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MELSDITHFLAVAEAGGISHASKRLHTVQSNVSTHIKALEDELGVELFRRHARGMALTNAGEAFLPYAER ITALLREATQVVGDEAEPTGTLAIGSMETTAGLRLPGVLAAFAAACPRVDFTLATGTTAELIDMVTDRRL DGAFVCGPIENDSLTTDLAFVEELVLLTAQRHTEISEVFGAPTRMLVFRNGCSYRARLQQIFTEQGVDPQ VLEFGSLEGILGCVAADMGVSLLPAGVVSASQRATLLRMHPLPPMRARVETVFVRRADAALSPAMAQFLR ELQRADTPVVLRSVAP
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. abscessus ATCC 19977 | MAB_0161 | - | - | 100% (296) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_2238 | - | 3e-22 | 29.90% (291) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_3308 | - | 3e-20 | 29.49% (295) | LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 1e-09 | 27.31% (238) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 3e-22 | 30.41% (296) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 1e-09 | 27.31% (238) | LysR family transcriptional regulator |
| M. leprae Br4923 | MLBr_02041 | oxyR | 9e-17 | 26.45% (242) | putative LysR-family transcriptional regulator |
| M. marinum M | MMAR_2756 | oxyR | 5e-17 | 27.24% (246) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_1538 | - | 4e-18 | 27.69% (242) | transcriptional regulator, LysR family protein |
| M. smegmatis MC2 155 | MSMEG_3840 | - | 6e-24 | 31.93% (285) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 5e-12 | 29.30% (157) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 1e-16 | 27.24% (246) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_3362 | - | 9e-19 | 29.18% (305) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MLBr_02041|M.leprae_Br4923 --------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQA
Mflv_3565|M.gilvum_PYR-GCK ---------------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQ
Mvan_3362|M.vanbaalenii_PYR-1 ---------------MELRQLEYLVAVVEERSFTKAAQRERVAQPAVSAQ
MSMEG_3840|M.smegmatis_MC2_155 ---------------MELRQLEYFVAVAEEANFTRAAQRIHVAQPAVSAS
Mb2303c|M.bovis_AF2122/97 --------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRR
Rv2282c|M.tuberculosis_H37Rv --------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRR
MAV_1538|M.avium_104 ---------------MAVGDYEWFITLAELQHVTAAAEQLHVAQPTLTRM
MAB_0161|M.abscessus_ATCC_1997 ---------------MELSDITHFLAVAEAGGISHASKRLHTVQSNVSTH
TH_3504|M.thermoresistible__bu ----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSA
: ::::.* . *: * ::
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MLBr_02041|M.leprae_Br4923 LAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGE
Mflv_3565|M.gilvum_PYR-GCK IRRLERSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDV
Mvan_3362|M.vanbaalenii_PYR-1 IRRLERQVGQPLLTRSHRGVRVTPAGAALLPHARAALAAVRDAQAAVDDV
MSMEG_3840|M.smegmatis_MC2_155 IRQLERELGQPLFDRSRREVRLTAAGEAVLPHAHAALRSVAAARTAVAEV
Mb2303c|M.bovis_AF2122/97 LASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSL
Rv2282c|M.tuberculosis_H37Rv LASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSL
MAV_1538|M.avium_104 LARLEQRLGVALFDRHGRRLSLNTYGRIFYEHARRAQLELDSARRAIADL
MAB_0161|M.abscessus_ATCC_1997 IKALEDELGVELFRRHARGMALTNAGEAFLPYAERITALLREATQVVGDE
TH_3504|M.thermoresistible__bu VRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQT
: :* :. * * * :. * . .
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLP-----TLTVRVIEDQTE
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLP-----TLTVRVIEDQTE
MLBr_02041|M.leprae_Br4923 SDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLP-----TLTLRVVEDQTE
Mflv_3565|M.gilvum_PYR-GCK AGLLRGSVAIGTV-TLHPMNVAHLIAEFHADHP-----DVEITLGTATSD
Mvan_3362|M.vanbaalenii_PYR-1 ANLVRGAVAIGTV-TLHPVDVARLMADFHAEHP-----GVEITLGTDTSD
MSMEG_3840|M.smegmatis_MC2_155 SGLVRGSVVVGTV-TAHDFDMAGLLAEFHGAHQ-----LVDITLGTDESD
Mb2303c|M.bovis_AF2122/97 RTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSE
Rv2282c|M.tuberculosis_H37Rv RTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSE
MAV_1538|M.avium_104 ADPAVGEIRLAYLSSFGSTVVPRLIARFKESSP-----RVTFTLEEGAAE
MAB_0161|M.abscessus_ATCC_1997 AEP-TGTLAIGSMETTAGLRLPGVLAAFAAACP-----RVDFTLATGTTA
TH_3504|M.thermoresistible__bu EAAAQAHYVIGHTPALSGAEAYALIEPAVTAYP-----STSFTLRQLYPD
. : : . : .
