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SDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQALAALESGLGVQLIERSTRRVFVTTQGRHL LPRAQAAIEAMDAFTAAAAGESDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPTLTLRVVEDQTEHLLT ALREGALDAAMIALPVETAGIAEIPIYDEDFVLALPPGHPLSGKRRVPTTALAQLPLLLLDEGHCLRDQT LDICRKSGVQAELANTRAASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLAFR SASGRSASYRQIAKIIGELISTEHHVRLVA*
Operon Prediction Model: Genebank
Paralogs
| species | id | gene | e-value | identity (len) | annotation |
| M. leprae Br4923 | MLBr_02041 | oxyR | - | 100% (311) | putative LysR-family transcriptional regulator |
| M. leprae Br4923 | MLBr_02663 | oxyS | 6e-16 | 26.10% (295) | putative LysR family transcriptional regulator |
Closest Orthologs (e-value cutoff: 1e-4)
| species | id | gene | e-value | identity (len) | annotation |
| M. bovis AF2122 / 97 | Mb2303c | - | 6e-17 | 27.23% (213) | LysR family transcriptional regulator |
| M. gilvum PYR-GCK | Mflv_3565 | - | 8e-25 | 31.38% (290) | LysR family transcriptional regulator |
| M. tuberculosis H37Rv | Rv2282c | - | 6e-17 | 27.23% (213) | LysR family transcriptional regulator |
| M. abscessus ATCC 19977 | MAB_4409 | - | 1e-101 | 58.63% (307) | hydrogen peroxide-inducible genes activator |
| M. marinum M | MMAR_2756 | oxyR | 1e-129 | 72.58% (310) | hydrogen peroxide-inducible genes activator, OxyR |
| M. avium 104 | MAV_2838 | - | 1e-137 | 79.35% (310) | hydrogen peroxide-inducible genes activator |
| M. smegmatis MC2 155 | MSMEG_3840 | - | 8e-26 | 33.61% (244) | LysR-family protein transcriptional regulator |
| M. thermoresistible (build 8) | TH_3504 | - | 2e-14 | 25.30% (249) | PUTATIVE putative transcriptional regulator |
| M. ulcerans Agy99 | MUL_2998 | oxyR | 1e-127 | 71.29% (310) | hydrogen peroxide-inducible genes activator, OxyR |
| M. vanbaalenii PYR-1 | Mvan_1027 | - | 2e-22 | 32.44% (262) | LysR family transcriptional regulator |
CLUSTAL 2.0.9 multiple sequence alignment
MLBr_02041|M.leprae_Br4923 --------MSDKSYQPTIAGLRAFVAVVEKGHFSAAASFLGVRQSTLSQA
MAV_2838|M.avium_104 --------MPDKTYQPTIAGLRAFVAVAEKRQFSGAATALGVSQSTLSQA
MMAR_2756|M.marinum_M MLATILIGMTDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MUL_2998|M.ulcerans_Agy99 -----MIGITDKSYQPTLAGLRAFVAVAEKQHFGSAANALGVSQSTLSQA
MAB_4409|M.abscessus_ATCC_1997 --------MSDRSYQPTVVGLRAFVAIARKRHFGSAAGELGVSQPSLSQA
Mflv_3565|M.gilvum_PYR-GCK ---------------MELRQLEYFVAIVEEGGFTRAASRERVAQPAVSAQ
MSMEG_3840|M.smegmatis_MC2_155 ---------------MELRQLEYFVAVAEEANFTRAAQRIHVAQPAVSAS
Mb2303c|M.bovis_AF2122/97 --------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRR
Rv2282c|M.tuberculosis_H37Rv --------MPLSSRMPGLTCFEIFLAIAEAGSLGGAARELGLTQQAVSRR
Mvan_1027|M.vanbaalenii_PYR-1 --------------MFSLARLSCFVAVAEELHFGRAAERLHMTQPPLSRQ
TH_3504|M.thermoresistible__bu ----------VPSPKIDLRRLAQFVAVAELGSFTRAAATLHLSQQALSSA
: : *:*:.. : ** : * .:*
MLBr_02041|M.leprae_Br4923 LAALESGLGVQLIERSTRRVFVTTQGRHLLPRAQAAIEAMDAFTAAAAGE
MAV_2838|M.avium_104 LAALEAGLGTQLVERSTRRVFLTPQGAELLPHAQAVVEAADAFTAAAAGS
MMAR_2756|M.marinum_M LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MUL_2998|M.ulcerans_Agy99 LAALEAGLDLHLVERSTRRVFLTTEGRSLLPHAQAAVEAVEAFTTAAAGE
MAB_4409|M.abscessus_ATCC_1997 LSMLEEGLGVRLVERNTRKVLLTPEGDALLEKAISALNAVDEFTSAASGV
Mflv_3565|M.gilvum_PYR-GCK IRRLERSVGQPLLTRTSREVRLTRAGEALLPHARAALAAVRDGRAAVDDV
MSMEG_3840|M.smegmatis_MC2_155 IRQLERELGQPLFDRSRREVRLTAAGEAVLPHAHAALRSVAAARTAVAEV
Mb2303c|M.bovis_AF2122/97 LASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSL
Rv2282c|M.tuberculosis_H37Rv LASMEAQIGVRLAIRTTRGSQLTPAGIVVAEWAARLLEVADEIDAGLGSL
Mvan_1027|M.vanbaalenii_PYR-1 VQQLENELGVQLIDRTTRNVTLTPAGAAFLPDARRILQLAEGAAQTVKRI
TH_3504|M.thermoresistible__bu VRALENDVGADLFTRDGRRISLTTAGRTLLAEGKPLLAAARTVAEHVRQT
: :* :. * * * :* * . . :
MLBr_02041|M.leprae_Br4923 SDPLRGGMRLGLIPTVAPYVLPTMLTGLTHRLPT-----LTLRVVEDQTE
MAV_2838|M.avium_104 ADPLRAGMRLGLIPTVAPYVLPTVLAGIAERRPG-----LTLRVTEDQTE
MMAR_2756|M.marinum_M ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPT-----LTVRVIEDQTE
MUL_2998|M.ulcerans_Agy99 ADPLNGSIRFGIIPTVAPYVLPTVLAGLTRRLPT-----LTVRVIEDQTE
MAB_4409|M.abscessus_ATCC_1997 RDPFAQTLRLGLIPTVAPYVLPMVLSGLSREFPE-----MSLRVTEDQTH
Mflv_3565|M.gilvum_PYR-GCK AGLLRGSVAIGTV-TLHPMNVAHLIAEFHADHPD-----VEITLGTATSD
MSMEG_3840|M.smegmatis_MC2_155 SGLVRGSVVVGTV-TAHDFDMAGLLAEFHGAHQL-----VDITLGTDESD
Mb2303c|M.bovis_AF2122/97 RTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSE
Rv2282c|M.tuberculosis_H37Rv RTEGRQRIRVVASQTIAEQLMPHWMLSLRAADMRRGGTVPEVILTATNSE
Mvan_1027|M.vanbaalenii_PYR-1 PAGDLGTVVVGFTAASAHAVLPRLLERARERLPD-----VKLDLREMVTA
TH_3504|M.thermoresistible__bu EAAAQAHYVIGHTPALSGAEAYALIEPAVTAYPS-----TSFTLRQLYPD
. : : . : .
MLBr_02041|M.leprae_Br4923 HLLTALREGALDAAMIALPVETA--GIAEIPIYDEDFVLALPPGHPLSGK
MAV_2838|M.avium_104 RLLAVLREGALDAALIALPAETA--GVTAIPIYDEDFVLALPPGHPLAGK
MMAR_2756|M.marinum_M RLLTALREGSLDTALIALPADYG--GLTEIPIYEEDFVLALPPGHPMADR
MUL_2998|M.ulcerans_Agy99 RLLTALREGSLDTALIALPADYG--GLTEIPIYEEDFVLALPPGHPMADR
MAB_4409|M.abscessus_ATCC_1997 RLLRSLSDGTLDVAVMALPVQTQ--GMAEIPMYREDFVLALPSGHPLAGS
Mflv_3565|M.gilvum_PYR-GCK VLIAELGDGRLDLAIVSIAVDEDLPGLEVAVITDEAVEAAVADGHPLAHR
MSMEG_3840|M.smegmatis_MC2_155 ALIDGLLAGRLDAAIISVGSGLP-EGLAAEVVTDQRIVAAVGDGHPWRRR
Mb2303c|M.bovis_AF2122/97 HAIAAVRDGIADLGFIENPCPPT--GLGSVVVARDELVVVVPPGHKWARR
Rv2282c|M.tuberculosis_H37Rv HAIAAVRDGIADLGFIENPCPPT--GLGSVVVARDELVVVVPPGHKWARR
Mvan_1027|M.vanbaalenii_PYR-1 AQIEGLMTGELDLGMARPPLKRP--GLVSRPLLHEQLLAALPEGHPLADM
TH_3504|M.thermoresistible__bu ALTDAVFDGTVQLGLRRGVVPTP--ELATAVIGYHRVRVAFVDSHPLAAR
: * : .. : : . . .. .*
MLBr_02041|M.leprae_Br4923 -RRVPTTALAQLPLLLLDEG--HCLRDQTLDICRK---SGVQAELANTRA
MAV_2838|M.avium_104 -RRVPATALADLPLLLLDEG--HCLRDQALDVCHK---AGVRAELANTRA
MMAR_2756|M.marinum_M -HGVPVAALSELPLLLLDEG--HCLRDQALDVCQN---AGVRAELADTRA
MUL_2998|M.ulcerans_Agy99 -HGVPVAALSELPLLLLDEG--HCLRDQALDVCQN---AGVRAEHADTRA
MAB_4409|M.abscessus_ATCC_1997 -KNVEPADLADMPLLLLDEG--HCLRDQALEVCQL---AGVRPDLGHTRA
Mflv_3565|M.gilvum_PYR-GCK -RSLSLEQLSRHPLISLPAG--TGLRTRLDTACAA---AGLRPRIA-FEA
MSMEG_3840|M.smegmatis_MC2_155 -RRIALTDLAGVPLITLPRG--TGIRRQLDRACRA---AGVDVRVA-FEA
Mb2303c|M.bovis_AF2122/97 SRVVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLEL
Rv2282c|M.tuberculosis_H37Rv SRVVSARELAQTPLVTREPN--SGIRDSLTAALRDTLGEDMQQAPPVLEL
Mvan_1027|M.vanbaalenii_PYR-1 TRELTLIDLDGQDFVMYSPV--QARYFNELLISTFT--IAGTTPRYVQYV
TH_3504|M.thermoresistible__bu -ESVDITELAREQVALWAPPGTSYYSDFLMGACRR---AGFEPDYVVSRV
. : * .
MLBr_02041|M.leprae_Br4923 ASLATAVQCVTGGLGVTLLPQSAAPVESVRSKLGLAQFAAPCPGRRIGLA
MAV_2838|M.avium_104 ASLATAVQCVTGGLGVTLIPQSAVPVEASRSRLGLAQFAAPRPGRRIGLV
MMAR_2756|M.marinum_M ASLATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLAHFAAPTPGRRIGLV
MUL_2998|M.ulcerans_Agy99 DSLATAVQCVNGGLGVTLIPQSAVSVEAARSRVGLTHFAAPTPGRRIGLV
MAB_4409|M.abscessus_ATCC_1997 ASLATAVQCVEGGLGVTLIPGTAVTAETASGGLATATFAAPVPGRRIGLV
Mflv_3565|M.gilvum_PYR-GCK TSPAELAELARHGLGVAILPQSMARGGSGLHALRLA----PELRGRLVWA
MSMEG_3840|M.smegmatis_MC2_155 TTPGALADLAERGLGAAVLPESVARARAALHPLPIT----PELRGRLVFA
Mb2303c|M.bovis_AF2122/97 SSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAI
Rv2282c|M.tuberculosis_H37Rv SSAAAVRAAVLAGAGPAAMSRLAIADDLAFGRLLAVDIPALNLRRQLRAI
Mvan_1027|M.vanbaalenii_PYR-1 TQVHTMLVLVRSGIGIALVPASAATLHPEGVVFRTIG-AFRERPVELDAV
TH_3504|M.thermoresistible__bu QGAATVAAPLTTG-GIAFVTAAAGPTMNGRVQVVDLT---PPLLVPVQAL
* * : :. . :
MLBr_02041|M.leprae_Br4923 FRSASGRSASYRQIAKIIG---ELISTEHHVRLVA--
MAV_2838|M.avium_104 FRSSSGRDDSYRELAGLIG---ELISSQHQVRLVK--
MMAR_2756|M.marinum_M YRASSGRDEAYRQLAAIMG---ESISNEQQVRLVN--
MUL_2998|M.ulcerans_Agy99 YRASSGRDEAYRQLAAIMG---ESISNEQQVRLVN--
MAB_4409|M.abscessus_ATCC_1997 YRAISAREDAYRRLAELLT---RLVSAVHPVTADAA-
Mflv_3565|M.gilvum_PYR-GCK WRADG-ANPAARVLGERARAMAVSPGSGAPAVVPGA-
MSMEG_3840|M.smegmatis_MC2_155 WRATGPMSPAARALVTMAR---RRLGLGDPDRVGGHE
Mb2303c|M.bovis_AF2122/97 W--VGGRTPPAGAIRDLLS----HITSRST-------
Rv2282c|M.tuberculosis_H37Rv W--VGGRTPPAGAIRDLLS----HITSRST-------
Mvan_1027|M.vanbaalenii_PYR-1 WRGDSTNPALLRVLKDVLP------QQEWTT------
TH_3504|M.thermoresistible__bu WQRHTLSAIRDRILEGLG-------------------
: :