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ASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQHVRKLETAIGEPVVRRYGRGVVFTDRGARLLV HARRILAAHDAAVDDLVAGQERALVLGVTEHGADLILPSITSALRSHLPDWSVRVRFDRNLYLAESVDRG IMDLAVILDGSGLDRANAVGTVPLQWVAARGYKPNPIEPLRVMTFTEPCTLRAPMFSALHTLGNQYQIVG ESPDLSGLYAGLRSGLGMALLPIIGWLPDGIAPVDAMPAANLATLSVVGRRGLDPVAFNAVKDAAREALS GESAAIA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_3179c | - | - | 100% (288) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 3e-15 | 28.93% (242) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4730 | - | 1e-14 | 27.51% (269) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb0384 | - | 2e-08 | 28.37% (141) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 2e-12 | 27.53% (247) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv0377 | - | 2e-08 | 28.37% (141) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 2e-12 | 33.10% (145) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 4e-10 | 31.72% (145) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_0094 | - | 6e-90 | 58.18% (275) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_2544 | - | 4e-90 | 59.57% (277) | transcriptional regulator, LysR family protein |
| M. thermoresistible (build 8) | TH_3504 | - | 2e-11 | 32.78% (180) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 3e-10 | 31.72% (145) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 1e-13 | 28.46% (246) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MAV_0094|M.avium_104 -----------MGQVLDIAPLRSLVAVADCGGFHRAAAALHLSQSAVSQH
MSMEG_2544|M.smegmatis_MC2_155 -----------MGQVLDIAPLRSLVAVADCGGFHRAAAVLHLTQSAVSQH
MAB_3179c|M.abscessus_ATCC_199 ----------MASSTFDIAPLRSLAAVADCGGFHRAAAVLHLTQSAVSQH
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MLBr_02041|M.leprae_Br4923 --------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQA
Mb0384|M.bovis_AF2122/97 ---------------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMH
Rv0377|M.tuberculosis_H37Rv ---------------MTPAQLRAYSAVVRLGSVRAAAAELGLSDAGVSMH
Mflv_3565|M.gilvum_PYR-GCK ---------------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQ
Mvan_1027|M.vanbaalenii_PYR-1 --------------MFSLARLSCFVAVAEELHFGRAAERLHMTQPPLSRQ
TH_3504|M.thermoresistible__bu ----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSA
* *:. . ** : : :*
MAV_0094|M.avium_104 LRRIEAVVGEPIVQRSGRGVVFTEVGQKALRHARTILAAHDTALDDLGAT
MSMEG_2544|M.smegmatis_MC2_155 VRRLEGVVGGPIVQRSGRGMAFTELGHRVVAHARRILAAHDAALADLGAA
MAB_3179c|M.abscessus_ATCC_199 VRKLETAIGEPVVRRYGRGVVFTDRGARLLVHARRILAAHDAAVDDLVAG
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MLBr_02041|M.leprae_Br4923 LAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGE
Mb0384|M.bovis_AF2122/97 VAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEA
Rv0377|M.tuberculosis_H37Rv VAALRKELDDPLFTRTGAGLAFTPGGLRLASRAVEILGLQQQTAIEVTEA
Mflv_3565|M.gilvum_PYR-GCK IRRLERSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDV
Mvan_1027|M.vanbaalenii_PYR-1 VQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQLAEGAAQTVKRI
TH_3504|M.thermoresistible__bu VRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQT
: :. :. :. * : .* * . :
MAV_0094|M.avium_104 EN---KVLTIGATEHGADVMLAGLSGALRDRLPDLRVRFRLDRNVSLADS
MSMEG_2544|M.smegmatis_MC2_155 EE---KTLLIGATEHGADVMLPGLNDALAECLPDWRVRFRLDRNVALADA
MAB_3179c|M.abscessus_ATCC_199 QE---RALVLGVTEHGADLILPSITSALRSHLPDWSVRVRFDRNLYLAES
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTA
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPTLTVRVIEDQTERLLTA
MLBr_02041|M.leprae_Br4923 SDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLTA
Mb0384|M.bovis_AF2122/97 AHG-RRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFREL
Rv0377|M.tuberculosis_H37Rv AHG-RRLLRIAASSAFAEHAAPGLIELFSSRADDLSVELSVHPTSRFREL
Mflv_3565|M.gilvum_PYR-GCK AGLLRGSVAIG-TVTLHPMNVAHLIAEFHADHPDVEITLGTATSDVLIAE
Mvan_1027|M.vanbaalenii_PYR-1 PAGDLGTVVVGFTAASAHAVLPRLLERARERLPDVKLDLREMVTAAQIEG
TH_3504|M.thermoresistible__bu EAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPSTSFTLRQLYPDALTDA
.. : . .
MAV_0094|M.avium_104 IDRGLVDVAIMLDGAG----LDRANASGLVRLQWVSAR-----------T
MSMEG_2544|M.smegmatis_MC2_155 IEHGTVDVAVMLDGSG----WDRVNASGMVPLKWISAR-----------N
MAB_3179c|M.abscessus_ATCC_199 VDRGIMDLAVILDGSG----LDRANAVGTVPLQWVAAR-----------G
MMAR_2756|M.marinum_M LREGSLDTALIALPAD----YGGLTEIPIYEEDFVLALPPGHPMADRH-G
MUL_2998|M.ulcerans_Agy99 LREGSLDTALIALPAD----YGGLTEIPIYEEDFVLALPPGHPMADRH-G
MLBr_02041|M.leprae_Br4923 LREGALDAAMIALPVE----TAGIAEIPIYDEDFVLALPPGHPLSGKR-R
Mb0384|M.bovis_AF2122/97 ICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAP---------N
Rv0377|M.tuberculosis_H37Rv ICSRAVDIAIGPASESSIGSDGSIFLRPFLKYQIITVVAP---------N
Mflv_3565|M.gilvum_PYR-GCK LGDGRLDLAIVSIAVD--EDLPGLEVAVITDEAVEAAVADGHPLAHRR-S
Mvan_1027|M.vanbaalenii_PYR-1 LMTGELDLGMARPPLK----RPGLVSRPLLHEQLLAALPEGHPLADMTRE
TH_3504|M.thermoresistible__bu VFDGTVQLGLRRGVVP----TPELATAVIGYHRVRVAFVDSHPLAAR-ES
: :: .: .