MMAR_2756|M.marinum_M RLLTALREGSLDTALIALPAD--YGGLTEIPIYEEDFVLALPPGHPMADR
MUL_2998|M.ulcerans_Agy99 RLLTALREGSLDTALIALPAD--YGGLTEIPIYEEDFVLALPPGHPMADR
MLBr_02041|M.leprae_Br4923 HLLTALREGALDAAMIALPVE--TAGIAEIPIYDEDFVLALPPGHPLSGK
Mflv_3565|M.gilvum_PYR-GCK VLIAELGDGRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR
Mvan_3362|M.vanbaalenii_PYR-1 VLLAKLEDGRLDAAIVSIGADEDPAGLEYEVITDEALEAAVTAQHRLARR
MSMEG_3840|M.smegmatis_MC2_155 ALIDGLLAGRLDAAIISVGSG-LPEGLAAEVVTDQRIVAAVGDGHPWRRR
Mb2303c|M.bovis_AF2122/97 HAIAAVRDGIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARR
Rv2282c|M.tuberculosis_H37Rv HAIAAVRDGIADLGFIENPCP--PTGLGSVVVARDELVVVVPPGHKWARR
MAV_1538|M.avium_104 SIADRVRSGGVDIGVVSPRPV--ERTLAWRSLFRQRLGVAVPDGHRFARG
MAB_0161|M.abscessus_ATCC_1997 ELIDMVTDRRLDGAFVCGPIE--NDSLTTDLAFVEELVLLTAQRH-----
TH_3504|M.thermoresistible__bu ALTDAVFDGTVQLGLRRGVVP--TPELATAVIGYHRVRVAFVDSHPLAAR
: : .. : . . *
MMAR_2756|M.marinum_M -HGVPVAALSELPLLLLDEG--HCLRDQALDVCQN---AGVRAELADTRA
MUL_2998|M.ulcerans_Agy99 -HGVPVAALSELPLLLLDEG--HCLRDQALDVCQN---AGVRAEHADTRA
MLBr_02041|M.leprae_Br4923 -RRVPTTALAQLPLLLLDEG--HCLRDQTLDICRK---SGVQAELANTRA
Mflv_3565|M.gilvum_PYR-GCK -RSLSLEQLSRHPLISLPAG--TGLRTRLDTACAA---AGLRPRIAFEAT
Mvan_3362|M.vanbaalenii_PYR-1 -KSLSLKQLCEYPVISLPAG--TGLRSRLDDACAA---AGLRPRIAFEAT
MSMEG_3840|M.smegmatis_MC2_155 -RRIALTDLAGVPLITLPRG--TGIRRQLDRACRA---AGVDVRVAFEAT
Mb2303c|M.bovis_AF2122/97 SRVVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLEL
Rv2282c|M.tuberculosis_H37Rv SRVVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLEL
MAV_1538|M.avium_104 -AAVSMVDLADEPFVTMHPG--FGMRRLLDELCAA---AQFRPRVALQAP
MAB_0161|M.abscessus_ATCC_1997 -TEISEVFGAPTRMLVFRNG--CSYRARLQQIFTE-----QGVDPQVLEF
TH_3504|M.thermoresistible__bu -ESVDITELAREQVALWAPPGTSYYSDFLMGACRR---AGFEPDYVVSRV
: . .
MMAR_2756|M.marinum_M ASLATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLAHFAAPTPGRRIGLV
MUL_2998|M.ulcerans_Agy99 DSLATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRRIGLV
MLBr_02041|M.leprae_Br4923 ASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLA
Mflv_3565|M.gilvum_PYR-GCK SPAELAELARHG-LGVAILPQSMARGGSGLHALRLA----PELRGRLVWA
Mvan_3362|M.vanbaalenii_PYR-1 SPLELADLARHG-LGVAILPRSMARGSAGLHPLRLS----PELRGRLVWA
MSMEG_3840|M.smegmatis_MC2_155 TPGALADLAERG-LGAAVLPESVARARAALHPLPIT----PELRGRLVFA
Mb2303c|M.bovis_AF2122/97 SSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAI
Rv2282c|M.tuberculosis_H37Rv SSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAI
MAV_1538|M.avium_104 NLTTAASLVAAG-LGISLVPIDGSSYPSGVSVKPLAD---ADAYRDVGMI
MAB_0161|M.abscessus_ATCC_1997 GSLEGILGCVAADMGVSLLPAGVVSASQRATLLRMHPLPPMRARVETVFV
TH_3504|M.thermoresistible__bu QGAATVAAPLTTGGIAFVTAAAGPTMNGRVQVVDLT----PPLLVPVQAL
.
MMAR_2756|M.marinum_M YRASSGRDEAYRQLAAIMGESISNEQ---QVRLVN--
MUL_2998|M.ulcerans_Agy99 YRASSGRDEAYRQLAAIMGESISNEQ---QVRLVN--
MLBr_02041|M.leprae_Br4923 FRSASGRSASYRQIAKIIGELISTEH---HVRLVA--
Mflv_3565|M.gilvum_PYR-GCK WRADGAN-PAARVLGERARAMAVSPGSGAPAVVPGA-
Mvan_3362|M.vanbaalenii_PYR-1 WRTDISG-PAARLLNARARAMIAATG--TPAVIPGA-
MSMEG_3840|M.smegmatis_MC2_155 WRATGPMSPAARALVTMARRRLGLGD---PDRVGGHE
Mb2303c|M.bovis_AF2122/97 WVG--GRTPPAGAIRDLLSHITSRST-----------
Rv2282c|M.tuberculosis_H37Rv WVG--GRTPPAGAIRDLLSHITSRST-----------
MAV_1538|M.avium_104 WDSGRPLPRSARDFIAGAAAVGHGGW-----------
MAB_0161|M.abscessus_ATCC_1997 RRADAALSPAMAQFLRELQRADTPVVLRSVAP-----
TH_3504|M.thermoresistible__bu WQRHTLSAIRDRILEGLG-------------------
: