRYFRAVGEELHFGRAAERLHMAQPPLSQQIRQLEREL
Mb2303c|M.bovis_AF2122/97 MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
Rv2282c|M.tuberculosis_H37Rv MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRRLASMEAQI
MMAR_4902|M.marinum_M ------MIDPHRLRILRAVVAEGSIGGAAAALGCTPSAVSQHIAVLQREI
MAB_0678|M.abscessus_ATCC_1997 -------MDVRRLRILREFADRGTVGEVADAMSLTPSAVSQQLKVLTREA
MUL_3983|M.ulcerans_Agy99 ------MLNLQRVVVLHELQRRGTLAAVAKALSYSPSAVSQQLAQLEREC
Mvan_3401|M.vanbaalenii_PYR-1 -------MDTRRLELLLALSRLGSMRAVADAHHLTTSTVSQQIAALARDT
TH_3504|M.thermoresistible__bu --VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSAVRALENDV
. : . . .* .:* : :
MLBr_02041|M.leprae_Br4923 GVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGESDPLRGGM
MAV_2838|M.avium_104 GTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGSADPLRAGM
Mflv_1346|M.gilvum_PYR-GCK GADLLRRTTRSVELTEAGRAFLERTVRILDAVDDAVDQARRIGTGAEGRL
MSMEG_1895|M.smegmatis_MC2_155 GCTLLTRTTRSVELTPAGHTYLRRAVEILDAVDAANTEAQRIASGIQGRI
Mb2303c|M.bovis_AF2122/97 GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
Rv2282c|M.tuberculosis_H37Rv GVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSLRTEGRQRI
MMAR_4902|M.marinum_M GLTLVEKVGRGIAPTDAGATLAAESAAVFDGLSRLDGLVADLRHGRAGTL
MAB_0678|M.abscessus_ATCC_1997 GVPLLRQDGRGIALTEAGHALVLRADEVIAAVDRADEEMVAYREGTQPVV
MUL_3983|M.ulcerans_Agy99 GMALIEPVGRGVRLTDAGEALVEHTRLAIATLERAEALLAASQGRVAGRL
Mvan_3401|M.vanbaalenii_PYR-1 GAALIEPEGRRVRLTPAGKRLADHAVTILAAVDRARLDLDPDAEP-AGTV
TH_3504|M.thermoresistible__bu GADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQTEAAAQAHY
* * * * * .
MLBr_02041|M.leprae_Br4923 RLGLIPTVAPYVLPTMLTGLTHRLP----TLTLRVV-EDQTEHLLTALRE
MAV_2838|M.avium_104 RLGLIPTVAPYVLPTVLAGIAERRP----GLTLRVT-EDQTERLLAVLRE
Mflv_1346|M.gilvum_PYR-GCK VVGCVGSATYSLLPRLVRELRAALP----AVDLRVRGEMLAPEQLAALHA
MSMEG_1895|M.smegmatis_MC2_155 AIGCVGSATYSLLPQLVRALGESLP----GIEVTVRGEMLAPAQIEALLS
Mb2303c|M.bovis_AF2122/97 RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
Rv2282c|M.tuberculosis_H37Rv RVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSEHAIAAVRD
MMAR_4902|M.marinum_M RVSYFASAGAAWMPAVIATISSEYP----AVRLDLRLVELADADDAAP--
MAB_0678|M.abscessus_ATCC_1997 RVASFPSGAGVLLPRVVAAVAEAVD----IRPSDEDVTYGEAPGLLTEYD
MUL_3983|M.ulcerans_Agy99 RVAAFRTLLLSLPPRVLDALARDYPDLR-VEVAQREADEATSGLLAGTFD
Mvan_3401|M.vanbaalenii_PYR-1 RVGGFATGIRVSLLPIVADLAVRYP-EVDVVISEYEPVEAFKLLTADDLD
TH_3504|M.thermoresistible__bu VIGHTPALSGAEAYALIEPAVTAYP-----STSFTLRQLYPDALTDAVFD
: : :
MLBr_02041|M.leprae_Br4923 GALDAAMIALP-VETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALA
MAV_2838|M.avium_104 GALDAALIALP-AETAGVTAIPIYDEDFVLALPPGHPLAGKRRVPATALA
Mflv_1346|M.gilvum_PYR-GCK KDIDLALMRPP-VDDPALTAVSLRRDRLLVALPAGHRCADRDEVSLADLR
MSMEG_1895|M.smegmatis_MC2_155 GGIDLALLRPP-VRQEAVLTHTVRRDGLVVALPADHALAIRDAVTVADLR
Mb2303c|M.bovis_AF2122/97 GIADLGFIENP-CPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSAREL
Rv2282c|M.tuberculosis_H37Rv GIADLGFIENP-CPPTGLGSVVVARDELVVVVPPGHKWARRSRVVSAREL
MMAR_4902|M.marinum_M -DVEINVAGMPGTELSNYDTAALVTEDYVVVVGAGDSLAERDSVTLRELA
MAB_0678|M.abscessus_ATCC_1997 LVITHRDERAAALQSPRVWSTTLLREPIDLLVHRDHPLAACDSVTPAELA
MUL_3983|M.ulcerans_Agy99 VVLGEEYPGGPLPPSPSLDRVDLRTDELFLAMPRIGPWS--DATTLSDLE
Mvan_3401|M.vanbaalenii_PYR-1 LALTYDYNLAPASPGADLDAVPLWSIGWGLGVPSG----TAADRGLMTFA
TH_3504|M.thermoresistible__bu GTVQLG-LRRGVVPTPELATAVIGYHRVRVAFVDSHPLAARESVDITELA
: : .
MLBr_02041|M.leprae_Br4923 QLPLLLLDEG--HCLRDQTLDICRKSGVQAELAN--TRAASLATAVQCVT
MAV_2838|M.avium_104 DLPLLLLDEG--HCLRDQALDVCHKAGVRAELAN--TRAASLATAVQCVT
Mflv_1346|M.gilvum_PYR-GCK DEDFISHAGGGRSRMSALLAALCADAGFSPRIR---DEVDETSTLVTLVA
MSMEG_1895|M.smegmatis_MC2_155 DEDFVVHTGHGRSVMSNLVATVCADAGFLPRIR---QEVSETSTLVTLVA
Mb2303c|M.bovis_AF2122/97 AQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVL
Rv2282c|M.tuberculosis_H37Rv AQTPLVTREPNSGIRDSLTAALRDTLGEDMQQAPPVLELSSAAAVRAAVL
MMAR_4902|M.marinum_M GEPWIDNDVARGNCRENLLR-ACTAAGFTPCFR---VETHDYVTAVRFVA
MAB_0678|M.abscessus_ATCC_1997 DETWISVPEG--FPVDDVLVSLGVSTGIIPRVR---FRFKDFQIVEDMVA
MUL_3983|M.ulcerans_Agy99 YASWALDPEP--TVPGRWARSVCRAAGFEPDVR---FDGVDLLVHLQMVQ
Mvan_3401|M.vanbaalenii_PYR-1 DSTWIVNSRN--TADETAVRTLASLAGFTPTIA---HQIDSLDLVEDLIV
TH_3504|M.thermoresistible__bu REQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVS--RVQGAATVAAPLT
* :
MLBr_02041|M.leprae_Br4923 GGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRSASGRSASY
MAV_2838|M.avium_104 GGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLVFRSSSGRDDSY
Mflv_1346|M.gilvum_PYR-GCK GGLGVALVPEPTAALEIGG-----VTYRPLAAKAGATIELLAVYRSADAS
MSMEG_1895|M.smegmatis_MC2_155 AGLGVAIVPDPTTALDIAG-----VRYVPLRPTD-LGVDLVAAH--TGDS
Mb2303c|M.bovis_AF2122/97 AGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGR--TPPA
Rv2282c|M.tuberculosis_H37Rv AGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAIWVGGR--TPPA
MMAR_4902|M.marinum_M AGVGLTVVPRLALIDLPAG--VRTVAISEPTPRRTIVVRRHHRARNNVVA
MAB_0678|M.abscessus_ATCC_1997 HGHGVALMPRYASRSPRVAR----VVIREVRAARLYEVLARPGARHRPAI
MUL_3983|M.ulcerans_Agy99 AGLAVAILPALLGQDRMRG---VRLAPLPASPKRQLFTLTRTSRTAHPAV
Mvan_3401|M.vanbaalenii_PYR-1 AGFGVGLLPLGRPTSPGVT----VLPLQNPDVTLTAYAVTRRGRSAWSPL
TH_3504|M.thermoresistible__bu TG-GIAFVTAAAGPTMNGR-----VQVVDLTPPLLVPVQALWQR---HTL
* . :.
MLBr_02041|M.leprae_Br4923 RQIAKIIGELISTEHHVRLVA----------
MAV_2838|M.avium_104 RELAGLIGELISSQHQVRLVK----------
Mflv_1346|M.gilvum_PYR-GCK PLTAKVVDVLRATV-----------------
MSMEG_1895|M.smegmatis_MC2_155 PLITNVLRVLRTLTEGPKSPTQAHPGT----
Mb2303c|M.bovis_AF2122/97 GAIRDLLSHITSRST----------------
Rv2282c|M.tuberculosis_H37Rv GAIRDLLSHITSRST----------------
MMAR_4902|M.marinum_M GRVLELIHQQAVRTHGPAVGALA--------
MAB_0678|M.abscessus_ATCC_1997 AATIQGLRDAAAVLESR--------------
MUL_3983|M.ulcerans_Agy99 VAFRTALAEGFDAQHQYD-------------
Mvan_3401|M.vanbaalenii_PYR-1 RAILDRMRPPAGLLQHPTWPRPEAAVANQSA
TH_3504|M.thermoresistible__bu SAIRDRILEGLG-------------------
: