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GQVLDIAPLRSLVAVADCGGFHRAAAALHLSQSAVSQHLRRIEAVVGEPIVQRSGRGVVFTEVGQKALRH ARTILAAHDTALDDLGATENKVLTIGATEHGADVMLAGLSGALRDRLPDLRVRFRLDRNVSLADSIDRGL VDVAIMLDGAGLDRANASGLVRLQWVSARTLTIAPKDPLPLVIFSEPCTLREPAFAILDSHRIDYEIAAE CGDLSGLYAAVRSGLGVALLPMIGKFPDGLGPAEGLPPANNASILVRGRTGIDPALLSTVDTAVRDLLAT AT*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. avium 104 | MAV_0094 | - | - | 100% (283) | transcriptional regulator, LysR family protein |
| M. avium 104 | MAV_2838 | - | 3e-15 | 28.33% (240) | hydrogen peroxide-inducible genes activator |
| M. avium 104 | MAV_4979 | - | 3e-13 | 24.07% (241) | transcriptional regulator, LysR family protein, putative |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 7e-09 | 28.99% (207) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 5e-14 | 30.24% (248) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 7e-09 | 28.99% (207) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 3e-13 | 29.46% (241) | putative LysR-family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3179c | - | 5e-90 | 58.18% (275) | LysR family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 7e-15 | 27.50% (280) | hydrogen peroxide-inducible genes activator, OxyR |
| M. smegmatis MC2 155 | MSMEG_2544 | - | 1e-111 | 71.33% (279) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 2e-11 | 40.70% (86) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 2e-14 | 27.86% (280) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 1e-15 | 29.69% (293) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0094|M.avium_104 -----------MGQVLDIAPLRSLVAVADCGGFHRAAAALHLSQSAVSQH
MSMEG_2544|M.smegmatis_MC2_155 -----------MGQVLDIAPLRSLVAVADCGGFHRAAAVLHLTQSAVSQH
MAB_3179c|M.abscessus_ATCC_199 ----------MASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQH
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MLBr_02041|M.leprae_Br4923 --------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQA
Mflv_3565|M.gilvum_PYR-GCK ---------------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQ
Mvan_3362|M.vanbaalenii_PYR-1 ---------------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQ
Mb0384|M.bovis_AF2122/97 ---------------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMH
Rv0377|M.tuberculosis_H37Rv ---------------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMH
TH_3504|M.thermoresistible__bu ----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSA
* *:. . ** : : :*
MAV_0094|M.avium_104 LRRIEAVVGEPIVQRSGRGVVFTEVGQKALRHARTILAAHD---TALDDL
MSMEG_2544|M.smegmatis_MC2_155 VRRLEGVVGGPIVQRSGRGMAFTELGHRVVAHARRILAAHD---AALADL
MAB_3179c|M.abscessus_ATCC_199 VRKLETAIGEPVVRRYGRGVVFTDRGARLLVHARRILAAHD---AAVDDL
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MLBr_02041|M.leprae_Br4923 LAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGE
Mflv_3565|M.gilvum_PYR-GCK IRRLERSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDV
Mvan_3362|M.vanbaalenii_PYR-1 IRRLERQVGQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDV
Mb0384|M.bovis_AF2122/97 VAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEA
Rv0377|M.tuberculosis_H37Rv VAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEA
TH_3504|M.thermoresistible__bu VRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQT
: :. :. :. * : .* * .. :
MAV_0094|M.avium_104 GATENKVLTIGATEHGADVMLAGLSGALRDRLPDLRVRFRLDRNVSLADS
MSMEG_2544|M.smegmatis_MC2_155 GAAEEKTLLIGATEHGADVMLPGLNDALAECLPDWRVRFRLDRNVALADA
MAB_3179c|M.abscessus_ATCC_199 VAGQERALVLGVTEHGADLILPSITSALRSHLPDWSVRVRFDRNLYLAES
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTA
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTA
MLBr_02041|M.leprae_Br4923 SDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTA
Mflv_3565|M.gilvum_PYR-GCK AGLLRGSVAIGTV-TLHPMNVAHLIAEFHADHPDVEITLGTATSDVLIAE
Mvan_3362|M.vanbaalenii_PYR-1 ANLVRGAVAIGTV-TLHPVDVARLMADFHAEHPGVEITLGTDTSDVLLAK
Mb0384|M.bovis_AF2122/97 AHG-RRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFREL
Rv0377|M.tuberculosis_H37Rv AHG-RRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFREL
TH_3504|M.thermoresistible__bu EAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTLRQLYPDALTDA
. :. : . . :
MAV_0094|M.avium_104 IDRGLVDVAIMLDGAGLD--------------RANASGLVRLQWVSARTL
MSMEG_2544|M.smegmatis_MC2_155 IEHGTVDVAVMLDGSGWD--------------RVNASGMVPLKWISARNF
MAB_3179c|M.abscessus_ATCC_199 VDRGIMDLAVILDGSGLD--------------RANAVGTVPLQWVAARGY
MMAR_2756|M.marinum_M LREGSLDTALIALPADYG----GLTEIPIYEEDFVLALPPGHPMADRHGV
MUL_2998|M.ulcerans_Agy99 LREGSLDTALIALPADYG----GLTEIPIYEEDFVLALPPGHPMADRHGV
MLBr_02041|M.leprae_Br4923 LREGALDAAMIALPVETA----GIAEIPIYDEDFVLALPPGHPLSGKRRV
Mflv_3565|M.gilvum_PYR-GCK LGDGRLDLAIVSIAVDEDLP--GLEVAVITDEAVEAAVADGHPLAHRRSL
Mvan_3362|M.vanbaalenii_PYR-1 LEDGRLDAAIVSIGADEDPA--GLEYEVITDEALEAAVTAQHRLARRKSL
Mb0384|M.bovis_AF2122/97 ICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPM
Rv0377|M.tuberculosis_H37Rv ICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAPNSPLAAGIPM
TH_3504|M.thermoresistible__bu VFDGTVQLGLRRGVVPTP----ELATAVIGYHRVRVAFVDSHPLAARESV
: :: .:
MAV_0094|M.avium_104 TIAPKDPLPLVIFSEP--CTLREPAFAILDSHRIDYEIAAECGDLSGLYA
MSMEG_2544|M.smegmatis_MC2_155 GCD-GEPLPVVVYSEP--CTLREPAFAALEKLEVDYQIVAECADLSGLIA
MAB_3179c|M.abscessus_ATCC_199 KPNPIEPLRVMTFTEP--CTLRAPMFSALHTLGNQYQIVGESPDLSGLYA
MMAR_2756|M.marinum_M PVAALSELPLLLLDEG--HCLRDQALDVCQNAGVRAELADTRAASLATAV
MUL_2998|M.ulcerans_Agy99 PVAALSELPLLLLDEG--HCLRDQALDVCQNAGVRAEHADTRADSLATAV
MLBr_02041|M.leprae_Br4923 PTTALAQLPLLLLDEG--HCLRDQTLDICRKSGVQAELANTRAASLATAV
Mflv_3565|M.gilvum_PYR-GCK SLEQLSRHPLISLPAG--TGLRTRLDTACAAAGLRPRIAFEATSPAELAE
Mvan_3362|M.vanbaalenii_PYR-1 SLKQLCEYPVISLPAG--TGLRSRLDDACAAAGLRPRIAFEATSPLELAD
Mb0384|M.bovis_AF2122/97 PALLRHQQWMLGPSAG--SVDGEIATMLRGLAIPESQQRIFQSDAAALEE
Rv0377|M.tuberculosis_H37Rv PALLRHQQWMLGPSAG--SVDGEIATMLRGLAIPESQQRIFQSDAAALEE
TH_3504|M.thermoresistible__bu DITELAREQVALWAPPGTSYYSDFLMGACRRAGFEPDYVVSRVQGAATVA
:
MAV_0094|M.avium_104 AVRSG-----LGVALLPMIGKFPDGLGPAEGLPPANNASILVRGRTGIDP
MSMEG_2544|M.smegmatis_MC2_155 AVRSG-----LGIALLPMIGRLPDGLTVADTMPEANRASVFVRGRAGVDS
MAB_3179c|M.abscessus_ATCC_199 GLRSG-----LGMALLPIIGWLPDGIAPVDAMPAANLATLSVVGRRGLDP
MMAR_2756|M.marinum_M QCVNGG----LGVTLIPQSAVSVEAARSRVGLAHFAAPTPGRRIGLVYRA
MUL_2998|M.ulcerans_Agy99 QCVNGG----LGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRRIGLVYRA
MLBr_02041|M.leprae_Br4923 QCVTGG----LGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFRS
Mflv_3565|M.gilvum_PYR-GCK LARHG-----LGVAILPQSMARGGSGLHALRLAPELRGRLVWAWRADGAN
Mvan_3362|M.vanbaalenii_PYR-1 LARHG-----LGVAILPRSMARGSAGLHPLRLSPELRGRLVWAWRTDISG
Mb0384|M.bovis_AF2122/97 VMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQP
Rv0377|M.tuberculosis_H37Rv VMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATLAPSARQP
TH_3504|M.thermoresistible__bu APLTTG-----GIAFVTAAAGPTMNGRVQVVDLTPPLLVPVQALWQRHTL
*.:.
MAV_0094|M.avium_104 ALLSTV-----DTAVRDLLATAT----------------
MSMEG_2544|M.smegmatis_MC2_155 GLLATV-----DTAVRELLNDDRPSGTMVAKTSVKVSA-
MAB_3179c|M.abscessus_ATCC_199 VAFNAV-----KDAAREALSGESAAIA------------
MMAR_2756|M.marinum_M SSGRDE-----AYRQLAAIMGESISNEQQVRLVN-----
MUL_2998|M.ulcerans_Agy99 SSGRDE-----AYRQLAAIMGESISNEQQVRLVN-----
MLBr_02041|M.leprae_Br4923 ASGRSA-----SYRQIAKIIGELISTEHHVRLVA-----
Mflv_3565|M.gilvum_PYR-GCK PAARVL-----GERARAMAVSPGSGAPAVVPGA------
Mvan_3362|M.vanbaalenii_PYR-1 PAARLL-----NARARAMIAATG--TPAVIPGA------
Mb0384|M.bovis_AF2122/97 AVSELVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv AVSELVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
TH_3504|M.thermoresistible__bu SAIRDR-----------ILEGLG----------------