MAV_0094|M.avium_104 LTIAPKDPLPLVIFSEPCTLR-------EPAFAILDSHRIDYEIAAE-CG
MSMEG_2544|M.smegmatis_MC2_155 FGCD-GEPLPVVVYSEPCTLR-------EPAFAALEKLEVDYQIVAE-CA
MAB_3179c|M.abscessus_ATCC_199 YKPNPIEPLRVMTFTEPCTLR-------APMFSALHTLGNQYQIVGE-SP
MMAR_2756|M.marinum_M VPVAALSELPLLLLDEGHCLR-------DQALDVCQNAGVRAELADTRAA
MUL_2998|M.ulcerans_Agy99 VPVAALSELPLLLLDEGHCLR-------DQALDVCQNAGVRAEHADTRAD
MLBr_02041|M.leprae_Br4923 VPTTALAQLPLLLLDEGHCLR-------DQTLDICRKSGVQAELANTRAA
Mb0384|M.bovis_AF2122/97 SPLAAGIPMPALLRHQQWMLGPSAGSVDGEIATMLRGLAIPESQQRIFQS
Rv0377|M.tuberculosis_H37Rv SPLAAGIPMPALLRHQQWMLGPSAGSVDGEIATMLRGLAIPESQQRIFQS
Mflv_3565|M.gilvum_PYR-GCK LSLEQLSRHPLISLPAGTGLR-------TRLDTACAAAGLRPR-IAFEAT
Mvan_1027|M.vanbaalenii_PYR-1 LTLIDLDGQDFVMYSPVQARYFN-----ELLISTFTIAGTTPRYVQY-VT
TH_3504|M.thermoresistible__bu VDITELAREQVALWAPPGTSYYS-----DFLMGACRRAGFEPDYVVSRVQ
MAV_0094|M.avium_104 DLSGLYAAVRSG-----LGVALLPMIG------KFPDGLGPAEGLPPANN
MSMEG_2544|M.smegmatis_MC2_155 DLSGLIAAVRSG-----LGIALLPMIG------RLPDGLTVADTMPEANR
MAB_3179c|M.abscessus_ATCC_199 DLSGLYAGLRSG-----LGMALLPIIG------WLPDGIAPVDAMPAANL
MMAR_2756|M.marinum_M SLATAVQCVNGG-----LGVTLIPQSAVSVEAARSRVGLAHFAAPTPGRR
MUL_2998|M.ulcerans_Agy99 SLATAVQCVNGG-----LGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRR
MLBr_02041|M.leprae_Br4923 SLATAVQCVTGG-----LGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRR
Mb0384|M.bovis_AF2122/97 DAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATL
Rv0377|M.tuberculosis_H37Rv DAAALEEVMRVGGATLAIGFAVAKDLAAGRLVHVTGPGLDRAGEWCVATL
Mflv_3565|M.gilvum_PYR-GCK SPAELAELARHG-----LGVAILPQSMA-----RGGSGLHALRLAPELRG
Mvan_1027|M.vanbaalenii_PYR-1 QVHTMLVLVRSG-----IGIALVPASAAT--LHPEGVVFRTIGAFRERPV
TH_3504|M.thermoresistible__bu GAATVAAPLTTG------GIAFVTAAAGP----TMNGRVQVVDLTPPLLV
* *.:. .
MAV_0094|M.avium_104 ASILVRGRTGIDPALLSTVDTAVRDLLATAT---------------
MSMEG_2544|M.smegmatis_MC2_155 ASVFVRGRAGVDSGLLATVDTAVRELLNDDRPSGTMVAKTSVKVSA
MAB_3179c|M.abscessus_ATCC_199 ATLSVVGRRGLDPVAFNAVKDAAREALSGESAAIA-----------
MMAR_2756|M.marinum_M IGLVYRASSGRD-EAYRQLAAIMGESISNEQQVRLVN---------
MUL_2998|M.ulcerans_Agy99 IGLVYRASSGRD-EAYRQLAAIMGESISNEQQVRLVN---------
MLBr_02041|M.leprae_Br4923 IGLAFRSASGRS-ASYRQIAKIIGELISTEHHVRLVA---------
Mb0384|M.bovis_AF2122/97 APSARQPAVSELVGFISTPRCIQAMIRGSGVGVTRFRPKVHVTLWS
Rv0377|M.tuberculosis_H37Rv APSARQPAVSELVGFISTPRCIQAMIPGSGVGVTRFRPKVHVTLWS
Mflv_3565|M.gilvum_PYR-GCK RLVWAWRADGANPAARVLGERARAMAVSPGSGAPAVVPGA------
Mvan_1027|M.vanbaalenii_PYR-1 ELDAVWRGDSTNPALLRVLKDVLPQQEWTT----------------
TH_3504|M.thermoresistible__bu PVQALWQRHTLSAIRDRILEGLG-----------------------